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The map label for this gene is trpD [H]

Identifier: 150396622

GI number: 150396622

Start: 1489869

End: 1490882

Strand: Direct

Name: trpD [H]

Synonym: Smed_1408

Alternate gene names: 150396622

Gene position: 1489869-1490882 (Clockwise)

Preceding gene: 150396621

Following gene: 150396623

Centisome position: 39.39

GC content: 64.6

Gene sequence:

>1014_bases
ATGAGTGATTTGAAACCGTTCGTCGCCAAAGTCGCAGCGCGCGAGGCACTTAGCCGCGACGATGCACGCGCGGCCTTCGA
GATCATCATGTCCGGGGCGGCCACGCCGTCGCAGATCGGCGGCTTTCTCATGGCGCTCCGTGTACGCGGCGAAACGGTCG
ACGAGATCGTGGGTGCCGTCGGGGCGATGCGTGCACGCATGTTGCACGTGAAGGCGCCGGACGGTTCGATCGACATTGTC
GGCACCGGCGGCGACGGCGCCGGCACCTACAATATTTCGACGTTGGCCGCGCTGATCGTTGCAGGCGCGGGGGTGCCGGT
CGCCAAGCACGGCAACCGTGCGCTGAGCTCGAAATCAGGAACGGCCGATGCGCTCTCCTGCCTGGGCGTCAATCTCGAAA
TAGGGCCCGAGGCAATCTCGCGCTGCATCGGCGAAGCCGGTCTGGGCTTCATGTTCGCGCAGCAGCACCATTCGGCTATG
CGCCATGTCGGTCCGACGCGGGTGGAACTCGGAACGAGAACGATCTTCAACCTGCTCGGCCCCCTCGCCAATCCGGCCGG
CGTTCGGCAACAGCTCGTCGGCGTCTACGCGCCGCAATGGGTCGATCCGCTGGCAGAGGTGCTCCGCGATCTCGGCTCCG
AGAGTGTCTGGGTCGTCCATGGCGAAGGGCTCGACGAGATCACGACGACCGGAGTGACCAAGGTTGCGGCGCTCAAGGAC
GGCACGATCACCAACTTCGAACTGACACCGGCCGATTTCGGGCTCGAGCGCGTTACGCTCGATGCCTTGAAGGGCGGTGA
CGGCGCCCATAACGCCGCCGCGCTGCAAGCTGTTCTCGACGGTGCGGAGAATGCCTACCGGGACATTTCCCTTGCGAACG
CCGCCGCTTCGTTGATGATAGCGGGGCGCGCAAAGGACCTGATGGAGGGCATGGACTTGGCCCGGAAATCGCTTTCGAGC
GGCGCCGCAAAGGTCGCCTTGCAGCGATTGATCACCGTTTCGAACGCGGCATGA

Upstream 100 bases:

>100_bases
TCAGATGGTCTCGACACTGCAAACCGCCTATGGCGTCTCGATCAACCAGACGCTTGCCGAAACGGCGCTGGCGCAACGGT
GACGACGGAGAAGTGAATTC

Downstream 100 bases:

>100_bases
GGAAAAGACATGACGGACATCCTGCGTCGGATCGAAGCCTATAAGCGCGGCGAGATCGCGGCCGCGAAAGTACGTATTCC
GCTGGCCGAATTGAAGGCGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSDLKPFVAKVAAREALSRDDARAAFEIIMSGAATPSQIGGFLMALRVRGETVDEIVGAVGAMRARMLHVKAPDGSIDIV
GTGGDGAGTYNISTLAALIVAGAGVPVAKHGNRALSSKSGTADALSCLGVNLEIGPEAISRCIGEAGLGFMFAQQHHSAM
RHVGPTRVELGTRTIFNLLGPLANPAGVRQQLVGVYAPQWVDPLAEVLRDLGSESVWVVHGEGLDEITTTGVTKVAALKD
GTITNFELTPADFGLERVTLDALKGGDGAHNAAALQAVLDGAENAYRDISLANAAASLMIAGRAKDLMEGMDLARKSLSS
GAAKVALQRLITVSNAA

Sequences:

>Translated_337_residues
MSDLKPFVAKVAAREALSRDDARAAFEIIMSGAATPSQIGGFLMALRVRGETVDEIVGAVGAMRARMLHVKAPDGSIDIV
GTGGDGAGTYNISTLAALIVAGAGVPVAKHGNRALSSKSGTADALSCLGVNLEIGPEAISRCIGEAGLGFMFAQQHHSAM
RHVGPTRVELGTRTIFNLLGPLANPAGVRQQLVGVYAPQWVDPLAEVLRDLGSESVWVVHGEGLDEITTTGVTKVAALKD
GTITNFELTPADFGLERVTLDALKGGDGAHNAAALQAVLDGAENAYRDISLANAAASLMIAGRAKDLMEGMDLARKSLSS
GAAKVALQRLITVSNAA
>Mature_336_residues
SDLKPFVAKVAAREALSRDDARAAFEIIMSGAATPSQIGGFLMALRVRGETVDEIVGAVGAMRARMLHVKAPDGSIDIVG
TGGDGAGTYNISTLAALIVAGAGVPVAKHGNRALSSKSGTADALSCLGVNLEIGPEAISRCIGEAGLGFMFAQQHHSAMR
HVGPTRVELGTRTIFNLLGPLANPAGVRQQLVGVYAPQWVDPLAEVLRDLGSESVWVVHGEGLDEITTTGVTKVAALKDG
TITNFELTPADFGLERVTLDALKGGDGAHNAAALQAVLDGAENAYRDISLANAAASLMIAGRAKDLMEGMDLARKSLSSG
AAKVALQRLITVSNAA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=321, Percent_Identity=39.2523364485981, Blast_Score=212, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320561, Length=364, Percent_Identity=30.4945054945055, Blast_Score=129, Evalue=8e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 34685; Mature: 34554

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKPFVAKVAAREALSRDDARAAFEIIMSGAATPSQIGGFLMALRVRGETVDEIVGAV
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
GAMRARMLHVKAPDGSIDIVGTGGDGAGTYNISTLAALIVAGAGVPVAKHGNRALSSKSG
HHHHHHEEEEECCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
TADALSCLGVNLEIGPEAISRCIGEAGLGFMFAQQHHSAMRHVGPTRVELGTRTIFNLLG
CHHHHHHHCCCEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
PLANPAGVRQQLVGVYAPQWVDPLAEVLRDLGSESVWVVHGEGLDEITTTGVTKVAALKD
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCHHHEEEECC
GTITNFELTPADFGLERVTLDALKGGDGAHNAAALQAVLDGAENAYRDISLANAAASLMI
CCEEEEEECCHHCCHHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRAKDLMEGMDLARKSLSSGAAKVALQRLITVSNAA
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDLKPFVAKVAAREALSRDDARAAFEIIMSGAATPSQIGGFLMALRVRGETVDEIVGAV
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
GAMRARMLHVKAPDGSIDIVGTGGDGAGTYNISTLAALIVAGAGVPVAKHGNRALSSKSG
HHHHHHEEEEECCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
TADALSCLGVNLEIGPEAISRCIGEAGLGFMFAQQHHSAMRHVGPTRVELGTRTIFNLLG
CHHHHHHHCCCEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
PLANPAGVRQQLVGVYAPQWVDPLAEVLRDLGSESVWVVHGEGLDEITTTGVTKVAALKD
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCHHHEEEECC
GTITNFELTPADFGLERVTLDALKGGDGAHNAAALQAVLDGAENAYRDISLANAAASLMI
CCEEEEEECCHHCCHHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRAKDLMEGMDLARKSLSSGAAKVALQRLITVSNAA
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]