Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 150396621

GI number: 150396621

Start: 1487958

End: 1489850

Strand: Direct

Name: ppiD [H]

Synonym: Smed_1407

Alternate gene names: 150396621

Gene position: 1487958-1489850 (Clockwise)

Preceding gene: 150396615

Following gene: 150396622

Centisome position: 39.34

GC content: 63.07

Gene sequence:

>1893_bases
ATGCTCGACTCCCTGAGAAACGCCGCCCAGACCCGGGTCGTCAAAGCCCTGCTGGCCCTTCTCATCCTCTCATTTATGGT
GTGGGGTGGTCAGACGTTGATGGTGCCAAACACGCCCAATGCGGTGGTTACCGTCGGCGACATCAAGGTGTCGCCGAGCG
ACTTCCGGCTGGCCTACGAGCGGCAGGTGGCTTTGCTTTCGAGACAGCTCGGTACGCCGCTGACGCGTCAGCAGGCGCAA
GCCTTCGGGGTTGAAAACCAGGTCTATGCCCAACTGGTGGCAGGCGCGGCACTCGACCAGCTCGCCACCGACATGAATCT
CGGCCTGTCCGAGGACAGGCTGGCGCGGCTGATCGGCGAAGACCCGGCCTTCCACGGCGTCAACGGCCAATTCGATCGGC
TGACATTCTCCAGCGTTCTGCGCAATGCGGGGCTGACGGAGCAGGACTACATTAACAACCGCAGCCAGGTTGCGGTTCGC
TCGCAGATCGTCGATGCGCTCACGGACGGCTACACGGCGCCGAAGGTGTTGGTGGAGGCCGTCGACAAGTATCGCCACGA
GACGCGCACGGTCGACTATCTCCTGCTCTCCAACGCAAATATCGACGCGGTCAAGACGCCGGGGGATGATGTACTCGCTC
CGTGGTTCGAAAGCCGCAAGGCGAATTACCGAGCTCCCGAATACCGCAAGTTCAGCTACATCAAACTCGAGCCGGAGGAC
CTCGCCGCGTCCGATTCCGTGACGGAGGAAGAGCTCCGCGCCGATTACGACAAGCGCAAGGAAAGCTTCCGCACGCCGGC
AACGAGAACGGTCGAACAGCTCGCCTTCCCGTCGCGAGAGGCAGCCGACGCCGCGGCCGCAAAGCTTTCCGCCGGAACGT
CCTTCGACGATCTGGTCAAGGCCGAAGGCAAGACGTCGGCGGACGTTCTGCTCGGCGACTTCACCAAGGAGCGCATGCCT
GACGCAAAGATTGCCGATGCAGCCTTTGCCGTTGCTCAGGACGGCGGCACCACGCCCGTGGTCGACGGCCCATTCGGCCC
GGTCATCCTGCGCGTGACCAATATTCGGTCGGAAGCCGTTCGAAGCTATGATGAAGTGAAGGAAGAACTGCGCAAGGAGA
TCGCTCTCGACGCGGCGCGCGATCAGCTCGTCGGTCTTCACGACAAGATCGAAGACGAACGTGCCGGCGGCGTGACCGTC
AAGGAGATTGCCGAACAGCTGAAGCTCAAGCTTGTCACTGTCGTTGCGGTAGACGCTTCCGGCAAGGATCAGAACGGCGA
TGATGTGAAGGACCTGCCGGAACCGCGGGCTCTTCTCCAGGAAGTCTTCAAGGCCGACGTGGGCACAGATACGCTCTCGG
TCAATATCGGGCGCGACGGCTCCGTCTGGTTCGATGTCGAGGAGATCATCCCGGGCCGCGACCGGACTCTCGACGAGGTG
CGCGACGAAGTGGCGGCCGACTGGACCGCGGAGCAGCAGCGTGCGGCGCTTGCGGCAAAGGCGAAGGAACTCAAGGAGCG
CGTGGAAAAGGGCGCCAAGCTCGCCGATATCGCGAGCGAACTTGGCCTCGTGGTCGAGACCAAGACCGGGCTGACCCGCT
CGACGAACGATGCGACGCTCAGTCCTGCTGCGGTGATCGCGGCCTTCGGAGGCGCGAACGGCCACGTTGCCAATGCTCCG
GGGATTGGCGGCGACGGCCAGGTGCTCATGCAGGTCACGGCAGTCGAGGAGAAAGCGCCTGCCGACGCCCTCGACAATGA
CAGCCGTCAGATCGAAGCGATTGCGCGGGCGAGCGGCGACGACATCCTGGATCAGATGGTCTCGACACTGCAAACCGCCT
ATGGCGTCTCGATCAACCAGACGCTTGCCGAAACGGCGCTGGCGCAACGGTGA

Upstream 100 bases:

>100_bases
AATTAGCACCGAACCGCCCTTCAATTCCTCTCTGGTTTGTTCTAAGGAACGAATTCATTCGGCGTCACGCCAGCGTATCC
CAACGAGGTTTTCTGCCCAC

Downstream 100 bases:

>100_bases
CGACGGAGAAGTGAATTCATGAGTGATTTGAAACCGTTCGTCGCCAAAGTCGCAGCGCGCGAGGCACTTAGCCGCGACGA
TGCACGCGCGGCCTTCGAGA

Product: putative peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MLDSLRNAAQTRVVKALLALLILSFMVWGGQTLMVPNTPNAVVTVGDIKVSPSDFRLAYERQVALLSRQLGTPLTRQQAQ
AFGVENQVYAQLVAGAALDQLATDMNLGLSEDRLARLIGEDPAFHGVNGQFDRLTFSSVLRNAGLTEQDYINNRSQVAVR
SQIVDALTDGYTAPKVLVEAVDKYRHETRTVDYLLLSNANIDAVKTPGDDVLAPWFESRKANYRAPEYRKFSYIKLEPED
LAASDSVTEEELRADYDKRKESFRTPATRTVEQLAFPSREAADAAAAKLSAGTSFDDLVKAEGKTSADVLLGDFTKERMP
DAKIADAAFAVAQDGGTTPVVDGPFGPVILRVTNIRSEAVRSYDEVKEELRKEIALDAARDQLVGLHDKIEDERAGGVTV
KEIAEQLKLKLVTVVAVDASGKDQNGDDVKDLPEPRALLQEVFKADVGTDTLSVNIGRDGSVWFDVEEIIPGRDRTLDEV
RDEVAADWTAEQQRAALAAKAKELKERVEKGAKLADIASELGLVVETKTGLTRSTNDATLSPAAVIAAFGGANGHVANAP
GIGGDGQVLMQVTAVEEKAPADALDNDSRQIEAIARASGDDILDQMVSTLQTAYGVSINQTLAETALAQR

Sequences:

>Translated_630_residues
MLDSLRNAAQTRVVKALLALLILSFMVWGGQTLMVPNTPNAVVTVGDIKVSPSDFRLAYERQVALLSRQLGTPLTRQQAQ
AFGVENQVYAQLVAGAALDQLATDMNLGLSEDRLARLIGEDPAFHGVNGQFDRLTFSSVLRNAGLTEQDYINNRSQVAVR
SQIVDALTDGYTAPKVLVEAVDKYRHETRTVDYLLLSNANIDAVKTPGDDVLAPWFESRKANYRAPEYRKFSYIKLEPED
LAASDSVTEEELRADYDKRKESFRTPATRTVEQLAFPSREAADAAAAKLSAGTSFDDLVKAEGKTSADVLLGDFTKERMP
DAKIADAAFAVAQDGGTTPVVDGPFGPVILRVTNIRSEAVRSYDEVKEELRKEIALDAARDQLVGLHDKIEDERAGGVTV
KEIAEQLKLKLVTVVAVDASGKDQNGDDVKDLPEPRALLQEVFKADVGTDTLSVNIGRDGSVWFDVEEIIPGRDRTLDEV
RDEVAADWTAEQQRAALAAKAKELKERVEKGAKLADIASELGLVVETKTGLTRSTNDATLSPAAVIAAFGGANGHVANAP
GIGGDGQVLMQVTAVEEKAPADALDNDSRQIEAIARASGDDILDQMVSTLQTAYGVSINQTLAETALAQR
>Mature_630_residues
MLDSLRNAAQTRVVKALLALLILSFMVWGGQTLMVPNTPNAVVTVGDIKVSPSDFRLAYERQVALLSRQLGTPLTRQQAQ
AFGVENQVYAQLVAGAALDQLATDMNLGLSEDRLARLIGEDPAFHGVNGQFDRLTFSSVLRNAGLTEQDYINNRSQVAVR
SQIVDALTDGYTAPKVLVEAVDKYRHETRTVDYLLLSNANIDAVKTPGDDVLAPWFESRKANYRAPEYRKFSYIKLEPED
LAASDSVTEEELRADYDKRKESFRTPATRTVEQLAFPSREAADAAAAKLSAGTSFDDLVKAEGKTSADVLLGDFTKERMP
DAKIADAAFAVAQDGGTTPVVDGPFGPVILRVTNIRSEAVRSYDEVKEELRKEIALDAARDQLVGLHDKIEDERAGGVTV
KEIAEQLKLKLVTVVAVDASGKDQNGDDVKDLPEPRALLQEVFKADVGTDTLSVNIGRDGSVWFDVEEIIPGRDRTLDEV
RDEVAADWTAEQQRAALAAKAKELKERVEKGAKLADIASELGLVVETKTGLTRSTNDATLSPAAVIAAFGGANGHVANAP
GIGGDGQVLMQVTAVEEKAPADALDNDSRQIEAIARASGDDILDQMVSTLQTAYGVSINQTLAETALAQR

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=409, Percent_Identity=25.9168704156479, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68035; Mature: 68035

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSLRNAAQTRVVKALLALLILSFMVWGGQTLMVPNTPNAVVTVGDIKVSPSDFRLAYE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECEEECCHHHHHHHH
RQVALLSRQLGTPLTRQQAQAFGVENQVYAQLVAGAALDQLATDMNLGLSEDRLARLIGE
HHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
DPAFHGVNGQFDRLTFSSVLRNAGLTEQDYINNRSQVAVRSQIVDALTDGYTAPKVLVEA
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
VDKYRHETRTVDYLLLSNANIDAVKTPGDDVLAPWFESRKANYRAPEYRKFSYIKLEPED
HHHHHHHHHHEEEEEEECCCCCEEECCCCCCCCCHHHHCCCCCCCCCCCCEEEEEECHHH
LAASDSVTEEELRADYDKRKESFRTPATRTVEQLAFPSREAADAAAAKLSAGTSFDDLVK
HCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHH
AEGKTSADVLLGDFTKERMPDAKIADAAFAVAQDGGTTPVVDGPFGPVILRVTNIRSEAV
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHH
RSYDEVKEELRKEIALDAARDQLVGLHDKIEDERAGGVTVKEIAEQLKLKLVTVVAVDAS
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHEEEEEEEEECC
GKDQNGDDVKDLPEPRALLQEVFKADVGTDTLSVNIGRDGSVWFDVEEIIPGRDRTLDEV
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEHHHHCCCCCCCHHHH
RDEVAADWTAEQQRAALAAKAKELKERVEKGAKLADIASELGLVVETKTGLTRSTNDATL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCCCCCCCCC
SPAAVIAAFGGANGHVANAPGIGGDGQVLMQVTAVEEKAPADALDNDSRQIEAIARASGD
CHHHHHHEECCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCHHHHHHHHHCCCH
DILDQMVSTLQTAYGVSINQTLAETALAQR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLDSLRNAAQTRVVKALLALLILSFMVWGGQTLMVPNTPNAVVTVGDIKVSPSDFRLAYE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECEEECCHHHHHHHH
RQVALLSRQLGTPLTRQQAQAFGVENQVYAQLVAGAALDQLATDMNLGLSEDRLARLIGE
HHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
DPAFHGVNGQFDRLTFSSVLRNAGLTEQDYINNRSQVAVRSQIVDALTDGYTAPKVLVEA
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
VDKYRHETRTVDYLLLSNANIDAVKTPGDDVLAPWFESRKANYRAPEYRKFSYIKLEPED
HHHHHHHHHHEEEEEEECCCCCEEECCCCCCCCCHHHHCCCCCCCCCCCCEEEEEECHHH
LAASDSVTEEELRADYDKRKESFRTPATRTVEQLAFPSREAADAAAAKLSAGTSFDDLVK
HCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHH
AEGKTSADVLLGDFTKERMPDAKIADAAFAVAQDGGTTPVVDGPFGPVILRVTNIRSEAV
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHH
RSYDEVKEELRKEIALDAARDQLVGLHDKIEDERAGGVTVKEIAEQLKLKLVTVVAVDAS
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHEEEEEEEEECC
GKDQNGDDVKDLPEPRALLQEVFKADVGTDTLSVNIGRDGSVWFDVEEIIPGRDRTLDEV
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEHHHHCCCCCCCHHHH
RDEVAADWTAEQQRAALAAKAKELKERVEKGAKLADIASELGLVVETKTGLTRSTNDATL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCCCCCCCCC
SPAAVIAAFGGANGHVANAPGIGGDGQVLMQVTAVEEKAPADALDNDSRQIEAIARASGD
CHHHHHHEECCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCHHHHHHHHHCCCH
DILDQMVSTLQTAYGVSINQTLAETALAQR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]