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The map label for this gene is trkG [H]

Identifier: 150396588

GI number: 150396588

Start: 1453934

End: 1455388

Strand: Direct

Name: trkG [H]

Synonym: Smed_1374

Alternate gene names: 150396588

Gene position: 1453934-1455388 (Clockwise)

Preceding gene: 150396585

Following gene: 150396589

Centisome position: 38.44

GC content: 58.21

Gene sequence:

>1455_bases
TTGAACGCGAATCTGATCCGGCACGCTGTCCATCTCGCTGCGATTCTGGGGCTTTATCTCTCCGGCGCGATGCTTATTCC
GGCCTTCGTCGATCTTTATTACGGCCATCCGGACTGGCAGGTTTTTGCCGTGACGGCTTTCATGACCGGCGCGATTTCGT
CAACGACTTTCATGGCGACACGCTCAGGTCCACCGCCATTCTCGAAGAAGTTCGGCTTCCTGGTGGTCAATGTCCTGTGG
CTCGTTTTCTCGATCGTCGGCGCCATTCCACTTTGGCTATCCTCGGTCAATCTCGATTTTGCCCAGGCCTTCTTCGAGTC
CGTATCGGCGGTGACGACGACCGGGTCGACCGTCATCGTCGGCCTCGATGACGCCCCGCCGGGTCTTCTTCTTTGGCGCT
CGCTTCTCAGTTGGCTGGGCGGGATCGGTATCGTCGTTCTCGGCCTCTTCATCATCCCCTACTTGCGCGTCGGCGGCATG
TCCTTTTTCAAGATGGAATCATCCGACACGGGCGACAAACCCTTTGCCCGGCTGGCAAGCTTCGGCCGCGCCTTTCTCGT
CATCTATGTATCGATCACCCTGCTTTGCGCGATCAGTTATGGCGTGCTCGGAATGAGCCGGTTCGACGCGGTCAACCATG
CCATGACGACTGTCGCCACGGGCGGCTTCTCGACGCACGACGCTTCGTTCGGCTATTTCGCGAGCATCCCGCTGTTCTGG
GCCAGCACCTTCTTCATGGCGCTTTGCAGCCTCCCCTTCTCCATCCTGATCGTGCTCTTCGTTCGCGGGCGCCTGGATGC
GCTTCGCGACCCTCAAATCATCGTTTTTCTGGGCTACCTCACGGCGTTCTCGGTTGCGGTCGCGACCTATCACAGGCTTG
CAAACGGCGTCGAATTCCATCTGGCGCTGACGCATGCCTTCTTCAATGTGACATCGCTTCTTTCGACCACCGGTTATGCC
AGCGAGGACTATAGCCTGTGGGGGCCCTTCGTGGTCATGGTCGCCTTCATCTGCACCTTTATCGGCGGGTGCTCCGGCTC
CACTGCCGGCGGCATGAAGGCATATCGATTCGTCGTGCTCTTCAACGCCATTCGGTCGGCCCTGAACAAACTCGTATACC
CGAACGCGATCTATGCGGTCCGCTACGGTAAAAATACGGTCGACGCGGACGTGCAACGGGCGATTCTTCTGTTTTTCATT
ACCTATATTCTGCTCTGGGTTTTCGGCAGCCTGGTCATGGGTGCTCTCGGCTATGACTTCATCACGGCCGTATCGTCCGT
AATCACATGCCTCTCCAACGTAGGTCCCGGCCTTGGGAGTCTCGTCGGCCCCGCGGGGAATTTCGCGACCTTCGAAGACG
CCGAGCTTTATCTGCTGTCTCTGCTGATGCTGCTCGGCCGTCTTGAAGTCTTGACTGTGCTCGTCGTGCTCACACCGGTC
TTCTGGCGGCAGTAA

Upstream 100 bases:

>100_bases
GAAACCATCGATTTGACACGAATCGGTTGGCAACGGCACTATCGCCGCCGCTCCGGGCGATCGCCGGCCATCGACAACCG
CTTGCAGGATATCAAGAGCT

Downstream 100 bases:

>100_bases
CGGCCGCTTCGCTGCGCTTGCTTGACTTGGTGTGCCAAATGCCGAAAGCTTACAAAAATCGGGCATTCTGGGAAGCACGA
TGCCGAGACACCTGCTCCTG

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MNANLIRHAVHLAAILGLYLSGAMLIPAFVDLYYGHPDWQVFAVTAFMTGAISSTTFMATRSGPPPFSKKFGFLVVNVLW
LVFSIVGAIPLWLSSVNLDFAQAFFESVSAVTTTGSTVIVGLDDAPPGLLLWRSLLSWLGGIGIVVLGLFIIPYLRVGGM
SFFKMESSDTGDKPFARLASFGRAFLVIYVSITLLCAISYGVLGMSRFDAVNHAMTTVATGGFSTHDASFGYFASIPLFW
ASTFFMALCSLPFSILIVLFVRGRLDALRDPQIIVFLGYLTAFSVAVATYHRLANGVEFHLALTHAFFNVTSLLSTTGYA
SEDYSLWGPFVVMVAFICTFIGGCSGSTAGGMKAYRFVVLFNAIRSALNKLVYPNAIYAVRYGKNTVDADVQRAILLFFI
TYILLWVFGSLVMGALGYDFITAVSSVITCLSNVGPGLGSLVGPAGNFATFEDAELYLLSLLMLLGRLEVLTVLVVLTPV
FWRQ

Sequences:

>Translated_484_residues
MNANLIRHAVHLAAILGLYLSGAMLIPAFVDLYYGHPDWQVFAVTAFMTGAISSTTFMATRSGPPPFSKKFGFLVVNVLW
LVFSIVGAIPLWLSSVNLDFAQAFFESVSAVTTTGSTVIVGLDDAPPGLLLWRSLLSWLGGIGIVVLGLFIIPYLRVGGM
SFFKMESSDTGDKPFARLASFGRAFLVIYVSITLLCAISYGVLGMSRFDAVNHAMTTVATGGFSTHDASFGYFASIPLFW
ASTFFMALCSLPFSILIVLFVRGRLDALRDPQIIVFLGYLTAFSVAVATYHRLANGVEFHLALTHAFFNVTSLLSTTGYA
SEDYSLWGPFVVMVAFICTFIGGCSGSTAGGMKAYRFVVLFNAIRSALNKLVYPNAIYAVRYGKNTVDADVQRAILLFFI
TYILLWVFGSLVMGALGYDFITAVSSVITCLSNVGPGLGSLVGPAGNFATFEDAELYLLSLLMLLGRLEVLTVLVVLTPV
FWRQ
>Mature_484_residues
MNANLIRHAVHLAAILGLYLSGAMLIPAFVDLYYGHPDWQVFAVTAFMTGAISSTTFMATRSGPPPFSKKFGFLVVNVLW
LVFSIVGAIPLWLSSVNLDFAQAFFESVSAVTTTGSTVIVGLDDAPPGLLLWRSLLSWLGGIGIVVLGLFIIPYLRVGGM
SFFKMESSDTGDKPFARLASFGRAFLVIYVSITLLCAISYGVLGMSRFDAVNHAMTTVATGGFSTHDASFGYFASIPLFW
ASTFFMALCSLPFSILIVLFVRGRLDALRDPQIIVFLGYLTAFSVAVATYHRLANGVEFHLALTHAFFNVTSLLSTTGYA
SEDYSLWGPFVVMVAFICTFIGGCSGSTAGGMKAYRFVVLFNAIRSALNKLVYPNAIYAVRYGKNTVDADVQRAILLFFI
TYILLWVFGSLVMGALGYDFITAVSSVITCLSNVGPGLGSLVGPAGNFATFEDAELYLLSLLMLLGRLEVLTVLVVLTPV
FWRQ

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=490, Percent_Identity=33.469387755102, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI48994987, Length=487, Percent_Identity=36.1396303901437, Blast_Score=254, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52425; Mature: 52425

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANLIRHAVHLAAILGLYLSGAMLIPAFVDLYYGHPDWQVFAVTAFMTGAISSTTFMAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEE
RSGPPPFSKKFGFLVVNVLWLVFSIVGAIPLWLSSVNLDFAQAFFESVSAVTTTGSTVIV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCEEEE
GLDDAPPGLLLWRSLLSWLGGIGIVVLGLFIIPYLRVGGMSFFKMESSDTGDKPFARLAS
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
FGRAFLVIYVSITLLCAISYGVLGMSRFDAVNHAMTTVATGGFSTHDASFGYFASIPLFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ASTFFMALCSLPFSILIVLFVRGRLDALRDPQIIVFLGYLTAFSVAVATYHRLANGVEFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHH
LALTHAFFNVTSLLSTTGYASEDYSLWGPFVVMVAFICTFIGGCSGSTAGGMKAYRFVVL
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
FNAIRSALNKLVYPNAIYAVRYGKNTVDADVQRAILLFFITYILLWVFGSLVMGALGYDF
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITAVSSVITCLSNVGPGLGSLVGPAGNFATFEDAELYLLSLLMLLGRLEVLTVLVVLTPV
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWRQ
HHCC
>Mature Secondary Structure
MNANLIRHAVHLAAILGLYLSGAMLIPAFVDLYYGHPDWQVFAVTAFMTGAISSTTFMAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEE
RSGPPPFSKKFGFLVVNVLWLVFSIVGAIPLWLSSVNLDFAQAFFESVSAVTTTGSTVIV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCEEEE
GLDDAPPGLLLWRSLLSWLGGIGIVVLGLFIIPYLRVGGMSFFKMESSDTGDKPFARLAS
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
FGRAFLVIYVSITLLCAISYGVLGMSRFDAVNHAMTTVATGGFSTHDASFGYFASIPLFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ASTFFMALCSLPFSILIVLFVRGRLDALRDPQIIVFLGYLTAFSVAVATYHRLANGVEFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHH
LALTHAFFNVTSLLSTTGYASEDYSLWGPFVVMVAFICTFIGGCSGSTAGGMKAYRFVVL
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
FNAIRSALNKLVYPNAIYAVRYGKNTVDADVQRAILLFFITYILLWVFGSLVMGALGYDF
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITAVSSVITCLSNVGPGLGSLVGPAGNFATFEDAELYLLSLLMLLGRLEVLTVLVVLTPV
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWRQ
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]