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The map label for this gene is coaD [H]

Identifier: 150396482

GI number: 150396482

Start: 1358823

End: 1359368

Strand: Direct

Name: coaD [H]

Synonym: Smed_1264

Alternate gene names: 150396482

Gene position: 1358823-1359368 (Clockwise)

Preceding gene: 150396481

Following gene: 150396483

Centisome position: 35.93

GC content: 60.44

Gene sequence:

>546_bases
TTGCGGTTCGGCGCCGTCCATGACAAAAGGCTTCACCAAACGGAAACTGGCGCGATGACCACGGCTTTCTATCCCGGCTC
CTTCGATCCGATCACCAACGGGCATCTCGATGTACTCGTACAGGCATTGAACGTCGCAGCGAAGGTCATCGTCGCGATAG
GAGCCCATCCCGGCAAGGCGCCGCTTTTCTCCTTCGATGAAAGGGCGGACCTCATTCGTGCGGCCCTCGTGGAAACGCTA
CCGGAGAGGGCAGTGGACATTTCCGTCGTATCCTTCGACAATCTGGTGGTCGATGCTGCGCGAAAGCATGGCGCAAGGCT
GCTCGTTCGAGGGCTTCGTGACGGAACCGACCTTGACTACGAAATGCAGATGGCGGGCATGAACCGGCAGATGGCTCCCG
ACATTCAGACCCTCTTTCTGCCGGCGGGTACTGCCTCCCGGCCCATTACGGCCACATTGGTTCGGCAGATCGCGGCCATG
GGCGGTGACGTCAGCGCTTTCGTCCCCGGCGCGGTTCATCAGGCGCTTCAGGCCAAGCGCAAGTAA

Upstream 100 bases:

>100_bases
CCGCTTGCCGCGTAAAACCTTCTTGAACGTTGCGTTCATCTAGCATTCAGCCCTTTGCCGCCGCTGTTTCCCAAGGAACA
AGAGCAGGATAGTACAACCC

Downstream 100 bases:

>100_bases
GCTTACATCACGCAAGGAGTTCCAATGAAGATCCTCCAATTCGCTGTTGCCGGAGCCTTGGCGCTCGCCACCTTCACGGG
AGGCGCCTTCTTTGCGGGAG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MRFGAVHDKRLHQTETGAMTTAFYPGSFDPITNGHLDVLVQALNVAAKVIVAIGAHPGKAPLFSFDERADLIRAALVETL
PERAVDISVVSFDNLVVDAARKHGARLLVRGLRDGTDLDYEMQMAGMNRQMAPDIQTLFLPAGTASRPITATLVRQIAAM
GGDVSAFVPGAVHQALQAKRK

Sequences:

>Translated_181_residues
MRFGAVHDKRLHQTETGAMTTAFYPGSFDPITNGHLDVLVQALNVAAKVIVAIGAHPGKAPLFSFDERADLIRAALVETL
PERAVDISVVSFDNLVVDAARKHGARLLVRGLRDGTDLDYEMQMAGMNRQMAPDIQTLFLPAGTASRPITATLVRQIAAM
GGDVSAFVPGAVHQALQAKRK
>Mature_181_residues
MRFGAVHDKRLHQTETGAMTTAFYPGSFDPITNGHLDVLVQALNVAAKVIVAIGAHPGKAPLFSFDERADLIRAALVETL
PERAVDISVVSFDNLVVDAARKHGARLLVRGLRDGTDLDYEMQMAGMNRQMAPDIQTLFLPAGTASRPITATLVRQIAAM
GGDVSAFVPGAVHQALQAKRK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=42.4050632911392, Blast_Score=138, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 19427; Mature: 19427

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFGAVHDKRLHQTETGAMTTAFYPGSFDPITNGHLDVLVQALNVAAKVIVAIGAHPGKA
CCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PLFSFDERADLIRAALVETLPERAVDISVVSFDNLVVDAARKHGARLLVRGLRDGTDLDY
CCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHCCHHHHHHHHCCCCCCCE
EMQMAGMNRQMAPDIQTLFLPAGTASRPITATLVRQIAAMGGDVSAFVPGAVHQALQAKR
EEHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCC
K
C
>Mature Secondary Structure
MRFGAVHDKRLHQTETGAMTTAFYPGSFDPITNGHLDVLVQALNVAAKVIVAIGAHPGKA
CCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PLFSFDERADLIRAALVETLPERAVDISVVSFDNLVVDAARKHGARLLVRGLRDGTDLDY
CCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHCCHHHHHHHHCCCCCCCE
EMQMAGMNRQMAPDIQTLFLPAGTASRPITATLVRQIAAMGGDVSAFVPGAVHQALQAKR
EEHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]