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The map label for this gene is fabZ [H]

Identifier: 150396359

GI number: 150396359

Start: 1209657

End: 1210121

Strand: Direct

Name: fabZ [H]

Synonym: Smed_1140

Alternate gene names: 150396359

Gene position: 1209657-1210121 (Clockwise)

Preceding gene: 150396358

Following gene: 150396360

Centisome position: 31.99

GC content: 55.7

Gene sequence:

>465_bases
ATGAATGAAGCTGCAACGGTCCTCGGAACCGCGGACATACAGGAAATCCTGAAGCTTCTTCCCCATCGTTATCCCTTCTT
GCTCGTGGATCGCATCATCGAGATCGATAGCGACAATTCGGCCATCGGGATCAAGAACGTGACGGCCAATGAGCCGCATT
TCACGGGCCACTTCCCCGAGAAGCCGATCATGCCGGGCGTCCTTTTGATCGAAGGCATGGCGCAGACGGCCGGCGCGATC
TGTGCCCGCAAGACGGGGGGCGGAAGCAATCTCGTATATTTCATGACGATCGACAACGCCCGCTTCCGCAAGCCCGTCGT
ACCGGGAGACCGGGTAGAATTTCATGTCGTAAAGCAAAAGCAGCGCGGCAATATCTGGAAGTTTCACTGTGATGCAAAAG
TTGACGGGCAACTCGTCGCCGAAGCTGATATCGGCGCGATGATTGTCAGCAAGGAAGACGTCTGA

Upstream 100 bases:

>100_bases
TACGGCGGTATTCCGGCGCGGCCGATGCGCGACTTTCTCCGCGATGTCGCTGAAATGGCGCTGAGGTCGAGCGAGAGGCA
GAAGAAGAAGGGTGGCAAGG

Downstream 100 bases:

>100_bases
GAATGATAGCATCAAGTGCGAAGATCCATCCGTCCTCGGCGATCGAGGGCGGGGCGGTAATCGGCGAAAACGTTAAGATC
GGCCCGTTCTGCCATATCGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MNEAATVLGTADIQEILKLLPHRYPFLLVDRIIEIDSDNSAIGIKNVTANEPHFTGHFPEKPIMPGVLLIEGMAQTAGAI
CARKTGGGSNLVYFMTIDNARFRKPVVPGDRVEFHVVKQKQRGNIWKFHCDAKVDGQLVAEADIGAMIVSKEDV

Sequences:

>Translated_154_residues
MNEAATVLGTADIQEILKLLPHRYPFLLVDRIIEIDSDNSAIGIKNVTANEPHFTGHFPEKPIMPGVLLIEGMAQTAGAI
CARKTGGGSNLVYFMTIDNARFRKPVVPGDRVEFHVVKQKQRGNIWKFHCDAKVDGQLVAEADIGAMIVSKEDV
>Mature_154_residues
MNEAATVLGTADIQEILKLLPHRYPFLLVDRIIEIDSDNSAIGIKNVTANEPHFTGHFPEKPIMPGVLLIEGMAQTAGAI
CARKTGGGSNLVYFMTIDNARFRKPVVPGDRVEFHVVKQKQRGNIWKFHCDAKVDGQLVAEADIGAMIVSKEDV

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=137, Percent_Identity=48.1751824817518, Blast_Score=137, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16910; Mature: 16910

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAATVLGTADIQEILKLLPHRYPFLLVDRIIEIDSDNSAIGIKNVTANEPHFTGHFPE
CCCCCEEEEHHHHHHHHHHCCCCCCHHEEEEHEEECCCCCEEEEEECCCCCCCCCCCCCC
KPIMPGVLLIEGMAQTAGAICARKTGGGSNLVYFMTIDNARFRKPVVPGDRVEFHVVKQK
CCCCCCEEEEECHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEC
QRGNIWKFHCDAKVDGQLVAEADIGAMIVSKEDV
CCCCEEEEEECCCCCCEEEEECCCCEEEEECCCC
>Mature Secondary Structure
MNEAATVLGTADIQEILKLLPHRYPFLLVDRIIEIDSDNSAIGIKNVTANEPHFTGHFPE
CCCCCEEEEHHHHHHHHHHCCCCCCHHEEEEHEEECCCCCEEEEEECCCCCCCCCCCCCC
KPIMPGVLLIEGMAQTAGAICARKTGGGSNLVYFMTIDNARFRKPVVPGDRVEFHVVKQK
CCCCCCEEEEECHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEC
QRGNIWKFHCDAKVDGQLVAEADIGAMIVSKEDV
CCCCEEEEEECCCCCCEEEEECCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]