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The map label for this gene is yaeL [C]

Identifier: 150396356

GI number: 150396356

Start: 1204850

End: 1205974

Strand: Direct

Name: yaeL [C]

Synonym: Smed_1137

Alternate gene names: 150396356

Gene position: 1204850-1205974 (Clockwise)

Preceding gene: 150396355

Following gene: 150396357

Centisome position: 31.86

GC content: 62.22

Gene sequence:

>1125_bases
ATGAGCCTTCTGCTTGACAATCTTCAGTACACGATCCCCACGTTCCTGTTCCTCCTGACGTTGCTGGTCTTCGTTCACGA
GATGGGACACTACCTGGTGGGCCGCTGGTCGGGCATTCGCATCCTGGCCTTTTCCGTTGGCTTCGGACCCGAACTCTTCG
GCTGGACCGACCGTCACGGCACCCGCTGGAAATTCTGTGCGATCCCGCTCGGCGGCTATGTGAAGTTCTTCGGCGACGAA
GACGCCGCGAGCACGCCCGACTACCGGCGGCTCGAAACGATCGCGCCGGAAGAGCGTGGCCGGACATTCCTGGGCGCAAA
GCTCTGGAAGCGCGCGGCGACTGTCGCGGCCGGGCCGATCGCGAACTTTCTTCTGGCAATTGCGATCTTCGCCGTCCTCT
TTTCCATTTACGGCCGTGCCGTCGCCGATCCCGTCGTCGCTTTCGTCGCGCCGGGCAGTGCCGCGGAAAAGGCAGGGGTC
CTGCCCGGAGACAGGCTGTTGTCGATCGACGGAGAGCCGATCGCTACCTTTGACGACGTGCGCCGATATGTGAGCGTCCG
CCCCGAACTGCCGATCACCGTTCGAATCGAGCGCGAGGGCGCTGCGATCGACGTGCCGATGGTGCCGCAGCGCACCGAAT
CCGTCGATCCCCTTGGCAATAAAATGGAAGAGGGCAAGATCGGCATCGGCACGAACCAGGAGGCCGGCAATTTCCGGGTC
GAGACCTACGGACCTGTGGAGGCCGTGGGACAAGGGGCACTGCAGAGCTGGCGAATCGTAACCGGCACGCTCGACTATCT
CTCGAATCTCTTTGTCGGCCGCATGAGCGCCGACCAGGTCGGCGGACCGATTCGTATCGCGCAGATGTCCGGCCAGATGG
CGAAGCTCGGCATTGCCGAGGTGCTGAATTTCGCGGCCGTGCTTTCGGTTTCCATTGGATTGCTTAATCTCATGCCCGTG
CCGGTGCTTGATGGCGGCCACCTGATGTTCTATGCCGTCGAAGCGTTGCGCGGCAGGCCGGTGGGTCCCGCCGCCCAGGA
TCTCGCATTTCGCATCGGCTTTGCCATGGTGCTCATGCTGACGGTTTTTGCGGCCTGGAACGATATCAACTGGCTCTTCG
GATAG

Upstream 100 bases:

>100_bases
CGAAACGGGACTATCATGTGGCCATGCGAACGATGGCTGCGCGACCTCTACCTTGCAAATTGAACAGGCGGACGTGGCAG
CGGACGCGTTAGGAATGACT

Downstream 100 bases:

>100_bases
GAGCGGAGCCTTGGGTGGGAGCGGAATAGTTAAGGATTCGGGGAGCAAGTGAGTTTCGCCGGGCTGCTCAGTAACAGTTT
GTTTACGATAATAAGACGCC

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSLLLDNLQYTIPTFLFLLTLLVFVHEMGHYLVGRWSGIRILAFSVGFGPELFGWTDRHGTRWKFCAIPLGGYVKFFGDE
DAASTPDYRRLETIAPEERGRTFLGAKLWKRAATVAAGPIANFLLAIAIFAVLFSIYGRAVADPVVAFVAPGSAAEKAGV
LPGDRLLSIDGEPIATFDDVRRYVSVRPELPITVRIEREGAAIDVPMVPQRTESVDPLGNKMEEGKIGIGTNQEAGNFRV
ETYGPVEAVGQGALQSWRIVTGTLDYLSNLFVGRMSADQVGGPIRIAQMSGQMAKLGIAEVLNFAAVLSVSIGLLNLMPV
PVLDGGHLMFYAVEALRGRPVGPAAQDLAFRIGFAMVLMLTVFAAWNDINWLFG

Sequences:

>Translated_374_residues
MSLLLDNLQYTIPTFLFLLTLLVFVHEMGHYLVGRWSGIRILAFSVGFGPELFGWTDRHGTRWKFCAIPLGGYVKFFGDE
DAASTPDYRRLETIAPEERGRTFLGAKLWKRAATVAAGPIANFLLAIAIFAVLFSIYGRAVADPVVAFVAPGSAAEKAGV
LPGDRLLSIDGEPIATFDDVRRYVSVRPELPITVRIEREGAAIDVPMVPQRTESVDPLGNKMEEGKIGIGTNQEAGNFRV
ETYGPVEAVGQGALQSWRIVTGTLDYLSNLFVGRMSADQVGGPIRIAQMSGQMAKLGIAEVLNFAAVLSVSIGLLNLMPV
PVLDGGHLMFYAVEALRGRPVGPAAQDLAFRIGFAMVLMLTVFAAWNDINWLFG
>Mature_373_residues
SLLLDNLQYTIPTFLFLLTLLVFVHEMGHYLVGRWSGIRILAFSVGFGPELFGWTDRHGTRWKFCAIPLGGYVKFFGDED
AASTPDYRRLETIAPEERGRTFLGAKLWKRAATVAAGPIANFLLAIAIFAVLFSIYGRAVADPVVAFVAPGSAAEKAGVL
PGDRLLSIDGEPIATFDDVRRYVSVRPELPITVRIEREGAAIDVPMVPQRTESVDPLGNKMEEGKIGIGTNQEAGNFRVE
TYGPVEAVGQGALQSWRIVTGTLDYLSNLFVGRMSADQVGGPIRIAQMSGQMAKLGIAEVLNFAAVLSVSIGLLNLMPVP
VLDGGHLMFYAVEALRGRPVGPAAQDLAFRIGFAMVLMLTVFAAWNDINWLFG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=233, Percent_Identity=34.3347639484979, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40622; Mature: 40491

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLLDNLQYTIPTFLFLLTLLVFVHEMGHYLVGRWSGIRILAFSVGFGPELFGWTDRHG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEECCCCHHCCCCCCCC
TRWKFCAIPLGGYVKFFGDEDAASTPDYRRLETIAPEERGRTFLGAKLWKRAATVAAGPI
CEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHH
ANFLLAIAIFAVLFSIYGRAVADPVVAFVAPGSAAEKAGVLPGDRLLSIDGEPIATFDDV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHCCCCCCCCEEEECCCCCCCHHHH
RRYVSVRPELPITVRIEREGAAIDVPMVPQRTESVDPLGNKMEEGKIGIGTNQEAGNFRV
HHHHHCCCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEE
ETYGPVEAVGQGALQSWRIVTGTLDYLSNLFVGRMSADQVGGPIRIAQMSGQMAKLGIAE
EECCCHHHHCCHHHHCCEEEEHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCHHHHHHHH
VLNFAAVLSVSIGLLNLMPVPVLDGGHLMFYAVEALRGRPVGPAAQDLAFRIGFAMVLML
HHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
TVFAAWNDINWLFG
HHHHHHCCCCCCCC
>Mature Secondary Structure 
SLLLDNLQYTIPTFLFLLTLLVFVHEMGHYLVGRWSGIRILAFSVGFGPELFGWTDRHG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEECCCCHHCCCCCCCC
TRWKFCAIPLGGYVKFFGDEDAASTPDYRRLETIAPEERGRTFLGAKLWKRAATVAAGPI
CEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHH
ANFLLAIAIFAVLFSIYGRAVADPVVAFVAPGSAAEKAGVLPGDRLLSIDGEPIATFDDV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHCCCCCCCCEEEECCCCCCCHHHH
RRYVSVRPELPITVRIEREGAAIDVPMVPQRTESVDPLGNKMEEGKIGIGTNQEAGNFRV
HHHHHCCCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEE
ETYGPVEAVGQGALQSWRIVTGTLDYLSNLFVGRMSADQVGGPIRIAQMSGQMAKLGIAE
EECCCHHHHCCHHHHCCEEEEHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCHHHHHHHH
VLNFAAVLSVSIGLLNLMPVPVLDGGHLMFYAVEALRGRPVGPAAQDLAFRIGFAMVLML
HHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
TVFAAWNDINWLFG
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]