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The map label for this gene is frr [H]

Identifier: 150396353

GI number: 150396353

Start: 1202546

End: 1203106

Strand: Direct

Name: frr [H]

Synonym: Smed_1134

Alternate gene names: 150396353

Gene position: 1202546-1203106 (Clockwise)

Preceding gene: 150396352

Following gene: 150396354

Centisome position: 31.8

GC content: 58.65

Gene sequence:

>561_bases
ATGAGTGAAGGTGTGGATCTGAAGGAACTCAAGCGTCGCATGGACGGCGCGATTTCCGCTTTCAAGCACGACATCGCATC
TCTTCGGACCGGTCGCGCTTCGGCGAACGTTCTCGATCCGGTGACCGTCGAAGCCTACGGTTCGCGCATGCCGCTGAACC
AGGTGGCAAACATCACCGTTCCGGAAGCGCGGATGCTTTCGGTTTCGGTCTGGGACAAGTCCATGGTCGGCGCCGTGGAG
CGGGCGATACGCGAGTCAAATCTCGGGCTCAACCCGATCGTCGACGGGCAGAACCTGCGCATTCCGCTGCCCGAGTTGAA
CGAGGAGCGCCGCAAGTCTCTGGTCAAGGTCGCACACGACTACGCCGAGAAAAGCAAGGTCGCCGTTCGCCACGTTCGCC
GTGACGGTATGGACGATCTGAAAAAAGCTGAAAAGGACGGCGAAATCGGCCAGGACGAGAGCCGTGCTCAGTCCGAGCGT
GTCCAAAAAATGACCGATGACGTGATTTCCGAAATCGACCGCTTGCTCGCGGACAAGGAAAAGGAAATCATGCAGGTCTG
A

Upstream 100 bases:

>100_bases
GGAGATATTGACGGGTGGCGGTCGTGCCACCATCGTGACCGATAGTTGACTAGCTGCTGGGGGCCCGCAAGGCCGCTGAA
AATTACGGGAGTCTCGAACC

Downstream 100 bases:

>100_bases
CCTGCGGATAGGTGAGTCTTATTGTCCGGACAGCCCATGCAAGAATTCAATCCCGCAAACGTGCCGGCGCACGTCGCCAT
CATCATGGACGGCAACGGTC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSEGVDLKELKRRMDGAISAFKHDIASLRTGRASANVLDPVTVEAYGSRMPLNQVANITVPEARMLSVSVWDKSMVGAVE
RAIRESNLGLNPIVDGQNLRIPLPELNEERRKSLVKVAHDYAEKSKVAVRHVRRDGMDDLKKAEKDGEIGQDESRAQSER
VQKMTDDVISEIDRLLADKEKEIMQV

Sequences:

>Translated_186_residues
MSEGVDLKELKRRMDGAISAFKHDIASLRTGRASANVLDPVTVEAYGSRMPLNQVANITVPEARMLSVSVWDKSMVGAVE
RAIRESNLGLNPIVDGQNLRIPLPELNEERRKSLVKVAHDYAEKSKVAVRHVRRDGMDDLKKAEKDGEIGQDESRAQSER
VQKMTDDVISEIDRLLADKEKEIMQV
>Mature_185_residues
SEGVDLKELKRRMDGAISAFKHDIASLRTGRASANVLDPVTVEAYGSRMPLNQVANITVPEARMLSVSVWDKSMVGAVER
AIRESNLGLNPIVDGQNLRIPLPELNEERRKSLVKVAHDYAEKSKVAVRHVRRDGMDDLKKAEKDGEIGQDESRAQSERV
QKMTDDVISEIDRLLADKEKEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=182, Percent_Identity=32.967032967033, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI291042689, Length=185, Percent_Identity=32.4324324324324, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI1786368, Length=179, Percent_Identity=49.7206703910614, Blast_Score=175, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24661488, Length=185, Percent_Identity=28.1081081081081, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20819; Mature: 20688

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGVDLKELKRRMDGAISAFKHDIASLRTGRASANVLDPVTVEAYGSRMPLNQVANITV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHCCCCC
PEARMLSVSVWDKSMVGAVERAIRESNLGLNPIVDGQNLRIPLPELNEERRKSLVKVAHD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHH
YAEKSKVAVRHVRRDGMDDLKKAEKDGEIGQDESRAQSERVQKMTDDVISEIDRLLADKE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEIMQV
HHHHCC
>Mature Secondary Structure 
SEGVDLKELKRRMDGAISAFKHDIASLRTGRASANVLDPVTVEAYGSRMPLNQVANITV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHCCCCC
PEARMLSVSVWDKSMVGAVERAIRESNLGLNPIVDGQNLRIPLPELNEERRKSLVKVAHD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHH
YAEKSKVAVRHVRRDGMDDLKKAEKDGEIGQDESRAQSERVQKMTDDVISEIDRLLADKE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEIMQV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]