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The map label for this gene is secY [H]

Identifier: 150396227

GI number: 150396227

Start: 1077882

End: 1079222

Strand: Direct

Name: secY [H]

Synonym: Smed_1006

Alternate gene names: 150396227

Gene position: 1077882-1079222 (Clockwise)

Preceding gene: 150396226

Following gene: 150396228

Centisome position: 28.5

GC content: 59.13

Gene sequence:

>1341_bases
ATGGCTTCTGCAGCGGAACAGCTCGCCTCGAACCTGAATTTTTCGACTTTCGCCAAGGCGGAAGATCTGAAGAAGCGGCT
CTGGTTCACCCTTGGTGCGCTTCTGGTCTATCGACTTGGCACCTATATTCCGTTGCCGGGCCTTAATCCGGATGCATTCG
CACAGGCGTTCCAGGGACAGTCGGCGGGCATTCTCGGCCTGTTCAACATGTTCTCGGGCGGCGCAGTCGAGCGCATGGCT
ATCTTCGCGCTCGGCATCATGCCCTATATCTCCGCCTCCATTATCGTGCAGCTCATGACCTCGGTCGTTCCGGCGCTCGA
GCAGCTGAAAAAGGAAGGCGAGCAGGGTCGTAAGGTCATCAATCAGTACACCCGCTACGGCACGGTGCTCCTGGGCGCGA
TGCAGGCCTACGGGATTGCCGTCGGGCTCGAAAGCGGCAGCGGCCTCGTGAACGATCCGGGTTGGTTCTTCCGGATTTCG
ACCGTAATTTCGCTTCTCGGCGGCACGATGTTCCTGATGTGGCTTGGTGAGCAGATCACGTCGCGCGGCATCGGCAACGG
CATTTCACTGATCATCTTTGCCGGTATCGTCGCCGCTCTGCCTTCGGCACTTGCCGGCACGCTTGAGTTGGGCCGCACCG
GAGCGCTGTCGACGCCTCTGATCCTGGCGATCATCGTCATGGTCGTCGCCGTGATTGCGCTGATCGTCTTTGTCGAGCGC
GCGCAGCGCCGCCTGTTGATCCAGTATCCGAAGCGTCAGGTCGGCAACCGGATGTTCCAAGGCGACACGTCGCACCTGCC
GTTGAAGCTCAACACATCCGGCGTGATCCCGGCGATCTTCGCATCGTCGCTGCTCCTGCTGCCCGCTACGCTTGCCGGTT
TCGCCAACAGCGCGACCATGCCGGGTTGGGCGACGACGATCGTCGGCGCGCTGGCGCACGGCCAGCCTCTCTACATGTTT
CTTTACGGTGCGATGATCGCGTTCTTTGCCTTCTTCTATACGGCGATCGTGTTCAATCCGAAGGACACAGCCGACAATCT
AAAGAAGCACGGCGGGTTTATTCCAGGCATTCGCCCAGGTGAACGCACTGCCGAATACATCGACTACGTATTGACGCGTA
TCACCGTCGTCGGCGCAATCTACCTGATCTTCGTCTGCATCCTGCCTGAGATCCTCATCTCGCAGACCGGCGTGCCGTTC
TACCTTGGTGGTACGTCGCTTTTGATTGTTGTCAGCGTGACCCTCGATACGGTAGCACAGATCCAGGGTCACCTCATCGC
TCAGCAATATGAGGGGCTGATCAAGAAGTCGAAGCTGCGCGGAGGAAAGAGGGGACGATGA

Upstream 100 bases:

>100_bases
CGACAATCGCCTCGCGCCAGGTTTTCAACGACGAAAACTGATTCCATCCGGAACGAGCGGGTTTGCCCGCGTTTCCGAGA
CTTGGTACGCGGAGAATTGC

Downstream 100 bases:

>100_bases
GACTGATATTTTTGGGACCGCCGGGCGCTGGCAAGGGAACTCAGGCCAAGCATCTGACGGAGAGATATGGTATTCCGCAG
CTTTCCACGGGGGATATGTT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MASAAEQLASNLNFSTFAKAEDLKKRLWFTLGALLVYRLGTYIPLPGLNPDAFAQAFQGQSAGILGLFNMFSGGAVERMA
IFALGIMPYISASIIVQLMTSVVPALEQLKKEGEQGRKVINQYTRYGTVLLGAMQAYGIAVGLESGSGLVNDPGWFFRIS
TVISLLGGTMFLMWLGEQITSRGIGNGISLIIFAGIVAALPSALAGTLELGRTGALSTPLILAIIVMVVAVIALIVFVER
AQRRLLIQYPKRQVGNRMFQGDTSHLPLKLNTSGVIPAIFASSLLLLPATLAGFANSATMPGWATTIVGALAHGQPLYMF
LYGAMIAFFAFFYTAIVFNPKDTADNLKKHGGFIPGIRPGERTAEYIDYVLTRITVVGAIYLIFVCILPEILISQTGVPF
YLGGTSLLIVVSVTLDTVAQIQGHLIAQQYEGLIKKSKLRGGKRGR

Sequences:

>Translated_446_residues
MASAAEQLASNLNFSTFAKAEDLKKRLWFTLGALLVYRLGTYIPLPGLNPDAFAQAFQGQSAGILGLFNMFSGGAVERMA
IFALGIMPYISASIIVQLMTSVVPALEQLKKEGEQGRKVINQYTRYGTVLLGAMQAYGIAVGLESGSGLVNDPGWFFRIS
TVISLLGGTMFLMWLGEQITSRGIGNGISLIIFAGIVAALPSALAGTLELGRTGALSTPLILAIIVMVVAVIALIVFVER
AQRRLLIQYPKRQVGNRMFQGDTSHLPLKLNTSGVIPAIFASSLLLLPATLAGFANSATMPGWATTIVGALAHGQPLYMF
LYGAMIAFFAFFYTAIVFNPKDTADNLKKHGGFIPGIRPGERTAEYIDYVLTRITVVGAIYLIFVCILPEILISQTGVPF
YLGGTSLLIVVSVTLDTVAQIQGHLIAQQYEGLIKKSKLRGGKRGR
>Mature_445_residues
ASAAEQLASNLNFSTFAKAEDLKKRLWFTLGALLVYRLGTYIPLPGLNPDAFAQAFQGQSAGILGLFNMFSGGAVERMAI
FALGIMPYISASIIVQLMTSVVPALEQLKKEGEQGRKVINQYTRYGTVLLGAMQAYGIAVGLESGSGLVNDPGWFFRIST
VISLLGGTMFLMWLGEQITSRGIGNGISLIIFAGIVAALPSALAGTLELGRTGALSTPLILAIIVMVVAVIALIVFVERA
QRRLLIQYPKRQVGNRMFQGDTSHLPLKLNTSGVIPAIFASSLLLLPATLAGFANSATMPGWATTIVGALAHGQPLYMFL
YGAMIAFFAFFYTAIVFNPKDTADNLKKHGGFIPGIRPGERTAEYIDYVLTRITVVGAIYLIFVCILPEILISQTGVPFY
LGGTSLLIVVSVTLDTVAQIQGHLIAQQYEGLIKKSKLRGGKRGR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=426, Percent_Identity=56.5727699530516, Blast_Score=450, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47863; Mature: 47732

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAAEQLASNLNFSTFAKAEDLKKRLWFTLGALLVYRLGTYIPLPGLNPDAFAQAFQGQ
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
SAGILGLFNMFSGGAVERMAIFALGIMPYISASIIVQLMTSVVPALEQLKKEGEQGRKVI
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQYTRYGTVLLGAMQAYGIAVGLESGSGLVNDPGWFFRISTVISLLGGTMFLMWLGEQIT
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRGIGNGISLIIFAGIVAALPSALAGTLELGRTGALSTPLILAIIVMVVAVIALIVFVER
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AQRRLLIQYPKRQVGNRMFQGDTSHLPLKLNTSGVIPAIFASSLLLLPATLAGFANSATM
HHHHHHHHCCHHHHCCHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PGWATTIVGALAHGQPLYMFLYGAMIAFFAFFYTAIVFNPKDTADNLKKHGGFIPGIRPG
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCC
ERTAEYIDYVLTRITVVGAIYLIFVCILPEILISQTGVPFYLGGTSLLIVVSVTLDTVAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEHHHHHHHHHHHH
IQGHLIAQQYEGLIKKSKLRGGKRGR
HHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ASAAEQLASNLNFSTFAKAEDLKKRLWFTLGALLVYRLGTYIPLPGLNPDAFAQAFQGQ
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
SAGILGLFNMFSGGAVERMAIFALGIMPYISASIIVQLMTSVVPALEQLKKEGEQGRKVI
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQYTRYGTVLLGAMQAYGIAVGLESGSGLVNDPGWFFRISTVISLLGGTMFLMWLGEQIT
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRGIGNGISLIIFAGIVAALPSALAGTLELGRTGALSTPLILAIIVMVVAVIALIVFVER
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AQRRLLIQYPKRQVGNRMFQGDTSHLPLKLNTSGVIPAIFASSLLLLPATLAGFANSATM
HHHHHHHHCCHHHHCCHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PGWATTIVGALAHGQPLYMFLYGAMIAFFAFFYTAIVFNPKDTADNLKKHGGFIPGIRPG
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCC
ERTAEYIDYVLTRITVVGAIYLIFVCILPEILISQTGVPFYLGGTSLLIVVSVTLDTVAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEHHHHHHHHHHHH
IQGHLIAQQYEGLIKKSKLRGGKRGR
HHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]