Click here to switch to the map view.

The map label for this gene is ctaD [H]

Identifier: 150395743

GI number: 150395743

Start: 562711

End: 564399

Strand: Direct

Name: ctaD [H]

Synonym: Smed_0519

Alternate gene names: 150395743

Gene position: 562711-564399 (Clockwise)

Preceding gene: 150395742

Following gene: 150395744

Centisome position: 14.88

GC content: 60.27

Gene sequence:

>1689_bases
ATGGCTGGAACAGCCGTTCATCACGATCAACGCCATGATCATTCCGATCATGGCCACGCGGAACACGCGCACAAGCCGCT
GACATTTTTTCAGCGCTGGTTCCTGTCGACCAACCACAAGGACATCGGAACGCTCTACCTGATCTTCGCGATCATCGCCG
GTATCATCGGCGGAACGCTGTCGGTCTTCATGCGCGCCGAACTGCAGGAGCCGGGCATCCAGATCTTCCACGGTCTGGCG
CAGATGGTCTATGGTTTCGAGGGTGATGCTGCCATCGACGGCGGCAAGCACATGTTCAACGTCTTCACGACAGCGCACGC
CCTGATCATGATCTTCTTCATGGTCATGCCGGCCTTGATCGGTGGTTTCGCCAACTGGATGGTGCCGATCATGATCGGCG
CACCGGACATGGCGTTCCCGCGCATGAACAACATTTCCTTCTGGCTCATCGTGCCGGCATTCCTGCTCGTGCTGCTTTCG
ATGTTCGTCGAAGGTCCTGCAGGCGCCTATGGTGCGGGCGGCGGCTGGACGATCTATCCGCCATTCTCGACATCCGGCAT
GCCCGGGCCGGCAATGGATCTTGCAATTCTCGGCCTGCATATTGCCGGTGCCTCGTCGATCCTCGGTGCGATCAACTTCA
TCACCACCATCCTCAACATGCGCGCTCCGGGCATGACGCTGCACAAGATGCCGCTCTTCGCCTGGTCGGTTCTGATCACC
GCCTTCCTGCTCCTGCTCTCGCTGCCGGTTCTCGCAGGTGCGATCACGATGCTGCTGACGGACCGCAACTTCGGCACAAC
CTTCTTCTCGCCGGAAGGCGGCGGCGACCCGATCCTGTTCCAGCACCTGTTCTGGTTCTTCGGTCACCCGGAAGTGTACA
TCTTGATCCTGCCGGGCTTCGGCATCGTCAGCCACATCATCTCGACCTTCTCGCGCAAGCCGATCTTCGGCTATCTCGGG
ATGGCCTACGCCATGGTCGCTATCGGCGCGGTCGGCTTCATCGTGTGGGCGCACCACATGTACACGGTCGGCATGTCGCT
CCAGACGCAGCGCTACTTCGTCTTCGCGACGATGGTCATCGCGGTTCCGACTGGTGTGAAGATCTTCTCCTGGATTGCGA
CGATGTGGGGCGGCTCGATCCGCTTCTCCACGCCGATGGTCTGGGCGATCGGCTTCATCTTCCTGTTCACGGTCGGCGGC
GTCACCGGTGTTCAGCTCGCCAATGCCGGCCTCGACCGCGCACTGCACGACACCTATTACGTGGTGGCGCACTTCCATTA
CGTGCTCTCGCTCGGCGCCGTTTTCGCGATCTTTGCGGCCTGGTACTACTGGTTCCCCAAGATGACCGGCTACATGTATT
CGGAGTTTCTCGGCAAGCTGCACTTCTGGGTGATGTTCGTCGGCGTGAACCTCATCTTCTTCCCGCAGCACTTCCTCGGC
CTCGCGGGCATGCCGCGCCGATACATTGATTATCCGGACGCCTTTGCAGGCTGGAATATGGTATCGTCCTACGGCTCCTA
CATCGCGGCCGTCGGCGTGCTGATCTTTCTCTACTGTGTCGCCGAAGCTTTCGCGAAGAAGCGCGTTGCAGGGGATAACC
CCTGGGGTGAAGGCGCCAACACGCTGGAATGGCAGCTGTCCTCGCCGCCGCCGTTCCACCAGTGGGAGCAGCTCCCGCGG
ATCAAGTGA

Upstream 100 bases:

>100_bases
GGCGAAGCGAACAAGGCGCTCATGGCGTCCGTCGACGGCGCGGCCAAGGCCGTTGACGTCGCCGAAAACGCCGCACAGTA
ATCGGAAGTGGAGCTTGACC

Downstream 100 bases:

>100_bases
CGGGAAACGAGCAGAAGCCGCCGGTTACGGCGGCTTCTCCCCGCCGGCAAGCCGGCGCGAAGCGGCTTTTCCTGCCGCAT
CAAGTTCAGGGTAAGGACAT

Product: cytochrome c oxidase subunit I type

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MAGTAVHHDQRHDHSDHGHAEHAHKPLTFFQRWFLSTNHKDIGTLYLIFAIIAGIIGGTLSVFMRAELQEPGIQIFHGLA
QMVYGFEGDAAIDGGKHMFNVFTTAHALIMIFFMVMPALIGGFANWMVPIMIGAPDMAFPRMNNISFWLIVPAFLLVLLS
MFVEGPAGAYGAGGGWTIYPPFSTSGMPGPAMDLAILGLHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSVLIT
AFLLLLSLPVLAGAITMLLTDRNFGTTFFSPEGGGDPILFQHLFWFFGHPEVYILILPGFGIVSHIISTFSRKPIFGYLG
MAYAMVAIGAVGFIVWAHHMYTVGMSLQTQRYFVFATMVIAVPTGVKIFSWIATMWGGSIRFSTPMVWAIGFIFLFTVGG
VTGVQLANAGLDRALHDTYYVVAHFHYVLSLGAVFAIFAAWYYWFPKMTGYMYSEFLGKLHFWVMFVGVNLIFFPQHFLG
LAGMPRRYIDYPDAFAGWNMVSSYGSYIAAVGVLIFLYCVAEAFAKKRVAGDNPWGEGANTLEWQLSSPPPFHQWEQLPR
IK

Sequences:

>Translated_562_residues
MAGTAVHHDQRHDHSDHGHAEHAHKPLTFFQRWFLSTNHKDIGTLYLIFAIIAGIIGGTLSVFMRAELQEPGIQIFHGLA
QMVYGFEGDAAIDGGKHMFNVFTTAHALIMIFFMVMPALIGGFANWMVPIMIGAPDMAFPRMNNISFWLIVPAFLLVLLS
MFVEGPAGAYGAGGGWTIYPPFSTSGMPGPAMDLAILGLHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSVLIT
AFLLLLSLPVLAGAITMLLTDRNFGTTFFSPEGGGDPILFQHLFWFFGHPEVYILILPGFGIVSHIISTFSRKPIFGYLG
MAYAMVAIGAVGFIVWAHHMYTVGMSLQTQRYFVFATMVIAVPTGVKIFSWIATMWGGSIRFSTPMVWAIGFIFLFTVGG
VTGVQLANAGLDRALHDTYYVVAHFHYVLSLGAVFAIFAAWYYWFPKMTGYMYSEFLGKLHFWVMFVGVNLIFFPQHFLG
LAGMPRRYIDYPDAFAGWNMVSSYGSYIAAVGVLIFLYCVAEAFAKKRVAGDNPWGEGANTLEWQLSSPPPFHQWEQLPR
IK
>Mature_561_residues
AGTAVHHDQRHDHSDHGHAEHAHKPLTFFQRWFLSTNHKDIGTLYLIFAIIAGIIGGTLSVFMRAELQEPGIQIFHGLAQ
MVYGFEGDAAIDGGKHMFNVFTTAHALIMIFFMVMPALIGGFANWMVPIMIGAPDMAFPRMNNISFWLIVPAFLLVLLSM
FVEGPAGAYGAGGGWTIYPPFSTSGMPGPAMDLAILGLHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSVLITA
FLLLLSLPVLAGAITMLLTDRNFGTTFFSPEGGGDPILFQHLFWFFGHPEVYILILPGFGIVSHIISTFSRKPIFGYLGM
AYAMVAIGAVGFIVWAHHMYTVGMSLQTQRYFVFATMVIAVPTGVKIFSWIATMWGGSIRFSTPMVWAIGFIFLFTVGGV
TGVQLANAGLDRALHDTYYVVAHFHYVLSLGAVFAIFAAWYYWFPKMTGYMYSEFLGKLHFWVMFVGVNLIFFPQHFLGL
AGMPRRYIDYPDAFAGWNMVSSYGSYIAAVGVLIFLYCVAEAFAKKRVAGDNPWGEGANTLEWQLSSPPPFHQWEQLPRI
K

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=536, Percent_Identity=59.7014925373134, Blast_Score=601, Evalue=1e-172,
Organism=Escherichia coli, GI1786634, Length=537, Percent_Identity=41.340782122905, Blast_Score=377, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226519, Length=548, Percent_Identity=54.5620437956204, Blast_Score=589, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6226524, Length=343, Percent_Identity=57.4344023323615, Blast_Score=393, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6226523, Length=268, Percent_Identity=51.865671641791, Blast_Score=251, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 62192; Mature: 62061

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTAVHHDQRHDHSDHGHAEHAHKPLTFFQRWFLSTNHKDIGTLYLIFAIIAGIIGGTL
CCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SVFMRAELQEPGIQIFHGLAQMVYGFEGDAAIDGGKHMFNVFTTAHALIMIFFMVMPALI
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GGFANWMVPIMIGAPDMAFPRMNNISFWLIVPAFLLVLLSMFVEGPAGAYGAGGGWTIYP
HHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEC
PFSTSGMPGPAMDLAILGLHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSVLIT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AFLLLLSLPVLAGAITMLLTDRNFGTTFFSPEGGGDPILFQHLFWFFGHPEVYILILPGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCH
GIVSHIISTFSRKPIFGYLGMAYAMVAIGAVGFIVWAHHMYTVGMSLQTQRYFVFATMVI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AVPTGVKIFSWIATMWGGSIRFSTPMVWAIGFIFLFTVGGVTGVQLANAGLDRALHDTYY
HHCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VVAHFHYVLSLGAVFAIFAAWYYWFPKMTGYMYSEFLGKLHFWVMFVGVNLIFFPQHFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LAGMPRRYIDYPDAFAGWNMVSSYGSYIAAVGVLIFLYCVAEAFAKKRVAGDNPWGEGAN
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TLEWQLSSPPPFHQWEQLPRIK
EEEEEECCCCCCHHHHCCCCCC
>Mature Secondary Structure 
AGTAVHHDQRHDHSDHGHAEHAHKPLTFFQRWFLSTNHKDIGTLYLIFAIIAGIIGGTL
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SVFMRAELQEPGIQIFHGLAQMVYGFEGDAAIDGGKHMFNVFTTAHALIMIFFMVMPALI
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GGFANWMVPIMIGAPDMAFPRMNNISFWLIVPAFLLVLLSMFVEGPAGAYGAGGGWTIYP
HHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEC
PFSTSGMPGPAMDLAILGLHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSVLIT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AFLLLLSLPVLAGAITMLLTDRNFGTTFFSPEGGGDPILFQHLFWFFGHPEVYILILPGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCH
GIVSHIISTFSRKPIFGYLGMAYAMVAIGAVGFIVWAHHMYTVGMSLQTQRYFVFATMVI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AVPTGVKIFSWIATMWGGSIRFSTPMVWAIGFIFLFTVGGVTGVQLANAGLDRALHDTYY
HHCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VVAHFHYVLSLGAVFAIFAAWYYWFPKMTGYMYSEFLGKLHFWVMFVGVNLIFFPQHFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LAGMPRRYIDYPDAFAGWNMVSSYGSYIAAVGVLIFLYCVAEAFAKKRVAGDNPWGEGAN
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TLEWQLSSPPPFHQWEQLPRIK
EEEEEECCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]