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The map label for this gene is atpE [H]

Identifier: 150395673

GI number: 150395673

Start: 486043

End: 486270

Strand: Direct

Name: atpE [H]

Synonym: Smed_0448

Alternate gene names: 150395673

Gene position: 486043-486270 (Clockwise)

Preceding gene: 150395672

Following gene: 150395674

Centisome position: 12.85

GC content: 61.4

Gene sequence:

>228_bases
ATGGAAGCGGAAGCAGCAAAGTACATCGGTGCAGGTCTTGCATGCCTTGGTATGGCCGGCACGGCTCTCGGCCTCGGCAA
CATCTTCGGCAGCTATCTGTCCGGCGCTCTGCGCAACCCGTCGGCTGCGGACGGCCAGTTCGGTCGCCTCGTATTCGGCT
TTGCCGTTACGGAAGCTCTGGGCATCTTCTCGCTGCTCATTGCACTCCTCCTCCTCTTCGCCGTCTGA

Upstream 100 bases:

>100_bases
CCATCCGGGAAGCCACTAAGGAATACAGTCGCTGGTTTCCGGTCGGCTTGCCGCCGGAAGCGCAATCCTAAGCCGCAACA
CCATTTCGAAGGAGTCAATC

Downstream 100 bases:

>100_bases
TATCGGCAGAAGTTCTGGCCGCGGCCCCCGGGGGTCGCGGCCACGCATATTCTTGAGTGCACCTGGAGGTGAGCATGTTT
GTGACCGCGGCCTATGCCCA

Product: F0F1 ATP synthase subunit C

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(0) sector subunit c; F-type ATPase subunit c; F-ATPase subunit c; Lipid-binding protein [H]

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MEAEAAKYIGAGLACLGMAGTALGLGNIFGSYLSGALRNPSAADGQFGRLVFGFAVTEALGIFSLLIALLLLFAV

Sequences:

>Translated_75_residues
MEAEAAKYIGAGLACLGMAGTALGLGNIFGSYLSGALRNPSAADGQFGRLVFGFAVTEALGIFSLLIALLLLFAV
>Mature_75_residues
MEAEAAKYIGAGLACLGMAGTALGLGNIFGSYLSGALRNPSAADGQFGRLVFGFAVTEALGIFSLLIALLLLFAV

Specific function: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits [H]

COG id: COG0636

COG function: function code C; F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase C chain family [H]

Homologues:

Organism=Homo sapiens, GI50593533, Length=71, Percent_Identity=49.2957746478873, Blast_Score=69, Evalue=6e-13,
Organism=Homo sapiens, GI85794840, Length=71, Percent_Identity=49.2957746478873, Blast_Score=69, Evalue=7e-13,
Organism=Homo sapiens, GI50659069, Length=71, Percent_Identity=49.2957746478873, Blast_Score=69, Evalue=8e-13,
Organism=Homo sapiens, GI4885081, Length=71, Percent_Identity=49.2957746478873, Blast_Score=69, Evalue=8e-13,
Organism=Homo sapiens, GI4502301, Length=71, Percent_Identity=49.2957746478873, Blast_Score=69, Evalue=8e-13,
Organism=Homo sapiens, GI50659074, Length=71, Percent_Identity=49.2957746478873, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71996409, Length=72, Percent_Identity=47.2222222222222, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6226533, Length=71, Percent_Identity=45.0704225352113, Blast_Score=66, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24651601, Length=71, Percent_Identity=50.7042253521127, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651603, Length=71, Percent_Identity=50.7042253521127, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651599, Length=71, Percent_Identity=50.7042253521127, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000454
- InterPro:   IPR002379 [H]

Pfam domain/function: PF00137 ATP-synt_C [H]

EC number: 3.6.3.14

Molecular weight: Translated: 7554; Mature: 7554

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAEAAKYIGAGLACLGMAGTALGLGNIFGSYLSGALRNPSAADGQFGRLVFGFAVTEAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
GIFSLLIALLLLFAV
HHHHHHHHHHHHHHC
>Mature Secondary Structure
MEAEAAKYIGAGLACLGMAGTALGLGNIFGSYLSGALRNPSAADGQFGRLVFGFAVTEAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
GIFSLLIALLLLFAV
HHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA