Click here to switch to the map view.

The map label for this gene is kup1

Identifier: 150395669

GI number: 150395669

Start: 481216

End: 483108

Strand: Direct

Name: kup1

Synonym: Smed_0444

Alternate gene names: 150395669

Gene position: 481216-483108 (Clockwise)

Preceding gene: 150395668

Following gene: 150395670

Centisome position: 12.72

GC content: 60.06

Gene sequence:

>1893_bases
ATGTCTCAATTGTCTGCTCCCGGGGCGGAGAACACCCGCCGCCTGCTTGCCATGGCTCTCGGATCCGTAGGCGTCGTCTA
TGGCGATATCGGCACCAGCCCGCTCTACGCTTTTCGCGAAGCCTTGCGACCCGTCTCGCATGACGGTGTGACGGACGTCG
AGATCGTTGGCTTGATCTCGCTGATGATCTGGGCGCTCACGATCATCGTCACCATAAAATACGTGCTTTTCCTGCTGCGG
GCGGACAACCAGGGCGAGGGAGGGACGCTTTCCCTGTTGGCGCTGCTCATGAAGACGGCCAATGGCCACACGGCGATCCT
GTTCTTCATGGGCATTGCCGGCGCGGCGCTCTTCATCGGTGACGCGATGATCACGCCGGCGCTGTCGGTGCTCTCGGCCG
TCGAGGGGCTGAAACTGGTGACGCCCGCCCTTTCGGACTACGTCGTTCCAATCGCGGTCGTAATTCTCCTGTTTCTTTTT
GCCGTTCAGTCGAAGGGGACCGCCGCGGTCTCGAAGTTCTTCGGGCCGATCACCCTCGTGTGGTTTCTGGTGATGGGTGC
TGTCGGCTTCATGCACATTGCCGATGATCTGTCGATTTTCAGAGCCTTCAACCCTTACTATGCCGTCGCTTTCCTTTTCA
ATGAAGGATATGTCGGCATCGTCGTACTCGGCGCCGTCTTTCTGACGGTTACGGGGGCAGAGGCGCTCTACGCCGATCTC
GGCCATTTCGGCCGCAGGCCGATCCAGTGGGCCTGGTTCACCGTCGTCTTCCCCGCGCTCACGCTGAACTACCTGGGGCA
GGGCGCGTTCGTCCTCAAGAACCCCGAAGCGATGTCAGATCCTTTCTTTCTGATGTTTCCCAAATGGGCGCTGCTGCCGG
CCGTCATTCTTGCGACGGCAGCGACGATTATCGCCAGCCAAGCCGTGATCACCGGTGCCTTTTCGCTCACGCGTCAGGCG
ATCCACCTCGGCTTCCTGCCGCGAATGGCGATTTTCCATACATCCGAGACGCATACCGGCCAGATCTACCTGCCCAACGT
CAACACGCTGCTGATGTTCGGCGTCATGGCGCTCGTCTTCATTTTCGGATCGTCCGAGTCCCTCGCGACCGCATACGGCA
TTTCGGTGACTGGCGCGATGGTGGTTACCACCGTCCTGGCCTTCGAATTCCTGCGCATGCGTTGGAACTGGCCTGCCTGG
TGGGCGGCCGGCGTGCTGCTGCCGCTGTTCGCGCTGGAACTCGTCTTCCTGGGCGCGAACATGCTGAAGATCCACGATGG
CGGCTACGTTCCGATCCTGATCGCGGCGACCTTCATCGTCATCATGTGGACCTGGAAGCGCGGCACCGCAATTCTGCACA
CAAAGACCCGCCACATCGACATTCCACTCGAACGCTTCATCAAATCCATCGAGCGCCAGAGCGAGCATGCACCGGTATCG
GTCCCCGGCACGGCGATCTTCCTCACCAGCGATCCGGAATCGACGCCCGCCGCGCTTCTGCACAACATCAAGCACAATCA
CGTTCTGCATCAGCAGAATTTCATCCTGACGATCCGGACCGCAAACACGCCGAAGGTACCCAGGGAAGAGCGGGTAAGCG
CCCGGCGGCTATCGGAGCGTTTCACCCTGATGGAAGTGAGGTTCGGCTTCATGGAGACGCAGAACGTCTCACAGGCTCTT
GGCCTTTTCCGAAAATCCGGCCTGAAGTTCGATATCATGTCGACCTCTTTCTATCTGGGCCGCCGCAAACTCGTGCCGGA
CGCCCAGTCCGGCATGCCGCATTGGCAGGACCGCCTGTTCATCGCCCTTGCAAACGCCGCAATCGACCCCTCGGACTATT
TCCGCCTGCCGACGAACCGGGTGGTTGAACTGGGCTCTCACGTCATCATCTGA

Upstream 100 bases:

>100_bases
GTTCGGCTATCCGTGGGCGCTTGCGGTCATGGTCCTTTCGGCCGTGATTCCGTTTTTCTTCTTCCGCTGGAAAGGCTGGC
TCTAGGAGCTTGTTGGGCCC

Downstream 100 bases:

>100_bases
CGATCCTCGAAAAGTGGCCCCCACCGGCGTTTCGGCTTGTTCCGGCGTCCGGCATTAACCAAACATCAAGGTTAATCCCG
CATTTTCAAAGCCGAACGAA

Product: K potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MSQLSAPGAENTRRLLAMALGSVGVVYGDIGTSPLYAFREALRPVSHDGVTDVEIVGLISLMIWALTIIVTIKYVLFLLR
ADNQGEGGTLSLLALLMKTANGHTAILFFMGIAGAALFIGDAMITPALSVLSAVEGLKLVTPALSDYVVPIAVVILLFLF
AVQSKGTAAVSKFFGPITLVWFLVMGAVGFMHIADDLSIFRAFNPYYAVAFLFNEGYVGIVVLGAVFLTVTGAEALYADL
GHFGRRPIQWAWFTVVFPALTLNYLGQGAFVLKNPEAMSDPFFLMFPKWALLPAVILATAATIIASQAVITGAFSLTRQA
IHLGFLPRMAIFHTSETHTGQIYLPNVNTLLMFGVMALVFIFGSSESLATAYGISVTGAMVVTTVLAFEFLRMRWNWPAW
WAAGVLLPLFALELVFLGANMLKIHDGGYVPILIAATFIVIMWTWKRGTAILHTKTRHIDIPLERFIKSIERQSEHAPVS
VPGTAIFLTSDPESTPAALLHNIKHNHVLHQQNFILTIRTANTPKVPREERVSARRLSERFTLMEVRFGFMETQNVSQAL
GLFRKSGLKFDIMSTSFYLGRRKLVPDAQSGMPHWQDRLFIALANAAIDPSDYFRLPTNRVVELGSHVII

Sequences:

>Translated_630_residues
MSQLSAPGAENTRRLLAMALGSVGVVYGDIGTSPLYAFREALRPVSHDGVTDVEIVGLISLMIWALTIIVTIKYVLFLLR
ADNQGEGGTLSLLALLMKTANGHTAILFFMGIAGAALFIGDAMITPALSVLSAVEGLKLVTPALSDYVVPIAVVILLFLF
AVQSKGTAAVSKFFGPITLVWFLVMGAVGFMHIADDLSIFRAFNPYYAVAFLFNEGYVGIVVLGAVFLTVTGAEALYADL
GHFGRRPIQWAWFTVVFPALTLNYLGQGAFVLKNPEAMSDPFFLMFPKWALLPAVILATAATIIASQAVITGAFSLTRQA
IHLGFLPRMAIFHTSETHTGQIYLPNVNTLLMFGVMALVFIFGSSESLATAYGISVTGAMVVTTVLAFEFLRMRWNWPAW
WAAGVLLPLFALELVFLGANMLKIHDGGYVPILIAATFIVIMWTWKRGTAILHTKTRHIDIPLERFIKSIERQSEHAPVS
VPGTAIFLTSDPESTPAALLHNIKHNHVLHQQNFILTIRTANTPKVPREERVSARRLSERFTLMEVRFGFMETQNVSQAL
GLFRKSGLKFDIMSTSFYLGRRKLVPDAQSGMPHWQDRLFIALANAAIDPSDYFRLPTNRVVELGSHVII
>Mature_629_residues
SQLSAPGAENTRRLLAMALGSVGVVYGDIGTSPLYAFREALRPVSHDGVTDVEIVGLISLMIWALTIIVTIKYVLFLLRA
DNQGEGGTLSLLALLMKTANGHTAILFFMGIAGAALFIGDAMITPALSVLSAVEGLKLVTPALSDYVVPIAVVILLFLFA
VQSKGTAAVSKFFGPITLVWFLVMGAVGFMHIADDLSIFRAFNPYYAVAFLFNEGYVGIVVLGAVFLTVTGAEALYADLG
HFGRRPIQWAWFTVVFPALTLNYLGQGAFVLKNPEAMSDPFFLMFPKWALLPAVILATAATIIASQAVITGAFSLTRQAI
HLGFLPRMAIFHTSETHTGQIYLPNVNTLLMFGVMALVFIFGSSESLATAYGISVTGAMVVTTVLAFEFLRMRWNWPAWW
AAGVLLPLFALELVFLGANMLKIHDGGYVPILIAATFIVIMWTWKRGTAILHTKTRHIDIPLERFIKSIERQSEHAPVSV
PGTAIFLTSDPESTPAALLHNIKHNHVLHQQNFILTIRTANTPKVPREERVSARRLSERFTLMEVRFGFMETQNVSQALG
LFRKSGLKFDIMSTSFYLGRRKLVPDAQSGMPHWQDRLFIALANAAIDPSDYFRLPTNRVVELGSHVII

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=622, Percent_Identity=43.2475884244373, Blast_Score=527, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP1_SINMW (A6U6M1)

Other databases:

- EMBL:   CP000738
- RefSeq:   YP_001326136.1
- STRING:   A6U6M1
- GeneID:   5321278
- GenomeReviews:   CP000738_GR
- KEGG:   smd:Smed_0444
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   SDYFRLP
- ProtClustDB:   CLSK800194
- BioCyc:   SMED366394:SMED_0444-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 69122; Mature: 68991

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f9cf124)-; HASH(0x201caaf0)-; HASH(0x1f4ee910)-; HASH(0x201c8944)-; HASH(0x201d9268)-; HASH(0x201c85a8)-; HASH(0x1ec9e36c)-; HASH(0x201fc460)-; HASH(0x1fadc840)-; HASH(0x1efbc008)-; HASH(0x1fa81524)-; HASH(0x1f91b960)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLSAPGAENTRRLLAMALGSVGVVYGDIGTSPLYAFREALRPVSHDGVTDVEIVGLIS
CCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHH
LMIWALTIIVTIKYVLFLLRADNQGEGGTLSLLALLMKTANGHTAILFFMGIAGAALFIG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHH
DAMITPALSVLSAVEGLKLVTPALSDYVVPIAVVILLFLFAVQSKGTAAVSKFFGPITLV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
WFLVMGAVGFMHIADDLSIFRAFNPYYAVAFLFNEGYVGIVVLGAVFLTVTGAEALYADL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHH
GHFGRRPIQWAWFTVVFPALTLNYLGQGAFVLKNPEAMSDPFFLMFPKWALLPAVILATA
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCEEEECCCHHHHHHHHHHHH
ATIIASQAVITGAFSLTRQAIHLGFLPRMAIFHTSETHTGQIYLPNVNTLLMFGVMALVF
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEEECCCCCCCEEEECCCHHHHHHHHHHHHH
IFGSSESLATAYGISVTGAMVVTTVLAFEFLRMRWNWPAWWAAGVLLPLFALELVFLGAN
HHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
MLKIHDGGYVPILIAATFIVIMWTWKRGTAILHTKTRHIDIPLERFIKSIERQSEHAPVS
EEEEECCCCHHHHHHHHHHHHEEECCCCCEEEEECCEEECCCHHHHHHHHHHHCCCCCEE
VPGTAIFLTSDPESTPAALLHNIKHNHVLHQQNFILTIRTANTPKVPREERVSARRLSER
CCCCEEEEECCCCCCHHHHHHHHHHCCEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHH
FTLMEVRFGFMETQNVSQALGLFRKSGLKFDIMSTSFYLGRRKLVPDAQSGMPHWQDRLF
HHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCCCCCCHHHHEE
IALANAAIDPSDYFRLPTNRVVELGSHVII
EEEECCCCCCHHCEECCCHHHHHCCCCCCH
>Mature Secondary Structure 
SQLSAPGAENTRRLLAMALGSVGVVYGDIGTSPLYAFREALRPVSHDGVTDVEIVGLIS
CCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHH
LMIWALTIIVTIKYVLFLLRADNQGEGGTLSLLALLMKTANGHTAILFFMGIAGAALFIG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHH
DAMITPALSVLSAVEGLKLVTPALSDYVVPIAVVILLFLFAVQSKGTAAVSKFFGPITLV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
WFLVMGAVGFMHIADDLSIFRAFNPYYAVAFLFNEGYVGIVVLGAVFLTVTGAEALYADL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHH
GHFGRRPIQWAWFTVVFPALTLNYLGQGAFVLKNPEAMSDPFFLMFPKWALLPAVILATA
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCEEEECCCHHHHHHHHHHHH
ATIIASQAVITGAFSLTRQAIHLGFLPRMAIFHTSETHTGQIYLPNVNTLLMFGVMALVF
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEEECCCCCCCEEEECCCHHHHHHHHHHHHH
IFGSSESLATAYGISVTGAMVVTTVLAFEFLRMRWNWPAWWAAGVLLPLFALELVFLGAN
HHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
MLKIHDGGYVPILIAATFIVIMWTWKRGTAILHTKTRHIDIPLERFIKSIERQSEHAPVS
EEEEECCCCHHHHHHHHHHHHEEECCCCCEEEEECCEEECCCHHHHHHHHHHHCCCCCEE
VPGTAIFLTSDPESTPAALLHNIKHNHVLHQQNFILTIRTANTPKVPREERVSARRLSER
CCCCEEEEECCCCCCHHHHHHHHHHCCEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHH
FTLMEVRFGFMETQNVSQALGLFRKSGLKFDIMSTSFYLGRRKLVPDAQSGMPHWQDRLF
HHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCCCCCCHHHHEE
IALANAAIDPSDYFRLPTNRVVELGSHVII
EEEECCCCCCHHCEECCCHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA