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The map label for this gene is infA [H]

Identifier: 150395438

GI number: 150395438

Start: 237499

End: 237762

Strand: Direct

Name: infA [H]

Synonym: Smed_0211

Alternate gene names: 150395438

Gene position: 237499-237762 (Clockwise)

Preceding gene: 150395437

Following gene: 150395439

Centisome position: 6.28

GC content: 55.68

Gene sequence:

>264_bases
ATGCCTGTTGCATCCGCTATTGAACACGAGAAAGAACATTTCTGCATGGCGAAAGAAGAAGTCCTCGAATTTCCGGGCGT
GGTCACCGAATTGCTTCCCAACGCGACATTTCGCGTGAAGCTTGAAAACGAGCACGAGATCATCGCCCACACGGCGGGCC
GCATGCGCAAGAACCGTATCCGGGTTCTGGCCGGCGACAAGGTGCTGGTCGAGATGACGCCCTACGATCTGACCAAGGGC
CGTATCACCTACCGCTTCAAGTAG

Upstream 100 bases:

>100_bases
TACGGTGATCCGGGGCGCACGGATCGGGTACCCGAAAAAGCCTTATCAAAGCGGTTCACAAAGCCGCGGCGATTGTGTAG
TTTCCGGCAACTTTTTGAGG

Downstream 100 bases:

>100_bases
GCCCCGGCCAATTGCACGTCGCCCAGAAGTGCAAAGCCGTTTTGGGCAGCGACATGCATGACATTGGCGCAAACCTCCGG
GAACCACGGCTCGCATCGAT

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 86

Protein sequence:

>87_residues
MPVASAIEHEKEHFCMAKEEVLEFPGVVTELLPNATFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKG
RITYRFK

Sequences:

>Translated_87_residues
MPVASAIEHEKEHFCMAKEEVLEFPGVVTELLPNATFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKG
RITYRFK
>Mature_86_residues
PVASAIEHEKEHFCMAKEEVLEFPGVVTELLPNATFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKGR
ITYRFK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=62.8571428571429, Blast_Score=97, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 10052; Mature: 9921

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVASAIEHEKEHFCMAKEEVLEFPGVVTELLPNATFRVKLENEHEIIAHTAGRMRKNRI
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCEEEECCCCHHCCCEE
RVLAGDKVLVEMTPYDLTKGRITYRFK
EEEECCEEEEEECCCCCCCCEEEEEEC
>Mature Secondary Structure 
PVASAIEHEKEHFCMAKEEVLEFPGVVTELLPNATFRVKLENEHEIIAHTAGRMRKNRI
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCEEEECCCCHHCCCEE
RVLAGDKVLVEMTPYDLTKGRITYRFK
EEEECCEEEEEECCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]