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The map label for this gene is mcpA [H]

Identifier: 150395310

GI number: 150395310

Start: 89239

End: 91236

Strand: Direct

Name: mcpA [H]

Synonym: Smed_0082

Alternate gene names: 150395310

Gene position: 89239-91236 (Clockwise)

Preceding gene: 150395304

Following gene: 150395311

Centisome position: 2.36

GC content: 61.41

Gene sequence:

>1998_bases
ATGAAAATACGCGGGAAAATTAACTTGATCGTCGGCATCATGAGTCTGCTGGCGATAGCGATCACCGGTATGTCGTTGCT
TATCGTGAGCGAGTACAACCAGCGGCTCGGTGAATACCAGAACGCTTCCGACCGGGCCTTCAAAGGCGAGCGGCTCAATC
GTCTCGTAACGGCCGTGGTCATGGAGGCGCGGGGCATCTATGCGGCGCCGACGGTTGAAAAGGCAAAGCCATTTGCCGAG
GGCATTCTCAAAAATCTCGGCAAGATAGATACGCTGCTGGAGGAGTGGCGGCCGCTGGTGCCGGCCGACGTCCTGCCCGC
CTTCGATACCCTCGTAAAGCGCGCGGAGGAATTCAAGGTGTTCCGAAGTGAGACGGCGCGCCTGGGCACGGAAGTTGCGC
CGCAGGCGGCCAACGAGCAGGGCAACAATGAAGCCAATCGGGCCAACCGCAAGGCTTTTCAAGCTGAGATCGACGTCGTC
GTGGACGCGAACCTTGCCTTGCTTCAGACGATTACCGCCGACATCGCCGAATACAAGCGCTCGATCGTGCTGATCGTGCT
TGCAACCGCAGCTCTTGGCATGCTGGCCGGGATCGGCGCTGCCTTCTACATTGCGACCAACCACCTCAGCCGCCCGATTC
TCGATCTGACGGCCAAGATGAAGGTGCTTGCCGGCGGTGACCTCACGGCGGATGTGCCCTTCGCCGGGCGCAAGGACGAG
ATCGGCGATATGGCGGCAGCGGTCGAAGTCTTCAAACAGAACAGCCTTGCCGTTCGAGAGCTCAACGCCCAGGAAGAAGT
CCTGCGTGGAAAGAGCGCGGACCTGCAGTCGAGCATCGCCACGGTCGTCGCGGCGGCTGCGGCGGGCGATTTCACCCAGC
GCATCAGCAAGGACTATGACAACGACGATCTCAACCGTTTTGCGGCAAGCGTCAACGAACTGGTCAACAGTGTCGATACC
GGTATTGCCGAGACCCGAAGGGTCATTGCGAGCCTGGCAACGGGCGACCTAACGCAGAGCATGAAGGGTCAGTTCCAGGG
CGCATTCGCGGAGCTGCAGACGAACGTCAACGACACCTTGCAGACGCTTCAGAAGACGCTCCGCGAGGTCCGCACGACGA
CGGACTCGATCAATGGAAACTCTACCGAGCTGCGCAGTGCTGCCGACGACCTTTCCAAGCGGACGGAACAGCAGGCCGCG
GCGCTTGAGGAAACCTCGGCAGCGCTCGACCAGATAACCGCCGCAGTCCGCAATTCGACCGAACGGGCTCATGAGGCGAC
CGTGATGGTTACGGAGGCGAAGGACAGTGCTGCGCAGTCGGCATCGGTCGTCCGCAATGCCATCGATGCCATGGGCCGGA
TCGAACAGGCTTCGAGCGAGATCGGCCAGATTACCAACGTCATCGACGAAATTGCCTTCCAGACCAACCTGCTGGCCCTG
AACGCAGGCGTCGAGGCGGCACGCGCCGGAGATGCCGGCAAGGGTTTCGCCGTCGTCGCCCAGGAGGTCCGTGAACTCGC
CCAGCGTGCCGCCAGCGCCGCCAAGGATATCAAATCGCTGATTTCCAAGTCCGGTGACGAGGTGTCAACCGGCGTCAAGC
TCGTACAGGCAACGGGAGCGGCGCTCGGCCAGATCGAGACGCGCGTCCTCAAGATCAACGATCACATCCATTCGATCGCG
ACGGCCGCGCGTGAGCAATCGACGGGCCTTGGCGAAGTCAGCACTGCCGTCAACCAGATGGATCAGGTCACCCAGCGCAA
TGCCGCCATGGTGGAAGAGGCGAATGCTGCCACGCATAAGCTATCCGCTGAAGCTGACAACCTTGCCAACCTGATCGCCT
ATTTCAAGATCGAGCGCGACCCGGTGCGTACGATCACGCCGGCAAGGGAAACGAACCGCCCCGTTGCATCGCCCGCCCGC
CGTATGATGGGGTCGGTCGCGCGCGCTTTCGGCAACGGTTCCGCCGCGGTCGCCCGTGATGATTGGGAGGAATTCTGA

Upstream 100 bases:

>100_bases
CTTTGTTAACCGTGCGCATTTTAGCATTTACTCAGTTGCGTGCAGGCCGTGAGTTGTTCCCGTCTGGGGCGAGTGGGCGG
CTGGGGGACAGGAACAGGAC

Downstream 100 bases:

>100_bases
ACGGCTCGGAGCTCAACCAGGAAAGTGCACACACTATTCTTCATCCCGCTCCGGCTGTGATCCCCTCGGGTATCGGCATA
GGGCTTCTCGCGGCGGCCGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MKIRGKINLIVGIMSLLAIAITGMSLLIVSEYNQRLGEYQNASDRAFKGERLNRLVTAVVMEARGIYAAPTVEKAKPFAE
GILKNLGKIDTLLEEWRPLVPADVLPAFDTLVKRAEEFKVFRSETARLGTEVAPQAANEQGNNEANRANRKAFQAEIDVV
VDANLALLQTITADIAEYKRSIVLIVLATAALGMLAGIGAAFYIATNHLSRPILDLTAKMKVLAGGDLTADVPFAGRKDE
IGDMAAAVEVFKQNSLAVRELNAQEEVLRGKSADLQSSIATVVAAAAAGDFTQRISKDYDNDDLNRFAASVNELVNSVDT
GIAETRRVIASLATGDLTQSMKGQFQGAFAELQTNVNDTLQTLQKTLREVRTTTDSINGNSTELRSAADDLSKRTEQQAA
ALEETSAALDQITAAVRNSTERAHEATVMVTEAKDSAAQSASVVRNAIDAMGRIEQASSEIGQITNVIDEIAFQTNLLAL
NAGVEAARAGDAGKGFAVVAQEVRELAQRAASAAKDIKSLISKSGDEVSTGVKLVQATGAALGQIETRVLKINDHIHSIA
TAAREQSTGLGEVSTAVNQMDQVTQRNAAMVEEANAATHKLSAEADNLANLIAYFKIERDPVRTITPARETNRPVASPAR
RMMGSVARAFGNGSAAVARDDWEEF

Sequences:

>Translated_665_residues
MKIRGKINLIVGIMSLLAIAITGMSLLIVSEYNQRLGEYQNASDRAFKGERLNRLVTAVVMEARGIYAAPTVEKAKPFAE
GILKNLGKIDTLLEEWRPLVPADVLPAFDTLVKRAEEFKVFRSETARLGTEVAPQAANEQGNNEANRANRKAFQAEIDVV
VDANLALLQTITADIAEYKRSIVLIVLATAALGMLAGIGAAFYIATNHLSRPILDLTAKMKVLAGGDLTADVPFAGRKDE
IGDMAAAVEVFKQNSLAVRELNAQEEVLRGKSADLQSSIATVVAAAAAGDFTQRISKDYDNDDLNRFAASVNELVNSVDT
GIAETRRVIASLATGDLTQSMKGQFQGAFAELQTNVNDTLQTLQKTLREVRTTTDSINGNSTELRSAADDLSKRTEQQAA
ALEETSAALDQITAAVRNSTERAHEATVMVTEAKDSAAQSASVVRNAIDAMGRIEQASSEIGQITNVIDEIAFQTNLLAL
NAGVEAARAGDAGKGFAVVAQEVRELAQRAASAAKDIKSLISKSGDEVSTGVKLVQATGAALGQIETRVLKINDHIHSIA
TAAREQSTGLGEVSTAVNQMDQVTQRNAAMVEEANAATHKLSAEADNLANLIAYFKIERDPVRTITPARETNRPVASPAR
RMMGSVARAFGNGSAAVARDDWEEF
>Mature_665_residues
MKIRGKINLIVGIMSLLAIAITGMSLLIVSEYNQRLGEYQNASDRAFKGERLNRLVTAVVMEARGIYAAPTVEKAKPFAE
GILKNLGKIDTLLEEWRPLVPADVLPAFDTLVKRAEEFKVFRSETARLGTEVAPQAANEQGNNEANRANRKAFQAEIDVV
VDANLALLQTITADIAEYKRSIVLIVLATAALGMLAGIGAAFYIATNHLSRPILDLTAKMKVLAGGDLTADVPFAGRKDE
IGDMAAAVEVFKQNSLAVRELNAQEEVLRGKSADLQSSIATVVAAAAAGDFTQRISKDYDNDDLNRFAASVNELVNSVDT
GIAETRRVIASLATGDLTQSMKGQFQGAFAELQTNVNDTLQTLQKTLREVRTTTDSINGNSTELRSAADDLSKRTEQQAA
ALEETSAALDQITAAVRNSTERAHEATVMVTEAKDSAAQSASVVRNAIDAMGRIEQASSEIGQITNVIDEIAFQTNLLAL
NAGVEAARAGDAGKGFAVVAQEVRELAQRAASAAKDIKSLISKSGDEVSTGVKLVQATGAALGQIETRVLKINDHIHSIA
TAAREQSTGLGEVSTAVNQMDQVTQRNAAMVEEANAATHKLSAEADNLANLIAYFKIERDPVRTITPARETNRPVASPAR
RMMGSVARAFGNGSAAVARDDWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=317, Percent_Identity=40.6940063091483, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI1788194, Length=296, Percent_Identity=42.9054054054054, Blast_Score=205, Evalue=9e-54,
Organism=Escherichia coli, GI2367378, Length=316, Percent_Identity=42.0886075949367, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1787690, Length=294, Percent_Identity=40.4761904761905, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1789453, Length=228, Percent_Identity=39.0350877192982, Blast_Score=155, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71034; Mature: 71034

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRGKINLIVGIMSLLAIAITGMSLLIVSEYNQRLGEYQNASDRAFKGERLNRLVTAVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
MEARGIYAAPTVEKAKPFAEGILKNLGKIDTLLEEWRPLVPADVLPAFDTLVKRAEEFKV
HHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FRSETARLGTEVAPQAANEQGNNEANRANRKAFQAEIDVVVDANLALLQTITADIAEYKR
HHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHH
SIVLIVLATAALGMLAGIGAAFYIATNHLSRPILDLTAKMKVLAGGDLTADVPFAGRKDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCEECCCCCCCCCH
IGDMAAAVEVFKQNSLAVRELNAQEEVLRGKSADLQSSIATVVAAAAAGDFTQRISKDYD
HHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
NDDLNRFAASVNELVNSVDTGIAETRRVIASLATGDLTQSMKGQFQGAFAELQTNVNDTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QTLQKTLREVRTTTDSINGNSTELRSAADDLSKRTEQQAAALEETSAALDQITAAVRNST
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAHEATVMVTEAKDSAAQSASVVRNAIDAMGRIEQASSEIGQITNVIDEIAFQTNLLAL
HHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NAGVEAARAGDAGKGFAVVAQEVRELAQRAASAAKDIKSLISKSGDEVSTGVKLVQATGA
ECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALGQIETRVLKINDHIHSIATAAREQSTGLGEVSTAVNQMDQVTQRNAAMVEEANAATHK
HHHHHHHHEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAEADNLANLIAYFKIERDPVRTITPARETNRPVASPARRMMGSVARAFGNGSAAVARD
HHCCHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCEEECC
DWEEF
CCCCC
>Mature Secondary Structure
MKIRGKINLIVGIMSLLAIAITGMSLLIVSEYNQRLGEYQNASDRAFKGERLNRLVTAVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
MEARGIYAAPTVEKAKPFAEGILKNLGKIDTLLEEWRPLVPADVLPAFDTLVKRAEEFKV
HHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FRSETARLGTEVAPQAANEQGNNEANRANRKAFQAEIDVVVDANLALLQTITADIAEYKR
HHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHH
SIVLIVLATAALGMLAGIGAAFYIATNHLSRPILDLTAKMKVLAGGDLTADVPFAGRKDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCEECCCCCCCCCH
IGDMAAAVEVFKQNSLAVRELNAQEEVLRGKSADLQSSIATVVAAAAAGDFTQRISKDYD
HHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
NDDLNRFAASVNELVNSVDTGIAETRRVIASLATGDLTQSMKGQFQGAFAELQTNVNDTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QTLQKTLREVRTTTDSINGNSTELRSAADDLSKRTEQQAAALEETSAALDQITAAVRNST
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAHEATVMVTEAKDSAAQSASVVRNAIDAMGRIEQASSEIGQITNVIDEIAFQTNLLAL
HHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NAGVEAARAGDAGKGFAVVAQEVRELAQRAASAAKDIKSLISKSGDEVSTGVKLVQATGA
ECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALGQIETRVLKINDHIHSIATAAREQSTGLGEVSTAVNQMDQVTQRNAAMVEEANAATHK
HHHHHHHHEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAEADNLANLIAYFKIERDPVRTITPARETNRPVASPARRMMGSVARAFGNGSAAVARD
HHCCHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCEEECC
DWEEF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]