Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15004767

GI number: 15004767

Start: 63631

End: 64926

Strand: Direct

Name: Not Available

Synonym: CA_P0063

Alternate gene names: 15004767

Gene position: 63631-64926 (Clockwise)

Preceding gene: 15004760

Following gene: 15004769

Centisome position: 33.14

GC content: 33.64

Gene sequence:

>1296_bases
ATGGATAAGTTAAGTATACGTGAAGACAACTACAATATAAAACATAAAACAATTTCGTTAAATAGAGCTTCAAGTGTTAC
AAGAAATTTAAAAGGATTATTAAAGTTTTTAGGACCAGCTTTTGTTGTCAGTGTAGCCTACATTGATCCTGGTAATTTTG
CTACAAACATTAGTGGAGGTTCCAGCTTCAATTATAATCTTATATGGGTTATTCTTTGGAGTAATTTGATGGCTATATTT
CTTCAAACTATGTCTGCAAAATTAGGAATTGCAACTGGCTGCAGCTTACCTGAAATGTGTGCTAAGGTTTTTTCAAAAAG
AGCAAATTGGATATTTTGGATTGTTGGCGAGTTGGGTGCTATGGCAACGGATTTGGCAGAGTTTATTGGAGGAACTTTAG
GCTTGTATTTATTATTTAGAATACCAATGATTTATGCAGGACTACTTACAGGAGTTTTAACTTTTATAATAGTTTACATG
GAAAAGTATGGTCAAAAGATGGTAGAAACCATAATAGCTGCTTTAATAGCTGTAATATGTGTTGCCTATACAATAGAGTT
ATTTCTTGCCAGGCCAGCGTGGACACAGGTAGGAATGCATACTTTAATTCCGAGTTTACCTAATGGAGAAGCTGTTCTAA
TAGCGGTTGGTATGTTGGGGGCTACGGTTATGCCGCATGTAATATACCTTCATTCCGAATTGGTTCAGCATAGAAATACA
AATTCATCTGATAAAGAAAAGTTGCATCACTTAAAGATGGAGAAAATCGATATACTTATAGCAATGAATATTGCCTTTGT
TGTCAATGCGGCAATGGTAATTGTATCTGCAGCCGTATTCTTTAAGCATGGAATAAAAGTAAGTACAATAGAAGAAGCAC
ATAGATCACTACAGCCTTTACTCGGAAATTTATCCAGTGGTGCCTTTGGAATAGCGCTTTTAGCATCAGGATTATCTTCA
TCCGCCGTAGGAACGATGGCAGGGCAAACTATTATGAAAGGCTTTGTTAATTTAAGCATACCTATAAATTTAAGAAGAAT
TATAACTATGCTTCCAGCACTAATTATCATAGCTTTAGGTATAAATCCAATGAGAGTATTAGTTTTAAGTCAAGTTGCTT
TGAGTTTTATACTTCCGTTTCCTATAATTCAAATGCTTTTAATAGCTGGGCGTAAAGATTTAATGGGAATTTTAGTTAAT
AAGAAATTTACTAAAATTGTAGGCTTTATAATTGCAACCATGATAATTTTGCTGAATATAATACTTTTATATTTAACCTT
TACAGGTCAAACTTAA

Upstream 100 bases:

>100_bases
TTCATAGTGTATTGTAGGTCCCAAATTTAGTTTAATCTAACTTTCTTAAAGCTATGTAACATTTTGGGGCGATACATGAG
GTAAAGAAGGTAGTGTATAT

Downstream 100 bases:

>100_bases
GGTTTAAAAGGTTTTATTGTAATCAGGATATAGCAAAGATTCAAATTCTATTTTCCGTATAAATCATTGCCGTATCCTGT
TAAAGGTTTAATACTATAGT

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MDKLSIREDNYNIKHKTISLNRASSVTRNLKGLLKFLGPAFVVSVAYIDPGNFATNISGGSSFNYNLIWVILWSNLMAIF
LQTMSAKLGIATGCSLPEMCAKVFSKRANWIFWIVGELGAMATDLAEFIGGTLGLYLLFRIPMIYAGLLTGVLTFIIVYM
EKYGQKMVETIIAALIAVICVAYTIELFLARPAWTQVGMHTLIPSLPNGEAVLIAVGMLGATVMPHVIYLHSELVQHRNT
NSSDKEKLHHLKMEKIDILIAMNIAFVVNAAMVIVSAAVFFKHGIKVSTIEEAHRSLQPLLGNLSSGAFGIALLASGLSS
SAVGTMAGQTIMKGFVNLSIPINLRRIITMLPALIIIALGINPMRVLVLSQVALSFILPFPIIQMLLIAGRKDLMGILVN
KKFTKIVGFIIATMIILLNIILLYLTFTGQT

Sequences:

>Translated_431_residues
MDKLSIREDNYNIKHKTISLNRASSVTRNLKGLLKFLGPAFVVSVAYIDPGNFATNISGGSSFNYNLIWVILWSNLMAIF
LQTMSAKLGIATGCSLPEMCAKVFSKRANWIFWIVGELGAMATDLAEFIGGTLGLYLLFRIPMIYAGLLTGVLTFIIVYM
EKYGQKMVETIIAALIAVICVAYTIELFLARPAWTQVGMHTLIPSLPNGEAVLIAVGMLGATVMPHVIYLHSELVQHRNT
NSSDKEKLHHLKMEKIDILIAMNIAFVVNAAMVIVSAAVFFKHGIKVSTIEEAHRSLQPLLGNLSSGAFGIALLASGLSS
SAVGTMAGQTIMKGFVNLSIPINLRRIITMLPALIIIALGINPMRVLVLSQVALSFILPFPIIQMLLIAGRKDLMGILVN
KKFTKIVGFIIATMIILLNIILLYLTFTGQT
>Mature_431_residues
MDKLSIREDNYNIKHKTISLNRASSVTRNLKGLLKFLGPAFVVSVAYIDPGNFATNISGGSSFNYNLIWVILWSNLMAIF
LQTMSAKLGIATGCSLPEMCAKVFSKRANWIFWIVGELGAMATDLAEFIGGTLGLYLLFRIPMIYAGLLTGVLTFIIVYM
EKYGQKMVETIIAALIAVICVAYTIELFLARPAWTQVGMHTLIPSLPNGEAVLIAVGMLGATVMPHVIYLHSELVQHRNT
NSSDKEKLHHLKMEKIDILIAMNIAFVVNAAMVIVSAAVFFKHGIKVSTIEEAHRSLQPLLGNLSSGAFGIALLASGLSS
SAVGTMAGQTIMKGFVNLSIPINLRRIITMLPALIIIALGINPMRVLVLSQVALSFILPFPIIQMLLIAGRKDLMGILVN
KKFTKIVGFIIATMIILLNIILLYLTFTGQT

Specific function: H(+)-stimulated, highly selective, manganese uptake system

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family

Homologues:

Organism=Homo sapiens, GI109255241, Length=435, Percent_Identity=28.2758620689655, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI295293167, Length=462, Percent_Identity=29.2207792207792, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI295293178, Length=462, Percent_Identity=29.004329004329, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI295293171, Length=459, Percent_Identity=29.1938997821351, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI295293169, Length=459, Percent_Identity=29.1938997821351, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI295293175, Length=462, Percent_Identity=29.004329004329, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI295293173, Length=462, Percent_Identity=29.004329004329, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI10835169, Length=462, Percent_Identity=29.004329004329, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI1788736, Length=421, Percent_Identity=44.1805225653207, Blast_Score=357, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI17569473, Length=366, Percent_Identity=30.6010928961749, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71999499, Length=448, Percent_Identity=27.0089285714286, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI193210616, Length=469, Percent_Identity=25.3731343283582, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71993856, Length=249, Percent_Identity=29.3172690763052, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324450, Length=456, Percent_Identity=30.7017543859649, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6321841, Length=438, Percent_Identity=32.1917808219178, Blast_Score=176, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6323062, Length=400, Percent_Identity=32.25, Blast_Score=168, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24648607, Length=465, Percent_Identity=28.3870967741935, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI281362176, Length=465, Percent_Identity=28.3870967741935, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24648609, Length=465, Percent_Identity=28.3870967741935, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI45553443, Length=445, Percent_Identity=28.5393258426966, Blast_Score=192, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNTH_CLOAB (Q97TN5)

Other databases:

- EMBL:   AE001438
- RefSeq:   NP_149227.1
- GeneID:   1116068
- GenomeReviews:   AE001438_GR
- KEGG:   cac:CA_P0063
- NMPDR:   fig|272562.1.peg.62
- HOGENOM:   HBG312498
- OMA:   FATNIRA
- PhylomeDB:   Q97TN5
- ProtClustDB:   PRK00701
- BioCyc:   CACE272562:CAP0063-MONOMER
- HAMAP:   MF_00221
- InterPro:   IPR023056
- InterPro:   IPR001046
- PANTHER:   PTHR11706
- PRINTS:   PR00447
- TIGRFAMs:   TIGR01197

Pfam domain/function: PF01566 Nramp

EC number: NA

Molecular weight: Translated: 47026; Mature: 47026

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xbba7d98)-; HASH(0xbbb46c0)-; HASH(0xbbb493c)-; HASH(0xbbb2560)-; HASH(0xbbc2e40)-; HASH(0xbbb67a0)-; HASH(0xbbcad14)-; HASH(0xbbb2254)-; HASH(0xaf76ec0)-; HASH(0xbbbe9d4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLSIREDNYNIKHKTISLNRASSVTRNLKGLLKFLGPAFVVSVAYIDPGNFATNISGG
CCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCHHHHEEEEEECCCCCEEECCCC
SSFNYNLIWVILWSNLMAIFLQTMSAKLGIATGCSLPEMCAKVFSKRANWIFWIVGELGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHH
MATDLAEFIGGTLGLYLLFRIPMIYAGLLTGVLTFIIVYMEKYGQKMVETIIAALIAVIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAYTIELFLARPAWTQVGMHTLIPSLPNGEAVLIAVGMLGATVMPHVIYLHSELVQHRNT
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
NSSDKEKLHHLKMEKIDILIAMNIAFVVNAAMVIVSAAVFFKHGIKVSTIEEAHRSLQPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
LGNLSSGAFGIALLASGLSSSAVGTMAGQTIMKGFVNLSIPINLRRIITMLPALIIIALG
HCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHC
INPMRVLVLSQVALSFILPFPIIQMLLIAGRKDLMGILVNKKFTKIVGFIIATMIILLNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLYLTFTGQT
HHHHHHHCCCH
>Mature Secondary Structure
MDKLSIREDNYNIKHKTISLNRASSVTRNLKGLLKFLGPAFVVSVAYIDPGNFATNISGG
CCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCHHHHEEEEEECCCCCEEECCCC
SSFNYNLIWVILWSNLMAIFLQTMSAKLGIATGCSLPEMCAKVFSKRANWIFWIVGELGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHH
MATDLAEFIGGTLGLYLLFRIPMIYAGLLTGVLTFIIVYMEKYGQKMVETIIAALIAVIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAYTIELFLARPAWTQVGMHTLIPSLPNGEAVLIAVGMLGATVMPHVIYLHSELVQHRNT
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
NSSDKEKLHHLKMEKIDILIAMNIAFVVNAAMVIVSAAVFFKHGIKVSTIEEAHRSLQPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
LGNLSSGAFGIALLASGLSSSAVGTMAGQTIMKGFVNLSIPINLRRIITMLPALIIIALG
HCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHC
INPMRVLVLSQVALSFILPFPIIQMLLIAGRKDLMGILVNKKFTKIVGFIIATMIILLNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLYLTFTGQT
HHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11466286