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The map label for this gene is bgla

Identifier: 15004715

GI number: 15004715

Start: 11140

End: 12549

Strand: Direct

Name: bgla

Synonym: CA_P0010

Alternate gene names: 15004715

Gene position: 11140-12549 (Clockwise)

Preceding gene: 15004714

Following gene: 15004716

Centisome position: 5.8

GC content: 33.9

Gene sequence:

>1410_bases
ATGAGACATAGCAAACTAAAGGATTTTCCAAAAGATTTTCTTTGGAGTGCATCAACTAGTGCGTATCAGGTTGAAGGTGC
ATGGAATGAGGACGGAAAAGGGATGTCGGTGCAGGATGCAAAAACTTCACTTCCAGAAGGAACAAGTGATTTTAAGGTTG
CCAGCGATCATTATCACCATTTTGAGGAGGATATTGCTTTTTTAGGAGAAATGGGACTTAAAGCCTATAGGTTTTCAATT
TCTTGGACCCGAATAATTCCAGATGGTGATGGAAAGATAAATACAAAGGGTGTACAATTCTATCATAAATTAATTGATGC
TTGTTTGAGTTATAACATAGAGCCAATTGTAACTATGTATCATTTTGATCTTCCTTTTGAATTGGAGAAAAAAGGTGGTT
GGAATAATAGAACTACTATTGATGCATTTTTAAAATTTAGTAAGATTTTGTTTGAACAATACGGCTCGAAGGTAAAGTAT
TTCTTAACTATTAATGAGCAGAACATGATGATTCTTCATGGAGCTGCTATTGGTACGTCTAAAGGTTCTGGTATAAATAT
ATGGAAGGAATTATATCAGCAAAACCACAACATGTTAGTTGCACAGGCAAAAGCTATGGAATTATGCCATAAACTTTGTC
CTAATTCTAAAATAGGTCCTGCGCCTAATATAGCTTCAATATATCCAGCATCCTCAAAGCCAGAAGATTACCTTGCTGCA
CAGAATTTTACAGCTATAAGAAATTGGCTTTATCTTGATATGGCCGTTTTTGGAAGGTATAATTCAACAGCGTGGTCATA
CCTTGAGGAAATAGATGCTGTGCCAAAAATAGAAGAAGGAGACATGGAGATATTAAGAAATGCAAAACCAGATTTTATAG
CTTTTAATTACTATAATACAGCTACAGTTAAAGCAAATAATGATGCTAAAAAGGTACAAGATTCAAGTGGAGATCAACAA
TTAGCAGTTTTTGAAGCAGGAGTATTTGAAGGAGTCCAAAATCCTAATCTTGAAAAGACGGAATTTGGGTGGGAAATAGA
TCCTGTTGGTTTTAGAATAACTTTAAGAGAAGTATATGATAGGTATAATCTTCCAATTATAGTAACTGAAAATGGTCTTG
GAGCTTTTGATAAGTTGGAGGATGGAACAGTTCATGATGATTATAGAATTGAATACTATAAGAAACATTTGCATGAAATA
AAAGAAGCTATTACAGATGGTGTGAAGGTATTTGGGTATTCTCCATGGAGTGCAATTGATCTTGTTTCAACACATCAAGG
AGTCACTAAAAGGTATGGCTTTATATATGTAAATCGTGATGAATTCGATTTGAAGGATTTAAAGAGATATAAAAAAGATA
GTTTTTATTGGTACAAGAAGGTTATAGAAGAGAATGGGAATAACTTATAA

Upstream 100 bases:

>100_bases
AAAAGAGCTTGGCATAAACGTTGATTGTAAAATTTATGAATGGATAAAAAGCTAGAAATTAAACTTTTTAAATACTATGT
AAATATGGAGGTATGTAATA

Downstream 100 bases:

>100_bases
AAAATAGAGTATTGATGTAGAGCCTTATGGGTTTTACATCAATACTTTATTTTTTAAGACTTATTTGTGATTGTGTGGTA
TAAATATATTAAGATAAAAT

Product: Beta_glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MRHSKLKDFPKDFLWSASTSAYQVEGAWNEDGKGMSVQDAKTSLPEGTSDFKVASDHYHHFEEDIAFLGEMGLKAYRFSI
SWTRIIPDGDGKINTKGVQFYHKLIDACLSYNIEPIVTMYHFDLPFELEKKGGWNNRTTIDAFLKFSKILFEQYGSKVKY
FLTINEQNMMILHGAAIGTSKGSGINIWKELYQQNHNMLVAQAKAMELCHKLCPNSKIGPAPNIASIYPASSKPEDYLAA
QNFTAIRNWLYLDMAVFGRYNSTAWSYLEEIDAVPKIEEGDMEILRNAKPDFIAFNYYNTATVKANNDAKKVQDSSGDQQ
LAVFEAGVFEGVQNPNLEKTEFGWEIDPVGFRITLREVYDRYNLPIIVTENGLGAFDKLEDGTVHDDYRIEYYKKHLHEI
KEAITDGVKVFGYSPWSAIDLVSTHQGVTKRYGFIYVNRDEFDLKDLKRYKKDSFYWYKKVIEENGNNL

Sequences:

>Translated_469_residues
MRHSKLKDFPKDFLWSASTSAYQVEGAWNEDGKGMSVQDAKTSLPEGTSDFKVASDHYHHFEEDIAFLGEMGLKAYRFSI
SWTRIIPDGDGKINTKGVQFYHKLIDACLSYNIEPIVTMYHFDLPFELEKKGGWNNRTTIDAFLKFSKILFEQYGSKVKY
FLTINEQNMMILHGAAIGTSKGSGINIWKELYQQNHNMLVAQAKAMELCHKLCPNSKIGPAPNIASIYPASSKPEDYLAA
QNFTAIRNWLYLDMAVFGRYNSTAWSYLEEIDAVPKIEEGDMEILRNAKPDFIAFNYYNTATVKANNDAKKVQDSSGDQQ
LAVFEAGVFEGVQNPNLEKTEFGWEIDPVGFRITLREVYDRYNLPIIVTENGLGAFDKLEDGTVHDDYRIEYYKKHLHEI
KEAITDGVKVFGYSPWSAIDLVSTHQGVTKRYGFIYVNRDEFDLKDLKRYKKDSFYWYKKVIEENGNNL
>Mature_469_residues
MRHSKLKDFPKDFLWSASTSAYQVEGAWNEDGKGMSVQDAKTSLPEGTSDFKVASDHYHHFEEDIAFLGEMGLKAYRFSI
SWTRIIPDGDGKINTKGVQFYHKLIDACLSYNIEPIVTMYHFDLPFELEKKGGWNNRTTIDAFLKFSKILFEQYGSKVKY
FLTINEQNMMILHGAAIGTSKGSGINIWKELYQQNHNMLVAQAKAMELCHKLCPNSKIGPAPNIASIYPASSKPEDYLAA
QNFTAIRNWLYLDMAVFGRYNSTAWSYLEEIDAVPKIEEGDMEILRNAKPDFIAFNYYNTATVKANNDAKKVQDSSGDQQ
LAVFEAGVFEGVQNPNLEKTEFGWEIDPVGFRITLREVYDRYNLPIIVTENGLGAFDKLEDGTVHDDYRIEYYKKHLHEI
KEAITDGVKVFGYSPWSAIDLVSTHQGVTKRYGFIYVNRDEFDLKDLKRYKKDSFYWYKKVIEENGNNL

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=477, Percent_Identity=32.7044025157233, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI110681710, Length=486, Percent_Identity=32.3045267489712, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI13273313, Length=481, Percent_Identity=30.3534303534304, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI28376633, Length=472, Percent_Identity=30.7203389830508, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI24497614, Length=487, Percent_Identity=29.7741273100616, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI190360571, Length=98, Percent_Identity=46.9387755102041, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI2367174, Length=485, Percent_Identity=39.7938144329897, Blast_Score=351, Evalue=4e-98,
Organism=Escherichia coli, GI2367270, Length=480, Percent_Identity=40, Blast_Score=344, Evalue=8e-96,
Organism=Escherichia coli, GI1789070, Length=488, Percent_Identity=37.5, Blast_Score=324, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI17552856, Length=484, Percent_Identity=30.9917355371901, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17539390, Length=478, Percent_Identity=30.1255230125523, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI21356577, Length=487, Percent_Identity=29.3634496919918, Blast_Score=200, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53810; Mature: 53810

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSKLKDFPKDFLWSASTSAYQVEGAWNEDGKGMSVQDAKTSLPEGTSDFKVASDHYHH
CCCCCCHHCCHHHHHCCCCCEEEEECCCCCCCCCCEECHHHHCCCCCCCCCEECCHHHHH
FEEDIAFLGEMGLKAYRFSISWTRIIPDGDGKINTKGVQFYHKLIDACLSYNIEPIVTMY
HHHHHHHHHHCCCEEEEEEEEEEEEEECCCCEECCHHHHHHHHHHHHHHCCCCCEEEEEE
HFDLPFELEKKGGWNNRTTIDAFLKFSKILFEQYGSKVKYFLTINEQNMMILHGAAIGTS
EECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEEECCC
KGSGINIWKELYQQNHNMLVAQAKAMELCHKLCPNSKIGPAPNIASIYPASSKPEDYLAA
CCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHH
QNFTAIRNWLYLDMAVFGRYNSTAWSYLEEIDAVPKIEEGDMEILRNAKPDFIAFNYYNT
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEEEEE
ATVKANNDAKKVQDSSGDQQLAVFEAGVFEGVQNPNLEKTEFGWEIDPVGFRITLREVYD
EEEEECCCHHHHCCCCCCCEEEEEECHHHHCCCCCCCCCCCCCCEECCCCEEEEHHHHHH
RYNLPIIVTENGLGAFDKLEDGTVHDDYRIEYYKKHLHEIKEAITDGVKVFGYSPWSAID
HCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHH
LVSTHQGVTKRYGFIYVNRDEFDLKDLKRYKKDSFYWYKKVIEENGNNL
HHHHCCCHHHHCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRHSKLKDFPKDFLWSASTSAYQVEGAWNEDGKGMSVQDAKTSLPEGTSDFKVASDHYHH
CCCCCCHHCCHHHHHCCCCCEEEEECCCCCCCCCCEECHHHHCCCCCCCCCEECCHHHHH
FEEDIAFLGEMGLKAYRFSISWTRIIPDGDGKINTKGVQFYHKLIDACLSYNIEPIVTMY
HHHHHHHHHHCCCEEEEEEEEEEEEEECCCCEECCHHHHHHHHHHHHHHCCCCCEEEEEE
HFDLPFELEKKGGWNNRTTIDAFLKFSKILFEQYGSKVKYFLTINEQNMMILHGAAIGTS
EECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEEECCC
KGSGINIWKELYQQNHNMLVAQAKAMELCHKLCPNSKIGPAPNIASIYPASSKPEDYLAA
CCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHH
QNFTAIRNWLYLDMAVFGRYNSTAWSYLEEIDAVPKIEEGDMEILRNAKPDFIAFNYYNT
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEEEEE
ATVKANNDAKKVQDSSGDQQLAVFEAGVFEGVQNPNLEKTEFGWEIDPVGFRITLREVYD
EEEEECCCHHHHCCCCCCCEEEEEECHHHHCCCCCCCCCCCCCCEECCCCEEEEHHHHHH
RYNLPIIVTENGLGAFDKLEDGTVHDDYRIEYYKKHLHEIKEAITDGVKVFGYSPWSAID
HCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHH
LVSTHQGVTKRYGFIYVNRDEFDLKDLKRYKKDSFYWYKKVIEENGNNL
HHHHCCCHHHHCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]