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Identifier: 15004706

GI number: 15004706

Start: 43

End: 798

Strand: Direct

Name: Not Available

Synonym: CA_P0001

Alternate gene names: 15004706

Gene position: 43-798 (Clockwise)

Preceding gene: NA

Following gene: 15004707

Centisome position: 0.02

GC content: 28.31

Gene sequence:

>756_bases
ATGAAAGAATATAAATATACTGTTATTACAGGAGCAAGTTCAGGGATAGGATATGAGGCTGCAAAGGCATTTGCAAAAAG
AGGAAAAAATTTAATTATTATTGCTAGAAGAAGAGAAAAATTAGAAGAGTTAAAAAAGGAAATCTTACATTATAATAGAT
CATTAAAGGTAATAGTTAAAAGTATTGATTTGTCAATTACATCTAATGTATATAGTTTATATGATGAGCTTAAAAATTAT
AATATTGAAACTTTAGTAAATAACGCTGGGTTTGGCGATTATAGCAAAGTAAATAATCAAAATTTAGAAAAGGTTGAGTC
TATGCTTAGCTTAAATATAGAAGCATTAGTGATTTTATCATCATTATTTGTACGTGACTATGAGAAAATTGAAGGTACAC
AGCTTATAAATATTTCATCCGCAGGAGGATACACAATTGTACCAAATGCTGTTATATACTGTGCAACCAAATTTTTTGTA
AGTTCGTTTACAGAAGGATTAGCTAGGGAACTTATAGAGGCTAAATCTAATTTAAAAGCGAAGGTATTGGCACCAGCAGC
AACTGAAACAGAATTTGGTAAAGTAGCAAGTGATGTAAAAGAATATGATTATCAAGAGAAATTTCATAAATATCACACAT
CAAAACAAATGGCAGAGTTTTTAATTAAATTATATGATAATGATTATATCGTTGGTAAGGTAGATAGAAACAGTTTTAAG
TTCACACTACAAAATCCAATTTTTGATTATGCTTAA

Upstream 100 bases:

>100_bases
GAATAGTACAATTTAAAAACCTCCTTTATAATGCTTGACCTAGAGTTAACTCTAACTCGATTGTATAATGCAATTATAGC
ATATTTAGGAGGTATTTAAA

Downstream 100 bases:

>100_bases
AAGGTAAATGTAATCTATAACTGTATATAAGGTTACTTTAAATATTAGTATTAGGTATTAGGGTTTAGTACTTATTATAA
CCCTAATACTTAATACTAAT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKEYKYTVITGASSGIGYEAAKAFAKRGKNLIIIARRREKLEELKKEILHYNRSLKVIVKSIDLSITSNVYSLYDELKNY
NIETLVNNAGFGDYSKVNNQNLEKVESMLSLNIEALVILSSLFVRDYEKIEGTQLINISSAGGYTIVPNAVIYCATKFFV
SSFTEGLARELIEAKSNLKAKVLAPAATETEFGKVASDVKEYDYQEKFHKYHTSKQMAEFLIKLYDNDYIVGKVDRNSFK
FTLQNPIFDYA

Sequences:

>Translated_251_residues
MKEYKYTVITGASSGIGYEAAKAFAKRGKNLIIIARRREKLEELKKEILHYNRSLKVIVKSIDLSITSNVYSLYDELKNY
NIETLVNNAGFGDYSKVNNQNLEKVESMLSLNIEALVILSSLFVRDYEKIEGTQLINISSAGGYTIVPNAVIYCATKFFV
SSFTEGLARELIEAKSNLKAKVLAPAATETEFGKVASDVKEYDYQEKFHKYHTSKQMAEFLIKLYDNDYIVGKVDRNSFK
FTLQNPIFDYA
>Mature_251_residues
MKEYKYTVITGASSGIGYEAAKAFAKRGKNLIIIARRREKLEELKKEILHYNRSLKVIVKSIDLSITSNVYSLYDELKNY
NIETLVNNAGFGDYSKVNNQNLEKVESMLSLNIEALVILSSLFVRDYEKIEGTQLINISSAGGYTIVPNAVIYCATKFFV
SSFTEGLARELIEAKSNLKAKVLAPAATETEFGKVASDVKEYDYQEKFHKYHTSKQMAEFLIKLYDNDYIVGKVDRNSFK
FTLQNPIFDYA

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=194, Percent_Identity=28.3505154639175, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7705855, Length=178, Percent_Identity=29.7752808988764, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7706318, Length=227, Percent_Identity=27.7533039647577, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4557649, Length=194, Percent_Identity=31.9587628865979, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI226371731, Length=175, Percent_Identity=29.1428571428571, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=24.1106719367589, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787820, Length=169, Percent_Identity=28.9940828402367, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=218, Percent_Identity=27.0642201834862, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=215, Percent_Identity=26.9767441860465, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25152911, Length=196, Percent_Identity=28.0612244897959, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=28.7937743190661, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17557668, Length=171, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=226, Percent_Identity=29.2035398230088, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17532725, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=225, Percent_Identity=27.1111111111111, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=202, Percent_Identity=28.7128712871287, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17559552, Length=171, Percent_Identity=28.6549707602339, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=216, Percent_Identity=25.462962962963, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=199, Percent_Identity=29.6482412060301, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=175, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=35.0253807106599, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319635, Length=185, Percent_Identity=32.4324324324324, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=29.6482412060301, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=29.6482412060301, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24580925, Length=192, Percent_Identity=31.7708333333333, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24584752, Length=168, Percent_Identity=31.547619047619, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=192, Percent_Identity=29.6875, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=30, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007238, Length=189, Percent_Identity=29.1005291005291, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640442, Length=183, Percent_Identity=31.1475409836066, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=26.8518518518519, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281364494, Length=199, Percent_Identity=29.1457286432161, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28508; Mature: 28508

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYKYTVITGASSGIGYEAAKAFAKRGKNLIIIARRREKLEELKKEILHYNRSLKVIVK
CCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHH
SIDLSITSNVYSLYDELKNYNIETLVNNAGFGDYSKVNNQNLEKVESMLSLNIEALVILS
HHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCHHCCCCCHHHHHHHHHCCHHHHHHHH
SLFVRDYEKIEGTQLINISSAGGYTIVPNAVIYCATKFFVSSFTEGLARELIEAKSNLKA
HHHHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
KVLAPAATETEFGKVASDVKEYDYQEKFHKYHTSKQMAEFLIKLYDNDYIVGKVDRNSFK
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEE
FTLQNPIFDYA
EEECCCCCCCC
>Mature Secondary Structure
MKEYKYTVITGASSGIGYEAAKAFAKRGKNLIIIARRREKLEELKKEILHYNRSLKVIVK
CCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHH
SIDLSITSNVYSLYDELKNYNIETLVNNAGFGDYSKVNNQNLEKVESMLSLNIEALVILS
HHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCHHCCCCCHHHHHHHHHCCHHHHHHHH
SLFVRDYEKIEGTQLINISSAGGYTIVPNAVIYCATKFFVSSFTEGLARELIEAKSNLKA
HHHHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
KVLAPAATETEFGKVASDVKEYDYQEKFHKYHTSKQMAEFLIKLYDNDYIVGKVDRNSFK
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEE
FTLQNPIFDYA
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA