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The map label for this gene is atsA [H]

Identifier: 150010480

GI number: 150010480

Start: 4750531

End: 4752126

Strand: Direct

Name: atsA [H]

Synonym: BDI_3921

Alternate gene names: 150010480

Gene position: 4750531-4752126 (Clockwise)

Preceding gene: 150010479

Following gene: 150010481

Centisome position: 98.74

GC content: 40.91

Gene sequence:

>1596_bases
ATGAAAAATACTATTAATTATGGAGCTATATTAGCCCCTGCCCTTTTGTTCTCCGCATGCGGAACAGGGCAAAAAGAAGT
GGCAGAGAAGCCGCTCAATATCATTCATATCATGACGGATGATCATTCGTATCAAACTATTAGCGCTTATGGACATGCGC
TAGGTAAATTGGCTCCTACACCAAATTTAGATCGTTTGGCTGCGGAAGGTATGTTATTCAGGCAAGCCTTTGTAGAGAAT
TCTCTGTCTACTCCTAGCCGTGCTTGTTTGATGACCGGTCTTTACAGTCACCAAAACGGACAAAGACAGTTAGGAAAAGG
TATTGATACGACAAAAGTATTCTTCTCTGAAATCTTACAACAGCACGGTTATCAGACAGGTGTTGTCGGTAAATGGCATA
TGCAATGTGAGCCGAAAGGTTTTGATTATTATCATGTGTTATGGGATCAAGGAGATTATTATAATCCGGAGTTCAAAAGT
AAAGAATCGAATGGCAAGTATGTAAAAGAAGAGGGATATGCGACGACCCTTACGACCGATCACGCTATCGAGTTTTTGGA
AGAGAGGGATAAGGATAAGCCTTTCTGCCTGCTGGTTCATCATAAGGCTCCACATCGTAACTGGATGCCGGATACGAAAT
ATATGGATTTATATGAGGATGTAGAGTTCCCATATCCAGATACTTTCAATGATAATTATGCCACTCGTTGCGATGCCGCA
CGTACACAAGAGATGAGTATAGACAAAAATATGACTTTGGTTTATGATTTGAAGGTAGATGAGCTTAAAGATAAGGAGGC
TTATAAAAAGGAATGGAATATTGATGGTTGGCAGGCCTCTTTGGATCGTATGACCCCGGAACAACGGGAGGCTTGGATCG
CTTCTTATAAGCCTCGTAACGAAAAATTCATTAACGAGAACCTGAAAGGTGAGGATTTGGTTAAATGGAAATATCAACGT
TATATCAAGGATTACGTACGTTGCATCAAATCTATTGACGATGAGGTGGGACGTTTGATCGCCTATCTGGAAAAAGAAGG
ACTTATGGATAATACCGTGATCGTTTATACCTCGGATCAAGGTTTTTACATGGGTGAACATGGGTGGTTCGACAAACGTT
TCATGTATGAGGAATCTTTCCGTACGCCGTTGATTATCCGTTATCCTGCTAAAATCAAGGCGGGAAGTGAATGTACAGCC
TTAGTACAGAACATTGACTATGCCCCAACTTATCTGGATATAGCCGGTATCGAGAAACCTGATTATATGGTAGGAACTTC
TTTAGTTCCCTTGTTTGGAGGCGAGACACCAAAAGATTGGCGCAAGTATCTGTATTATCATTATTATGATTATCCAGCTA
TCCATATGGTACGTCGTCACGATGGCGTGCGTGACAGTCGTTATAAATTGATCCATTTCTATGGAGAGAAGAATGAGCAT
AATGACGCGATTAATTGCAACGAGCTTTACGATTTGCAAAGTGATCCGAATGAGCTGAATAATTTATACGATAATCCGGA
ATATGCTGATATCCAAACTCGCCTGCAAGCACGTTTGGATAAGTTCCGTGTAGACCAGAAAGTTGACGAATATTAA

Upstream 100 bases:

>100_bases
ACAATCTATAGCAGAAGAGGCTCGGTTGGATCTGGGAGATGATCTCACGGGACAAATAGGTTTGAATCGTCGGGAAGTAG
GTTACATAAAATAATTATAT

Downstream 100 bases:

>100_bases
GGTGCTAACTCTGTAAAATCATTTATTTTGTGTAAGTTTGGCGGATAGAAAGAATCATTCACCTAAAATACGATTGTGAA
ATGAAACTCAATTTATCCGC

Product: mucin-desulfating sulfatase MdsA

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MKNTINYGAILAPALLFSACGTGQKEVAEKPLNIIHIMTDDHSYQTISAYGHALGKLAPTPNLDRLAAEGMLFRQAFVEN
SLSTPSRACLMTGLYSHQNGQRQLGKGIDTTKVFFSEILQQHGYQTGVVGKWHMQCEPKGFDYYHVLWDQGDYYNPEFKS
KESNGKYVKEEGYATTLTTDHAIEFLEERDKDKPFCLLVHHKAPHRNWMPDTKYMDLYEDVEFPYPDTFNDNYATRCDAA
RTQEMSIDKNMTLVYDLKVDELKDKEAYKKEWNIDGWQASLDRMTPEQREAWIASYKPRNEKFINENLKGEDLVKWKYQR
YIKDYVRCIKSIDDEVGRLIAYLEKEGLMDNTVIVYTSDQGFYMGEHGWFDKRFMYEESFRTPLIIRYPAKIKAGSECTA
LVQNIDYAPTYLDIAGIEKPDYMVGTSLVPLFGGETPKDWRKYLYYHYYDYPAIHMVRRHDGVRDSRYKLIHFYGEKNEH
NDAINCNELYDLQSDPNELNNLYDNPEYADIQTRLQARLDKFRVDQKVDEY

Sequences:

>Translated_531_residues
MKNTINYGAILAPALLFSACGTGQKEVAEKPLNIIHIMTDDHSYQTISAYGHALGKLAPTPNLDRLAAEGMLFRQAFVEN
SLSTPSRACLMTGLYSHQNGQRQLGKGIDTTKVFFSEILQQHGYQTGVVGKWHMQCEPKGFDYYHVLWDQGDYYNPEFKS
KESNGKYVKEEGYATTLTTDHAIEFLEERDKDKPFCLLVHHKAPHRNWMPDTKYMDLYEDVEFPYPDTFNDNYATRCDAA
RTQEMSIDKNMTLVYDLKVDELKDKEAYKKEWNIDGWQASLDRMTPEQREAWIASYKPRNEKFINENLKGEDLVKWKYQR
YIKDYVRCIKSIDDEVGRLIAYLEKEGLMDNTVIVYTSDQGFYMGEHGWFDKRFMYEESFRTPLIIRYPAKIKAGSECTA
LVQNIDYAPTYLDIAGIEKPDYMVGTSLVPLFGGETPKDWRKYLYYHYYDYPAIHMVRRHDGVRDSRYKLIHFYGEKNEH
NDAINCNELYDLQSDPNELNNLYDNPEYADIQTRLQARLDKFRVDQKVDEY
>Mature_531_residues
MKNTINYGAILAPALLFSACGTGQKEVAEKPLNIIHIMTDDHSYQTISAYGHALGKLAPTPNLDRLAAEGMLFRQAFVEN
SLSTPSRACLMTGLYSHQNGQRQLGKGIDTTKVFFSEILQQHGYQTGVVGKWHMQCEPKGFDYYHVLWDQGDYYNPEFKS
KESNGKYVKEEGYATTLTTDHAIEFLEERDKDKPFCLLVHHKAPHRNWMPDTKYMDLYEDVEFPYPDTFNDNYATRCDAA
RTQEMSIDKNMTLVYDLKVDELKDKEAYKKEWNIDGWQASLDRMTPEQREAWIASYKPRNEKFINENLKGEDLVKWKYQR
YIKDYVRCIKSIDDEVGRLIAYLEKEGLMDNTVIVYTSDQGFYMGEHGWFDKRFMYEESFRTPLIIRYPAKIKAGSECTA
LVQNIDYAPTYLDIAGIEKPDYMVGTSLVPLFGGETPKDWRKYLYYHYYDYPAIHMVRRHDGVRDSRYKLIHFYGEKNEH
NDAINCNELYDLQSDPNELNNLYDNPEYADIQTRLQARLDKFRVDQKVDEY

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI157266309, Length=563, Percent_Identity=24.3339253996448, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI58743319, Length=542, Percent_Identity=24.9077490774908, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI4503899, Length=280, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI39930577, Length=211, Percent_Identity=33.175355450237, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4504061, Length=179, Percent_Identity=32.4022346368715, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI71852586, Length=140, Percent_Identity=38.5714285714286, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI189571643, Length=115, Percent_Identity=38.2608695652174, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI189571641, Length=115, Percent_Identity=38.2608695652174, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI189571638, Length=115, Percent_Identity=38.2608695652174, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI189571636, Length=115, Percent_Identity=38.2608695652174, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI71852584, Length=140, Percent_Identity=38.5714285714286, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI146229331, Length=117, Percent_Identity=39.3162393162393, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI146229329, Length=117, Percent_Identity=39.3162393162393, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI6005990, Length=117, Percent_Identity=39.3162393162393, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI146229324, Length=117, Percent_Identity=39.3162393162393, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI240255478, Length=113, Percent_Identity=38.9380530973451, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI240255483, Length=113, Percent_Identity=38.9380530973451, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI29789100, Length=113, Percent_Identity=38.9380530973451, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4506919, Length=182, Percent_Identity=32.4175824175824, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI53831991, Length=156, Percent_Identity=32.6923076923077, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI45430057, Length=151, Percent_Identity=33.112582781457, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI31742482, Length=140, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI38569405, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI38569407, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI59797060, Length=197, Percent_Identity=29.9492385786802, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI109389362, Length=214, Percent_Identity=26.1682242990654, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790112, Length=237, Percent_Identity=29.535864978903, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081924, Length=221, Percent_Identity=29.8642533936652, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790233, Length=240, Percent_Identity=26.25, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559078, Length=110, Percent_Identity=37.2727272727273, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17568795, Length=232, Percent_Identity=25.4310344827586, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533416, Length=222, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115533418, Length=182, Percent_Identity=29.6703296703297, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24653364, Length=436, Percent_Identity=25.6880733944954, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19922168, Length=436, Percent_Identity=25, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24647401, Length=108, Percent_Identity=39.8148148148148, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281366397, Length=227, Percent_Identity=29.5154185022026, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281366395, Length=227, Percent_Identity=29.5154185022026, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24666163, Length=227, Percent_Identity=29.5154185022026, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24666175, Length=229, Percent_Identity=30.5676855895196, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666109, Length=209, Percent_Identity=29.1866028708134, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356831, Length=238, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363223, Length=217, Percent_Identity=27.1889400921659, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 62144; Mature: 62144

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTINYGAILAPALLFSACGTGQKEVAEKPLNIIHIMTDDHSYQTISAYGHALGKLAPT
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCCC
PNLDRLAAEGMLFRQAFVENSLSTPSRACLMTGLYSHQNGQRQLGKGIDTTKVFFSEILQ
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHH
QHGYQTGVVGKWHMQCEPKGFDYYHVLWDQGDYYNPEFKSKESNGKYVKEEGYATTLTTD
HCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCCEEEEEHH
HAIEFLEERDKDKPFCLLVHHKAPHRNWMPDTKYMDLYEDVEFPYPDTFNDNYATRCDAA
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCH
RTQEMSIDKNMTLVYDLKVDELKDKEAYKKEWNIDGWQASLDRMTPEQREAWIASYKPRN
HHHHCCCCCCCEEEEEEEHHHHCCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCCC
EKFINENLKGEDLVKWKYQRYIKDYVRCIKSIDDEVGRLIAYLEKEGLMDNTVIVYTSDQ
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
GFYMGEHGWFDKRFMYEESFRTPLIIRYPAKIKAGSECTALVQNIDYAPTYLDIAGIEKP
CEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCC
DYMVGTSLVPLFGGETPKDWRKYLYYHYYDYPAIHMVRRHDGVRDSRYKLIHFYGEKNEH
CEEECCCEEECCCCCCCHHHHHEEEEEEECCCHHHHHHHCCCCCCCCEEEEEEECCCCCC
NDAINCNELYDLQSDPNELNNLYDNPEYADIQTRLQARLDKFRVDQKVDEY
CCCCCHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNTINYGAILAPALLFSACGTGQKEVAEKPLNIIHIMTDDHSYQTISAYGHALGKLAPT
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCCC
PNLDRLAAEGMLFRQAFVENSLSTPSRACLMTGLYSHQNGQRQLGKGIDTTKVFFSEILQ
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHH
QHGYQTGVVGKWHMQCEPKGFDYYHVLWDQGDYYNPEFKSKESNGKYVKEEGYATTLTTD
HCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCCEEEEEHH
HAIEFLEERDKDKPFCLLVHHKAPHRNWMPDTKYMDLYEDVEFPYPDTFNDNYATRCDAA
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCH
RTQEMSIDKNMTLVYDLKVDELKDKEAYKKEWNIDGWQASLDRMTPEQREAWIASYKPRN
HHHHCCCCCCCEEEEEEEHHHHCCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCCC
EKFINENLKGEDLVKWKYQRYIKDYVRCIKSIDDEVGRLIAYLEKEGLMDNTVIVYTSDQ
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
GFYMGEHGWFDKRFMYEESFRTPLIIRYPAKIKAGSECTALVQNIDYAPTYLDIAGIEKP
CEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCC
DYMVGTSLVPLFGGETPKDWRKYLYYHYYDYPAIHMVRRHDGVRDSRYKLIHFYGEKNEH
CEEECCCEEECCCCCCCHHHHHEEEEEEECCCHHHHHHHCCCCCCCCEEEEEEECCCCCC
NDAINCNELYDLQSDPNELNNLYDNPEYADIQTRLQARLDKFRVDQKVDEY
CCCCCHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]