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The map label for this gene is hutI

Identifier: 150010223

GI number: 150010223

Start: 4455384

End: 4456634

Strand: Direct

Name: hutI

Synonym: BDI_3646

Alternate gene names: 150010223

Gene position: 4455384-4456634 (Clockwise)

Preceding gene: 150010222

Following gene: 150010224

Centisome position: 92.6

GC content: 48.6

Gene sequence:

>1251_bases
ATGGAGAATAGCAAGATATTAATCAGGAATGCTGCCCAGATCGTCACTTGCCATGGGGATAAGGCGCGACGGGGAGCGGA
GATGTCTGATTTAGGCGTTATCGAGGATGGAGCCGTAGCGATGTCTGATGGGGTTATTACGCATGTAGGACCTACGGAGG
AGGTACTTCGAAACATCCATGCGGAGGATTATTTGGAGATTCGGGCGGAGAACCAAGCGGTGTTACCCGGATTTGTAGAT
AGCCATACGCATTTTATCTTTGGCGGTTACCGGGAGGAGGAGTTCTCTTGGCGATTGCGGGGAGATAGTTATATGTCGAT
CATGGAGCGTGGTGGAGGTATCGTGAATACGATGAAAGCTACCCGTGAAAGTGATTTCGATACACTATGGGACAGAGGGG
AAGAACGTTTGGATGAGTTATTCTCCATGGGTGTTACCACAGTGGAAGGGAAAAGTGGTTATGGTTTGGATTTGCAAACA
GAATTAGTTCAGCTTCGTGTCATGTCGGACCTGAATGAGTCTCATCCGATGGATGTCGTATCGACCTTTTTGGGAGCTCA
TGCTGTTCCTCCTGAATTTGCCGGTCGTACGGACGATTATGTGGATTATATGATCGAGGAAGTTCTTCCTGCCATACGAG
CCGAACATACGGTTACATTTTGTGATGTGTTTTGTGAGAAAGGCGTTTTCTCGTTAGAACAGAGTGAGCGCTTGCTTCGT
GCCGCCCGTCATCATCGTTTTAAATTGAAGATGCATGCGGATGAGATCGTTCCTTTCGGAGGGGCGGAACTGGCGGCCTC
CTTGAAGTGTGTAAGTGCTGATCATTTGTTACATATATCGGACACAGGCATCAAACGTCTGGCAAGAGCGGGTGTCGTAG
CTACCTTACTTCCGCTGACTGCCTTTTCCTTGAATGAGCCGTATGCGCCTGCAAGGAAGATGATAGATGCCGGTTGCGCG
GTGGCTTTAGCTTCCGATCTAAATCCAGGAAGTTGTTTCTCCGCCTCGATCCCGATGATGATAGCCTTGGCCTGTATCTA
TATGAAGATGACCCCTGAAGAAGCGGTAACGGCATTGACCATTAATGGAGCCGCAGCTGTGGGACGTGCCTCCGAGATTG
GAAGTATCAGCGTGGGAAAACGTGCGGACGTGATCTTGCTGAAATACCCGTCTTATAAGTTCCTACCTTATCATGTGGGA
ATGAATCTCGTGGATACCGTAATTAAGGACGGGGAACTTTATATGATGTAA

Upstream 100 bases:

>100_bases
GGTTCCTATGGAGGCGTTGATCGATACGGCCTCTTACTATTTGGGATTAGAGGACTTTTCTATGAATCAAGTATTGGAAG
CCCGTATTATGGAATAGCGT

Downstream 100 bases:

>100_bases
GATAAGAATTGTTGAATCATTTAAATCAAAATACTATGTTAGCAGACTTGACAATTAAAGATTTTTTGGCGGAAACGGCG
GGTAGTGCTCCCGTTCCCGG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MENSKILIRNAAQIVTCHGDKARRGAEMSDLGVIEDGAVAMSDGVITHVGPTEEVLRNIHAEDYLEIRAENQAVLPGFVD
SHTHFIFGGYREEEFSWRLRGDSYMSIMERGGGIVNTMKATRESDFDTLWDRGEERLDELFSMGVTTVEGKSGYGLDLQT
ELVQLRVMSDLNESHPMDVVSTFLGAHAVPPEFAGRTDDYVDYMIEEVLPAIRAEHTVTFCDVFCEKGVFSLEQSERLLR
AARHHRFKLKMHADEIVPFGGAELAASLKCVSADHLLHISDTGIKRLARAGVVATLLPLTAFSLNEPYAPARKMIDAGCA
VALASDLNPGSCFSASIPMMIALACIYMKMTPEEAVTALTINGAAAVGRASEIGSISVGKRADVILLKYPSYKFLPYHVG
MNLVDTVIKDGELYMM

Sequences:

>Translated_416_residues
MENSKILIRNAAQIVTCHGDKARRGAEMSDLGVIEDGAVAMSDGVITHVGPTEEVLRNIHAEDYLEIRAENQAVLPGFVD
SHTHFIFGGYREEEFSWRLRGDSYMSIMERGGGIVNTMKATRESDFDTLWDRGEERLDELFSMGVTTVEGKSGYGLDLQT
ELVQLRVMSDLNESHPMDVVSTFLGAHAVPPEFAGRTDDYVDYMIEEVLPAIRAEHTVTFCDVFCEKGVFSLEQSERLLR
AARHHRFKLKMHADEIVPFGGAELAASLKCVSADHLLHISDTGIKRLARAGVVATLLPLTAFSLNEPYAPARKMIDAGCA
VALASDLNPGSCFSASIPMMIALACIYMKMTPEEAVTALTINGAAAVGRASEIGSISVGKRADVILLKYPSYKFLPYHVG
MNLVDTVIKDGELYMM
>Mature_416_residues
MENSKILIRNAAQIVTCHGDKARRGAEMSDLGVIEDGAVAMSDGVITHVGPTEEVLRNIHAEDYLEIRAENQAVLPGFVD
SHTHFIFGGYREEEFSWRLRGDSYMSIMERGGGIVNTMKATRESDFDTLWDRGEERLDELFSMGVTTVEGKSGYGLDLQT
ELVQLRVMSDLNESHPMDVVSTFLGAHAVPPEFAGRTDDYVDYMIEEVLPAIRAEHTVTFCDVFCEKGVFSLEQSERLLR
AARHHRFKLKMHADEIVPFGGAELAASLKCVSADHLLHISDTGIKRLARAGVVATLLPLTAFSLNEPYAPARKMIDAGCA
VALASDLNPGSCFSASIPMMIALACIYMKMTPEEAVTALTINGAAAVGRASEIGSISVGKRADVILLKYPSYKFLPYHVG
MNLVDTVIKDGELYMM

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=421, Percent_Identity=38.0047505938242, Blast_Score=248, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI17555004, Length=444, Percent_Identity=34.6846846846847, Blast_Score=255, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_PARD8 (A6LI30)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001304966.1
- ProteinModelPortal:   A6LI30
- SMR:   A6LI30
- STRING:   A6LI30
- GeneID:   5308795
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_3646
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   ASHEIDA
- ProtClustDB:   PRK09356
- BioCyc:   PDIS435591:BDI_3646-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 45631; Mature: 45631

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: BINDING 91-91 BINDING 104-104 BINDING 154-154 BINDING 187-187 BINDING 255-255

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSKILIRNAAQIVTCHGDKARRGAEMSDLGVIEDGAVAMSDGVITHVGPTEEVLRNIH
CCCCCEEEECCEEEEEECCCHHHCCCCCHHCCEECCCCEEECCCEEEECCCHHHHHHHCC
AEDYLEIRAENQAVLPGFVDSHTHFIFGGYREEEFSWRLRGDSYMSIMERGGGIVNTMKA
CHHEEEEECCCCEECCCCCCCCCEEEECCEECCCCEEEECCCHHHHHHHHCCCEEEHHHH
TRESDFDTLWDRGEERLDELFSMGVTTVEGKSGYGLDLQTELVQLRVMSDLNESHPMDVV
HCCCCHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
STFLGAHAVPPEFAGRTDDYVDYMIEEVLPAIRAEHTVTFCDVFCEKGVFSLEQSERLLR
HHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
AARHHRFKLKMHADEIVPFGGAELAASLKCVSADHLLHISDTGIKRLARAGVVATLLPLT
HHHCCEEEEEECHHHCCCCCCHHHHHHHEEECCCCEEEECCHHHHHHHHHHHHHHHHHHH
AFSLNEPYAPARKMIDAGCAVALASDLNPGSCFSASIPMMIALACIYMKMTPEEAVTALT
HHCCCCCCHHHHHHHHCCHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEE
INGAAAVGRASEIGSISVGKRADVILLKYPSYKFLPYHVGMNLVDTVIKDGELYMM
ECCHHHCCCCCCCCCEECCCCCCEEEEECCCCEEEHHHHCHHHHHHHHCCCCEEEC
>Mature Secondary Structure
MENSKILIRNAAQIVTCHGDKARRGAEMSDLGVIEDGAVAMSDGVITHVGPTEEVLRNIH
CCCCCEEEECCEEEEEECCCHHHCCCCCHHCCEECCCCEEECCCEEEECCCHHHHHHHCC
AEDYLEIRAENQAVLPGFVDSHTHFIFGGYREEEFSWRLRGDSYMSIMERGGGIVNTMKA
CHHEEEEECCCCEECCCCCCCCCEEEECCEECCCCEEEECCCHHHHHHHHCCCEEEHHHH
TRESDFDTLWDRGEERLDELFSMGVTTVEGKSGYGLDLQTELVQLRVMSDLNESHPMDVV
HCCCCHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
STFLGAHAVPPEFAGRTDDYVDYMIEEVLPAIRAEHTVTFCDVFCEKGVFSLEQSERLLR
HHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
AARHHRFKLKMHADEIVPFGGAELAASLKCVSADHLLHISDTGIKRLARAGVVATLLPLT
HHHCCEEEEEECHHHCCCCCCHHHHHHHEEECCCCEEEECCHHHHHHHHHHHHHHHHHHH
AFSLNEPYAPARKMIDAGCAVALASDLNPGSCFSASIPMMIALACIYMKMTPEEAVTALT
HHCCCCCCHHHHHHHHCCHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEE
INGAAAVGRASEIGSISVGKRADVILLKYPSYKFLPYHVGMNLVDTVIKDGELYMM
ECCHHHCCCCCCCCCEECCCCCCEEEEECCCCEEEHHHHCHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA