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The map label for this gene is glcK [H]

Identifier: 150010166

GI number: 150010166

Start: 4396812

End: 4397798

Strand: Direct

Name: glcK [H]

Synonym: BDI_3589

Alternate gene names: 150010166

Gene position: 4396812-4397798 (Clockwise)

Preceding gene: 150010165

Following gene: 150010167

Centisome position: 91.38

GC content: 45.8

Gene sequence:

>987_bases
ATGGAGAAGCCTTATGTAGTAGGTATCGATATAGGTGGTACCAACACTGTTTTTGGTGTAGTTGACGCAAGAGGAACAAT
CTTGTATAGTGGATCAATTAAGACTGGTAAATATGCAGACGTTAATGACTATGTAGCGGAATTAGCTAAAGGTCTGAAGT
CTGTTATTGATCAGGCTGGTGGTCCGGATAAGATTAAAGGTGTGGGTGTAGGTGCTCCGAACGGAAACTTTTTCAACGGA
TGTATCGAATTCGCTCCGAACTTGCCTTGGAAAGGTAAGATTCCTTTGGCTCAATTGATCAGCGAACAGATTGATGGTAT
TCCTGTTGCTTTAACAAACGACGCCAATGCTGCCGCTATCGGTGAGATGACTTATGGAGCCGCTCGCGGTATGAAAGATT
TTATCGTGATCACTTTGGGTACCGGCGTGGGTAGCGGTATCGTAGTAGGTGGTAACTTGGTATACGGACATGACGGTTTT
GCCGGTGAGTTGGGCCATGTTATCATGCGTCGTAACAACGGTCGTCAGTGTGGTTGCGGTCGTCAAGGATGTCTGGAGGC
TTATGCTTCAGCTACCGGTGTGGCTCGTACGGCTCGTGAATATCTGGAAATCCGTAAGGACGAGAGTGTTCTTCGCGACT
TGGATCCGGATGAAATCACTTCAAAAGACGTATACGACGCAGCTATGAAGAATGATAAGATCGCTCTTGAGATTTTCGAG
GCTACCGGCTCTATGTTGGGAGAGGCTTTCGCTGATTTCGTAGCATTCTCTAGCCCGGAGGCTATCATTTTGTTTGGCGG
TCTTACGAAAGCTGGCGATTTGATCATGAACCCGATTAAACGTTCAATGGAGAAAAATATGTTGAAGGTTTACGCAGGTA
AGACTAAATTATTATTCTCTCAATTGAAAGAGAGCGACGCTGCCGTATTAGGAGCAAGTGCTTTGGGTTGGGAAGTAAGA
GACCAAAGCGCTGGTTTGGAAGTCTAA

Upstream 100 bases:

>100_bases
TCTGTAAAATTTTCTTCAAATCGTATTGCAACTTGTGTTAAACCTCTTATATTTGCTACCTAGAAAGAGGAAAATCATTA
TTAATCCTAAATATAAAATC

Downstream 100 bases:

>100_bases
ATCCGGTTTTACGTATAACGAAAAGACATTTGCGAAATAAGGCAAGCCGCATCTATATTTAGGTGCGGCTTGTTGTTTTT
AATTGAATTATAAATCATAA

Product: putative transcriptional repressor

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MEKPYVVGIDIGGTNTVFGVVDARGTILYSGSIKTGKYADVNDYVAELAKGLKSVIDQAGGPDKIKGVGVGAPNGNFFNG
CIEFAPNLPWKGKIPLAQLISEQIDGIPVALTNDANAAAIGEMTYGAARGMKDFIVITLGTGVGSGIVVGGNLVYGHDGF
AGELGHVIMRRNNGRQCGCGRQGCLEAYASATGVARTAREYLEIRKDESVLRDLDPDEITSKDVYDAAMKNDKIALEIFE
ATGSMLGEAFADFVAFSSPEAIILFGGLTKAGDLIMNPIKRSMEKNMLKVYAGKTKLLFSQLKESDAAVLGASALGWEVR
DQSAGLEV

Sequences:

>Translated_328_residues
MEKPYVVGIDIGGTNTVFGVVDARGTILYSGSIKTGKYADVNDYVAELAKGLKSVIDQAGGPDKIKGVGVGAPNGNFFNG
CIEFAPNLPWKGKIPLAQLISEQIDGIPVALTNDANAAAIGEMTYGAARGMKDFIVITLGTGVGSGIVVGGNLVYGHDGF
AGELGHVIMRRNNGRQCGCGRQGCLEAYASATGVARTAREYLEIRKDESVLRDLDPDEITSKDVYDAAMKNDKIALEIFE
ATGSMLGEAFADFVAFSSPEAIILFGGLTKAGDLIMNPIKRSMEKNMLKVYAGKTKLLFSQLKESDAAVLGASALGWEVR
DQSAGLEV
>Mature_328_residues
MEKPYVVGIDIGGTNTVFGVVDARGTILYSGSIKTGKYADVNDYVAELAKGLKSVIDQAGGPDKIKGVGVGAPNGNFFNG
CIEFAPNLPWKGKIPLAQLISEQIDGIPVALTNDANAAAIGEMTYGAARGMKDFIVITLGTGVGSGIVVGGNLVYGHDGF
AGELGHVIMRRNNGRQCGCGRQGCLEAYASATGVARTAREYLEIRKDESVLRDLDPDEITSKDVYDAAMKNDKIALEIFE
ATGSMLGEAFADFVAFSSPEAIILFGGLTKAGDLIMNPIKRSMEKNMLKVYAGKTKLLFSQLKESDAAVLGASALGWEVR
DQSAGLEV

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=284, Percent_Identity=28.169014084507, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4885285, Length=284, Percent_Identity=28.169014084507, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI298566325, Length=284, Percent_Identity=28.169014084507, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI190014632, Length=284, Percent_Identity=28.169014084507, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1787878, Length=224, Percent_Identity=27.6785714285714, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786891, Length=203, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081733, Length=321, Percent_Identity=25.5451713395639, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082127, Length=203, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787363, Length=295, Percent_Identity=27.4576271186441, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34572; Mature: 34572

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPYVVGIDIGGTNTVFGVVDARGTILYSGSIKTGKYADVNDYVAELAKGLKSVIDQAG
CCCCEEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GPDKIKGVGVGAPNGNFFNGCIEFAPNLPWKGKIPLAQLISEQIDGIPVALTNDANAAAI
CCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCEEE
GEMTYGAARGMKDFIVITLGTGVGSGIVVGGNLVYGHDGFAGELGHVIMRRNNGRQCGCG
HHHHHHHHCCCCEEEEEEECCCCCCCEEECCEEEECCCCCHHHHHHEEEECCCCCCCCCC
RQGCLEAYASATGVARTAREYLEIRKDESVLRDLDPDEITSKDVYDAAMKNDKIALEIFE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCHHHHHHHHCCCCEEEEEEH
ATGSMLGEAFADFVAFSSPEAIILFGGLTKAGDLIMNPIKRSMEKNMLKVYAGKTKLLFS
HHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QLKESDAAVLGASALGWEVRDQSAGLEV
HHHHCCHHEEEHHHHCCEECCCCCCCCC
>Mature Secondary Structure
MEKPYVVGIDIGGTNTVFGVVDARGTILYSGSIKTGKYADVNDYVAELAKGLKSVIDQAG
CCCCEEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GPDKIKGVGVGAPNGNFFNGCIEFAPNLPWKGKIPLAQLISEQIDGIPVALTNDANAAAI
CCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCEEE
GEMTYGAARGMKDFIVITLGTGVGSGIVVGGNLVYGHDGFAGELGHVIMRRNNGRQCGCG
HHHHHHHHCCCCEEEEEEECCCCCCCEEECCEEEECCCCCHHHHHHEEEECCCCCCCCCC
RQGCLEAYASATGVARTAREYLEIRKDESVLRDLDPDEITSKDVYDAAMKNDKIALEIFE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCHHHHHHHHCCCCEEEEEEH
ATGSMLGEAFADFVAFSSPEAIILFGGLTKAGDLIMNPIKRSMEKNMLKVYAGKTKLLFS
HHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QLKESDAAVLGASALGWEVRDQSAGLEV
HHHHCCHHEEEHHHHCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]