| Definition | Parabacteroides distasonis ATCC 8503 chromosome, complete genome. |
|---|---|
| Accession | NC_009615 |
| Length | 4,811,379 |
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The map label for this gene is parC [H]
Identifier: 150009781
GI number: 150009781
Start: 3867763
End: 3870498
Strand: Reverse
Name: parC [H]
Synonym: BDI_3197
Alternate gene names: 150009781
Gene position: 3870498-3867763 (Counterclockwise)
Preceding gene: 150009784
Following gene: 150009780
Centisome position: 80.44
GC content: 47.73
Gene sequence:
>2736_bases ATGAGACCGGAAGATAAAGAAGACGATTATATCGAGGATAAGGAAAACGAGGAAATTGAGGATATAAATAGTGATACCCA AGATAACGAGGCTACGGAGGAAGAGGCGAATACCCATTCCGACTATAAAGTCCCGGGGAAAGGGGATACACGTGTCACGA CCTATCATTTGTCTGGGATGTACCAAAACTGGTTCCTAGACTACGCTTCTTATGTGATCTTGGAACGGGCCGTTCCGCAT ATCAACGATGGACTGAAACCCGTACAACGACGTATCCTGCACTCCATGAGAAGGTTGGATGACGGGCGGTATAACAAGGT TGCGAATATCGTAGGTCATACGATGCAGTTCCACCCTCACGGAGACGCCTCTATCGGAGATGCCTTGGTGCAATTGGGAC AAAAGGATCTATTGATCGATTGCCAAGGAAACTGGGGTAATATCCTGACGGGAGACGGAGCCGCCGCTCCTCGTTATATA GAGGCTCGCCTTTCCAAGTTTGCCTTGGAGACCGTATTCAATCCCAAGACAACCCTTTGGCAGCTTTCTTACGACGGGCG TAATAAGGAACCGGTTACCTTACCGGTAAAATTCCCTTTATTGCTGGCACAGGGCGTGGAAGGTATCGCCGTAGGCCTGT CTTCCAAGATACTCCCTCATAATTTCAATGAGTTATTAGATGCTTCCATCGCCTATCTACGGGGAGAGGAATTCGCGTTA TATCCGGATTTCCAGACAGGAGGCTCTATCGACATAGCCAAATATAATGATGGAGAACGGGGTGGATCGGTGAAAGTCCG TGCAAAAATCGGCAAGCTCGATAATAAGACATTGGTGATCTCGGAGATCCCGTATGGAAAAACAACCTCTACCGTGATCG AGTCCATCCTAAAAGCGAACGATAAAGGAAAGATCAAGATCAAGAAGGTAGACGATAATACCGCCAAGGATGTAGAGATC TTGGTGCATCTCGCTCCGGGGGTCTCTTCAGACAAGACCATCGATGCTTTATACGCCTTTACGGATTGTGAGATCAGTAT CTCCCCAAACTGTTGCGTGATCAAGGAGGACAAGCCGCATTTCCTTACGGTCAGCGATGTGCTCCACCACTCTACGGATC GTACGCTGGAGCTGTTACGGGAAGAACTCAAGATTCAGAAACAAGAACAAGAGGAGGCCCTGTTCTTCGCCTCCCTTGAA AAGATATTTATCGAGGAGCGCATCTATAAAGATCCGGAGTTCGAGAACGCCAAGAACATGGACGAGGCGATATCCCATAT CGACCTTCGTTTAGAGCCGTTCAAGCCCCGATTTATCCGTGAGGTTACCCGGGACGATATCCTGAAGCTCATGGAGATCA AAATGGGACGTATCCTAAAGTTCAACTCCGACAAGAGTAACGAGTTCATTGCCCAGACCTTGGAACAAATCGCCAAGATC AACGATAAACTGGAACATATCATCGACTATACTATCGATTGGTTTACCATGCTGAAAGAGAAATACGGCAAGGCTTACCC TCGCCATACCGTGATACGCAATTTCGACACGATCGAGGCGACCAAGGTCGTAGAGGCAAACGAGAAATTGTATATCAACC GTCAAGAAGGTTTCATCGGCATGGGACTGAAAAAGGACGAGTTCATATGTAACTGCTCGGATATAGACGATGTCATTATC TTCTATCGCAACGGTACTTATAAGATCGTCAAGGTAGCGGATAAGATCTTTATCGGTAAGGATATTCTATATGTCAACGT ATTTAAGCGTAACGACAACCGGACGATTTACAACGTCATATACCGGGACGGTAAGTTCGGATATAATTACATCAAACGCT TCGCCGTCACAGGCGCTACACGCGATCGGGAATACGACCTGACCAAAGGTACGGAAAACTCCCGTGTCCTTTACTTCAGC GCAAACCCGAACGGAGAGGCGGAGACCGTCAAGGTAATCCTGAAACCCAAACCCCGGCAGAAACTACTCGTCTTCGAAAA GAACTTCAGCGAGATAGCCATTAAGGGACGGGGTTCTCAAGGTAATATCCTGACGAAAGCGGAAGTGCACAAGATCAGCC TCAAGCAGAAAGGCTCTTCCACCTTGGGAGGCCGGGAAGTATGGTTCGACTGGGACGTACTCCGGTTAAATTACGATGGA CGGGGAGAAGAGCTAGGCGAGTTCCATAGCAACGATCAGATATTGGTGATCCTGCCGAACGGCGATTTCTACGTCACGAA TTTTGACCTTAGCAATCACTACGAGTCCAATATCATGGTCATCGAGAAATACCAGCCGAGCAAGATATGGACTGCCGTAT TATACGACGCGGATCAGAAATATTATTATATCAAACGATTCCTGCTGGAGGTAAACACCCGGAAGCAGAATTTCCTAGGA GAGAATCCGAAGAACCGCTTGATGTTGCTTACGGATGAGGTCTATCCTCGTATCGAGGTGATCTTCGGAGGCCATGACGC CTTCCGGGAGGCTCTCGTCCTCGATGCCGACGAATTTATCGCGGTGAAAGGCTTCAAAGCCAAAGGTAAACGAATCTCTA CATTTGAGGTCGAGACAATCAATGAGCTGGAACCGAATCGCTTCGTCCCTTCCGAAAACGCATCGGAATCAGACGATACC GAAGGCAATGAGGAGGAAAACGACACTGACGACGGGCAGAGTACCACGGATATTATCGATGAAATTACGGGACAGATGAA ATTGTTTGACGAATAA
Upstream 100 bases:
>100_bases CGTAAAAGCCTCATTCTTATAAAAACTGCCGAATATTTGCTATATTTACACCCTGTTAGCAATTTGGCGTAATAGCGTTG TGTAGAAAGAACTGGATTTT
Downstream 100 bases:
>100_bases CCTATGAAAGCTATCACCTGTTTGATTGGTTTGTTCCTGCTGTTTCTCGCGTCACCGGCCAAGGCCCAGTCCGATGGAGA CGAGATCCCTTGGTCTATCA
Product: DNA topoisomerase IV subunit A
Products: NA
Alternate protein names: Topoisomerase IV subunit A [H]
Number of amino acids: Translated: 911; Mature: 911
Protein sequence:
>911_residues MRPEDKEDDYIEDKENEEIEDINSDTQDNEATEEEANTHSDYKVPGKGDTRVTTYHLSGMYQNWFLDYASYVILERAVPH INDGLKPVQRRILHSMRRLDDGRYNKVANIVGHTMQFHPHGDASIGDALVQLGQKDLLIDCQGNWGNILTGDGAAAPRYI EARLSKFALETVFNPKTTLWQLSYDGRNKEPVTLPVKFPLLLAQGVEGIAVGLSSKILPHNFNELLDASIAYLRGEEFAL YPDFQTGGSIDIAKYNDGERGGSVKVRAKIGKLDNKTLVISEIPYGKTTSTVIESILKANDKGKIKIKKVDDNTAKDVEI LVHLAPGVSSDKTIDALYAFTDCEISISPNCCVIKEDKPHFLTVSDVLHHSTDRTLELLREELKIQKQEQEEALFFASLE KIFIEERIYKDPEFENAKNMDEAISHIDLRLEPFKPRFIREVTRDDILKLMEIKMGRILKFNSDKSNEFIAQTLEQIAKI NDKLEHIIDYTIDWFTMLKEKYGKAYPRHTVIRNFDTIEATKVVEANEKLYINRQEGFIGMGLKKDEFICNCSDIDDVII FYRNGTYKIVKVADKIFIGKDILYVNVFKRNDNRTIYNVIYRDGKFGYNYIKRFAVTGATRDREYDLTKGTENSRVLYFS ANPNGEAETVKVILKPKPRQKLLVFEKNFSEIAIKGRGSQGNILTKAEVHKISLKQKGSSTLGGREVWFDWDVLRLNYDG RGEELGEFHSNDQILVILPNGDFYVTNFDLSNHYESNIMVIEKYQPSKIWTAVLYDADQKYYYIKRFLLEVNTRKQNFLG ENPKNRLMLLTDEVYPRIEVIFGGHDAFREALVLDADEFIAVKGFKAKGKRISTFEVETINELEPNRFVPSENASESDDT EGNEEENDTDDGQSTTDIIDEITGQMKLFDE
Sequences:
>Translated_911_residues MRPEDKEDDYIEDKENEEIEDINSDTQDNEATEEEANTHSDYKVPGKGDTRVTTYHLSGMYQNWFLDYASYVILERAVPH INDGLKPVQRRILHSMRRLDDGRYNKVANIVGHTMQFHPHGDASIGDALVQLGQKDLLIDCQGNWGNILTGDGAAAPRYI EARLSKFALETVFNPKTTLWQLSYDGRNKEPVTLPVKFPLLLAQGVEGIAVGLSSKILPHNFNELLDASIAYLRGEEFAL YPDFQTGGSIDIAKYNDGERGGSVKVRAKIGKLDNKTLVISEIPYGKTTSTVIESILKANDKGKIKIKKVDDNTAKDVEI LVHLAPGVSSDKTIDALYAFTDCEISISPNCCVIKEDKPHFLTVSDVLHHSTDRTLELLREELKIQKQEQEEALFFASLE KIFIEERIYKDPEFENAKNMDEAISHIDLRLEPFKPRFIREVTRDDILKLMEIKMGRILKFNSDKSNEFIAQTLEQIAKI NDKLEHIIDYTIDWFTMLKEKYGKAYPRHTVIRNFDTIEATKVVEANEKLYINRQEGFIGMGLKKDEFICNCSDIDDVII FYRNGTYKIVKVADKIFIGKDILYVNVFKRNDNRTIYNVIYRDGKFGYNYIKRFAVTGATRDREYDLTKGTENSRVLYFS ANPNGEAETVKVILKPKPRQKLLVFEKNFSEIAIKGRGSQGNILTKAEVHKISLKQKGSSTLGGREVWFDWDVLRLNYDG RGEELGEFHSNDQILVILPNGDFYVTNFDLSNHYESNIMVIEKYQPSKIWTAVLYDADQKYYYIKRFLLEVNTRKQNFLG ENPKNRLMLLTDEVYPRIEVIFGGHDAFREALVLDADEFIAVKGFKAKGKRISTFEVETINELEPNRFVPSENASESDDT EGNEEENDTDDGQSTTDIIDEITGQMKLFDE >Mature_911_residues MRPEDKEDDYIEDKENEEIEDINSDTQDNEATEEEANTHSDYKVPGKGDTRVTTYHLSGMYQNWFLDYASYVILERAVPH INDGLKPVQRRILHSMRRLDDGRYNKVANIVGHTMQFHPHGDASIGDALVQLGQKDLLIDCQGNWGNILTGDGAAAPRYI EARLSKFALETVFNPKTTLWQLSYDGRNKEPVTLPVKFPLLLAQGVEGIAVGLSSKILPHNFNELLDASIAYLRGEEFAL YPDFQTGGSIDIAKYNDGERGGSVKVRAKIGKLDNKTLVISEIPYGKTTSTVIESILKANDKGKIKIKKVDDNTAKDVEI LVHLAPGVSSDKTIDALYAFTDCEISISPNCCVIKEDKPHFLTVSDVLHHSTDRTLELLREELKIQKQEQEEALFFASLE KIFIEERIYKDPEFENAKNMDEAISHIDLRLEPFKPRFIREVTRDDILKLMEIKMGRILKFNSDKSNEFIAQTLEQIAKI NDKLEHIIDYTIDWFTMLKEKYGKAYPRHTVIRNFDTIEATKVVEANEKLYINRQEGFIGMGLKKDEFICNCSDIDDVII FYRNGTYKIVKVADKIFIGKDILYVNVFKRNDNRTIYNVIYRDGKFGYNYIKRFAVTGATRDREYDLTKGTENSRVLYFS ANPNGEAETVKVILKPKPRQKLLVFEKNFSEIAIKGRGSQGNILTKAEVHKISLKQKGSSTLGGREVWFDWDVLRLNYDG RGEELGEFHSNDQILVILPNGDFYVTNFDLSNHYESNIMVIEKYQPSKIWTAVLYDADQKYYYIKRFLLEVNTRKQNFLG ENPKNRLMLLTDEVYPRIEVIFGGHDAFREALVLDADEFIAVKGFKAKGKRISTFEVETINELEPNRFVPSENASESDDT EGNEEENDTDDGQSTTDIIDEITGQMKLFDE
Specific function: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=236, Percent_Identity=31.7796610169492, Blast_Score=89, Evalue=2e-17, Organism=Homo sapiens, GI19913408, Length=244, Percent_Identity=28.2786885245902, Blast_Score=77, Evalue=9e-14, Organism=Escherichia coli, GI1788562, Length=508, Percent_Identity=26.9685039370079, Blast_Score=176, Evalue=7e-45, Organism=Escherichia coli, GI1789396, Length=338, Percent_Identity=34.6153846153846, Blast_Score=162, Evalue=7e-41, Organism=Caenorhabditis elegans, GI17535065, Length=273, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=4e-14, Organism=Caenorhabditis elegans, GI212645845, Length=390, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=272, Percent_Identity=28.6764705882353, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI17136538, Length=273, Percent_Identity=27.8388278388278, Blast_Score=87, Evalue=4e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013760 [H]
Pfam domain/function: PF00521 DNA_topoisoIV [H]
EC number: 5.99.1.-
Molecular weight: Translated: 104315; Mature: 104315
Theoretical pI: Translated: 5.00; Mature: 5.00
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRPEDKEDDYIEDKENEEIEDINSDTQDNEATEEEANTHSDYKVPGKGDTRVTTYHLSGM CCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHCCCCCCEECCCCCCCEEEEEEECCH YQNWFLDYASYVILERAVPHINDGLKPVQRRILHSMRRLDDGRYNKVANIVGHTMQFHPH HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCC GDASIGDALVQLGQKDLLIDCQGNWGNILTGDGAAAPRYIEARLSKFALETVFNPKTTLW CCCHHHHHHHHCCCCEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEE QLSYDGRNKEPVTLPVKFPLLLAQGVEGIAVGLSSKILPHNFNELLDASIAYLRGEEFAL EEEECCCCCCCEEEEEEHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEE YPDFQTGGSIDIAKYNDGERGGSVKVRAKIGKLDNKTLVISEIPYGKTTSTVIESILKAN ECCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCC DKGKIKIKKVDDNTAKDVEILVHLAPGVSSDKTIDALYAFTDCEISISPNCCVIKEDKPH CCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEEECCCEEEEECCCCC FLTVSDVLHHSTDRTLELLREELKIQKQEQEEALFFASLEKIFIEERIYKDPEFENAKNM EEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH DEAISHIDLRLEPFKPRFIREVTRDDILKLMEIKMGRILKFNSDKSNEFIAQTLEQIAKI HHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHH NDKLEHIIDYTIDWFTMLKEKYGKAYPRHTVIRNFDTIEATKVVEANEKLYINRQEGFIG HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEECCCEEEEEECCCEEE MGLKKDEFICNCSDIDDVIIFYRNGTYKIVKVADKIFIGKDILYVNVFKRNDNRTIYNVI CCCCCCCEEECCCCCCEEEEEEECCCEEEEEEECHHEECCEEEEEEEEEECCCCEEEEEE YRDGKFGYNYIKRFAVTGATRDREYDLTKGTENSRVLYFSANPNGEAETVKVILKPKPRQ EECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCC KLLVFEKNFSEIAIKGRGSQGNILTKAEVHKISLKQKGSSTLGGREVWFDWDVLRLNYDG EEEEEECCCCEEEEEECCCCCCEEEEEHEEEEEECCCCCCCCCCCEEEEEEEEEEEECCC RGEELGEFHSNDQILVILPNGDFYVTNFDLSNHYESNIMVIEKYQPSKIWTAVLYDADQK CCCHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEEEEECCCC YYYIKRFLLEVNTRKQNFLGENPKNRLMLLTDEVYPRIEVIFGGHDAFREALVLDADEFI HHHHHHHHHHHCCCHHHCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHEECCCCEE AVKGFKAKGKRISTFEVETINELEPNRFVPSENASESDDTEGNEEENDTDDGQSTTDIID EEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH EITGQMKLFDE HHCCCEEECCC >Mature Secondary Structure MRPEDKEDDYIEDKENEEIEDINSDTQDNEATEEEANTHSDYKVPGKGDTRVTTYHLSGM CCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHCCCCCCEECCCCCCCEEEEEEECCH YQNWFLDYASYVILERAVPHINDGLKPVQRRILHSMRRLDDGRYNKVANIVGHTMQFHPH HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCC GDASIGDALVQLGQKDLLIDCQGNWGNILTGDGAAAPRYIEARLSKFALETVFNPKTTLW CCCHHHHHHHHCCCCEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEE QLSYDGRNKEPVTLPVKFPLLLAQGVEGIAVGLSSKILPHNFNELLDASIAYLRGEEFAL EEEECCCCCCCEEEEEEHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEE YPDFQTGGSIDIAKYNDGERGGSVKVRAKIGKLDNKTLVISEIPYGKTTSTVIESILKAN ECCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCC DKGKIKIKKVDDNTAKDVEILVHLAPGVSSDKTIDALYAFTDCEISISPNCCVIKEDKPH CCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEEECCCEEEEECCCCC FLTVSDVLHHSTDRTLELLREELKIQKQEQEEALFFASLEKIFIEERIYKDPEFENAKNM EEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH DEAISHIDLRLEPFKPRFIREVTRDDILKLMEIKMGRILKFNSDKSNEFIAQTLEQIAKI HHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHH NDKLEHIIDYTIDWFTMLKEKYGKAYPRHTVIRNFDTIEATKVVEANEKLYINRQEGFIG HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEECCCEEEEEECCCEEE MGLKKDEFICNCSDIDDVIIFYRNGTYKIVKVADKIFIGKDILYVNVFKRNDNRTIYNVI CCCCCCCEEECCCCCCEEEEEEECCCEEEEEEECHHEECCEEEEEEEEEECCCCEEEEEE YRDGKFGYNYIKRFAVTGATRDREYDLTKGTENSRVLYFSANPNGEAETVKVILKPKPRQ EECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCC KLLVFEKNFSEIAIKGRGSQGNILTKAEVHKISLKQKGSSTLGGREVWFDWDVLRLNYDG EEEEEECCCCEEEEEECCCCCCEEEEEHEEEEEECCCCCCCCCCCEEEEEEEEEEEECCC RGEELGEFHSNDQILVILPNGDFYVTNFDLSNHYESNIMVIEKYQPSKIWTAVLYDADQK CCCHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEEEEECCCC YYYIKRFLLEVNTRKQNFLGENPKNRLMLLTDEVYPRIEVIFGGHDAFREALVLDADEFI HHHHHHHHHHHCCCHHHCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHEECCCCEE AVKGFKAKGKRISTFEVETINELEPNRFVPSENASESDDTEGNEEENDTDDGQSTTDIID EEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH EITGQMKLFDE HHCCCEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9403685 [H]