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The map label for this gene is ade

Identifier: 150009553

GI number: 150009553

Start: 3549704

End: 3551341

Strand: Direct

Name: ade

Synonym: BDI_2966

Alternate gene names: 150009553

Gene position: 3549704-3551341 (Clockwise)

Preceding gene: 150009552

Following gene: 150009554

Centisome position: 73.78

GC content: 45.54

Gene sequence:

>1638_bases
ATGAATGAAGCTAAAACACTGGTTATACGAGGAAATCTGGTAGATATAATCAACAGGCGCACCTTCGGGGCAGAGATTTC
AATCCTAAACGGGCATATCGGAAAGGTAATCCCTACCGGACAAGATGAGGGATCTTACCTCCTCCCCGGCTTTATTGACG
CGCATGTCCATATAGAGAGTAGCATGGTAACCCCTGCGGCATTCATTCACGCAGCCGTACGCCATGGCAGTATCGGTGCC
GTGGCGGACCCTCATGAGATAGCGAATGTAATGGGTACCGAAGGAGTCGAATATATGCTCGACAACGCGAAAGGGATTCC
TTTCTACACATGGTTCGGTGTCCCATCTTGCGTACCGGCTACGATTATGGAAACCTCCGGTGCGATCATAGACGCAGACG
AAACCGCTCGTTTGTTGGAACGAGAGGATCTACACTTCTTGGCAGAGATGATGAATTACCCCGGAGTCTTAAATAAAGAT
CCGGAAGTTATGCGCAAAATAGAAGCCGCGAAAAACGCAGGGAAACCCATCGACGGACATTATCCCCTAGCAACAGGCCC
CAAGCTAAAGGCATATATCGAGTCTGGCATTTCCACCGATCATGAAACCATCTATCTAGAAAAAGGCCGTGAAAAATGTG
AGCTTGGGATGCATGTCCTTATTCGGGAAGGAAGCGCGGCGAAAAACTTTGACGCACTTCATCCGCTATTGAAAGAGTAT
CCCGAACAAATCATGTTCTGTACGGATGACGCGCATCCTTCGTTTTTAAACAAAGGACACATAAATAGGATGGTAAAAAA
ATCGCTGGATTTAGGATATGATCTATATGATGTATTACGGGCCGCTTCCTATAATCCGGCCATGCACTACAAAATTCCCG
CAGGTTTCTTACGAGAGGGAGACTCCGCCGATTTTATCCAAGTAAACAATTTAAAGAATCTAACCATACAGGCAACCTAT
ATACAAGGAACCTGTGTATACGATGGAGAGAAATGCACGCTTCCTTTCCACAAACCTATACTCCGCAATAATTTCCACAC
GAAACCGATCCCATTAGAAAAGCTAGCGGTAAAAGCGAAAGGAAAACAGATGCGTGTCATTGTTTGCGAAGACCGCGAAT
TAATCACGAAAGAAGAACTATATCCTGTACATACATTCGATGGATTTGTAGAATCAGATACAGAACGAGACATTTTAAAA
CTCGTCATTCTAAATCGCTATCAAACGGCTCCTCCGGCTATTGCCTTTATAAAAGGAACAGGGCTCAAGCTCGGTGCCAT
CGCTCAAAGTATCTCCCACGATAGCCATAACATCATCGCTATAGGCGTAACCGATTTCGAGCTTATGCAAGCGATCAATG
TGGTCATAAAAGCGAAAGGAGGAATCGCCGTGAGCTGCATGGACGAAGTCACTCTCCTGCCCTTGCCGGTAGCGGGATTG
ATGAGCGACGAATCATTGGAAGAGACGAGCCGCCGTTACGAAGAGATCGAGGAAAAGATCAAGCGATTAAAATCCCCGAT
GGATTCATTACAAATGACGCTTTCTTTTATGGGATTGTTGGCGATCCCATCCTTAAAACTTAGCAACAAAGGTTTGTTCA
ATAGCGAGACATTCCAATTTACTTCCCTATTCGTATGA

Upstream 100 bases:

>100_bases
TCCCGGGTATTTCCCCTAGCGACATCAACATCCTTTTGGTACTGCTCGGAAGATAAAACACGAAATGTTCCACGTGAAAC
ATATTAAAGAAGATATTCAA

Downstream 100 bases:

>100_bases
TAGCCGATAAAGACGAACATATCAAGACGATCCTATCGGTCATTCCGGAAAAGCCGGGATGCTACCAGTATTTCGATGAA
AACGGAACGATTATATACGT

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MNEAKTLVIRGNLVDIINRRTFGAEISILNGHIGKVIPTGQDEGSYLLPGFIDAHVHIESSMVTPAAFIHAAVRHGSIGA
VADPHEIANVMGTEGVEYMLDNAKGIPFYTWFGVPSCVPATIMETSGAIIDADETARLLEREDLHFLAEMMNYPGVLNKD
PEVMRKIEAAKNAGKPIDGHYPLATGPKLKAYIESGISTDHETIYLEKGREKCELGMHVLIREGSAAKNFDALHPLLKEY
PEQIMFCTDDAHPSFLNKGHINRMVKKSLDLGYDLYDVLRAASYNPAMHYKIPAGFLREGDSADFIQVNNLKNLTIQATY
IQGTCVYDGEKCTLPFHKPILRNNFHTKPIPLEKLAVKAKGKQMRVIVCEDRELITKEELYPVHTFDGFVESDTERDILK
LVILNRYQTAPPAIAFIKGTGLKLGAIAQSISHDSHNIIAIGVTDFELMQAINVVIKAKGGIAVSCMDEVTLLPLPVAGL
MSDESLEETSRRYEEIEEKIKRLKSPMDSLQMTLSFMGLLAIPSLKLSNKGLFNSETFQFTSLFV

Sequences:

>Translated_545_residues
MNEAKTLVIRGNLVDIINRRTFGAEISILNGHIGKVIPTGQDEGSYLLPGFIDAHVHIESSMVTPAAFIHAAVRHGSIGA
VADPHEIANVMGTEGVEYMLDNAKGIPFYTWFGVPSCVPATIMETSGAIIDADETARLLEREDLHFLAEMMNYPGVLNKD
PEVMRKIEAAKNAGKPIDGHYPLATGPKLKAYIESGISTDHETIYLEKGREKCELGMHVLIREGSAAKNFDALHPLLKEY
PEQIMFCTDDAHPSFLNKGHINRMVKKSLDLGYDLYDVLRAASYNPAMHYKIPAGFLREGDSADFIQVNNLKNLTIQATY
IQGTCVYDGEKCTLPFHKPILRNNFHTKPIPLEKLAVKAKGKQMRVIVCEDRELITKEELYPVHTFDGFVESDTERDILK
LVILNRYQTAPPAIAFIKGTGLKLGAIAQSISHDSHNIIAIGVTDFELMQAINVVIKAKGGIAVSCMDEVTLLPLPVAGL
MSDESLEETSRRYEEIEEKIKRLKSPMDSLQMTLSFMGLLAIPSLKLSNKGLFNSETFQFTSLFV
>Mature_545_residues
MNEAKTLVIRGNLVDIINRRTFGAEISILNGHIGKVIPTGQDEGSYLLPGFIDAHVHIESSMVTPAAFIHAAVRHGSIGA
VADPHEIANVMGTEGVEYMLDNAKGIPFYTWFGVPSCVPATIMETSGAIIDADETARLLEREDLHFLAEMMNYPGVLNKD
PEVMRKIEAAKNAGKPIDGHYPLATGPKLKAYIESGISTDHETIYLEKGREKCELGMHVLIREGSAAKNFDALHPLLKEY
PEQIMFCTDDAHPSFLNKGHINRMVKKSLDLGYDLYDVLRAASYNPAMHYKIPAGFLREGDSADFIQVNNLKNLTIQATY
IQGTCVYDGEKCTLPFHKPILRNNFHTKPIPLEKLAVKAKGKQMRVIVCEDRELITKEELYPVHTFDGFVESDTERDILK
LVILNRYQTAPPAIAFIKGTGLKLGAIAQSISHDSHNIIAIGVTDFELMQAINVVIKAKGGIAVSCMDEVTLLPLPVAGL
MSDESLEETSRRYEEIEEKIKRLKSPMDSLQMTLSFMGLLAIPSLKLSNKGLFNSETFQFTSLFV

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=515, Percent_Identity=35.3398058252427, Blast_Score=294, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_PARD8 (A6LG60)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001304296.1
- ProteinModelPortal:   A6LG60
- STRING:   A6LG60
- GeneID:   5308115
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2966
- eggNOG:   COG1001
- HOGENOM:   HBG725357
- OMA:   VGLGEMM
- BioCyc:   PDIS435591:BDI_2966-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 60358; Mature: 60358

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAKTLVIRGNLVDIINRRTFGAEISILNGHIGKVIPTGQDEGSYLLPGFIDAHVHIES
CCCCCEEEEECCHHHHHCCCCCCCEEEEECCCCCCEECCCCCCCCEECCCEEEEEEEEEC
SMVTPAAFIHAAVRHGSIGAVADPHEIANVMGTEGVEYMLDNAKGIPFYTWFGVPSCVPA
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCEEEECCCCCCCCH
TIMETSGAIIDADETARLLEREDLHFLAEMMNYPGVLNKDPEVMRKIEAAKNAGKPIDGH
HHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
YPLATGPKLKAYIESGISTDHETIYLEKGREKCELGMHVLIREGSAAKNFDALHPLLKEY
CCCCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHC
PEQIMFCTDDAHPSFLNKGHINRMVKKSLDLGYDLYDVLRAASYNPAMHYKIPAGFLREG
CHHEEEEECCCCCCHHCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCHHHHCCC
DSADFIQVNNLKNLTIQATYIQGTCVYDGEKCTLPFHKPILRNNFHTKPIPLEKLAVKAK
CCCCEEEECCCCCEEEEEEEEEEEEEECCCEEECCCCCHHHHCCCCCCCCCHHHHHEEEC
GKQMRVIVCEDRELITKEELYPVHTFDGFVESDTERDILKLVILNRYQTAPPAIAFIKGT
CCEEEEEEECCCCCCCHHHCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECC
GLKLGAIAQSISHDSHNIIAIGVTDFELMQAINVVIKAKGGIAVSCMDEVTLLPLPVAGL
CCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHEEEEECCCEEEEEECCCEEECCCCHHH
MSDESLEETSRRYEEIEEKIKRLKSPMDSLQMTLSFMGLLAIPSLKLSNKGLFNSETFQF
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEE
TSLFV
EEECC
>Mature Secondary Structure
MNEAKTLVIRGNLVDIINRRTFGAEISILNGHIGKVIPTGQDEGSYLLPGFIDAHVHIES
CCCCCEEEEECCHHHHHCCCCCCCEEEEECCCCCCEECCCCCCCCEECCCEEEEEEEEEC
SMVTPAAFIHAAVRHGSIGAVADPHEIANVMGTEGVEYMLDNAKGIPFYTWFGVPSCVPA
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCEEEECCCCCCCCH
TIMETSGAIIDADETARLLEREDLHFLAEMMNYPGVLNKDPEVMRKIEAAKNAGKPIDGH
HHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
YPLATGPKLKAYIESGISTDHETIYLEKGREKCELGMHVLIREGSAAKNFDALHPLLKEY
CCCCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHC
PEQIMFCTDDAHPSFLNKGHINRMVKKSLDLGYDLYDVLRAASYNPAMHYKIPAGFLREG
CHHEEEEECCCCCCHHCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCHHHHCCC
DSADFIQVNNLKNLTIQATYIQGTCVYDGEKCTLPFHKPILRNNFHTKPIPLEKLAVKAK
CCCCEEEECCCCCEEEEEEEEEEEEEECCCEEECCCCCHHHHCCCCCCCCCHHHHHEEEC
GKQMRVIVCEDRELITKEELYPVHTFDGFVESDTERDILKLVILNRYQTAPPAIAFIKGT
CCEEEEEEECCCCCCCHHHCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECC
GLKLGAIAQSISHDSHNIIAIGVTDFELMQAINVVIKAKGGIAVSCMDEVTLLPLPVAGL
CCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHEEEEECCCEEEEEECCCEEECCCCHHH
MSDESLEETSRRYEEIEEKIKRLKSPMDSLQMTLSFMGLLAIPSLKLSNKGLFNSETFQF
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEE
TSLFV
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA