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The map label for this gene is typA [H]

Identifier: 150009361

GI number: 150009361

Start: 3302881

End: 3304677

Strand: Reverse

Name: typA [H]

Synonym: BDI_2769

Alternate gene names: 150009361

Gene position: 3304677-3302881 (Counterclockwise)

Preceding gene: 150009369

Following gene: 150009357

Centisome position: 68.68

GC content: 48.19

Gene sequence:

>1797_bases
ATGCAAAAGATCAGAAACATTGCGATTATCGCGCACGTAGACCACGGCAAAACGACGCTCGTGGATAAGATGTTATTAGC
CGGTAAGCTTTTCCGTGAAGGACAGGCAGAACCGGATCAGTTCATGGATAACAATGATCTGGAACGGGAACGAGGTATCA
CGATTCTTGCCAAGAACGTGTCTATCAATTATAAGGGATATAAGATCAATATTATTGACACTCCGGGCCACGCCGACTTT
GGTGGCGAGGTGGAGCGTGTCTTGAATATGGCGGATGGTTGTTTGCTATTGGTAGACGCCTTTGAGGGGCCTATGCCGCA
GACTCGTTTTGTTTTGCAAAAAGCGATTCAACTGGGTTTGAAGCCGATCGTGGTAATTAATAAGGTGGATAAGCCGAATT
GCCGCCCGTCGGAAGTGCAGGAAATGGTATTCGACTTGATGTTTAGTCTGGATGCTACCGAGGAGCAGCTTGACTTCCCT
ACTATTTATGGTTCCGCCAAGCAGGGCTGGATGTCCGAGGATTGGAAGGAGCCGAAAGAGGATATCGCGGCTGTGCTTGA
TGCGATCATCAAGTATATCCCCGAACCAAAGATGTTGGAGGGTACTCCGCAGATGTTGATTACTTCTTTGGATTATTCTA
AGTATGTAGGTCGTATCGCCGTAGGACGTGTACACCGTGGCGAGTTGAAAGAGGGCCAAGATGTCATGCTTTGTAAGCGT
GATGGTAGTATGGTGAAATCGAGGATCAAGGAAGTGGATGTATTCGAGGGCTTGGGACGTACGAAAGTTGATTCCGTGCA
GTCCGGGGATATTTGCGCTATTATCGGTATCGATGGTTTCGAGATCGGTGAGACTATCGCCGACGTGAACGAGCCGGAGC
CATTGCCAACGATCGCTATCGACGAGCCTACGATGTCTATGCTTTTCACGATCAACAATTCTCCGTTCTTTGGTAAGGAT
GGTAAGTTTGTTACTTCCCGTCATATTTTTGACCGTTTGCAGAAAGAATTGGATAAGAACTTGGCTTTACGCGTAGTTCC
TACTGATTCCGCTGATTCTTGGTTGGTATATGGCCGTGGCGTGCTTCACTTGTCTGTATTGATCGAGACGATGCGTCGTG
AGGGATACGAGTTGCAGGTAGGTCAGCCTCAGGTTATCATCAAGGAGATCGATGGTGAGAAATGTGAGCCGGTAGAGCAA
TTGACGGTGAATCTTCCGGAGGAATGCTCTAGCCGTATTATCGATATGGTAACGAAACGTAAGGGCGAGATGACCATGAT
GGAAAGCAAGAATGGTCGTATGCACTTGGAGTTCACGATTCCTTCCCGTGGTATTATCGGTTTGAACAACGCTGTATTGA
CCGCCTCTGCCGGTGAGGCTATCATGGCACACCGTTTCTTGGAATATCAACCGTGGAAGGGTGATATCGAACGACGTATG
AATGGTTCGATTATCGCTATGGAGACAGGTCAGGCTTTCGCTTATGCCCTGAATAACTTGCAATCCCGCGGACGTTTCTT
CATCGCCCCGGGCGAGGAGGTTTACGCTGGACAGGTGGTTGGTGAGCATACCAAGGACAATGACTTGGTGGTAAATGTTA
CCAAATCCAAGAAGTTGACGAATATGCGTGCCTCTGGTTCGGACGACAAAGTTTCCTTGGCTCCTCCTATCGTATTCAGC
CTAGAGGATGCGCTTGAGTACATCAAGGGCGATGAGTACGTAGAGATCACCCCGAATAATATGCGTATGCGTAAGATCAT
CTTGGATGAGACAGAGCGTAAGCGCCAAGGTAGATAA

Upstream 100 bases:

>100_bases
TTTGCAATAGATTCTGCTATCTTTTTTGTGTTTTGAAGCATGAATGTCATATATATATCGTAAAAATATCGTATTTTTGC
AGCCAATAAATTAGTCTTCA

Downstream 100 bases:

>100_bases
TATATTCTTCTATTAATAGATACAAAAAACGGCGGGCCTTTAAAAAGCCCGCCGTTTTTTATATGATGTTAGGATTTTAG
AGATCCTTCAATGAGTGTGT

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MQKIRNIAIIAHVDHGKTTLVDKMLLAGKLFREGQAEPDQFMDNNDLERERGITILAKNVSINYKGYKINIIDTPGHADF
GGEVERVLNMADGCLLLVDAFEGPMPQTRFVLQKAIQLGLKPIVVINKVDKPNCRPSEVQEMVFDLMFSLDATEEQLDFP
TIYGSAKQGWMSEDWKEPKEDIAAVLDAIIKYIPEPKMLEGTPQMLITSLDYSKYVGRIAVGRVHRGELKEGQDVMLCKR
DGSMVKSRIKEVDVFEGLGRTKVDSVQSGDICAIIGIDGFEIGETIADVNEPEPLPTIAIDEPTMSMLFTINNSPFFGKD
GKFVTSRHIFDRLQKELDKNLALRVVPTDSADSWLVYGRGVLHLSVLIETMRREGYELQVGQPQVIIKEIDGEKCEPVEQ
LTVNLPEECSSRIIDMVTKRKGEMTMMESKNGRMHLEFTIPSRGIIGLNNAVLTASAGEAIMAHRFLEYQPWKGDIERRM
NGSIIAMETGQAFAYALNNLQSRGRFFIAPGEEVYAGQVVGEHTKDNDLVVNVTKSKKLTNMRASGSDDKVSLAPPIVFS
LEDALEYIKGDEYVEITPNNMRMRKIILDETERKRQGR

Sequences:

>Translated_598_residues
MQKIRNIAIIAHVDHGKTTLVDKMLLAGKLFREGQAEPDQFMDNNDLERERGITILAKNVSINYKGYKINIIDTPGHADF
GGEVERVLNMADGCLLLVDAFEGPMPQTRFVLQKAIQLGLKPIVVINKVDKPNCRPSEVQEMVFDLMFSLDATEEQLDFP
TIYGSAKQGWMSEDWKEPKEDIAAVLDAIIKYIPEPKMLEGTPQMLITSLDYSKYVGRIAVGRVHRGELKEGQDVMLCKR
DGSMVKSRIKEVDVFEGLGRTKVDSVQSGDICAIIGIDGFEIGETIADVNEPEPLPTIAIDEPTMSMLFTINNSPFFGKD
GKFVTSRHIFDRLQKELDKNLALRVVPTDSADSWLVYGRGVLHLSVLIETMRREGYELQVGQPQVIIKEIDGEKCEPVEQ
LTVNLPEECSSRIIDMVTKRKGEMTMMESKNGRMHLEFTIPSRGIIGLNNAVLTASAGEAIMAHRFLEYQPWKGDIERRM
NGSIIAMETGQAFAYALNNLQSRGRFFIAPGEEVYAGQVVGEHTKDNDLVVNVTKSKKLTNMRASGSDDKVSLAPPIVFS
LEDALEYIKGDEYVEITPNNMRMRKIILDETERKRQGR
>Mature_598_residues
MQKIRNIAIIAHVDHGKTTLVDKMLLAGKLFREGQAEPDQFMDNNDLERERGITILAKNVSINYKGYKINIIDTPGHADF
GGEVERVLNMADGCLLLVDAFEGPMPQTRFVLQKAIQLGLKPIVVINKVDKPNCRPSEVQEMVFDLMFSLDATEEQLDFP
TIYGSAKQGWMSEDWKEPKEDIAAVLDAIIKYIPEPKMLEGTPQMLITSLDYSKYVGRIAVGRVHRGELKEGQDVMLCKR
DGSMVKSRIKEVDVFEGLGRTKVDSVQSGDICAIIGIDGFEIGETIADVNEPEPLPTIAIDEPTMSMLFTINNSPFFGKD
GKFVTSRHIFDRLQKELDKNLALRVVPTDSADSWLVYGRGVLHLSVLIETMRREGYELQVGQPQVIIKEIDGEKCEPVEQ
LTVNLPEECSSRIIDMVTKRKGEMTMMESKNGRMHLEFTIPSRGIIGLNNAVLTASAGEAIMAHRFLEYQPWKGDIERRM
NGSIIAMETGQAFAYALNNLQSRGRFFIAPGEEVYAGQVVGEHTKDNDLVVNVTKSKKLTNMRASGSDDKVSLAPPIVFS
LEDALEYIKGDEYVEITPNNMRMRKIILDETERKRQGR

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=524, Percent_Identity=27.4809160305344, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI94966754, Length=132, Percent_Identity=43.1818181818182, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4503483, Length=144, Percent_Identity=38.1944444444444, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI34147630, Length=279, Percent_Identity=32.258064516129, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI25306287, Length=136, Percent_Identity=41.9117647058824, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19923640, Length=136, Percent_Identity=41.9117647058824, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI25306283, Length=136, Percent_Identity=41.9117647058824, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=40.1360544217687, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=41.8181818181818, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=41.8181818181818, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=41.8181818181818, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI217272894, Length=136, Percent_Identity=37.5, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI217272892, Length=136, Percent_Identity=37.5, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI94966752, Length=81, Percent_Identity=45.679012345679, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI48994988, Length=601, Percent_Identity=50.7487520798669, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1788922, Length=552, Percent_Identity=28.9855072463768, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI1790412, Length=239, Percent_Identity=32.6359832635983, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789737, Length=239, Percent_Identity=32.6359832635983, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789738, Length=140, Percent_Identity=36.4285714285714, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790835, Length=148, Percent_Identity=34.4594594594595, Blast_Score=79, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17557151, Length=397, Percent_Identity=29.9748110831234, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17556745, Length=157, Percent_Identity=39.4904458598726, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=40, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=40, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17506493, Length=158, Percent_Identity=34.8101265822785, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17533571, Length=141, Percent_Identity=39.7163120567376, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17556456, Length=285, Percent_Identity=34.3859649122807, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=135, Percent_Identity=37.7777777777778, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25141371, Length=285, Percent_Identity=30.5263157894737, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994658, Length=229, Percent_Identity=29.6943231441048, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=485, Percent_Identity=29.2783505154639, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6324707, Length=144, Percent_Identity=39.5833333333333, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320593, Length=144, Percent_Identity=39.5833333333333, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324761, Length=284, Percent_Identity=32.0422535211268, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323098, Length=143, Percent_Identity=39.1608391608392, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322359, Length=135, Percent_Identity=40.7407407407407, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=35.5555555555556, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324550, Length=250, Percent_Identity=29.2, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI78706572, Length=517, Percent_Identity=27.2727272727273, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28574573, Length=139, Percent_Identity=41.0071942446043, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24585709, Length=150, Percent_Identity=37.3333333333333, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585711, Length=150, Percent_Identity=37.3333333333333, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585713, Length=150, Percent_Identity=37.3333333333333, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24582462, Length=144, Percent_Identity=39.5833333333333, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281363316, Length=276, Percent_Identity=31.5217391304348, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17864358, Length=276, Percent_Identity=31.5217391304348, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221458488, Length=160, Percent_Identity=38.125, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19921738, Length=271, Percent_Identity=30.6273062730627, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=37.3134328358209, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28572034, Length=130, Percent_Identity=36.9230769230769, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 67065; Mature: 67065

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIRNIAIIAHVDHGKTTLVDKMLLAGKLFREGQAEPDQFMDNNDLERERGITILAKNV
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHCCCEEEEEEE
SINYKGYKINIIDTPGHADFGGEVERVLNMADGCLLLVDAFEGPMPQTRFVLQKAIQLGL
EEEECCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
KPIVVINKVDKPNCRPSEVQEMVFDLMFSLDATEEQLDFPTIYGSAKQGWMSEDWKEPKE
CEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCEEECCCCCCCCCCHHCCHHH
DIAAVLDAIIKYIPEPKMLEGTPQMLITSLDYSKYVGRIAVGRVHRGELKEGQDVMLCKR
HHHHHHHHHHHHCCCCCCCCCCHHHEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEECC
DGSMVKSRIKEVDVFEGLGRTKVDSVQSGDICAIIGIDGFEIGETIADVNEPEPLPTIAI
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCEEEE
DEPTMSMLFTINNSPFFGKDGKFVTSRHIFDRLQKELDKNLALRVVPTDSADSWLVYGRG
CCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCH
VLHLSVLIETMRREGYELQVGQPQVIIKEIDGEKCEPVEQLTVNLPEECSSRIIDMVTKR
HHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHCC
KGEMTMMESKNGRMHLEFTIPSRGIIGLNNAVLTASAGEAIMAHRFLEYQPWKGDIERRM
CCCEEEEECCCCEEEEEEECCCCCEEECCCEEEEECCCCHHHHHHHHCCCCCCCHHHHCC
NGSIIAMETGQAFAYALNNLQSRGRFFIAPGEEVYAGQVVGEHTKDNDLVVNVTKSKKLT
CCCEEEEECCCHHHHHHHHHHHCCEEEECCCCCEEECCEECCCCCCCCEEEEEECCCCHH
NMRASGSDDKVSLAPPIVFSLEDALEYIKGDEYVEITPNNMRMRKIILDETERKRQGR
CCCCCCCCCCEEECCCEEEEHHHHHHHHCCCCEEEECCCCCEEEEEHHCCHHHHHCCC
>Mature Secondary Structure
MQKIRNIAIIAHVDHGKTTLVDKMLLAGKLFREGQAEPDQFMDNNDLERERGITILAKNV
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHCCCEEEEEEE
SINYKGYKINIIDTPGHADFGGEVERVLNMADGCLLLVDAFEGPMPQTRFVLQKAIQLGL
EEEECCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
KPIVVINKVDKPNCRPSEVQEMVFDLMFSLDATEEQLDFPTIYGSAKQGWMSEDWKEPKE
CEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCEEECCCCCCCCCCHHCCHHH
DIAAVLDAIIKYIPEPKMLEGTPQMLITSLDYSKYVGRIAVGRVHRGELKEGQDVMLCKR
HHHHHHHHHHHHCCCCCCCCCCHHHEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEECC
DGSMVKSRIKEVDVFEGLGRTKVDSVQSGDICAIIGIDGFEIGETIADVNEPEPLPTIAI
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCEEEE
DEPTMSMLFTINNSPFFGKDGKFVTSRHIFDRLQKELDKNLALRVVPTDSADSWLVYGRG
CCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCH
VLHLSVLIETMRREGYELQVGQPQVIIKEIDGEKCEPVEQLTVNLPEECSSRIIDMVTKR
HHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHCC
KGEMTMMESKNGRMHLEFTIPSRGIIGLNNAVLTASAGEAIMAHRFLEYQPWKGDIERRM
CCCEEEEECCCCEEEEEEECCCCCEEECCCEEEEECCCCHHHHHHHHCCCCCCCHHHHCC
NGSIIAMETGQAFAYALNNLQSRGRFFIAPGEEVYAGQVVGEHTKDNDLVVNVTKSKKLT
CCCEEEEECCCHHHHHHHHHHHCCEEEECCCCCEEECCEECCCCCCCCEEEEEECCCCHH
NMRASGSDDKVSLAPPIVFSLEDALEYIKGDEYVEITPNNMRMRKIILDETERKRQGR
CCCCCCCCCCEEECCCEEEEHHHHHHHHCCCCEEEECCCCCEEEEEHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]