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The map label for this gene is xseA [H]

Identifier: 150009300

GI number: 150009300

Start: 3209236

End: 3210570

Strand: Reverse

Name: xseA [H]

Synonym: BDI_2702

Alternate gene names: 150009300

Gene position: 3210570-3209236 (Counterclockwise)

Preceding gene: 150009301

Following gene: 150009299

Centisome position: 66.73

GC content: 48.31

Gene sequence:

>1335_bases
ATGCGGCCGAATCTAAATAACTTATCGGGTGAGAAAGAGGCTCTATCTTTGTTAGAGCTGAATACCCGCATACGGGGTGC
GTTGTCGAGGGCTTTCCCGGAGACTTGCTGGGTGCGTGCGGAGATGAGCGATGTGCGGGTGAATACTTCTTCCGGACATT
GTTATCTGGAGTTTGTGGAGAAGAATGCGCAGACCGGGCAATTGGTGGCCAAGGTACGAGGGTCTATCTGGGCGAAGACA
TTTCGTATGTTGAAACCTTATTTCGAGATGGAGACCGGTCAGATGTTCGCTTCCGGCTTGAAAGTGTTGGTGAAGGTGTC
TGTTGAGTTCCATGAGTTATATGGATTGAGCCTTACGGTGCTTGATATCGATCCGGCTTATACGTTGGGGGATATGGTGC
GTAAGCGTATGGAGATTATCCGCCAATTGCAGGAGGAAGGGGTCTTTACGCTGAATAAGGAATTGCCTTTTCCGCTACTT
CCTAGGAGAATCGCTATCATTACTTCTCCGACGGCTGCCGGCTACGAGGATTTTATGAATCAGTTGACACGGAATAAAGG
AGGTTATCCGTTCTATACCAAATTATTCCCCGCCTTGATGCAAGGAGAACGGACGGAGGCTTCTGTAATAGCGGCTTTAG
ACCGGATTTATCAACATCAAGATCTTTTTGATGTGGTCGTGATTATCCGTGGGGGTGGGGCTACCTCGGACTTGAATAGC
TTCGATTCTTATCTGTTGGCGGCGAATTGCGCTCAATTCCCTTTACCGATTATCACGGGTATCGGGCACGAACGGGATGA
TACGGTCGTAGATTTGGTGGCGCATACCCGGATGAAGACACCGACCGCTGTCGCTGAGTTCCTTATTTCTCGAATGGATA
GCGTAGGTGAGGAGTTGGAGAATTTGTGTCAAGACGTGAGTTTATTGGCTATGGATATTCTATCCCGCCAGAAAAACTAT
TTGCAATTGGTCGCTACCCGTTTCCCCTCTATCGTGACAAGCCGGATCGAGCGGAATCGTTCGGGACTGCAAACAATCGC
GAGTGGTTTACCTGCGATGGCATCGGGCTTGTTATCACGCCGCCAGTCGGTGCTTGAGAATACGGAACTTCGCTTGCGAA
ACGGTATTACCTCTAAACTCTCCGAGGATGTGCGTTTTATCCAGCTTACGGAACAGTTTATCAAGATGGCTTCTCCTGAT
TATATCTTAAAGCGAGGCTATAGCTTAGCCTTGAAAGATGGCAAGATTATCAAACATGCCTCTGATTTGCGAGCCGGCGA
AGAACTGACGACTCGCTTCATCGATGGTGAAATAAAAAGTATTATCAAACCATAG

Upstream 100 bases:

>100_bases
TCTCTTTTGCAGCGTTTCGGCAGTAAGTTTGAGCAACCGGACGCTGAGTTGGGATATGGCATCCCGGATGTGTACAAAGC
TTATAAACAGGAGCGTAAAT

Downstream 100 bases:

>100_bases
AGGGTGGTTTTATAACCGTCCGATAAATACATAATTAATATGGCGAAAAAAGAAGAAACATATAACGAGGCGATCGAGAA
ACTTCGTAAGATCGTGGCTG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MRPNLNNLSGEKEALSLLELNTRIRGALSRAFPETCWVRAEMSDVRVNTSSGHCYLEFVEKNAQTGQLVAKVRGSIWAKT
FRMLKPYFEMETGQMFASGLKVLVKVSVEFHELYGLSLTVLDIDPAYTLGDMVRKRMEIIRQLQEEGVFTLNKELPFPLL
PRRIAIITSPTAAGYEDFMNQLTRNKGGYPFYTKLFPALMQGERTEASVIAALDRIYQHQDLFDVVVIIRGGGATSDLNS
FDSYLLAANCAQFPLPIITGIGHERDDTVVDLVAHTRMKTPTAVAEFLISRMDSVGEELENLCQDVSLLAMDILSRQKNY
LQLVATRFPSIVTSRIERNRSGLQTIASGLPAMASGLLSRRQSVLENTELRLRNGITSKLSEDVRFIQLTEQFIKMASPD
YILKRGYSLALKDGKIIKHASDLRAGEELTTRFIDGEIKSIIKP

Sequences:

>Translated_444_residues
MRPNLNNLSGEKEALSLLELNTRIRGALSRAFPETCWVRAEMSDVRVNTSSGHCYLEFVEKNAQTGQLVAKVRGSIWAKT
FRMLKPYFEMETGQMFASGLKVLVKVSVEFHELYGLSLTVLDIDPAYTLGDMVRKRMEIIRQLQEEGVFTLNKELPFPLL
PRRIAIITSPTAAGYEDFMNQLTRNKGGYPFYTKLFPALMQGERTEASVIAALDRIYQHQDLFDVVVIIRGGGATSDLNS
FDSYLLAANCAQFPLPIITGIGHERDDTVVDLVAHTRMKTPTAVAEFLISRMDSVGEELENLCQDVSLLAMDILSRQKNY
LQLVATRFPSIVTSRIERNRSGLQTIASGLPAMASGLLSRRQSVLENTELRLRNGITSKLSEDVRFIQLTEQFIKMASPD
YILKRGYSLALKDGKIIKHASDLRAGEELTTRFIDGEIKSIIKP
>Mature_444_residues
MRPNLNNLSGEKEALSLLELNTRIRGALSRAFPETCWVRAEMSDVRVNTSSGHCYLEFVEKNAQTGQLVAKVRGSIWAKT
FRMLKPYFEMETGQMFASGLKVLVKVSVEFHELYGLSLTVLDIDPAYTLGDMVRKRMEIIRQLQEEGVFTLNKELPFPLL
PRRIAIITSPTAAGYEDFMNQLTRNKGGYPFYTKLFPALMQGERTEASVIAALDRIYQHQDLFDVVVIIRGGGATSDLNS
FDSYLLAANCAQFPLPIITGIGHERDDTVVDLVAHTRMKTPTAVAEFLISRMDSVGEELENLCQDVSLLAMDILSRQKNY
LQLVATRFPSIVTSRIERNRSGLQTIASGLPAMASGLLSRRQSVLENTELRLRNGITSKLSEDVRFIQLTEQFIKMASPD
YILKRGYSLALKDGKIIKHASDLRAGEELTTRFIDGEIKSIIKP

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=438, Percent_Identity=26.027397260274, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49809; Mature: 49809

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPNLNNLSGEKEALSLLELNTRIRGALSRAFPETCWVRAEMSDVRVNTSSGHCYLEFVE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEHHHEEEECCCCCEEEEEEC
KNAQTGQLVAKVRGSIWAKTFRMLKPYFEMETGQMFASGLKVLVKVSVEFHELYGLSLTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LDIDPAYTLGDMVRKRMEIIRQLQEEGVFTLNKELPFPLLPRRIAIITSPTAAGYEDFMN
EECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCCCCHHHHHH
QLTRNKGGYPFYTKLFPALMQGERTEASVIAALDRIYQHQDLFDVVVIIRGGGATSDLNS
HHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHH
FDSYLLAANCAQFPLPIITGIGHERDDTVVDLVAHTRMKTPTAVAEFLISRMDSVGEELE
HHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
NLCQDVSLLAMDILSRQKNYLQLVATRFPSIVTSRIERNRSGLQTIASGLPAMASGLLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RQSVLENTELRLRNGITSKLSEDVRFIQLTEQFIKMASPDYILKRGYSLALKDGKIIKHA
HHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCHHHHH
SDLRAGEELTTRFIDGEIKSIIKP
HHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRPNLNNLSGEKEALSLLELNTRIRGALSRAFPETCWVRAEMSDVRVNTSSGHCYLEFVE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEHHHEEEECCCCCEEEEEEC
KNAQTGQLVAKVRGSIWAKTFRMLKPYFEMETGQMFASGLKVLVKVSVEFHELYGLSLTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LDIDPAYTLGDMVRKRMEIIRQLQEEGVFTLNKELPFPLLPRRIAIITSPTAAGYEDFMN
EECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCCCCHHHHHH
QLTRNKGGYPFYTKLFPALMQGERTEASVIAALDRIYQHQDLFDVVVIIRGGGATSDLNS
HHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHH
FDSYLLAANCAQFPLPIITGIGHERDDTVVDLVAHTRMKTPTAVAEFLISRMDSVGEELE
HHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
NLCQDVSLLAMDILSRQKNYLQLVATRFPSIVTSRIERNRSGLQTIASGLPAMASGLLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RQSVLENTELRLRNGITSKLSEDVRFIQLTEQFIKMASPDYILKRGYSLALKDGKIIKHA
HHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCHHHHH
SDLRAGEELTTRFIDGEIKSIIKP
HHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]