Click here to switch to the map view.

The map label for this gene is rocD [H]

Identifier: 150009271

GI number: 150009271

Start: 3174292

End: 3175500

Strand: Reverse

Name: rocD [H]

Synonym: BDI_2673

Alternate gene names: 150009271

Gene position: 3175500-3174292 (Counterclockwise)

Preceding gene: 150009272

Following gene: 150009270

Centisome position: 66.0

GC content: 50.79

Gene sequence:

>1209_bases
ATGAAACCGGAAGATTACATCACCCGTGAGGAGAAGTATGGTGCCCACAACTATCATCCCCTGCCGGTCGTTCTCAGAAG
AGGCGAAGGCGTGTTCGTGTGGGACGTGGAAGGAAAACGTTATTTTGATTTCTTGTCCGGATATTCGGCGTTAAGCCAAG
GACATTGCCATCCTAAGATCGTAAAGGCCCTGATGGAGCAAGCGGAGAGGCTTACGCTCGTGTCTCGTGCCTTTCATGCT
GATATACTTGGTGAATACATGGAATTTACTTGCAAATTCTTCGGCTATGACAAACTTCTGCCGATGAATACGGGAGCCGA
GGCGGTAGAGACGGCCTTGAAGCTTTGCCGTCGGTGGGGATATCGTCGGAAAGGGGTTGCCCCGGAACGTGCGAAGATCG
TGGTTTGTAGCGAGAATTTCCATGGACGTACGATTACGATTATTTCCATGAGTACGGACCCTAGCTCATACGCCGATTTC
GGTCCTTATACACCCGGGTTTATAAAGATACCCTATAATAATGTGGATGCGTTGGCCGAGGCCCTGAAAGATCCTGATGC
AGTAGGCTTCTTGGTGGAACCGATCCAAGGTGAGGCTGGGGTAGTGGTGCCCGACGATGGTTATCTGCGGGCTTGCTATG
ATCTTTGTCATCAAAAGAATGTGTTGTTTATCGCGGACGAGATACAGACGGGTATCGGCCGTACCGGTAAGTTATTGGCT
TGCGATTACGAGGGGATTCGTCCGGACATCTTGATCTTGGGAAAGGCGTTGTCCGGTGGGGTCAGTCCGGTCTCGGCGGT
ATTGGCGGACGATGAGATCATGCTTACGATCGCTCCGGGAGAGCACGGTTCTACGTATGGTGGAAATCCGTTGGCGGCGA
AAGTCGCTATCGCAGCCTTGGAGGTGGTACGTGACGAGCATTTGTCGGAGAATGCGTTTAAGATGGGTGAGCTGTTCCGT
GGTGAGATGGAGCGGATTAATAATCCTATGATAAAGAAAGTACGGGGTAAGGGCTTGCTGAACGCTGTCGTGACGGAACC
TAAAGATGGGAAGACGGCATGGGACATCTGTTTGGCGTTGAAGGAAAACGGTTTGATAGCCAAGCCTACCCACGATCATA
TCATCCGCTTCACGCCTCCTTTGGTGATTACGGAGGAGCAAATGATGGAAGCGATTGGCATTATACGAGATACGTTTGCT
AAATTCTAG

Upstream 100 bases:

>100_bases
CATACGCTTTCGGTGACATATTGTAATCCCCTATTTCGTATCTTTGGCATATACGGTAAGAAACGCTTACAGTATGCTAA
TCATTTAAATCAGTAGCAGT

Downstream 100 bases:

>100_bases
TGTATGAAGATAAATGTAATAGGTGTTCCCTTGAATCTGGGATGTGACCGGGCTGGCGTAGAGCGTGCCCCGAACCACCT
TCGGGAACGGGGATTGATGG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MKPEDYITREEKYGAHNYHPLPVVLRRGEGVFVWDVEGKRYFDFLSGYSALSQGHCHPKIVKALMEQAERLTLVSRAFHA
DILGEYMEFTCKFFGYDKLLPMNTGAEAVETALKLCRRWGYRRKGVAPERAKIVVCSENFHGRTITIISMSTDPSSYADF
GPYTPGFIKIPYNNVDALAEALKDPDAVGFLVEPIQGEAGVVVPDDGYLRACYDLCHQKNVLFIADEIQTGIGRTGKLLA
CDYEGIRPDILILGKALSGGVSPVSAVLADDEIMLTIAPGEHGSTYGGNPLAAKVAIAALEVVRDEHLSENAFKMGELFR
GEMERINNPMIKKVRGKGLLNAVVTEPKDGKTAWDICLALKENGLIAKPTHDHIIRFTPPLVITEEQMMEAIGIIRDTFA
KF

Sequences:

>Translated_402_residues
MKPEDYITREEKYGAHNYHPLPVVLRRGEGVFVWDVEGKRYFDFLSGYSALSQGHCHPKIVKALMEQAERLTLVSRAFHA
DILGEYMEFTCKFFGYDKLLPMNTGAEAVETALKLCRRWGYRRKGVAPERAKIVVCSENFHGRTITIISMSTDPSSYADF
GPYTPGFIKIPYNNVDALAEALKDPDAVGFLVEPIQGEAGVVVPDDGYLRACYDLCHQKNVLFIADEIQTGIGRTGKLLA
CDYEGIRPDILILGKALSGGVSPVSAVLADDEIMLTIAPGEHGSTYGGNPLAAKVAIAALEVVRDEHLSENAFKMGELFR
GEMERINNPMIKKVRGKGLLNAVVTEPKDGKTAWDICLALKENGLIAKPTHDHIIRFTPPLVITEEQMMEAIGIIRDTFA
KF
>Mature_402_residues
MKPEDYITREEKYGAHNYHPLPVVLRRGEGVFVWDVEGKRYFDFLSGYSALSQGHCHPKIVKALMEQAERLTLVSRAFHA
DILGEYMEFTCKFFGYDKLLPMNTGAEAVETALKLCRRWGYRRKGVAPERAKIVVCSENFHGRTITIISMSTDPSSYADF
GPYTPGFIKIPYNNVDALAEALKDPDAVGFLVEPIQGEAGVVVPDDGYLRACYDLCHQKNVLFIADEIQTGIGRTGKLLA
CDYEGIRPDILILGKALSGGVSPVSAVLADDEIMLTIAPGEHGSTYGGNPLAAKVAIAALEVVRDEHLSENAFKMGELFR
GEMERINNPMIKKVRGKGLLNAVVTEPKDGKTAWDICLALKENGLIAKPTHDHIIRFTPPLVITEEQMMEAIGIIRDTFA
KF

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=399, Percent_Identity=61.6541353383459, Blast_Score=524, Evalue=1e-149,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=60.797342192691, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=27.0454545454545, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=26.2019230769231, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=26.9230769230769, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442709, Length=384, Percent_Identity=26.8229166666667, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=25.2403846153846, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI188536080, Length=432, Percent_Identity=23.6111111111111, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38679950, Length=432, Percent_Identity=23.6111111111111, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38679946, Length=432, Percent_Identity=23.6111111111111, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1789759, Length=386, Percent_Identity=34.7150259067358, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=34.9246231155779, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI145693181, Length=386, Percent_Identity=33.160621761658, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1789016, Length=411, Percent_Identity=29.9270072992701, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=30.5210918114144, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1786991, Length=423, Percent_Identity=28.3687943262411, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786349, Length=330, Percent_Identity=26.6666666666667, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=402, Percent_Identity=57.7114427860697, Blast_Score=496, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI25144274, Length=274, Percent_Identity=56.2043795620438, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI71981843, Length=175, Percent_Identity=58.8571428571429, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=28.8636363636364, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=422, Percent_Identity=26.7772511848341, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=414, Percent_Identity=25.1207729468599, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=412, Percent_Identity=52.9126213592233, Blast_Score=435, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6324432, Length=414, Percent_Identity=31.1594202898551, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6324386, Length=360, Percent_Identity=25.8333333333333, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321456, Length=411, Percent_Identity=23.3576642335766, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357415, Length=398, Percent_Identity=64.070351758794, Blast_Score=541, Evalue=1e-154,
Organism=Drosophila melanogaster, GI28574759, Length=415, Percent_Identity=26.9879518072289, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI161085790, Length=430, Percent_Identity=26.2790697674419, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356575, Length=420, Percent_Identity=26.6666666666667, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 44483; Mature: 44483

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPEDYITREEKYGAHNYHPLPVVLRRGEGVFVWDVEGKRYFDFLSGYSALSQGHCHPKI
CCCCHHCCCHHHCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHH
VKALMEQAERLTLVSRAFHADILGEYMEFTCKFFGYDKLLPMNTGAEAVETALKLCRRWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCC
YRRKGVAPERAKIVVCSENFHGRTITIISMSTDPSSYADFGPYTPGFIKIPYNNVDALAE
CCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCHHHHHH
ALKDPDAVGFLVEPIQGEAGVVVPDDGYLRACYDLCHQKNVLFIADEIQTGIGRTGKLLA
HHCCCCCCEEEEECCCCCCCEEECCCCHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
CDYEGIRPDILILGKALSGGVSPVSAVLADDEIMLTIAPGEHGSTYGGNPLAAKVAIAAL
ECCCCCCCCEEEEECHHCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
EVVRDEHLSENAFKMGELFRGEMERINNPMIKKVRGKGLLNAVVTEPKDGKTAWDICLAL
HHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHCCCCCCCCHHHHHEEEE
KENGLIAKPTHDHIIRFTPPLVITEEQMMEAIGIIRDTFAKF
CCCCEEECCCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPEDYITREEKYGAHNYHPLPVVLRRGEGVFVWDVEGKRYFDFLSGYSALSQGHCHPKI
CCCCHHCCCHHHCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHH
VKALMEQAERLTLVSRAFHADILGEYMEFTCKFFGYDKLLPMNTGAEAVETALKLCRRWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCC
YRRKGVAPERAKIVVCSENFHGRTITIISMSTDPSSYADFGPYTPGFIKIPYNNVDALAE
CCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCHHHHHH
ALKDPDAVGFLVEPIQGEAGVVVPDDGYLRACYDLCHQKNVLFIADEIQTGIGRTGKLLA
HHCCCCCCEEEEECCCCCCCEEECCCCHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
CDYEGIRPDILILGKALSGGVSPVSAVLADDEIMLTIAPGEHGSTYGGNPLAAKVAIAAL
ECCCCCCCCEEEEECHHCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
EVVRDEHLSENAFKMGELFRGEMERINNPMIKKVRGKGLLNAVVTEPKDGKTAWDICLAL
HHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHCCCCCCCCHHHHHEEEE
KENGLIAKPTHDHIIRFTPPLVITEEQMMEAIGIIRDTFAKF
CCCCEEECCCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA