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The map label for this gene is rocF [H]

Identifier: 150009270

GI number: 150009270

Start: 3173392

End: 3174288

Strand: Reverse

Name: rocF [H]

Synonym: BDI_2672

Alternate gene names: 150009270

Gene position: 3174288-3173392 (Counterclockwise)

Preceding gene: 150009271

Following gene: 150009265

Centisome position: 65.97

GC content: 51.06

Gene sequence:

>897_bases
ATGAAGATAAATGTAATAGGTGTTCCCTTGAATCTGGGATGTGACCGGGCTGGCGTAGAGCGTGCCCCGAACCACCTTCG
GGAACGGGGATTGATGGGGGTGATCCGGAAGAACGGGCATAAAGCCTTTGACTTGGGTAATTTGTATGTACCCCCTGTTA
GCGAGGCGGATAAGTTCGTACGGGGTAACAGCATGAAATATCTGGATGCGATCGTGGAGGTAAATACGAATCTGGCGGAG
TTGGTTTATGATACATTGCGTGGAGGAGCGTTCCCCTTGGTGATTGGCGGGGATCATTCGCTGGGTTTAGGTAGCGCCTC
GGGCGTGGGTAAATGTTATGATGATTTCGGTATTATCTGGCTGGACGCTCATGGGGATATCAATACCAGCGAGACTTCTC
CCAGTGGTAATATCCACGGGATGCCTTTGAGTGCGTTGATGGGGATGGGAAGCGAGGAACTGGTGAATATCTACGCTCCC
GGGAATAAGGTGAATCCGCAGAACGTATTCTTGGTCGGGACCCGCAGTCTGGATGAGGGCGAGTGGGATTTGATCGAGCG
GGAGAAGCTGAGTGTCTATACGATGGAGACGATCCATCTGAAAGGCATCGGCTTCGTAGCTGAGGATATCAAGCGGAAAT
TGAAGGAACGGAAGATCCGCAACGTGCATTTCAGCATAGACGTGGATAGCATAGACCCCCGTTTCGCTCCGGGCACGGGA
ACCCGTGTGTGTGAGGGACTGATGCCGGATGAGTTTAATAACTTCGTGGATCATATGTTGTCTACGAATCTGGTTAAGTC
GATGGATTTGGTAGAGCTGAATCCGGAGCTGGACGTGAACGAGCAGACCACAAACCTTTGTCTGCAGATCATCGATTATA
TTACCGCCCGTCTATAA

Upstream 100 bases:

>100_bases
CGATCATATCATCCGCTTCACGCCTCCTTTGGTGATTACGGAGGAGCAAATGATGGAAGCGATTGGCATTATACGAGATA
CGTTTGCTAAATTCTAGTGT

Downstream 100 bases:

>100_bases
GGAATCTAAATTCCATGGTTTATGATAAGAGTGTGAAAAGGAAGTCCCCTTGTTCCGGTTAAGACCGGATACGAGGGGAC
TTGAAAATACGATATGTCTA

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKINVIGVPLNLGCDRAGVERAPNHLRERGLMGVIRKNGHKAFDLGNLYVPPVSEADKFVRGNSMKYLDAIVEVNTNLAE
LVYDTLRGGAFPLVIGGDHSLGLGSASGVGKCYDDFGIIWLDAHGDINTSETSPSGNIHGMPLSALMGMGSEELVNIYAP
GNKVNPQNVFLVGTRSLDEGEWDLIEREKLSVYTMETIHLKGIGFVAEDIKRKLKERKIRNVHFSIDVDSIDPRFAPGTG
TRVCEGLMPDEFNNFVDHMLSTNLVKSMDLVELNPELDVNEQTTNLCLQIIDYITARL

Sequences:

>Translated_298_residues
MKINVIGVPLNLGCDRAGVERAPNHLRERGLMGVIRKNGHKAFDLGNLYVPPVSEADKFVRGNSMKYLDAIVEVNTNLAE
LVYDTLRGGAFPLVIGGDHSLGLGSASGVGKCYDDFGIIWLDAHGDINTSETSPSGNIHGMPLSALMGMGSEELVNIYAP
GNKVNPQNVFLVGTRSLDEGEWDLIEREKLSVYTMETIHLKGIGFVAEDIKRKLKERKIRNVHFSIDVDSIDPRFAPGTG
TRVCEGLMPDEFNNFVDHMLSTNLVKSMDLVELNPELDVNEQTTNLCLQIIDYITARL
>Mature_298_residues
MKINVIGVPLNLGCDRAGVERAPNHLRERGLMGVIRKNGHKAFDLGNLYVPPVSEADKFVRGNSMKYLDAIVEVNTNLAE
LVYDTLRGGAFPLVIGGDHSLGLGSASGVGKCYDDFGIIWLDAHGDINTSETSPSGNIHGMPLSALMGMGSEELVNIYAP
GNKVNPQNVFLVGTRSLDEGEWDLIEREKLSVYTMETIHLKGIGFVAEDIKRKLKERKIRNVHFSIDVDSIDPRFAPGTG
TRVCEGLMPDEFNNFVDHMLSTNLVKSMDLVELNPELDVNEQTTNLCLQIIDYITARL

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=280, Percent_Identity=33.9285714285714, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4502215, Length=299, Percent_Identity=33.1103678929766, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=24.3986254295533, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996843, Length=241, Percent_Identity=31.9502074688797, Blast_Score=120, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6325146, Length=299, Percent_Identity=29.7658862876254, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24638886, Length=288, Percent_Identity=34.0277777777778, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32783; Mature: 32783

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINVIGVPLNLGCDRAGVERAPNHLRERGLMGVIRKNGHKAFDLGNLYVPPVSEADKFV
CEEEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEHHCCCCEEEECCCEECCCCCHHHHHH
RGNSMKYLDAIVEVNTNLAELVYDTLRGGAFPLVIGGDHSLGLGSASGVGKCYDDFGIIW
CCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
LDAHGDINTSETSPSGNIHGMPLSALMGMGSEELVNIYAPGNKVNPQNVFLVGTRSLDEG
EECCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHEEEEECCCCCCCCCEEEEEEECCCCCC
EWDLIEREKLSVYTMETIHLKGIGFVAEDIKRKLKERKIRNVHFSIDVDSIDPRFAPGTG
CCCCEECCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCC
TRVCEGLMPDEFNNFVDHMLSTNLVKSMDLVELNPELDVNEQTTNLCLQIIDYITARL
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKINVIGVPLNLGCDRAGVERAPNHLRERGLMGVIRKNGHKAFDLGNLYVPPVSEADKFV
CEEEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEHHCCCCEEEECCCEECCCCCHHHHHH
RGNSMKYLDAIVEVNTNLAELVYDTLRGGAFPLVIGGDHSLGLGSASGVGKCYDDFGIIW
CCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
LDAHGDINTSETSPSGNIHGMPLSALMGMGSEELVNIYAPGNKVNPQNVFLVGTRSLDEG
EECCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHEEEEECCCCCCCCCEEEEEEECCCCCC
EWDLIEREKLSVYTMETIHLKGIGFVAEDIKRKLKERKIRNVHFSIDVDSIDPRFAPGTG
CCCCEECCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCC
TRVCEGLMPDEFNNFVDHMLSTNLVKSMDLVELNPELDVNEQTTNLCLQIIDYITARL
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]