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The map label for this gene is rnz

Identifier: 150009249

GI number: 150009249

Start: 3133394

End: 3134308

Strand: Direct

Name: rnz

Synonym: BDI_2651

Alternate gene names: 150009249

Gene position: 3133394-3134308 (Clockwise)

Preceding gene: 150009247

Following gene: 150009252

Centisome position: 65.12

GC content: 47.87

Gene sequence:

>915_bases
ATGGCTGATTTTGATATAAACATATTGGGATGCGGTTCCGCATTGCCCACGACACGCCATCTGGCGACCTCTCAAATAGT
AGATTTACGAGATAAACTATACATGATCGACTGCGGGGAAGGCACGCAAGTGCAAATGCGTCGTATGCGTATAAAATTCA
GTCGTTTAAATCATATCTTCATCTCCCACCTACACGGAGATCATTGCTTCGGGCTACCGGGATTGATCTCTACATTAGGT
ATGCTAGGACGTAACGGAGAATTGGTTATTCATGGGCCGAAAGAGATCGAGAGCTATATGCGTCCGGTACTTGATATCTT
TTGCAAAGGGTTGCCTTATGAGATCCGTTTTAACTTAATCGACCCGACAACTCATTCGTTGGTTATGGAAGATCGCTCCT
TAAGCGTTTATTCCATTCCGTTAAAGCACCGGATACCCTGTTGTGGCTATTTGTTCGCCGAGAAAGCCAAAGAAGCGCAT
ATCATCCGGGAGATGACGGATTTCTATCAGGTTCCCGTCCGTATGATGCAAGAGATCAAAAGGGGCGCTGATTTCGTCAC
CCCGGAAGGAGAGGTAATCCCGAATGCCCGCTTAACCCGCCCTGCCGTCGCTCCCAAACGGTATGCTTATTGCTCGGATA
CAGCTTTTCACCCATCTATAATCCCCATCATTGAAGGGGTGGATTTATTATACCACGAGGCGACTTTCGCTGAATGTGAC
GCCGCACGTGCGAAAGAGACCTTCCACTCTACCGCCCGCCAAGCGGCCGAGATTGCTTATAAAGCCCAAGTGAAGCGATT
GGTTATCGGTCATTACTCGGCTCGTTACGAGGATATGGCACCGTTAAAGAAAGAAGCAGACAAGATATTTCCCGGCACGA
TCTTAGGAGAGGAAGGTATGAGGCTTAGCGTATAA

Upstream 100 bases:

>100_bases
CCTCATCCTGCATACATTACACTTTGTTTTTTTGTTATTTTTCACAGAACAGAAATGCTTTTGTATTATCTTTGCACTCA
ATTATTCCCATAGACAACAA

Downstream 100 bases:

>100_bases
TCATACATCCGTTTTACGAAATAAAGCTAATTACTTTCTAATATGCAGAAAACTTTCTACATTTGTACGAATTTAGGGAC
AAGTAAATGAAGCTTATACA

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MADFDINILGCGSALPTTRHLATSQIVDLRDKLYMIDCGEGTQVQMRRMRIKFSRLNHIFISHLHGDHCFGLPGLISTLG
MLGRNGELVIHGPKEIESYMRPVLDIFCKGLPYEIRFNLIDPTTHSLVMEDRSLSVYSIPLKHRIPCCGYLFAEKAKEAH
IIREMTDFYQVPVRMMQEIKRGADFVTPEGEVIPNARLTRPAVAPKRYAYCSDTAFHPSIIPIIEGVDLLYHEATFAECD
AARAKETFHSTARQAAEIAYKAQVKRLVIGHYSARYEDMAPLKKEADKIFPGTILGEEGMRLSV

Sequences:

>Translated_304_residues
MADFDINILGCGSALPTTRHLATSQIVDLRDKLYMIDCGEGTQVQMRRMRIKFSRLNHIFISHLHGDHCFGLPGLISTLG
MLGRNGELVIHGPKEIESYMRPVLDIFCKGLPYEIRFNLIDPTTHSLVMEDRSLSVYSIPLKHRIPCCGYLFAEKAKEAH
IIREMTDFYQVPVRMMQEIKRGADFVTPEGEVIPNARLTRPAVAPKRYAYCSDTAFHPSIIPIIEGVDLLYHEATFAECD
AARAKETFHSTARQAAEIAYKAQVKRLVIGHYSARYEDMAPLKKEADKIFPGTILGEEGMRLSV
>Mature_303_residues
ADFDINILGCGSALPTTRHLATSQIVDLRDKLYMIDCGEGTQVQMRRMRIKFSRLNHIFISHLHGDHCFGLPGLISTLGM
LGRNGELVIHGPKEIESYMRPVLDIFCKGLPYEIRFNLIDPTTHSLVMEDRSLSVYSIPLKHRIPCCGYLFAEKAKEAHI
IREMTDFYQVPVRMMQEIKRGADFVTPEGEVIPNARLTRPAVAPKRYAYCSDTAFHPSIIPIIEGVDLLYHEATFAECDA
ARAKETFHSTARQAAEIAYKAQVKRLVIGHYSARYEDMAPLKKEADKIFPGTILGEEGMRLSV

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family

Homologues:

Organism=Homo sapiens, GI8922122, Length=359, Percent_Identity=28.4122562674095, Blast_Score=129, Evalue=5e-30,
Organism=Escherichia coli, GI87082078, Length=302, Percent_Identity=32.7814569536424, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNZ_PARD8 (A6LFA6)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303992.1
- ProteinModelPortal:   A6LFA6
- SMR:   A6LFA6
- STRING:   A6LFA6
- GeneID:   5307800
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2651
- eggNOG:   COG1234
- HOGENOM:   HBG648406
- OMA:   HSTSTMA
- ProtClustDB:   PRK00055
- BioCyc:   PDIS435591:BDI_2651-MONOMER
- HAMAP:   MF_01818
- InterPro:   IPR001279
- InterPro:   IPR013471
- TIGRFAMs:   TIGR02651

Pfam domain/function: PF00753 Lactamase_B

EC number: =3.1.26.11

Molecular weight: Translated: 34327; Mature: 34196

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFDINILGCGSALPTTRHLATSQIVDLRDKLYMIDCGEGTQVQMRRMRIKFSRLNHIF
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
ISHLHGDHCFGLPGLISTLGMLGRNGELVIHGPKEIESYMRPVLDIFCKGLPYEIRFNLI
HHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEEE
DPTTHSLVMEDRSLSVYSIPLKHRIPCCGYLFAEKAKEAHIIREMTDFYQVPVRMMQEIK
CCCCHHEEEECCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGADFVTPEGEVIPNARLTRPAVAPKRYAYCSDTAFHPSIIPIIEGVDLLYHEATFAECD
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHHH
AARAKETFHSTARQAAEIAYKAQVKRLVIGHYSARYEDMAPLKKEADKIFPGTILGEEGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHCCCCEEECCCCC
RLSV
EECC
>Mature Secondary Structure 
ADFDINILGCGSALPTTRHLATSQIVDLRDKLYMIDCGEGTQVQMRRMRIKFSRLNHIF
CCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
ISHLHGDHCFGLPGLISTLGMLGRNGELVIHGPKEIESYMRPVLDIFCKGLPYEIRFNLI
HHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEEE
DPTTHSLVMEDRSLSVYSIPLKHRIPCCGYLFAEKAKEAHIIREMTDFYQVPVRMMQEIK
CCCCHHEEEECCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGADFVTPEGEVIPNARLTRPAVAPKRYAYCSDTAFHPSIIPIIEGVDLLYHEATFAECD
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHHH
AARAKETFHSTARQAAEIAYKAQVKRLVIGHYSARYEDMAPLKKEADKIFPGTILGEEGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHCCCCEEECCCCC
RLSV
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA