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The map label for this gene is arcB [H]

Identifier: 150009215

GI number: 150009215

Start: 3094155

End: 3095507

Strand: Reverse

Name: arcB [H]

Synonym: BDI_2617

Alternate gene names: 150009215

Gene position: 3095507-3094155 (Counterclockwise)

Preceding gene: 150009216

Following gene: 150009214

Centisome position: 64.34

GC content: 47.67

Gene sequence:

>1353_bases
TTGGAAAGGAAGTATAATGGGGAGGGAAAGATTTTTCCGGTAAAACGTCATCGTTGCTTGATGAGTTGCTATTATTGCGA
GCTGTATACCATGAAAGGGAATTCGGGAAAGGCACAGGCGTATTTGGATCAGGCGACCGCTTATTTGGATAGTTCTTTTG
GGGATAGGGTGGAGGCTCAATATCTGCGGACAAAATCATTTTATTATTGGAAGGAGAAAGATTATAGGCATGCGTTGTCC
GCCGTCAATCTGGCTTTAAAGATCAATCGTGATCTGGATAAGTTGGAGATGAAGAAAGCGGTATTGCAATCGTCCGGCCA
ATTGCAAGAGGCGGTCACTATCTATGAGGAGATCATCAATAAGACGGAGACGATCAACACGGATGCCTTCGACCGGCAAA
TCGAGCAACTCCGTGTATTGAATGACTTGAATGACCTGGAAAAGCAAGATCGGGAGTTGAAGCTGAAATCGGAGCAAGAA
GCTTTGAAGCAGAAGCAGATTGTCGTATCTATCGGTCTTCTATTGGTCTTGATGGGCCTACTCTATATGTTGTGGCGTAT
TTATATGCATACTAAGCGGTTGAGAAATGAGTTGCTTCAGGAGAAAGACTCCTTGACCGCTTCGGAGAAGCAACTGCGGG
TCGTGACGAAAGAGGCGGAGGCGGCGAACAAGAAAAAAAGCGCCTTTATCGCCAATATCAGCCATGAGGTGCGTACGCCG
TTGAACGCCATTGTCGGGTTCTCGGAATTATTGGCGAGTAGCGAGTATAGCGAGGAGGAGAAGATCCGGTTTGCCGGGGA
GGTGAACCATAGTTCCGAGTTGCTATTGAATCTGGTGAACGATGTCCTGGATTTATCCCGTTTGGAATCCGGCAAGATCA
AGTTCAGCGTGAAGCCAAACGATCTGGTCGCCTGTTGCCAGAGGGCGTTGGATTCGATTCGCCATCGGGTGAAGCCCGGG
GTCCGATTGACGTTTACTCCCTCGATTGAATCTTATACCTTGAATACGGATGCCTTGCGTTTACAGCAGTTGCTGACTAA
CTTGTTGTCGAATGCCGCTAAATTCACCTCCGAGGGAGAGATCAATCTCTCGTTTACCGTGGATGAGGGCAAGGAGGAGG
TCTGTTTCTCCGTTACGGATACGGGCTGCGGGATCCCGGAGGATAAGTGCGAAAAGATATTCGAGCGTTTTGAGAAACTG
GACGACTTTATTCAAGGTACCGGCCTAGGACTATCTGTTTGCCAGATCATCTCGGAGCAGCTTAATGGCTCTTTATCGGT
GGACATCTCTTATAAGGATGGAGCCCGGTTTGTCTTTATACATCCAACGAATTTAATTGAGACCCCCATATGA

Upstream 100 bases:

>100_bases
TACGATGCGATGGCTGGCTTGAGTCGTTATTACCCTGCTATTAGGACGTTTGTCCGAGTCGGGGGCGCTCTTGAAACAGT
ATGATCATTTATTGGATTCC

Downstream 100 bases:

>100_bases
GACTGAAGAATCGACTCAATAACTGGATATCCATACGTATGGGGATGGTCATCGTGATCTTCCTAGGCGTATCTTGCGGT
TCGATGAGATCTTCCACACC

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MERKYNGEGKIFPVKRHRCLMSCYYCELYTMKGNSGKAQAYLDQATAYLDSSFGDRVEAQYLRTKSFYYWKEKDYRHALS
AVNLALKINRDLDKLEMKKAVLQSSGQLQEAVTIYEEIINKTETINTDAFDRQIEQLRVLNDLNDLEKQDRELKLKSEQE
ALKQKQIVVSIGLLLVLMGLLYMLWRIYMHTKRLRNELLQEKDSLTASEKQLRVVTKEAEAANKKKSAFIANISHEVRTP
LNAIVGFSELLASSEYSEEEKIRFAGEVNHSSELLLNLVNDVLDLSRLESGKIKFSVKPNDLVACCQRALDSIRHRVKPG
VRLTFTPSIESYTLNTDALRLQQLLTNLLSNAAKFTSEGEINLSFTVDEGKEEVCFSVTDTGCGIPEDKCEKIFERFEKL
DDFIQGTGLGLSVCQIISEQLNGSLSVDISYKDGARFVFIHPTNLIETPI

Sequences:

>Translated_450_residues
MERKYNGEGKIFPVKRHRCLMSCYYCELYTMKGNSGKAQAYLDQATAYLDSSFGDRVEAQYLRTKSFYYWKEKDYRHALS
AVNLALKINRDLDKLEMKKAVLQSSGQLQEAVTIYEEIINKTETINTDAFDRQIEQLRVLNDLNDLEKQDRELKLKSEQE
ALKQKQIVVSIGLLLVLMGLLYMLWRIYMHTKRLRNELLQEKDSLTASEKQLRVVTKEAEAANKKKSAFIANISHEVRTP
LNAIVGFSELLASSEYSEEEKIRFAGEVNHSSELLLNLVNDVLDLSRLESGKIKFSVKPNDLVACCQRALDSIRHRVKPG
VRLTFTPSIESYTLNTDALRLQQLLTNLLSNAAKFTSEGEINLSFTVDEGKEEVCFSVTDTGCGIPEDKCEKIFERFEKL
DDFIQGTGLGLSVCQIISEQLNGSLSVDISYKDGARFVFIHPTNLIETPI
>Mature_450_residues
MERKYNGEGKIFPVKRHRCLMSCYYCELYTMKGNSGKAQAYLDQATAYLDSSFGDRVEAQYLRTKSFYYWKEKDYRHALS
AVNLALKINRDLDKLEMKKAVLQSSGQLQEAVTIYEEIINKTETINTDAFDRQIEQLRVLNDLNDLEKQDRELKLKSEQE
ALKQKQIVVSIGLLLVLMGLLYMLWRIYMHTKRLRNELLQEKDSLTASEKQLRVVTKEAEAANKKKSAFIANISHEVRTP
LNAIVGFSELLASSEYSEEEKIRFAGEVNHSSELLLNLVNDVLDLSRLESGKIKFSVKPNDLVACCQRALDSIRHRVKPG
VRLTFTPSIESYTLNTDALRLQQLLTNLLSNAAKFTSEGEINLSFTVDEGKEEVCFSVTDTGCGIPEDKCEKIFERFEKL
DDFIQGTGLGLSVCQIISEQLNGSLSVDISYKDGARFVFIHPTNLIETPI

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=33.7078651685393, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=33.7254901960784, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081816, Length=285, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=29.045643153527, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=31.0483870967742, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788393, Length=213, Percent_Identity=30.5164319248826, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790436, Length=294, Percent_Identity=24.8299319727891, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786600, Length=257, Percent_Identity=26.4591439688716, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790861, Length=286, Percent_Identity=27.6223776223776, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=28.6995515695067, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790551, Length=200, Percent_Identity=28.5, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=254, Percent_Identity=26.7716535433071, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=28.3842794759825, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=28.8888888888889, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51265; Mature: 51265

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKYNGEGKIFPVKRHRCLMSCYYCELYTMKGNSGKAQAYLDQATAYLDSSFGDRVEAQ
CCCCCCCCCCEEEHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHH
YLRTKSFYYWKEKDYRHALSAVNLALKINRDLDKLEMKKAVLQSSGQLQEAVTIYEEIIN
HHHHCCEEEECCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KTETINTDAFDRQIEQLRVLNDLNDLEKQDRELKLKSEQEALKQKQIVVSIGLLLVLMGL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LYMLWRIYMHTKRLRNELLQEKDSLTASEKQLRVVTKEAEAANKKKSAFIANISHEVRTP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHEECCHHHHHH
LNAIVGFSELLASSEYSEEEKIRFAGEVNHSSELLLNLVNDVLDLSRLESGKIKFSVKPN
HHHHHHHHHHHHCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCH
DLVACCQRALDSIRHRVKPGVRLTFTPSIESYTLNTDALRLQQLLTNLLSNAAKFTSEGE
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCC
INLSFTVDEGKEEVCFSVTDTGCGIPEDKCEKIFERFEKLDDFIQGTGLGLSVCQIISEQ
EEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LNGSLSVDISYKDGARFVFIHPTNLIETPI
CCCCEEEEEEECCCCEEEEECCCHHCCCCC
>Mature Secondary Structure
MERKYNGEGKIFPVKRHRCLMSCYYCELYTMKGNSGKAQAYLDQATAYLDSSFGDRVEAQ
CCCCCCCCCCEEEHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHH
YLRTKSFYYWKEKDYRHALSAVNLALKINRDLDKLEMKKAVLQSSGQLQEAVTIYEEIIN
HHHHCCEEEECCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KTETINTDAFDRQIEQLRVLNDLNDLEKQDRELKLKSEQEALKQKQIVVSIGLLLVLMGL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LYMLWRIYMHTKRLRNELLQEKDSLTASEKQLRVVTKEAEAANKKKSAFIANISHEVRTP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHEECCHHHHHH
LNAIVGFSELLASSEYSEEEKIRFAGEVNHSSELLLNLVNDVLDLSRLESGKIKFSVKPN
HHHHHHHHHHHHCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCH
DLVACCQRALDSIRHRVKPGVRLTFTPSIESYTLNTDALRLQQLLTNLLSNAAKFTSEGE
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCC
INLSFTVDEGKEEVCFSVTDTGCGIPEDKCEKIFERFEKLDDFIQGTGLGLSVCQIISEQ
EEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LNGSLSVDISYKDGARFVFIHPTNLIETPI
CCCCEEEEEEECCCCEEEEECCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]