Click here to switch to the map view.

The map label for this gene is barA [H]

Identifier: 150009214

GI number: 150009214

Start: 3092014

End: 3094158

Strand: Reverse

Name: barA [H]

Synonym: BDI_2616

Alternate gene names: 150009214

Gene position: 3094158-3092014 (Counterclockwise)

Preceding gene: 150009215

Following gene: 150009211

Centisome position: 64.31

GC content: 46.9

Gene sequence:

>2145_bases
ATGAGACTGAAGAATCGACTCAATAACTGGATATCCATACGTATGGGGATGGTCATCGTGATCTTCCTAGGCGTATCTTG
CGGTTCGATGAGATCTTCCACACCTCCTCCCGCCAAGGATCGTTTAACGGAGATCGACAGCTTGGAGAGGTTATTGCCGG
ACTGCCCGACAATAGCGTCTACCTTGCCCTTATTGCGGCGGTTGGCATTCCTGTACCAGCAGCAATCCGAGATGAAGGTT
TATAATGAACGTCTTTATGAAAATGCGATGGCGGTGGATTCTATATCTGTCGCATACTTGGGATTGAAGAACTTAGCCGA
ATATTATTACGATCAGTCTGTACGTGATAGTTTGGAATATTATTGTTCTCTCGTAGACTCCATAGCCAAGGCCCGGCATG
AATACCCGAATGTGTTGTTTGACGTGAAGAGCCTTTCCAGCCAAGATCTCCTTTGGCTTGGGAATTATGAGCTGGCGATG
AGCGAAGCTATGGATCTGTATCGGTTGGCGAGCAACTTGGATCATAGATATGGCTTGCTCCGTTGCTCGGAGACATTAGG
ATTGATTTACCAACGAATCCGGAGGGATAGCGACGCTGTTGTCTCTTTTCAGGAAAGCCTTGATTTATTGAAGGATATAA
AGGATGTGCCGGATATCATGGATACTAAGGTCCGGTTAACTTCTTATCAATTGGAGAGTAGCGTACGGACGAAGCAATAT
GCGTCGACGGAACGGATCTTAGGGCAATATATGGCTTTGCTCGATGAGCAGTATAAGATCTACCAAGAGAAAAACGATCT
TTTGTCTATTAAAAGAGAATATTGGTTACTTTATTCTTTTTACACGAGTTTTTATCTTTCGCAAGGAGACTTGGAGAATG
CCAAGCGTTCGTTGGATCAAGCCTCTTCTTATGCGGATAGTAATTGGGTTGAGGGAGATTATGCGATCAATACCTACCTG
ACGGTTAAGGCCCGTTATCATAAGGCGGCAGGAGACATTCCGCTGGCGCTTCATTGTATAAATGAAGTGCTGGAGACCGA
GCGGCTGCCCGAGGATATCCAGTTCAAGGCGGATATCTTGAAGGAACAGGGACAACTTGGGGAGGTCATGGCTCTATATG
ACGAACTTTATAGTACGCTGACGAAAAGGCGGGGAACTTCTTTTCTCCGGCAGGTAAACCAATTGCGTACCTTGCATGAG
CTGCATGAAAAGGAGTTGAAAGAAACGGAATTGAAGGAGGCCGGGCAACGCATCGCCCGGAAACAGGATCTGCTGATCTT
TATCCTATCCATATCGGTCGTGCTGTTGATCCTTCTCTATGTCCTGTTTTTGTACTACCGTCATCTACGATCCTTGAAGA
ACCAGTTGCAGCGGGAGAAAGAGTTGCTTTTGGAATCTCAAAGACAGTTGATAAAGGAAAAGACCCGTGCGGAAGAGGCT
AGCTTGATGAAAAGCGCTTTCCTTGCGAATATGAGCCACGAGGTCCGGACTCCGTTAAATGCTATCGTGGGGTTCTCCGG
TTTATTGGTGGAACCTTCTACCGATGAGGAGGAGCGGAAGGAATATTCGTCTATCATCCGGAACAACACGGATCTGATGT
TGAATCTGGTAAACGACGTATTGGACTTATCCCGGATGGAGACCGGAGACCTTCATTTTGACATCAAGGATCATCTGCTT
TTAGTATGTTGCCAAATGGCTTTGGAGAGTGTACGCCATCGGATACCGGATGGGGTTAAATTGACTTTTTCTCCCGCCGG
GGAACCAATCGTGGTACATGTAGATAATCTGCGCCTGCAACAACTGTTGACAAACCTGTTGACAAACGCCGCTAAATTTA
CGGAGAAAGGCGAGATTAATCTATCGTTTCAACTTGAGCCGGACCGGAAGAAGGTATGTATAGCCGTTACGGATACGGGC
GCCGGAATCCCCCTTGAAAAACAGGCTACCATATTCAACCGCTTTGAGAAGCTGGACGATTACAAGCCCGGCGTGGGTTT
GGGGCTCTCTATCTGTCTCCTGATCGCCGAGCGGCTGGACGGCGCCTTGTTTATCGACTCTTCGTATACAGACGGGGCTC
GCTTCGTGCTTATCCTTTCTTGTGAAATAGATTCCTCAATTTATAATCCGCCAATAGAAGTATGA

Upstream 100 bases:

>100_bases
TCTCGGAGCAGCTTAATGGCTCTTTATCGGTGGACATCTCTTATAAGGATGGAGCCCGGTTTGTCTTTATACATCCAACG
AATTTAATTGAGACCCCCAT

Downstream 100 bases:

>100_bases
GCGTGATGGCCCCTATGTATAAATAGAAAGCCAAGGCCGATGTGCTTATCGTGGGGATGGCTATCTTGGGTATCTCCATA
TATACGAAAGATACGATCGC

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MRLKNRLNNWISIRMGMVIVIFLGVSCGSMRSSTPPPAKDRLTEIDSLERLLPDCPTIASTLPLLRRLAFLYQQQSEMKV
YNERLYENAMAVDSISVAYLGLKNLAEYYYDQSVRDSLEYYCSLVDSIAKARHEYPNVLFDVKSLSSQDLLWLGNYELAM
SEAMDLYRLASNLDHRYGLLRCSETLGLIYQRIRRDSDAVVSFQESLDLLKDIKDVPDIMDTKVRLTSYQLESSVRTKQY
ASTERILGQYMALLDEQYKIYQEKNDLLSIKREYWLLYSFYTSFYLSQGDLENAKRSLDQASSYADSNWVEGDYAINTYL
TVKARYHKAAGDIPLALHCINEVLETERLPEDIQFKADILKEQGQLGEVMALYDELYSTLTKRRGTSFLRQVNQLRTLHE
LHEKELKETELKEAGQRIARKQDLLIFILSISVVLLILLYVLFLYYRHLRSLKNQLQREKELLLESQRQLIKEKTRAEEA
SLMKSAFLANMSHEVRTPLNAIVGFSGLLVEPSTDEEERKEYSSIIRNNTDLMLNLVNDVLDLSRMETGDLHFDIKDHLL
LVCCQMALESVRHRIPDGVKLTFSPAGEPIVVHVDNLRLQQLLTNLLTNAAKFTEKGEINLSFQLEPDRKKVCIAVTDTG
AGIPLEKQATIFNRFEKLDDYKPGVGLGLSICLLIAERLDGALFIDSSYTDGARFVLILSCEIDSSIYNPPIEV

Sequences:

>Translated_714_residues
MRLKNRLNNWISIRMGMVIVIFLGVSCGSMRSSTPPPAKDRLTEIDSLERLLPDCPTIASTLPLLRRLAFLYQQQSEMKV
YNERLYENAMAVDSISVAYLGLKNLAEYYYDQSVRDSLEYYCSLVDSIAKARHEYPNVLFDVKSLSSQDLLWLGNYELAM
SEAMDLYRLASNLDHRYGLLRCSETLGLIYQRIRRDSDAVVSFQESLDLLKDIKDVPDIMDTKVRLTSYQLESSVRTKQY
ASTERILGQYMALLDEQYKIYQEKNDLLSIKREYWLLYSFYTSFYLSQGDLENAKRSLDQASSYADSNWVEGDYAINTYL
TVKARYHKAAGDIPLALHCINEVLETERLPEDIQFKADILKEQGQLGEVMALYDELYSTLTKRRGTSFLRQVNQLRTLHE
LHEKELKETELKEAGQRIARKQDLLIFILSISVVLLILLYVLFLYYRHLRSLKNQLQREKELLLESQRQLIKEKTRAEEA
SLMKSAFLANMSHEVRTPLNAIVGFSGLLVEPSTDEEERKEYSSIIRNNTDLMLNLVNDVLDLSRMETGDLHFDIKDHLL
LVCCQMALESVRHRIPDGVKLTFSPAGEPIVVHVDNLRLQQLLTNLLTNAAKFTEKGEINLSFQLEPDRKKVCIAVTDTG
AGIPLEKQATIFNRFEKLDDYKPGVGLGLSICLLIAERLDGALFIDSSYTDGARFVLILSCEIDSSIYNPPIEV
>Mature_714_residues
MRLKNRLNNWISIRMGMVIVIFLGVSCGSMRSSTPPPAKDRLTEIDSLERLLPDCPTIASTLPLLRRLAFLYQQQSEMKV
YNERLYENAMAVDSISVAYLGLKNLAEYYYDQSVRDSLEYYCSLVDSIAKARHEYPNVLFDVKSLSSQDLLWLGNYELAM
SEAMDLYRLASNLDHRYGLLRCSETLGLIYQRIRRDSDAVVSFQESLDLLKDIKDVPDIMDTKVRLTSYQLESSVRTKQY
ASTERILGQYMALLDEQYKIYQEKNDLLSIKREYWLLYSFYTSFYLSQGDLENAKRSLDQASSYADSNWVEGDYAINTYL
TVKARYHKAAGDIPLALHCINEVLETERLPEDIQFKADILKEQGQLGEVMALYDELYSTLTKRRGTSFLRQVNQLRTLHE
LHEKELKETELKEAGQRIARKQDLLIFILSISVVLLILLYVLFLYYRHLRSLKNQLQREKELLLESQRQLIKEKTRAEEA
SLMKSAFLANMSHEVRTPLNAIVGFSGLLVEPSTDEEERKEYSSIIRNNTDLMLNLVNDVLDLSRMETGDLHFDIKDHLL
LVCCQMALESVRHRIPDGVKLTFSPAGEPIVVHVDNLRLQQLLTNLLTNAAKFTEKGEINLSFQLEPDRKKVCIAVTDTG
AGIPLEKQATIFNRFEKLDDYKPGVGLGLSICLLIAERLDGALFIDSSYTDGARFVLILSCEIDSSIYNPPIEV

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=34.5679012345679, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI87081816, Length=271, Percent_Identity=32.1033210332103, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=29.7959183673469, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=33.0472103004292, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=29.7413793103448, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=29.6610169491525, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=288, Percent_Identity=25.3472222222222, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=236, Percent_Identity=29.2372881355932, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=28.6307053941909, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786783, Length=309, Percent_Identity=25.8899676375405, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082128, Length=307, Percent_Identity=28.0130293159609, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787374, Length=305, Percent_Identity=26.5573770491803, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81963; Mature: 81963

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50109 HIS_KIN ; PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKNRLNNWISIRMGMVIVIFLGVSCGSMRSSTPPPAKDRLTEIDSLERLLPDCPTIAS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
TLPLLRRLAFLYQQQSEMKVYNERLYENAMAVDSISVAYLGLKNLAEYYYDQSVRDSLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YCSLVDSIAKARHEYPNVLFDVKSLSSQDLLWLGNYELAMSEAMDLYRLASNLDHRYGLL
HHHHHHHHHHHHHHCCCCEEEHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCHHHHHHH
RCSETLGLIYQRIRRDSDAVVSFQESLDLLKDIKDVPDIMDTKVRLTSYQLESSVRTKQY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHH
ASTERILGQYMALLDEQYKIYQEKNDLLSIKREYWLLYSFYTSFYLSQGDLENAKRSLDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ASSYADSNWVEGDYAINTYLTVKARYHKAAGDIPLALHCINEVLETERLPEDIQFKADIL
HHHCCCCCCCCCCEEEEEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
KEQGQLGEVMALYDELYSTLTKRRGTSFLRQVNQLRTLHELHEKELKETELKEAGQRIAR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQDLLIFILSISVVLLILLYVLFLYYRHLRSLKNQLQREKELLLESQRQLIKEKTRAEEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLMKSAFLANMSHEVRTPLNAIVGFSGLLVEPSTDEEERKEYSSIIRNNTDLMLNLVNDV
HHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LDLSRMETGDLHFDIKDHLLLVCCQMALESVRHRIPDGVKLTFSPAGEPIVVHVDNLRLQ
HHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCHHHH
QLLTNLLTNAAKFTEKGEINLSFQLEPDRKKVCIAVTDTGAGIPLEKQATIFNRFEKLDD
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHC
YKPGVGLGLSICLLIAERLDGALFIDSSYTDGARFVLILSCEIDSSIYNPPIEV
CCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRLKNRLNNWISIRMGMVIVIFLGVSCGSMRSSTPPPAKDRLTEIDSLERLLPDCPTIAS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
TLPLLRRLAFLYQQQSEMKVYNERLYENAMAVDSISVAYLGLKNLAEYYYDQSVRDSLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YCSLVDSIAKARHEYPNVLFDVKSLSSQDLLWLGNYELAMSEAMDLYRLASNLDHRYGLL
HHHHHHHHHHHHHHCCCCEEEHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCHHHHHHH
RCSETLGLIYQRIRRDSDAVVSFQESLDLLKDIKDVPDIMDTKVRLTSYQLESSVRTKQY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHH
ASTERILGQYMALLDEQYKIYQEKNDLLSIKREYWLLYSFYTSFYLSQGDLENAKRSLDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ASSYADSNWVEGDYAINTYLTVKARYHKAAGDIPLALHCINEVLETERLPEDIQFKADIL
HHHCCCCCCCCCCEEEEEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
KEQGQLGEVMALYDELYSTLTKRRGTSFLRQVNQLRTLHELHEKELKETELKEAGQRIAR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQDLLIFILSISVVLLILLYVLFLYYRHLRSLKNQLQREKELLLESQRQLIKEKTRAEEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLMKSAFLANMSHEVRTPLNAIVGFSGLLVEPSTDEEERKEYSSIIRNNTDLMLNLVNDV
HHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LDLSRMETGDLHFDIKDHLLLVCCQMALESVRHRIPDGVKLTFSPAGEPIVVHVDNLRLQ
HHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCHHHH
QLLTNLLTNAAKFTEKGEINLSFQLEPDRKKVCIAVTDTGAGIPLEKQATIFNRFEKLDD
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHC
YKPGVGLGLSICLLIAERLDGALFIDSSYTDGARFVLILSCEIDSSIYNPPIEV
CCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]