Click here to switch to the map view.

The map label for this gene is lrgA [H]

Identifier: 150009184

GI number: 150009184

Start: 3064504

End: 3064842

Strand: Direct

Name: lrgA [H]

Synonym: BDI_2586

Alternate gene names: 150009184

Gene position: 3064504-3064842 (Clockwise)

Preceding gene: 150009183

Following gene: 150009185

Centisome position: 63.69

GC content: 43.36

Gene sequence:

>339_bases
ATGCTAACAGAAGCATTTTACATTCTCTTCTTCTATTTCACGGGAGAGTTTATCAGCTACTTTATCGACGGTTTCATACC
GGGTAGCGTAATTGGGATGGTGCTATTATTTTTAGCCCTCGCGTTCAAGAAAGTAAAACCTGAAAAGGTGAAACGTCTTT
CCACGGTTCTTACCCAAAACATGGGATTATTCTTCGTTCCAGCTGGTGTAGGGCTTATGAATTCCTTCGGGATCATCTCC
GAGTATTGGGCAGTCCTGCTGATCGCTTCCGTAGTAAGTACAATTTTAGTCATCGCCAGCGTAGCGTTGGTGCAACAAAA
ACTGGAAAAGGGGAAATAG

Upstream 100 bases:

>100_bases
GACGGACGCCGTCCCTACAATGTTAAAATAATATGTTATAGAACATATCTACGAAATAGCTGTTATCTTTGTAGCGGTTA
TCAAAAAAGGTAGAAAAACT

Downstream 100 bases:

>100_bases
ACCATGGATAATCTGGCGCATTCCGAGATTTTCGCTCTTACCTTGGTAATTGGTACCTACCTGACTTCCTTGGCTCTTTA
CAAGAAAGTCCATATCAGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MLTEAFYILFFYFTGEFISYFIDGFIPGSVIGMVLLFLALAFKKVKPEKVKRLSTVLTQNMGLFFVPAGVGLMNSFGIIS
EYWAVLLIASVVSTILVIASVALVQQKLEKGK

Sequences:

>Translated_112_residues
MLTEAFYILFFYFTGEFISYFIDGFIPGSVIGMVLLFLALAFKKVKPEKVKRLSTVLTQNMGLFFVPAGVGLMNSFGIIS
EYWAVLLIASVVSTILVIASVALVQQKLEKGK
>Mature_112_residues
MLTEAFYILFFYFTGEFISYFIDGFIPGSVIGMVLLFLALAFKKVKPEKVKRLSTVLTQNMGLFFVPAGVGLMNSFGIIS
EYWAVLLIASVVSTILVIASVALVQQKLEKGK

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in p

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. LrgA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 12396; Mature: 12396

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTEAFYILFFYFTGEFISYFIDGFIPGSVIGMVLLFLALAFKKVKPEKVKRLSTVLTQN
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
MGLFFVPAGVGLMNSFGIISEYWAVLLIASVVSTILVIASVALVQQKLEKGK
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTEAFYILFFYFTGEFISYFIDGFIPGSVIGMVLLFLALAFKKVKPEKVKRLSTVLTQN
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
MGLFFVPAGVGLMNSFGIISEYWAVLLIASVVSTILVIASVALVQQKLEKGK
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA