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The map label for this gene is mraY

Identifier: 150009089

GI number: 150009089

Start: 2935227

End: 2936486

Strand: Reverse

Name: mraY

Synonym: BDI_2490

Alternate gene names: 150009089

Gene position: 2936486-2935227 (Counterclockwise)

Preceding gene: 150009090

Following gene: 150009088

Centisome position: 61.03

GC content: 47.54

Gene sequence:

>1260_bases
ATGCTTTATTATCTTTTTAATTATTTGGATCAGTTGGATTTCCCGGGAGCGGGTATGTTTAAGTACGTATCTTTCCGCTC
GGGGTTGGCCTTGATCTTGTCCTTGTTTATCTCTACGGCGATCGGCCGGCGTATCATCGATAAGTTGCAAATGTTGCAGA
TCGGCGAGACGGTGAGAAATCTTGGGCTGGAGGGCCAGATGAGCAAGAAGGGAACGCCGACGATGGGAGGTATTATCATT
ATTATCGCTATATTGATCCCGACTTTACTGTGTGCCAAGCTGAATAATATCTATGTGATATTGATGTTGGTGACTACGGT
CTGGCTGGGTGCCTTGGGATTCGCGGATGATTATATCAAGGTATTCAAGAAGAATAAGGAAGGTATGCACGGACGTTTCA
AGATCGTCGGGCAGGTAGGACTGGGCTTGATCGTTGGCTTGGTATTGTTCATGAGCCCGGATGTGGTGATCAAGGAGAAT
ATGGAGGTGCGCCATGATAACGTGATCGAGGAGGTGCGTTATCATACGGTGGAGACCAAATCGACAAAGACGACCATCCC
GTTCTTGAAAAACAATAATTTCGATTACGCCAATTTGGTGAACTGGGCGGGCGATTATAAGGAGGAGGCCGCATGGCTGG
TGTTCGTGCTGATGGTGATCTTTGTGGTGACAGCCGTGTCGAACGGAGCCAATATGACGGATGGACTGGACGGCTTGGCT
GCCGGAACATCGGCGATCATTGGGGTGGCTCTCGGTATTTTGGCCTATATGTCATCCCACTTTGAGTTCGCCTCGTTCTT
GAATATCATGTTTATACCCGGTGCGGAGGAGTTGGTGGTTTATGCCGCTGCCTTTATCGGTGCCACGGTCGGTTTCTTAT
GGTACAACTCATATCCGGCCCAAGTATTTATGGGAGATACGGGGAGCTTGACCTTGGGAGGTATTATCGCTGTTTTCGCG
ATCATCATCCGTAAGGAGTTGTTGATTCCGATCCTTTGCGGTATTTTCTTGGTGGAGAATATATCGGTCATGTTGCAAGT
GGCCTACTTTAAATATACGAAGAAGAAGTATGGGGAAGGTCGCCGTATCTTCAAGATGGCTCCTTTACACCATCATTTCC
AGAAGCCGGGAAACGCAGGTATACAGGCGTTGATCCAAAAGCCGTTCAATGTCGTGCCTGAATCGAAGATCGTGGTCCGT
TTCTGGTTGATCGGTATTATTTTGGCTGTTATGACGATAGTTACGTTAAAGATGAGATAA

Upstream 100 bases:

>100_bases
GAAGACTATCAGGAGATCAAGGGGGTGAAACAGCACTTTGACGACCGTGAGAAGTTACGCGAGATTTTTTCGACACAACA
ATCATAATATTTAAGACGAC

Downstream 100 bases:

>100_bases
AAGATGAGTAAGAGAATGGTTATATTAGGGGCCGGGGAGAGTGGTGCGGGAGCCGCTGTCTTGGCGAAGGCGAAAGGATT
CGACGTGTTCGTGTCCGATA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MLYYLFNYLDQLDFPGAGMFKYVSFRSGLALILSLFISTAIGRRIIDKLQMLQIGETVRNLGLEGQMSKKGTPTMGGIII
IIAILIPTLLCAKLNNIYVILMLVTTVWLGALGFADDYIKVFKKNKEGMHGRFKIVGQVGLGLIVGLVLFMSPDVVIKEN
MEVRHDNVIEEVRYHTVETKSTKTTIPFLKNNNFDYANLVNWAGDYKEEAAWLVFVLMVIFVVTAVSNGANMTDGLDGLA
AGTSAIIGVALGILAYMSSHFEFASFLNIMFIPGAEELVVYAAAFIGATVGFLWYNSYPAQVFMGDTGSLTLGGIIAVFA
IIIRKELLIPILCGIFLVENISVMLQVAYFKYTKKKYGEGRRIFKMAPLHHHFQKPGNAGIQALIQKPFNVVPESKIVVR
FWLIGIILAVMTIVTLKMR

Sequences:

>Translated_419_residues
MLYYLFNYLDQLDFPGAGMFKYVSFRSGLALILSLFISTAIGRRIIDKLQMLQIGETVRNLGLEGQMSKKGTPTMGGIII
IIAILIPTLLCAKLNNIYVILMLVTTVWLGALGFADDYIKVFKKNKEGMHGRFKIVGQVGLGLIVGLVLFMSPDVVIKEN
MEVRHDNVIEEVRYHTVETKSTKTTIPFLKNNNFDYANLVNWAGDYKEEAAWLVFVLMVIFVVTAVSNGANMTDGLDGLA
AGTSAIIGVALGILAYMSSHFEFASFLNIMFIPGAEELVVYAAAFIGATVGFLWYNSYPAQVFMGDTGSLTLGGIIAVFA
IIIRKELLIPILCGIFLVENISVMLQVAYFKYTKKKYGEGRRIFKMAPLHHHFQKPGNAGIQALIQKPFNVVPESKIVVR
FWLIGIILAVMTIVTLKMR
>Mature_419_residues
MLYYLFNYLDQLDFPGAGMFKYVSFRSGLALILSLFISTAIGRRIIDKLQMLQIGETVRNLGLEGQMSKKGTPTMGGIII
IIAILIPTLLCAKLNNIYVILMLVTTVWLGALGFADDYIKVFKKNKEGMHGRFKIVGQVGLGLIVGLVLFMSPDVVIKEN
MEVRHDNVIEEVRYHTVETKSTKTTIPFLKNNNFDYANLVNWAGDYKEEAAWLVFVLMVIFVVTAVSNGANMTDGLDGLA
AGTSAIIGVALGILAYMSSHFEFASFLNIMFIPGAEELVVYAAAFIGATVGFLWYNSYPAQVFMGDTGSLTLGGIIAVFA
IIIRKELLIPILCGIFLVENISVMLQVAYFKYTKKKYGEGRRIFKMAPLHHHFQKPGNAGIQALIQKPFNVVPESKIVVR
FWLIGIILAVMTIVTLKMR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=419, Percent_Identity=37.2315035799523, Blast_Score=263, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PARD8 (A6LEU6)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303832.1
- STRING:   A6LEU6
- GeneID:   5307639
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2490
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   PDIS435591:BDI_2490-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 46468; Mature: 46468

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf1bee44)-; HASH(0x106fcc8c)-; HASH(0x106fcfe0)-; HASH(0x106fcba8)-; HASH(0xf606cbc)-; HASH(0x102bdee8)-; HASH(0xf8cc314)-; HASH(0x107dee24)-; HASH(0xbde18d8)-; HASH(0xbde1af4)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEEEECCHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure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CEEEEECCHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA