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The map label for this gene is clpP [H]

Identifier: 150009000

GI number: 150009000

Start: 2808764

End: 2809426

Strand: Reverse

Name: clpP [H]

Synonym: BDI_2396

Alternate gene names: 150009000

Gene position: 2809426-2808764 (Counterclockwise)

Preceding gene: 150009001

Following gene: 150008999

Centisome position: 58.39

GC content: 46.46

Gene sequence:

>663_bases
ATGGAAGATTTTAGAAAGTATGCTACAAAGCATTTAGGTATGAGTGGTACGGCTCTGGATAGTTATATGAACATCTCCAG
TAGCTATATCTCCCCGACAATTATAGAGGAACGACAGCTGAATGTCGCTCAAATGGATGTCTTCTCTCGGTTGATGATGG
ACCGTATTATTTTCTTGGGCACGCAAGTGGATGATTATACCGCTAACGTGATTCAAGCGCAGTTGTTGTATCTGGATTCC
AGTGATCCCGGAAAGGATATCTCTATTTATATCAATTCGCCGGGTGGCTCTGTATATGCGGGCTACGGCATTTATGACAC
GATGCAGTTTATCTCCAGCGACGTATCTACGATTTGTACGGGTATGGCCGCCTCTATGGCGTCTGTCTTATTGGTGGCGG
GAACCAAGGGAAAACGTTTCGGCTTGAAGCACTCCCGTGTAATGATCCATCAACCGCTTGGCGGCGTACAAGGACAGGCT
TCAGACATCGAGATTACCGCTCGCGAGATCTTGAAGGTTAAGAAAGAACTGTACACCATAATCTCGGATCATTCAGGTAG
ACCCTATGAGGAGATCGAGCGCGATGGCGACCGTGATTTCTGGATGACCGCGGAGGAAGCGAAAAAGTATGGCATGATCG
ACGATGTTTTAACACGTAAATAA

Upstream 100 bases:

>100_bases
TGTTTCTTTCAGAAATTTATTTATAACTTTGTTTTTCCGTTAAGTCACAGAGGGAAATCCCTTTTTACGTCTTCTCGGTA
AATAAAAGATAGGAGAAAAT

Downstream 100 bases:

>100_bases
CAAAAACAACAATAAGAAACTATGGCCAAAACAACAGGCGATACATGTACGTTTTGCGGCAGGAGTAGCCGTGATGTTAA
TTTGCTTATCAATGGGATCT

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MEDFRKYATKHLGMSGTALDSYMNISSSYISPTIIEERQLNVAQMDVFSRLMMDRIIFLGTQVDDYTANVIQAQLLYLDS
SDPGKDISIYINSPGGSVYAGYGIYDTMQFISSDVSTICTGMAASMASVLLVAGTKGKRFGLKHSRVMIHQPLGGVQGQA
SDIEITAREILKVKKELYTIISDHSGRPYEEIERDGDRDFWMTAEEAKKYGMIDDVLTRK

Sequences:

>Translated_220_residues
MEDFRKYATKHLGMSGTALDSYMNISSSYISPTIIEERQLNVAQMDVFSRLMMDRIIFLGTQVDDYTANVIQAQLLYLDS
SDPGKDISIYINSPGGSVYAGYGIYDTMQFISSDVSTICTGMAASMASVLLVAGTKGKRFGLKHSRVMIHQPLGGVQGQA
SDIEITAREILKVKKELYTIISDHSGRPYEEIERDGDRDFWMTAEEAKKYGMIDDVLTRK
>Mature_220_residues
MEDFRKYATKHLGMSGTALDSYMNISSSYISPTIIEERQLNVAQMDVFSRLMMDRIIFLGTQVDDYTANVIQAQLLYLDS
SDPGKDISIYINSPGGSVYAGYGIYDTMQFISSDVSTICTGMAASMASVLLVAGTKGKRFGLKHSRVMIHQPLGGVQGQA
SDIEITAREILKVKKELYTIISDHSGRPYEEIERDGDRDFWMTAEEAKKYGMIDDVLTRK

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=206, Percent_Identity=44.1747572815534, Blast_Score=183, Evalue=1e-46,
Organism=Escherichia coli, GI1786641, Length=191, Percent_Identity=56.020942408377, Blast_Score=230, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI17538017, Length=189, Percent_Identity=49.7354497354497, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI20129427, Length=203, Percent_Identity=45.8128078817734, Blast_Score=183, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 24543; Mature: 24543

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDFRKYATKHLGMSGTALDSYMNISSSYISPTIIEERQLNVAQMDVFSRLMMDRIIFLG
CCHHHHHHHHHCCCCCHHHHHHHHCHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHC
TQVDDYTANVIQAQLLYLDSSDPGKDISIYINSPGGSVYAGYGIYDTMQFISSDVSTICT
CCCCHHHHHHHEEEEEEEECCCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHH
GMAASMASVLLVAGTKGKRFGLKHSRVMIHQPLGGVQGQASDIEITAREILKVKKELYTI
HHHHHHHHHHHEECCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ISDHSGRPYEEIERDGDRDFWMTAEEAKKYGMIDDVLTRK
HHCCCCCCHHHHHCCCCCCEEEEHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MEDFRKYATKHLGMSGTALDSYMNISSSYISPTIIEERQLNVAQMDVFSRLMMDRIIFLG
CCHHHHHHHHHCCCCCHHHHHHHHCHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHC
TQVDDYTANVIQAQLLYLDSSDPGKDISIYINSPGGSVYAGYGIYDTMQFISSDVSTICT
CCCCHHHHHHHEEEEEEEECCCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHH
GMAASMASVLLVAGTKGKRFGLKHSRVMIHQPLGGVQGQASDIEITAREILKVKKELYTI
HHHHHHHHHHHEECCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ISDHSGRPYEEIERDGDRDFWMTAEEAKKYGMIDDVLTRK
HHCCCCCCHHHHHCCCCCCEEEEHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]