Click here to switch to the map view.

The map label for this gene is fkpA [C]

Identifier: 150008855

GI number: 150008855

Start: 2632059

End: 2632574

Strand: Reverse

Name: fkpA [C]

Synonym: BDI_2245

Alternate gene names: 150008855

Gene position: 2632574-2632059 (Counterclockwise)

Preceding gene: 150008859

Following gene: 150008854

Centisome position: 54.72

GC content: 41.09

Gene sequence:

>516_bases
ATGAAAGCACTTTCAATGTATGTATGGTCACTTTTAGTGATCATGATGATGGGACTTACTTCTTGTGGGGATGATGATGA
GCTTCAATTCTCGGAAGAACAATTGGCTTATATCAACAAAAACAAGGAATACATCTGGGAAAAGAAAACAGAGAAAGATG
AGATGGGTGAATTAAGATATAAGCAAGTTGTTCTAGGGGGTGATACCGCCTTATACCGGATCATTCGGAAAGAAAATGAG
TGGACAACAACACCCACGATGACTTCCGTGGTCTATTTGCTAGGTCTGGAAGGGAAGTTTATAGATGGACAGGTCTTTCA
AAAGAAACTGGATAGATCAAGTTTTTCTATGAACGGCATTATCCCGGGCTTAAGCGGTGTCTTATTGAATATCCATCTGG
ATGAGACCGTGGAGGCGATTATCCCGGCTTCGCTAGGTTATGGATATGGAGATTATAGCGGTATCCCCGGAGGTTCTACT
TTAATCTTTACTTTTACCTTGGATAAGGTCGAATGA

Upstream 100 bases:

>100_bases
TGCAAAGAACGGAAAGTTAGTTGATATAACAAAATGGATTTGTATATTCGCGCCTCGGAAATCAAGAATAATTATAATTT
AATTTTATATAGAAATCGGA

Downstream 100 bases:

>100_bases
ATATTATCAGACTAAAGGCACATTTGGTTTGATCTGACTTTTATCTTTATAAGATTTGGCACGGTTACTTAATTCCGCCA
ACGGGTTAATAGTATAAGTA

Product: putative FKBP-type peptidyl-prolyl cis-trans isomerase

Products: Peptidylproline (Omega=0) [C]

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKALSMYVWSLLVIMMMGLTSCGDDDELQFSEEQLAYINKNKEYIWEKKTEKDEMGELRYKQVVLGGDTALYRIIRKENE
WTTTPTMTSVVYLLGLEGKFIDGQVFQKKLDRSSFSMNGIIPGLSGVLLNIHLDETVEAIIPASLGYGYGDYSGIPGGST
LIFTFTLDKVE

Sequences:

>Translated_171_residues
MKALSMYVWSLLVIMMMGLTSCGDDDELQFSEEQLAYINKNKEYIWEKKTEKDEMGELRYKQVVLGGDTALYRIIRKENE
WTTTPTMTSVVYLLGLEGKFIDGQVFQKKLDRSSFSMNGIIPGLSGVLLNIHLDETVEAIIPASLGYGYGDYSGIPGGST
LIFTFTLDKVE
>Mature_171_residues
MKALSMYVWSLLVIMMMGLTSCGDDDELQFSEEQLAYINKNKEYIWEKKTEKDEMGELRYKQVVLGGDTALYRIIRKENE
WTTTPTMTSVVYLLGLEGKFIDGQVFQKKLDRSSFSMNGIIPGLSGVLLNIHLDETVEAIIPASLGYGYGDYSGIPGGST
LIFTFTLDKVE

Specific function: Ppiases Accelerate The Folding Of Proteins. It Catalyzes The Cis-Trans Isomerization Of Proline Imidic Peptide Bonds In Oligopeptides. [C]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 19248; Mature: 19248

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALSMYVWSLLVIMMMGLTSCGDDDELQFSEEQLAYINKNKEYIWEKKTEKDEMGELRY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHE
KQVVLGGDTALYRIIRKENEWTTTPTMTSVVYLLGLEGKFIDGQVFQKKLDRSSFSMNGI
EEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEECHHHHHHHHCCCCCCCCCC
IPGLSGVLLNIHLDETVEAIIPASLGYGYGDYSGIPGGSTLIFTFTLDKVE
CCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure
MKALSMYVWSLLVIMMMGLTSCGDDDELQFSEEQLAYINKNKEYIWEKKTEKDEMGELRY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHE
KQVVLGGDTALYRIIRKENEWTTTPTMTSVVYLLGLEGKFIDGQVFQKKLDRSSFSMNGI
EEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEECHHHHHHHHCCCCCCCCCC
IPGLSGVLLNIHLDETVEAIIPASLGYGYGDYSGIPGGSTLIFTFTLDKVE
CCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Peptidoproline (Omega=180) [C]

Specific reaction: Peptidoproline (Omega=180) = peptidylproline (Omega=0) [C]

General reaction: Rotation (Single bond) [C]

Inhibitor: cyclosporins [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA