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The map label for this gene is rpiA [H]

Identifier: 150008728

GI number: 150008728

Start: 2499614

End: 2500318

Strand: Direct

Name: rpiA [H]

Synonym: BDI_2118

Alternate gene names: 150008728

Gene position: 2499614-2500318 (Clockwise)

Preceding gene: 150008727

Following gene: 150008731

Centisome position: 51.95

GC content: 47.23

Gene sequence:

>705_bases
ATGAAGTGGGATCATTCATTAATCGATACGTTGGAATGGGGAAATCAGATCTCCCATAAGGAAGATAAAATAAAGATAGC
GGATCTTATCGCATCTAAAGTCGAAAACGGACAAGTCATAGGCGTTGGCTCCGGTTCGACCTCCTATCTAGCGTTGACTC
GCATAGCGGAACGTATCCGAATGGAACATCTTTCCATCTTGGCGATCCCCACTTCATTAGAAATCCGGATGACTTGCGCC
CAGCTAGGCATTCCGGTTACCAGCCTGTTTTCCCACAAGCCGGACTGGACCTTCGATGGGGCGGATGAGGTAGATTCCCA
TTTTAACTTGATCAAAGGGCGTGGAGGCGCCATGTTCAAGGAAAAACTATTGATCAGTTCCAGTCCGCAGACCTATATAC
TCGTCGATCCTTCCAAGAAAGTGGAGAGGTTGGGAGCTAAATTCCCGATCCCAGTAGAGATTTTTCCGGAAGCCCTCACC
CATGTAGAAGACAGGCTCCATCGCTTGAACCCCCGTGAGATAAAACTTCGTATGGGGCAAGGTAAGGATGGACCGATCAT
TACCGAGAATGGCAATATGATCCTTGACGTATGGATGGACTACATCCCTGAAAATACAGAATCCACCCTCAAGTCGATTA
CAGGCGTACTCGAGAGTGGACTCTTTATCAACTATAAGGTAGAAGTACTGGGACTTACTTCATGA

Upstream 100 bases:

>100_bases
ATCGCCGGACGTGTGGATAATCATATGAATACGGATTATAAAGGTTCTTTGGAGAAACTGATTGAAACTGTATTAGACCG
TATATAATAATATCAAGACC

Downstream 100 bases:

>100_bases
ATCCTTGTTGTTTCAATACCTTCAAAAGCACCTCGGAGAAATATTCACTATTCTTCTTCGTATAGCGTACGTCCGTAAAG
ACCTGCGCCAGTGTTTCCTT

Product: putative ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKWDHSLIDTLEWGNQISHKEDKIKIADLIASKVENGQVIGVGSGSTSYLALTRIAERIRMEHLSILAIPTSLEIRMTCA
QLGIPVTSLFSHKPDWTFDGADEVDSHFNLIKGRGGAMFKEKLLISSSPQTYILVDPSKKVERLGAKFPIPVEIFPEALT
HVEDRLHRLNPREIKLRMGQGKDGPIITENGNMILDVWMDYIPENTESTLKSITGVLESGLFINYKVEVLGLTS

Sequences:

>Translated_234_residues
MKWDHSLIDTLEWGNQISHKEDKIKIADLIASKVENGQVIGVGSGSTSYLALTRIAERIRMEHLSILAIPTSLEIRMTCA
QLGIPVTSLFSHKPDWTFDGADEVDSHFNLIKGRGGAMFKEKLLISSSPQTYILVDPSKKVERLGAKFPIPVEIFPEALT
HVEDRLHRLNPREIKLRMGQGKDGPIITENGNMILDVWMDYIPENTESTLKSITGVLESGLFINYKVEVLGLTS
>Mature_234_residues
MKWDHSLIDTLEWGNQISHKEDKIKIADLIASKVENGQVIGVGSGSTSYLALTRIAERIRMEHLSILAIPTSLEIRMTCA
QLGIPVTSLFSHKPDWTFDGADEVDSHFNLIKGRGGAMFKEKLLISSSPQTYILVDPSKKVERLGAKFPIPVEIFPEALT
HVEDRLHRLNPREIKLRMGQGKDGPIITENGNMILDVWMDYIPENTESTLKSITGVLESGLFINYKVEVLGLTS

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=220, Percent_Identity=38.1818181818182, Blast_Score=140, Evalue=9e-34,
Organism=Escherichia coli, GI1789280, Length=199, Percent_Identity=34.6733668341709, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17551758, Length=201, Percent_Identity=33.8308457711443, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=206, Percent_Identity=33.9805825242718, Blast_Score=105, Evalue=8e-24,
Organism=Drosophila melanogaster, GI281364072, Length=201, Percent_Identity=35.8208955223881, Blast_Score=117, Evalue=7e-27,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 26124; Mature: 26124

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWDHSLIDTLEWGNQISHKEDKIKIADLIASKVENGQVIGVGSGSTSYLALTRIAERIR
CCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
MEHLSILAIPTSLEIRMTCAQLGIPVTSLFSHKPDWTFDGADEVDSHFNLIKGRGGAMFK
HHHEEEEEECCCCEEEEEHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHEEECCCCCHHH
EKLLISSSPQTYILVDPSKKVERLGAKFPIPVEIFPEALTHVEDRLHRLNPREIKLRMGQ
HHEEECCCCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
GKDGPIITENGNMILDVWMDYIPENTESTLKSITGVLESGLFINYKVEVLGLTS
CCCCCEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHCCEEEEEEEEEEEECC
>Mature Secondary Structure
MKWDHSLIDTLEWGNQISHKEDKIKIADLIASKVENGQVIGVGSGSTSYLALTRIAERIR
CCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
MEHLSILAIPTSLEIRMTCAQLGIPVTSLFSHKPDWTFDGADEVDSHFNLIKGRGGAMFK
HHHEEEEEECCCCEEEEEHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHEEECCCCCHHH
EKLLISSSPQTYILVDPSKKVERLGAKFPIPVEIFPEALTHVEDRLHRLNPREIKLRMGQ
HHEEECCCCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
GKDGPIITENGNMILDVWMDYIPENTESTLKSITGVLESGLFINYKVEVLGLTS
CCCCCEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9419225; 9371463 [H]