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The map label for this gene is lpxA [H]

Identifier: 150008716

GI number: 150008716

Start: 2490717

End: 2491502

Strand: Direct

Name: lpxA [H]

Synonym: BDI_2106

Alternate gene names: 150008716

Gene position: 2490717-2491502 (Clockwise)

Preceding gene: 150008715

Following gene: 150008719

Centisome position: 51.77

GC content: 48.85

Gene sequence:

>786_bases
ATGAATATATCTCCTCTAGCAGTCGTTCATCCAGAGGCCCAGATCGGCCAGAATGTAACTATCGATCCGTTTGCCGTGAT
TGAGAAAGATGTCGTAATCGGTGATAATTGCCATATATATTCTCACGCCGTTATCTTGGATGGCGCACGGATTGGTAAAA
ATTGCAATATTTTCCCGGGAGCGGTCGTTGCCGGTATCCCTCAAGACATGAAATTCGCGGGGGAAACCACGACGGCGGAA
ATCGGAGATAACACGACGCTTCGCGAATGCGTGACGATCAACCGGGGTACCGCTTCCAAAGGTAAGACCGTGGTAGGTCG
CAATTGCTTAATCATGGCTTATTCGCACGTGGCCCATGATTGCGTCTTAAAAGACCATATTATCATCGGTAACGCTTCGC
AAATCGCCGGGGAGGTAGAGATTGATGATTTCGCTATCGTAAGCGGAGGTTCCTTGGTGCATCAGTTCACGCGTATATCC
AAGCACGTGATGGTACAAGGCGGTTCTCGTATCGGAAAAGATATCCCTCCTTATACCTTGATCGGCCGTGATCCGATCGT
TTATTGCGGTATCAATATCGTAGGTTTACGTCGCCGGGGATTCACGAATCAGCAGGTATTCTTGATTCAAGACATCTATC
GCACGCTGTATACCCGAGGCTTGAATAATACGGAGGCGCTGAAAGCGATCGAGACCGAGTACGAGCCTAGCGAGGAACGG
GATTTGATCCTCAATTTCATCAAGTCTTCCAGCCGGGGTATCGTAAGAGGTTCGATCGACGAATAA

Upstream 100 bases:

>100_bases
CTACCATGAAAGGGTATGTATTCGTTGGTGATAAATTGGTTAGTGAAGCCGAGTTCATGGCTCAGATTGTAAAAAACAAA
TAATAAGATAAAGTACGATA

Downstream 100 bases:

>100_bases
GCGACACAAACATCCGGACAACCAAAAACAAATCGGCGCAAATCCACATCTTACAATGAGGGGTTTGCGCCGATTCGCTA
TTTATGTCACCAAAAGGTTA

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MNISPLAVVHPEAQIGQNVTIDPFAVIEKDVVIGDNCHIYSHAVILDGARIGKNCNIFPGAVVAGIPQDMKFAGETTTAE
IGDNTTLRECVTINRGTASKGKTVVGRNCLIMAYSHVAHDCVLKDHIIIGNASQIAGEVEIDDFAIVSGGSLVHQFTRIS
KHVMVQGGSRIGKDIPPYTLIGRDPIVYCGINIVGLRRRGFTNQQVFLIQDIYRTLYTRGLNNTEALKAIETEYEPSEER
DLILNFIKSSSRGIVRGSIDE

Sequences:

>Translated_261_residues
MNISPLAVVHPEAQIGQNVTIDPFAVIEKDVVIGDNCHIYSHAVILDGARIGKNCNIFPGAVVAGIPQDMKFAGETTTAE
IGDNTTLRECVTINRGTASKGKTVVGRNCLIMAYSHVAHDCVLKDHIIIGNASQIAGEVEIDDFAIVSGGSLVHQFTRIS
KHVMVQGGSRIGKDIPPYTLIGRDPIVYCGINIVGLRRRGFTNQQVFLIQDIYRTLYTRGLNNTEALKAIETEYEPSEER
DLILNFIKSSSRGIVRGSIDE
>Mature_261_residues
MNISPLAVVHPEAQIGQNVTIDPFAVIEKDVVIGDNCHIYSHAVILDGARIGKNCNIFPGAVVAGIPQDMKFAGETTTAE
IGDNTTLRECVTINRGTASKGKTVVGRNCLIMAYSHVAHDCVLKDHIIIGNASQIAGEVEIDDFAIVSGGSLVHQFTRIS
KHVMVQGGSRIGKDIPPYTLIGRDPIVYCGINIVGLRRRGFTNQQVFLIQDIYRTLYTRGLNNTEALKAIETEYEPSEER
DLILNFIKSSSRGIVRGSIDE

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=255, Percent_Identity=38.4313725490196, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1786376, Length=219, Percent_Identity=28.7671232876712, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28432; Mature: 28432

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISPLAVVHPEAQIGQNVTIDPFAVIEKDVVIGDNCHIYSHAVILDGARIGKNCNIFPG
CCCCCEEEECCHHHHCCCCCCCHHHHEECCEEECCCCEEEEEEEEEECHHCCCCCCCCCC
AVVAGIPQDMKFAGETTTAEIGDNTTLRECVTINRGTASKGKTVVGRNCLIMAYSHVAHD
HHEECCCCHHEECCCCEEEECCCCCCEEHEEEECCCCCCCCCEEECCCEEEEEEHHHHHH
CVLKDHIIIGNASQIAGEVEIDDFAIVSGGSLVHQFTRISKHVMVQGGSRIGKDIPPYTL
HEEECEEEEECHHHHCCEEEECCEEEEECCHHHHHHHHHHHHEEEECCCCCCCCCCCEEE
IGRDPIVYCGINIVGLRRRGFTNQQVFLIQDIYRTLYTRGLNNTEALKAIETEYEPSEER
ECCCCEEEECCEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHH
DLILNFIKSSSRGIVRGSIDE
HHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure
MNISPLAVVHPEAQIGQNVTIDPFAVIEKDVVIGDNCHIYSHAVILDGARIGKNCNIFPG
CCCCCEEEECCHHHHCCCCCCCHHHHEECCEEECCCCEEEEEEEEEECHHCCCCCCCCCC
AVVAGIPQDMKFAGETTTAEIGDNTTLRECVTINRGTASKGKTVVGRNCLIMAYSHVAHD
HHEECCCCHHEECCCCEEEECCCCCCEEHEEEECCCCCCCCCEEECCCEEEEEEHHHHHH
CVLKDHIIIGNASQIAGEVEIDDFAIVSGGSLVHQFTRISKHVMVQGGSRIGKDIPPYTL
HEEECEEEEECHHHHCCEEEECCEEEEECCHHHHHHHHHHHHEEEECCCCCCCCCCCEEE
IGRDPIVYCGINIVGLRRRGFTNQQVFLIQDIYRTLYTRGLNNTEALKAIETEYEPSEER
ECCCCEEEECCEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHH
DLILNFIKSSSRGIVRGSIDE
HHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA