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The map label for this gene is ywoG [H]

Identifier: 150008644

GI number: 150008644

Start: 2397360

End: 2398535

Strand: Reverse

Name: ywoG [H]

Synonym: BDI_2032

Alternate gene names: 150008644

Gene position: 2398535-2397360 (Counterclockwise)

Preceding gene: 150008645

Following gene: 150008643

Centisome position: 49.85

GC content: 50.51

Gene sequence:

>1176_bases
ATGAGCGAGACTAAACCTGTACTTTGGAACCGGAATTTCGTCCAATGTTGTATCTCTTACTTCTTGATGAATTTCGCCTT
TTATATGTTGATGCCTACTATGCCGGTCTATCTGGTGGAAGAGTTGGGCATCAGCACGTCCGAGGTGGGGATGGTCTTGT
CTAGCTATACGATCGGGTTGCTGTGCGTGCGCCCGTTCTCGGGATATCTGGTGGATTGTTTCTCCCGCAAACCGTTATAT
GTATTCGCCTTCACGATATTCGCCTGTTTGTTTGCCGGTTATTGGTTTGCTATGACAGTCTATACGATCATGGCGGTTCG
TTTCATCCAAGGCGGGTTTATGGGACTGACCTCAGTCTCTGGCAATACGATTACGATAGACGTGATCCCTTCCAAGCGAA
GAGGAGAGGGCATGGGCTTTTACGGATTGACGATCAATCTCGCCATGTCTTTGGCTCCTTTGGTGGCGGTCGGGCTGTAC
GATCGGCATGGTTTCTTCTGGATCATAGGGGTCGCTTTGGTGATCGCATTGGTCGGGATCGGCTCCGTCGGGCTGATCTG
TTATCCGAAACGGGAGAAAGTGCCTCGTCCGGCCTTCTCGTTGGATCGTTTTATCTTGGTAAAAGCGCTTCCTGCGGCCT
TGGCCTATTTGCTGGTCGCTATACCTTATGGGATGTTGCTCTCGTTCGTGGTATTATATGGTAAAGAGATCGAGGTGCCG
AACCCAGGCTATTTCTTTATATGTATGGCGATCGGTGTAGGGACGGCCCGTTTGATTTCCGGACGGTTGGTGGACCATGG
CAAGATCCATGTCGTGTCCATCGTATCCTTGGTCTCTTTAGCGATCTCGTTTTCCGTGTTCGCTACCGTACATACATCAT
TTGTCTTTTTCGCTTGCGCCTTGGCGATCGGTATCGGTTTTGGCGTGAGTGTACCGGCTTTTCAATGTCTTTTCGTGAAT
GTCGCTCCGCACCATATGCGCGGTACGGCCACTTCTACCTACTTGACCTCTTTCGATTTCGGGATGGGGATCGGGATGCT
GTCCGCCGGCTTTATCGCTACCCATACCAATCTGGCTACCGCCTACGGAGTCGGGGCGGTTTGTTGCCTTCTTTCCTTAT
TCGTCTATATCCGCTTGGTAAAAGCCTCGTACGAGAGGAATAAGCTGATTTCTTGA

Upstream 100 bases:

>100_bases
ATGGCTAAATCTCAACGGATCACCCAAGTCATGGAAGAGATCGACGAGAAAACGATGCGCTGGCTGGAGTTGAGTGAGCT
GGCATAAGTAATAAAGAGGA

Downstream 100 bases:

>100_bases
TCCGCTTGATTCCCGGTTTCGTCTAAACCTACGGCGTACTTCGTCGATTCTTCCTTTTCTAGCGGGAAACCTCACCCTAT
ATTTGTATCAAAGATCACAG

Product: putative transmembrane transport protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSETKPVLWNRNFVQCCISYFLMNFAFYMLMPTMPVYLVEELGISTSEVGMVLSSYTIGLLCVRPFSGYLVDCFSRKPLY
VFAFTIFACLFAGYWFAMTVYTIMAVRFIQGGFMGLTSVSGNTITIDVIPSKRRGEGMGFYGLTINLAMSLAPLVAVGLY
DRHGFFWIIGVALVIALVGIGSVGLICYPKREKVPRPAFSLDRFILVKALPAALAYLLVAIPYGMLLSFVVLYGKEIEVP
NPGYFFICMAIGVGTARLISGRLVDHGKIHVVSIVSLVSLAISFSVFATVHTSFVFFACALAIGIGFGVSVPAFQCLFVN
VAPHHMRGTATSTYLTSFDFGMGIGMLSAGFIATHTNLATAYGVGAVCCLLSLFVYIRLVKASYERNKLIS

Sequences:

>Translated_391_residues
MSETKPVLWNRNFVQCCISYFLMNFAFYMLMPTMPVYLVEELGISTSEVGMVLSSYTIGLLCVRPFSGYLVDCFSRKPLY
VFAFTIFACLFAGYWFAMTVYTIMAVRFIQGGFMGLTSVSGNTITIDVIPSKRRGEGMGFYGLTINLAMSLAPLVAVGLY
DRHGFFWIIGVALVIALVGIGSVGLICYPKREKVPRPAFSLDRFILVKALPAALAYLLVAIPYGMLLSFVVLYGKEIEVP
NPGYFFICMAIGVGTARLISGRLVDHGKIHVVSIVSLVSLAISFSVFATVHTSFVFFACALAIGIGFGVSVPAFQCLFVN
VAPHHMRGTATSTYLTSFDFGMGIGMLSAGFIATHTNLATAYGVGAVCCLLSLFVYIRLVKASYERNKLIS
>Mature_390_residues
SETKPVLWNRNFVQCCISYFLMNFAFYMLMPTMPVYLVEELGISTSEVGMVLSSYTIGLLCVRPFSGYLVDCFSRKPLYV
FAFTIFACLFAGYWFAMTVYTIMAVRFIQGGFMGLTSVSGNTITIDVIPSKRRGEGMGFYGLTINLAMSLAPLVAVGLYD
RHGFFWIIGVALVIALVGIGSVGLICYPKREKVPRPAFSLDRFILVKALPAALAYLLVAIPYGMLLSFVVLYGKEIEVPN
PGYFFICMAIGVGTARLISGRLVDHGKIHVVSIVSLVSLAISFSVFATVHTSFVFFACALAIGIGFGVSVPAFQCLFVNV
APHHMRGTATSTYLTSFDFGMGIGMLSAGFIATHTNLATAYGVGAVCCLLSLFVYIRLVKASYERNKLIS

Specific function: Involved In Sulfonamide (Sulfathiazole) And Bicyclomycin Resistance. Probable Membrane Translocase. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42642; Mature: 42511

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETKPVLWNRNFVQCCISYFLMNFAFYMLMPTMPVYLVEELGISTSEVGMVLSSYTIGL
CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHEEE
LCVRPFSGYLVDCFSRKPLYVFAFTIFACLFAGYWFAMTVYTIMAVRFIQGGFMGLTSVS
EEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GNTITIDVIPSKRRGEGMGFYGLTINLAMSLAPLVAVGLYDRHGFFWIIGVALVIALVGI
CCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
GSVGLICYPKREKVPRPAFSLDRFILVKALPAALAYLLVAIPYGMLLSFVVLYGKEIEVP
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC
NPGYFFICMAIGVGTARLISGRLVDHGKIHVVSIVSLVSLAISFSVFATVHTSFVFFACA
CCCEEEEEEEHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIGIGFGVSVPAFQCLFVNVAPHHMRGTATSTYLTSFDFGMGIGMLSAGFIATHTNLAT
HHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHCCCCHHH
AYGVGAVCCLLSLFVYIRLVKASYERNKLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SETKPVLWNRNFVQCCISYFLMNFAFYMLMPTMPVYLVEELGISTSEVGMVLSSYTIGL
CCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHEEE
LCVRPFSGYLVDCFSRKPLYVFAFTIFACLFAGYWFAMTVYTIMAVRFIQGGFMGLTSVS
EEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GNTITIDVIPSKRRGEGMGFYGLTINLAMSLAPLVAVGLYDRHGFFWIIGVALVIALVGI
CCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
GSVGLICYPKREKVPRPAFSLDRFILVKALPAALAYLLVAIPYGMLLSFVVLYGKEIEVP
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC
NPGYFFICMAIGVGTARLISGRLVDHGKIHVVSIVSLVSLAISFSVFATVHTSFVFFACA
CCCEEEEEEEHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIGIGFGVSVPAFQCLFVNVAPHHMRGTATSTYLTSFDFGMGIGMLSAGFIATHTNLAT
HHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHCCCCHHH
AYGVGAVCCLLSLFVYIRLVKASYERNKLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]