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The map label for this gene is macB [H]

Identifier: 150008584

GI number: 150008584

Start: 2333238

End: 2334509

Strand: Reverse

Name: macB [H]

Synonym: BDI_1970

Alternate gene names: 150008584

Gene position: 2334509-2333238 (Counterclockwise)

Preceding gene: 150008585

Following gene: 150008583

Centisome position: 48.52

GC content: 51.81

Gene sequence:

>1272_bases
ATGTATAAGCAGTACATCAAACAAGCGGTTCAAATGCTGCGTGAAAATACGCTCGTAAGCATAATCTCTATTTCGGGAAC
GGCCCTTGCGATCGCCATGGTGTTGGTGATGGTATTGGTGTTCCAGATTAAATCCACGGGATATGCCCCTGAGTCCAATC
GGTCTAGGTTTATGTATGTCTGGGGTACGGAAGTCGGTTCGAAATCCCCCGGAGGATCGGATCGTAATCGTGGAGGCATG
TCCAGCGAGGTCGTGAAGGAATGTTTCTATACCTTGCGGAAACCAGAGGCCGTATCCGGCTATTGTAGTGATAGCCATTC
CTTGTCATTGCCCAATAGACGGCTCTTCAAGGAGTATGAGATTTGTTATACGGACGCGGGCCATTGGAAAATATTCGACC
ATCCTTTCGTGGAAGGAGGCCCCTTTAGCGAGGCTGATTTTCAATCCGGTATACCGAAGATGGTGCTGTCGGAACAGGTG
GCGACCGATTTGTTCGGAACAGGACAGGCCGTCGGGCGGCAGGTTGTGATGGATTTTATCACTTTCACCGTCTGCGGGGT
GGTGCGTGACGTACCTTCTTCATTGATGAGCTCCTACGCTCAGGTATGGATACCCTATAGCAGCAATGAGGCCCTGACCC
GTGTAAATGGGGAGTATGGGGAGAATATGGCCGGTTATTTCAGCGTGGCCTTATTGGCTCGTTCCTCTTCCGACTTCGAT
GCCATACGCTCGGAGCTAGACCAACAGGTCCGTCGCTACAATGACAGCAAGACCGATTATAACGTAGGTTTCCCTTCCGG
GCTACTTTCCCAGTTGGATACGGCCATGGGAAGCGGCGCTTTTCAAAAGGTGGACTGGCCTACCTTCTTGGCCGGATCGG
GCGCTTTCCTATTCTTCTTGCTCTTGGTACCGGCGCTGAACTTAACGGGCGTGATCCAATCGTCCGTGCAGAAGCGGAAA
GAAGAGATCGGTTTGCGTAAGGCTTTCGGGGCTACGGGACAGAATCTTTTGATGCAGATCTTATCGGAGAACTTTGTGCT
GACCTTGATCGGCGGCGTGATCGGCATCGGCCTCTCGATGGTCTTGCTGGTGGTAGGGAAGCCTTTCATGTTGAGCGAGA
ACGTGAGCCTTACGGCGCCTATGCTCGTTAAACCGGGCTTATTTATCTCCGCCCTTATCTTTACGTTCTTGCTGAATATA
TTAAGCGCCGGGATACCGGCATGGCGTACGACAAGGCAACCGATCGTAGAAGCGTTAAAGGGGAACGAGTGA

Upstream 100 bases:

>100_bases
AAGTAGTAGGTGGCTTGGAACCGGGTGACGAGGTGGTCGTTTCCGATATGACAAGTTTCAAGGAAAAGAATAAACTGAAA
TTGAAATAACGATTCGAATT

Downstream 100 bases:

>100_bases
ATCCAATGAATGATGAACAATGAGTTGTCAATTGTCAACTATCAACTATCAACTATCAAATTATGATTAAGCATATATTT
AAAATAATATGGGCCCAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MYKQYIKQAVQMLRENTLVSIISISGTALAIAMVLVMVLVFQIKSTGYAPESNRSRFMYVWGTEVGSKSPGGSDRNRGGM
SSEVVKECFYTLRKPEAVSGYCSDSHSLSLPNRRLFKEYEICYTDAGHWKIFDHPFVEGGPFSEADFQSGIPKMVLSEQV
ATDLFGTGQAVGRQVVMDFITFTVCGVVRDVPSSLMSSYAQVWIPYSSNEALTRVNGEYGENMAGYFSVALLARSSSDFD
AIRSELDQQVRRYNDSKTDYNVGFPSGLLSQLDTAMGSGAFQKVDWPTFLAGSGAFLFFLLLVPALNLTGVIQSSVQKRK
EEIGLRKAFGATGQNLLMQILSENFVLTLIGGVIGIGLSMVLLVVGKPFMLSENVSLTAPMLVKPGLFISALIFTFLLNI
LSAGIPAWRTTRQPIVEALKGNE

Sequences:

>Translated_423_residues
MYKQYIKQAVQMLRENTLVSIISISGTALAIAMVLVMVLVFQIKSTGYAPESNRSRFMYVWGTEVGSKSPGGSDRNRGGM
SSEVVKECFYTLRKPEAVSGYCSDSHSLSLPNRRLFKEYEICYTDAGHWKIFDHPFVEGGPFSEADFQSGIPKMVLSEQV
ATDLFGTGQAVGRQVVMDFITFTVCGVVRDVPSSLMSSYAQVWIPYSSNEALTRVNGEYGENMAGYFSVALLARSSSDFD
AIRSELDQQVRRYNDSKTDYNVGFPSGLLSQLDTAMGSGAFQKVDWPTFLAGSGAFLFFLLLVPALNLTGVIQSSVQKRK
EEIGLRKAFGATGQNLLMQILSENFVLTLIGGVIGIGLSMVLLVVGKPFMLSENVSLTAPMLVKPGLFISALIFTFLLNI
LSAGIPAWRTTRQPIVEALKGNE
>Mature_423_residues
MYKQYIKQAVQMLRENTLVSIISISGTALAIAMVLVMVLVFQIKSTGYAPESNRSRFMYVWGTEVGSKSPGGSDRNRGGM
SSEVVKECFYTLRKPEAVSGYCSDSHSLSLPNRRLFKEYEICYTDAGHWKIFDHPFVEGGPFSEADFQSGIPKMVLSEQV
ATDLFGTGQAVGRQVVMDFITFTVCGVVRDVPSSLMSSYAQVWIPYSSNEALTRVNGEYGENMAGYFSVALLARSSSDFD
AIRSELDQQVRRYNDSKTDYNVGFPSGLLSQLDTAMGSGAFQKVDWPTFLAGSGAFLFFLLLVPALNLTGVIQSSVQKRK
EEIGLRKAFGATGQNLLMQILSENFVLTLIGGVIGIGLSMVLLVVGKPFMLSENVSLTAPMLVKPGLFISALIFTFLLNI
LSAGIPAWRTTRQPIVEALKGNE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=304, Percent_Identity=24.0131578947368, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46333; Mature: 46333

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKQYIKQAVQMLRENTLVSIISISGTALAIAMVLVMVLVFQIKSTGYAPESNRSRFMYV
CCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
WGTEVGSKSPGGSDRNRGGMSSEVVKECFYTLRKPEAVSGYCSDSHSLSLPNRRLFKEYE
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
ICYTDAGHWKIFDHPFVEGGPFSEADFQSGIPKMVLSEQVATDLFGTGQAVGRQVVMDFI
HEEECCCCEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TFTVCGVVRDVPSSLMSSYAQVWIPYSSNEALTRVNGEYGENMAGYFSVALLARSSSDFD
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHEECCCCCCCCHHHHHHHHHHHCCCCCHH
AIRSELDQQVRRYNDSKTDYNVGFPSGLLSQLDTAMGSGAFQKVDWPTFLAGSGAFLFFL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHH
LLVPALNLTGVIQSSVQKRKEEIGLRKAFGATGQNLLMQILSENFVLTLIGGVIGIGLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLLVVGKPFMLSENVSLTAPMLVKPGLFISALIFTFLLNILSAGIPAWRTTRQPIVEALK
HHHHHCCCCEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
GNE
CCC
>Mature Secondary Structure
MYKQYIKQAVQMLRENTLVSIISISGTALAIAMVLVMVLVFQIKSTGYAPESNRSRFMYV
CCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
WGTEVGSKSPGGSDRNRGGMSSEVVKECFYTLRKPEAVSGYCSDSHSLSLPNRRLFKEYE
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
ICYTDAGHWKIFDHPFVEGGPFSEADFQSGIPKMVLSEQVATDLFGTGQAVGRQVVMDFI
HEEECCCCEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TFTVCGVVRDVPSSLMSSYAQVWIPYSSNEALTRVNGEYGENMAGYFSVALLARSSSDFD
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHEECCCCCCCCHHHHHHHHHHHCCCCCHH
AIRSELDQQVRRYNDSKTDYNVGFPSGLLSQLDTAMGSGAFQKVDWPTFLAGSGAFLFFL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHH
LLVPALNLTGVIQSSVQKRKEEIGLRKAFGATGQNLLMQILSENFVLTLIGGVIGIGLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLLVVGKPFMLSENVSLTAPMLVKPGLFISALIFTFLLNILSAGIPAWRTTRQPIVEALK
HHHHHCCCCEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
GNE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]