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The map label for this gene is atoC [H]

Identifier: 150008563

GI number: 150008563

Start: 2309972

End: 2311342

Strand: Reverse

Name: atoC [H]

Synonym: BDI_1949

Alternate gene names: 150008563

Gene position: 2311342-2309972 (Counterclockwise)

Preceding gene: 150008564

Following gene: 150008562

Centisome position: 48.04

GC content: 51.71

Gene sequence:

>1371_bases
ATGATACTGATAATAGATGATGATGCGGCTGTTCGTTCCTCGCTTACATTCCTGCTAAAACGTGCGGGTTTCCGGCCGGA
GGCGGTTCCGGGGCCGAAGGAGGCCTTGGAGGTGGTCCGTGCCACGGCGCCGGAGCTGATCTTGATGGATATGAACTTCA
CGTTGACTACCACGGGCGAGGAGGGGATTCAATTATTGAGACAGGTGAAGATCTTTCGTCCCGATGTACCCGTGATCTTG
ATGACCGCTTGGGGATCGATCTCTTTGGCCGTGCAGGGAATGCAAGCCGGAGCCTTCGATTTTATCACGAAGCCTTGGAA
TAACTTGGTATTATTAAAATCGATCCGGACCGCCTTGGAACTGAGCGAGCAGAAGAAGGAGGCAAACGCTCCCTTGAACC
GTTCGGATGCCGATCATAAATTTCATTTTGATAAGATCGTGGGGCAAAGTGCCGCTTTGATGGATGTCTTGGGGACGGTC
TCGCGTATCGCTCCGACAAACGCCTCTGTCTTGATTACCGGCGAGAGCGGTACGGGTAAAGAGCTGATAGCGGAAGCGAT
CCATGCGAATAGCCCCCGGTCGAAAGAGGCTTTCGTAAAAGTAAACCTAGGCGGACTTTCCCAAAGTCTTTTTGAGAGCG
AGATGTTCGGACATAAGAAGGGGGCTTTTACGGACGCGTACATGGATCGGGTAGGGCGTTTCGAGATGGCGAACAAAGGT
ACGATCTTCTTGGATGAGATCGGCGATTTGGAACTGTCTTGCCAAGTAAAGCTGCTTCGGGTATTGCAAGACCAGACCTT
TGAGGTCTTGGGGGATAGCCGTCCCCGGAAGGTGGATATACGGGTCGTAAGCGCTACAAACCGGGATTTACGATCGATGG
TGGCGGACCGTACGTTCCGTGAGGATCTTTTTTACCGGATCAATTTGATCACGGTGCATTTACCCGCCTTACGTGAGCGA
AGGGAGGATATCCCATTGCTGGCCCGGTATTTCGCGGATAAGCAATCGGAGATCAATGGGCTACCGAGGGTGGAGTTCTC
ATCGGATGCCCAGACCTATTTAAGCCGTCTCCCTTTTCCCGGTAATATCCGTGAGTTGAAGAACTTGGTGGAGCGGACGA
TCCTTGTGTCGGGTAAGACGCTTTTGGATACCGCTGATTTCGAGGTTCATTGCATGAATACATCCGGTGCTAAATCGACG
ATTCCGCCTTCTTTGGAGGGCTTGACCTTGGATGAGTTGGAGAAGCAAACCATCTTACGCTCCTTGGAAGCGCATGGAGG
TAATTTATCGCATGTCGCTACGGCGTTGGGAATCAGTCGTGCCGCCTTGTACCGGAGATTAGAGAAATACGGAATCCCGA
TCGATAAATAA

Upstream 100 bases:

>100_bases
TTATTTTTATAACATCCGTAGTATAACATTGTATGATTTCTTGAATAATCGTACATTAGATGCCGATTTCGAGGAAATCG
TGAAACGATAAATTGATTAT

Downstream 100 bases:

>100_bases
GAAGAGGCAAGGATGAGGCTGAAAGGACTATTCTGGATATTGACGACGCTGCTGTTGACTATATTGGCGGTGGTGACTTA
TTATGTCTTTTATACGTCTT

Product: two-component system response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MILIIDDDAAVRSSLTFLLKRAGFRPEAVPGPKEALEVVRATAPELILMDMNFTLTTTGEEGIQLLRQVKIFRPDVPVIL
MTAWGSISLAVQGMQAGAFDFITKPWNNLVLLKSIRTALELSEQKKEANAPLNRSDADHKFHFDKIVGQSAALMDVLGTV
SRIAPTNASVLITGESGTGKELIAEAIHANSPRSKEAFVKVNLGGLSQSLFESEMFGHKKGAFTDAYMDRVGRFEMANKG
TIFLDEIGDLELSCQVKLLRVLQDQTFEVLGDSRPRKVDIRVVSATNRDLRSMVADRTFREDLFYRINLITVHLPALRER
REDIPLLARYFADKQSEINGLPRVEFSSDAQTYLSRLPFPGNIRELKNLVERTILVSGKTLLDTADFEVHCMNTSGAKST
IPPSLEGLTLDELEKQTILRSLEAHGGNLSHVATALGISRAALYRRLEKYGIPIDK

Sequences:

>Translated_456_residues
MILIIDDDAAVRSSLTFLLKRAGFRPEAVPGPKEALEVVRATAPELILMDMNFTLTTTGEEGIQLLRQVKIFRPDVPVIL
MTAWGSISLAVQGMQAGAFDFITKPWNNLVLLKSIRTALELSEQKKEANAPLNRSDADHKFHFDKIVGQSAALMDVLGTV
SRIAPTNASVLITGESGTGKELIAEAIHANSPRSKEAFVKVNLGGLSQSLFESEMFGHKKGAFTDAYMDRVGRFEMANKG
TIFLDEIGDLELSCQVKLLRVLQDQTFEVLGDSRPRKVDIRVVSATNRDLRSMVADRTFREDLFYRINLITVHLPALRER
REDIPLLARYFADKQSEINGLPRVEFSSDAQTYLSRLPFPGNIRELKNLVERTILVSGKTLLDTADFEVHCMNTSGAKST
IPPSLEGLTLDELEKQTILRSLEAHGGNLSHVATALGISRAALYRRLEKYGIPIDK
>Mature_456_residues
MILIIDDDAAVRSSLTFLLKRAGFRPEAVPGPKEALEVVRATAPELILMDMNFTLTTTGEEGIQLLRQVKIFRPDVPVIL
MTAWGSISLAVQGMQAGAFDFITKPWNNLVLLKSIRTALELSEQKKEANAPLNRSDADHKFHFDKIVGQSAALMDVLGTV
SRIAPTNASVLITGESGTGKELIAEAIHANSPRSKEAFVKVNLGGLSQSLFESEMFGHKKGAFTDAYMDRVGRFEMANKG
TIFLDEIGDLELSCQVKLLRVLQDQTFEVLGDSRPRKVDIRVVSATNRDLRSMVADRTFREDLFYRINLITVHLPALRER
REDIPLLARYFADKQSEINGLPRVEFSSDAQTYLSRLPFPGNIRELKNLVERTILVSGKTLLDTADFEVHCMNTSGAKST
IPPSLEGLTLDELEKQTILRSLEAHGGNLSHVATALGISRAALYRRLEKYGIPIDK

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=460, Percent_Identity=41.9565217391304, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1790299, Length=476, Percent_Identity=37.1848739495798, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1790437, Length=451, Percent_Identity=38.1374722838137, Blast_Score=297, Evalue=8e-82,
Organism=Escherichia coli, GI1788905, Length=449, Percent_Identity=36.0801781737194, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1789087, Length=326, Percent_Identity=44.1717791411043, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87082117, Length=329, Percent_Identity=44.3768996960486, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1789233, Length=336, Percent_Identity=38.9880952380952, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=38.801261829653, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=320, Percent_Identity=39.0625, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1787583, Length=317, Percent_Identity=34.7003154574132, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786524, Length=327, Percent_Identity=37.0030581039755, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789828, Length=309, Percent_Identity=33.6569579288026, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081858, Length=284, Percent_Identity=29.5774647887324, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788394, Length=144, Percent_Identity=28.4722222222222, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50577; Mature: 50577

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIIDDDAAVRSSLTFLLKRAGFRPEAVPGPKEALEVVRATAPELILMDMNFTLTTTGE
CEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCEEEEECCH
EGIQLLRQVKIFRPDVPVILMTAWGSISLAVQGMQAGAFDFITKPWNNLVLLKSIRTALE
HHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHCCCCCEEHHHHHHHHHH
LSEQKKEANAPLNRSDADHKFHFDKIVGQSAALMDVLGTVSRIAPTNASVLITGESGTGK
HHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
ELIAEAIHANSPRSKEAFVKVNLGGLSQSLFESEMFGHKKGAFTDAYMDRVGRFEMANKG
HHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEECCCC
TIFLDEIGDLELSCQVKLLRVLQDQTFEVLGDSRPRKVDIRVVSATNRDLRSMVADRTFR
EEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHH
EDLFYRINLITVHLPALRERREDIPLLARYFADKQSEINGLPRVEFSSDAQTYLSRLPFP
HHHHEEEEEEEEECHHHHHHHCCCHHHHHHHCCCHHHCCCCCCCEECCCHHHHHHHCCCC
GNIRELKNLVERTILVSGKTLLDTADFEVHCMNTSGAKSTIPPSLEGLTLDELEKQTILR
CCHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
SLEAHGGNLSHVATALGISRAALYRRLEKYGIPIDK
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MILIIDDDAAVRSSLTFLLKRAGFRPEAVPGPKEALEVVRATAPELILMDMNFTLTTTGE
CEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCEEEEECCH
EGIQLLRQVKIFRPDVPVILMTAWGSISLAVQGMQAGAFDFITKPWNNLVLLKSIRTALE
HHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHCCCCCEEHHHHHHHHHH
LSEQKKEANAPLNRSDADHKFHFDKIVGQSAALMDVLGTVSRIAPTNASVLITGESGTGK
HHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
ELIAEAIHANSPRSKEAFVKVNLGGLSQSLFESEMFGHKKGAFTDAYMDRVGRFEMANKG
HHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEECCCC
TIFLDEIGDLELSCQVKLLRVLQDQTFEVLGDSRPRKVDIRVVSATNRDLRSMVADRTFR
EEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHH
EDLFYRINLITVHLPALRERREDIPLLARYFADKQSEINGLPRVEFSSDAQTYLSRLPFP
HHHHEEEEEEEEECHHHHHHHCCCHHHHHHHCCCHHHCCCCCCCEECCCHHHHHHHCCCC
GNIRELKNLVERTILVSGKTLLDTADFEVHCMNTSGAKSTIPPSLEGLTLDELEKQTILR
CCHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
SLEAHGGNLSHVATALGISRAALYRRLEKYGIPIDK
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]