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The map label for this gene is obgE

Identifier: 150008511

GI number: 150008511

Start: 2253002

End: 2254162

Strand: Reverse

Name: obgE

Synonym: BDI_1897

Alternate gene names: 150008511

Gene position: 2254162-2253002 (Counterclockwise)

Preceding gene: 150008512

Following gene: 150008510

Centisome position: 46.85

GC content: 47.63

Gene sequence:

>1161_bases
ATGGCTGAATCGAACTTTGTAGATTATGTCAAGATCTATTGCCGCTCAGGAAAGGGTGGAAGAGGGTCTTCTCACTTCCG
TCGTGAGAAATACATTCCGAAAGGAGGTCCCGACGGGGGCGATGGAGGGAGAGGAGGTCATGTGTATCTCCGTGGTAACC
GGAATTACTGGACGCTCCTTCACTTGAAATATGAGCGTCATATCATGGCCACCAATGGTGAGAGTGGTAGCGCGAAGCGT
AGCTCGGGTAAAGACGGGGAGGATCGAGTAATCGAGGTTCCTTGCGGTACGGTTGTTTACGATGCTGAGACCGGAGAGTT
TATTTGCGACGTTACGGAAGACGGTCAGCAAGTGATGTTGCTGAAAGGCGGTCGTGGCGGTCTGGGGAATTTTAACTTCA
AGACGGCTACCAATCAAGCGCCCCGTTATTCGCAACCGGGTGAGCCGGCATTGGAACGTACGGTGATTCTTCAGTTGAAA
TTGCTGGCCGATGTCGGTTTGGTAGGCTTCCCGAATGCGGGTAAATCTACCTTGCTTTCTGTCGTATCCGCCGCTAAACC
GAAGATCGCTAATTATCCTTTTACTACGTTGGAGCCTAATTTAGGCATCGTGAGTTATCGCGATAACCGTTCGTTCGTAA
TGGCCGATATACCGGGTATTATCGAAGGAGCAAGCGAGGGAAAAGGTTTGGGACTTCGTTTCTTACGTCATATCGAACGT
AATTCATTGTTATTGTTCATGGTTCCCGCTGAGGCAGACGATATCAAGAAAGAATACGAGATATTGCATAATGAGTTAGT
GAAGTATAATCCGGAATTGCTGGATAAACGCCGTGTACTGGCGATCACCAAGAGCGATATGCTGGATGAGGAATTGATCG
AGGCTTTGTCGCAAGACTTGCCGGAGGGAATTCCGTATGTCTTTATATCTTCTATCACGGGACTGGGTATTGTCGAGTTG
AAAGACCTTTTATGGAAAGAGCTGAATAAGGAGAATTTCCATGAGGCAGAGCGAATTGTCCATAAGAATATAGATGTAAG
CACGTTGGAATTTGAGGACGACGACGAATACATCTTCCCCGTGGACGAGGACGAGGATGACCCGGATGAGGAATACGAGG
AATACTGGGACGATGATGAAGATGAAGATACAAGAAAATAA

Upstream 100 bases:

>100_bases
AGGCAAGCACGTGGCCATCAAAGGGATGGGAACAATCGAGGAAATCTTCGGTCGTATCAAAGAGGCGGTTAATAACGTAA
AATAATTGAAATAAACCAAT

Downstream 100 bases:

>100_bases
GCAAATAGAGGTGTCGCGGTTCTCCGGGTTAAGCGGATACCGCGACATTTCTCATTTTACGACAACACGTCATGGCGGCG
TGAGTACGGGAACGTACGCT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MAESNFVDYVKIYCRSGKGGRGSSHFRREKYIPKGGPDGGDGGRGGHVYLRGNRNYWTLLHLKYERHIMATNGESGSAKR
SSGKDGEDRVIEVPCGTVVYDAETGEFICDVTEDGQQVMLLKGGRGGLGNFNFKTATNQAPRYSQPGEPALERTVILQLK
LLADVGLVGFPNAGKSTLLSVVSAAKPKIANYPFTTLEPNLGIVSYRDNRSFVMADIPGIIEGASEGKGLGLRFLRHIER
NSLLLFMVPAEADDIKKEYEILHNELVKYNPELLDKRRVLAITKSDMLDEELIEALSQDLPEGIPYVFISSITGLGIVEL
KDLLWKELNKENFHEAERIVHKNIDVSTLEFEDDDEYIFPVDEDEDDPDEEYEEYWDDDEDEDTRK

Sequences:

>Translated_386_residues
MAESNFVDYVKIYCRSGKGGRGSSHFRREKYIPKGGPDGGDGGRGGHVYLRGNRNYWTLLHLKYERHIMATNGESGSAKR
SSGKDGEDRVIEVPCGTVVYDAETGEFICDVTEDGQQVMLLKGGRGGLGNFNFKTATNQAPRYSQPGEPALERTVILQLK
LLADVGLVGFPNAGKSTLLSVVSAAKPKIANYPFTTLEPNLGIVSYRDNRSFVMADIPGIIEGASEGKGLGLRFLRHIER
NSLLLFMVPAEADDIKKEYEILHNELVKYNPELLDKRRVLAITKSDMLDEELIEALSQDLPEGIPYVFISSITGLGIVEL
KDLLWKELNKENFHEAERIVHKNIDVSTLEFEDDDEYIFPVDEDEDDPDEEYEEYWDDDEDEDTRK
>Mature_385_residues
AESNFVDYVKIYCRSGKGGRGSSHFRREKYIPKGGPDGGDGGRGGHVYLRGNRNYWTLLHLKYERHIMATNGESGSAKRS
SGKDGEDRVIEVPCGTVVYDAETGEFICDVTEDGQQVMLLKGGRGGLGNFNFKTATNQAPRYSQPGEPALERTVILQLKL
LADVGLVGFPNAGKSTLLSVVSAAKPKIANYPFTTLEPNLGIVSYRDNRSFVMADIPGIIEGASEGKGLGLRFLRHIERN
SLLLFMVPAEADDIKKEYEILHNELVKYNPELLDKRRVLAITKSDMLDEELIEALSQDLPEGIPYVFISSITGLGIVELK
DLLWKELNKENFHEAERIVHKNIDVSTLEFEDDDEYIFPVDEDEDDPDEEYEEYWDDDEDEDTRK

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI111955139, Length=372, Percent_Identity=35.4838709677419, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI24308117, Length=335, Percent_Identity=39.1044776119403, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI111955063, Length=289, Percent_Identity=33.5640138408304, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4557537, Length=119, Percent_Identity=34.453781512605, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4758796, Length=86, Percent_Identity=40.6976744186046, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=32.3529411764706, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=47.8658536585366, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI1787454, Length=90, Percent_Identity=40, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=330, Percent_Identity=37.2727272727273, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=306, Percent_Identity=29.4117647058824, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71981008, Length=121, Percent_Identity=38.0165289256198, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=137, Percent_Identity=32.1167883211679, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=110, Percent_Identity=37.2727272727273, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=172, Percent_Identity=40.6976744186046, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319281, Length=123, Percent_Identity=38.2113821138211, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=121, Percent_Identity=34.7107438016529, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585318, Length=231, Percent_Identity=45.8874458874459, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129375, Length=220, Percent_Identity=40.9090909090909, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI21356473, Length=104, Percent_Identity=39.4230769230769, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17981711, Length=86, Percent_Identity=46.5116279069767, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PARD8 (A6LD68)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303254.1
- STRING:   A6LD68
- GeneID:   5307047
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_1897
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12298
- BioCyc:   PDIS435591:BDI_1897-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 43307; Mature: 43176

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESNFVDYVKIYCRSGKGGRGSSHFRREKYIPKGGPDGGDGGRGGHVYLRGNRNYWTLL
CCCCCHHHEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEE
HLKYERHIMATNGESGSAKRSSGKDGEDRVIEVPCGTVVYDAETGEFICDVTEDGQQVML
EEEEECEEEEECCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCCEEEEECCCCCEEEE
LKGGRGGLGNFNFKTATNQAPRYSQPGEPALERTVILQLKLLADVGLVGFPNAGKSTLLS
EECCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHEEEHHHHCCCEECCCCCHHHHHH
VVSAAKPKIANYPFTTLEPNLGIVSYRDNRSFVMADIPGIIEGASEGKGLGLRFLRHIER
HHHHCCCCCCCCCCCEECCCCCEEEEECCCEEEEEECCHHHCCCCCCCCHHHHHHHHHCC
NSLLLFMVPAEADDIKKEYEILHNELVKYNPELLDKRRVLAITKSDMLDEELIEALSQDL
CCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECHHHHHHHHHHHHHHHC
PEGIPYVFISSITGLGIVELKDLLWKELNKENFHEAERIVHKNIDVSTLEFEDDDEYIFP
CCCCCEEEEHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEE
VDEDEDDPDEEYEEYWDDDEDEDTRK
CCCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AESNFVDYVKIYCRSGKGGRGSSHFRREKYIPKGGPDGGDGGRGGHVYLRGNRNYWTLL
CCCCHHHEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEE
HLKYERHIMATNGESGSAKRSSGKDGEDRVIEVPCGTVVYDAETGEFICDVTEDGQQVML
EEEEECEEEEECCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCCEEEEECCCCCEEEE
LKGGRGGLGNFNFKTATNQAPRYSQPGEPALERTVILQLKLLADVGLVGFPNAGKSTLLS
EECCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHEEEHHHHCCCEECCCCCHHHHHH
VVSAAKPKIANYPFTTLEPNLGIVSYRDNRSFVMADIPGIIEGASEGKGLGLRFLRHIER
HHHHCCCCCCCCCCCEECCCCCEEEEECCCEEEEEECCHHHCCCCCCCCHHHHHHHHHCC
NSLLLFMVPAEADDIKKEYEILHNELVKYNPELLDKRRVLAITKSDMLDEELIEALSQDL
CCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECHHHHHHHHHHHHHHHC
PEGIPYVFISSITGLGIVELKDLLWKELNKENFHEAERIVHKNIDVSTLEFEDDDEYIFP
CCCCCEEEEHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEE
VDEDEDDPDEEYEEYWDDDEDEDTRK
CCCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA