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The map label for this gene is maeB [H]

Identifier: 150008359

GI number: 150008359

Start: 2051646

End: 2053934

Strand: Direct

Name: maeB [H]

Synonym: BDI_1733

Alternate gene names: 150008359

Gene position: 2051646-2053934 (Clockwise)

Preceding gene: 150008354

Following gene: 150008362

Centisome position: 42.64

GC content: 56.09

Gene sequence:

>2289_bases
ATGGCAAAGATTACAAAAGAGGAGGCCCTTCGGTACCATGCCGAGGGCAAACCGGGTAAGATCGAGGTTATCCCGACAAA
GCCTCATAGCACGCAAACGGATTTATCCCTGGCTTATTCGCCGGGCGTAGCCGAGCCGTGTCTGGAAATCGAGAAGAATC
CGCTGGACGCGTACGAATATACGGCGAAAGGTAATTTGGTAGCCGTAATCTCCAACGGTACCGCCGTACTCGGGCTGGGC
GATATCGGTCCCTTGGCCGGTAAGCCGGTGATGGAAGGCAAGGGATTGCTATTCAAGATATTCGCGGGTATCGACGTATT
CGATATCGAGGTGAACGAGAAAGATCCGGAGAAGTTTATCCAGACCGTGAAGGCGATCTCGCCCACGTTCGGAGGAATCA
ACTTGGAGGATATCAAGGCACCGGAGTGTTTCGAGATCGAGACTCGCCTGAAGAACGAGCTGGATATCCCCGTCATGCAC
GACGACCAGCATGGTACGGCAATCATCTCCGGCGCCGGGCTGATCAACGCCTTGGAGATCGCCGGCAAGAAGATCGAGGA
CGTGAAGATCGTGGTGAACGGCGCCGGAGCCGCCTCTATCTCATGTACGAGACTGTACGTGATGCTGGGAGCGCGCAAGG
AGAATATCGTCATGTGCGACAGCAAGGGCGTTATCTCTACCAGTCGCCCGGACTTGAACGCCGCCAAGCGGGAGTTCGCT
ACCGACCGCCCGATCAAGACCTTGCAAGAGGCCGTGGTGGGAGCCGACGTATTCTTGGGCCTCTCCGTGGCGAACGTATT
GACCAAGGAGATGGTACGTAGCATGAACGCCGACCCGATCGTATTCGCCTTGGCGAACCCGAACCCGGAGATCTCCTACG
CCGACGCTATGGCCTCGCGGGACGATATCATCTTCGCTACCGGACGTTCCGACTATCCGAACCAGATCAACAACGTGCTG
GGATTCCCTTATATCTTCCGCGGCGCCTTGGACACGCACGCCAAGGCGATCAACGAGGAGATGAAGCTGGCCGCCGTCTA
CGCTATCGCCGACCTTGCCAAGGAACCGGTTCCCGACGTGGTGAACGCCGCCTATAAGCTGAAACGAACCACTTTCGGAC
GCGACTATATCCTTCCGAAAGCGCTCGATCCCCGTTTGCTGACCCGTGTATCTTGCGCCGTGGCGAAAGCCGCTATCGAC
TCGGGCGTGTCTCGCAAGACGATCACCGACTGGGAGGGCTACGCCAACCATTTGCGTGAGATGATGGGGTACGATAATAA
ACTCTTGCGCTCGTTCACCGATATGGCGAAAGCGAACCCGAAACGGGTGGTATTCGCCGAGGCGAACCACGTGAATATGC
TGAAAGCCGCCGCCGAGGCGAAAGCGGAAGGTATCTGTTTCCCGATCTTGCTGGGTAACGAGGAGCGTCTGGCCAAGATC
GCCGCCGAGGAGAATATCAGTCTGGACGGTATCGAGATCGTCAACCTCCGCCACGACCGTGAGACGGAACGCCGCCACCG
CTACGCCCGTATCCTTACCGACAAGAAGGCGCGCGAGGGCGTGACCTACTCGGAGGCTTGCGAGAAAATGGTAGACCGTA
ACGCCTTTGGTATGATGATGGTGGCTACCGGCGACGCTGACGCTTTCGTGACGGGTGTATACAGCCGCTACTCGGAGGTT
ACAAAGATGGCGGAACAGATCATCGGCATCCGCCCGAGCTACAAGCATTTCGGCGCCTTGAACATCTTGACTTGTAAGAA
GGGTACGTTCTTTATGGCCGATACGCTGATCAACCGCCACCCGTCGGCCGAGGTATTGATCGATATCGCCCGCCTGACGC
ACGACGCCGTGAAGTTCTTCGCTCACGAGCCGGTTATGGCGATGTTGTCTTACTCGAACTTCGGTTCCGACAAGCAGGGC
AGTCCGCTGAAAGTACACGAGGCGATCGACTTCTTGCATAAGACATACCCAGACATGGTAGTAGACGGAGAGATGCAAGT
AAACTTCGCCCTCGACAAGAAGCTGCGCGACGATATGTATCCGTTCAACAAGCTGAAAGGGCAAGACGTGAATACCTTGA
TCTTCCCGAACCTAAGCTCCGCCAACAGCGCGTACAAGCTATTGGATACGCTGGGTATCACCGAGACGATCGGCCCGATC
CAGATGGGATTGAACAAACCGATCCACTTCACCGACGTAGAAAGCTCTACCCGTGATATCGTGAACCTGACGACCGTAGC
TGTCGTAGACGCTATCGTTCAGGAGCAGATCGAGAAAGAAAACAGATAA

Upstream 100 bases:

>100_bases
CTTGAAAAAACTATTTGTAAGCAAAACCTAGTAAACTCATAATAATTTGTTACTTTTGCGGTGGTTTTAAATAGGAACAA
CATAATTAATAAACATACCT

Downstream 100 bases:

>100_bases
GTTTTGATGCGGATGACGCAGATAACACGGATAAGAATAAAATAAATCCGTGTCATCCGTGTCATCTGCGTCATCTGCGT
CTAAAAGATAGACCACCAAG

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MAKITKEEALRYHAEGKPGKIEVIPTKPHSTQTDLSLAYSPGVAEPCLEIEKNPLDAYEYTAKGNLVAVISNGTAVLGLG
DIGPLAGKPVMEGKGLLFKIFAGIDVFDIEVNEKDPEKFIQTVKAISPTFGGINLEDIKAPECFEIETRLKNELDIPVMH
DDQHGTAIISGAGLINALEIAGKKIEDVKIVVNGAGAASISCTRLYVMLGARKENIVMCDSKGVISTSRPDLNAAKREFA
TDRPIKTLQEAVVGADVFLGLSVANVLTKEMVRSMNADPIVFALANPNPEISYADAMASRDDIIFATGRSDYPNQINNVL
GFPYIFRGALDTHAKAINEEMKLAAVYAIADLAKEPVPDVVNAAYKLKRTTFGRDYILPKALDPRLLTRVSCAVAKAAID
SGVSRKTITDWEGYANHLREMMGYDNKLLRSFTDMAKANPKRVVFAEANHVNMLKAAAEAKAEGICFPILLGNEERLAKI
AAEENISLDGIEIVNLRHDRETERRHRYARILTDKKAREGVTYSEACEKMVDRNAFGMMMVATGDADAFVTGVYSRYSEV
TKMAEQIIGIRPSYKHFGALNILTCKKGTFFMADTLINRHPSAEVLIDIARLTHDAVKFFAHEPVMAMLSYSNFGSDKQG
SPLKVHEAIDFLHKTYPDMVVDGEMQVNFALDKKLRDDMYPFNKLKGQDVNTLIFPNLSSANSAYKLLDTLGITETIGPI
QMGLNKPIHFTDVESSTRDIVNLTTVAVVDAIVQEQIEKENR

Sequences:

>Translated_762_residues
MAKITKEEALRYHAEGKPGKIEVIPTKPHSTQTDLSLAYSPGVAEPCLEIEKNPLDAYEYTAKGNLVAVISNGTAVLGLG
DIGPLAGKPVMEGKGLLFKIFAGIDVFDIEVNEKDPEKFIQTVKAISPTFGGINLEDIKAPECFEIETRLKNELDIPVMH
DDQHGTAIISGAGLINALEIAGKKIEDVKIVVNGAGAASISCTRLYVMLGARKENIVMCDSKGVISTSRPDLNAAKREFA
TDRPIKTLQEAVVGADVFLGLSVANVLTKEMVRSMNADPIVFALANPNPEISYADAMASRDDIIFATGRSDYPNQINNVL
GFPYIFRGALDTHAKAINEEMKLAAVYAIADLAKEPVPDVVNAAYKLKRTTFGRDYILPKALDPRLLTRVSCAVAKAAID
SGVSRKTITDWEGYANHLREMMGYDNKLLRSFTDMAKANPKRVVFAEANHVNMLKAAAEAKAEGICFPILLGNEERLAKI
AAEENISLDGIEIVNLRHDRETERRHRYARILTDKKAREGVTYSEACEKMVDRNAFGMMMVATGDADAFVTGVYSRYSEV
TKMAEQIIGIRPSYKHFGALNILTCKKGTFFMADTLINRHPSAEVLIDIARLTHDAVKFFAHEPVMAMLSYSNFGSDKQG
SPLKVHEAIDFLHKTYPDMVVDGEMQVNFALDKKLRDDMYPFNKLKGQDVNTLIFPNLSSANSAYKLLDTLGITETIGPI
QMGLNKPIHFTDVESSTRDIVNLTTVAVVDAIVQEQIEKENR
>Mature_761_residues
AKITKEEALRYHAEGKPGKIEVIPTKPHSTQTDLSLAYSPGVAEPCLEIEKNPLDAYEYTAKGNLVAVISNGTAVLGLGD
IGPLAGKPVMEGKGLLFKIFAGIDVFDIEVNEKDPEKFIQTVKAISPTFGGINLEDIKAPECFEIETRLKNELDIPVMHD
DQHGTAIISGAGLINALEIAGKKIEDVKIVVNGAGAASISCTRLYVMLGARKENIVMCDSKGVISTSRPDLNAAKREFAT
DRPIKTLQEAVVGADVFLGLSVANVLTKEMVRSMNADPIVFALANPNPEISYADAMASRDDIIFATGRSDYPNQINNVLG
FPYIFRGALDTHAKAINEEMKLAAVYAIADLAKEPVPDVVNAAYKLKRTTFGRDYILPKALDPRLLTRVSCAVAKAAIDS
GVSRKTITDWEGYANHLREMMGYDNKLLRSFTDMAKANPKRVVFAEANHVNMLKAAAEAKAEGICFPILLGNEERLAKIA
AEENISLDGIEIVNLRHDRETERRHRYARILTDKKAREGVTYSEACEKMVDRNAFGMMMVATGDADAFVTGVYSRYSEVT
KMAEQIIGIRPSYKHFGALNILTCKKGTFFMADTLINRHPSAEVLIDIARLTHDAVKFFAHEPVMAMLSYSNFGSDKQGS
PLKVHEAIDFLHKTYPDMVVDGEMQVNFALDKKLRDDMYPFNKLKGQDVNTLIFPNLSSANSAYKLLDTLGITETIGPIQ
MGLNKPIHFTDVESSTRDIVNLTTVAVVDAIVQEQIEKENR

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI62420882, Length=353, Percent_Identity=28.0453257790368, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI62420880, Length=353, Percent_Identity=28.0453257790368, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI239049447, Length=353, Percent_Identity=28.0453257790368, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI4505143, Length=344, Percent_Identity=27.0348837209302, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1788806, Length=760, Percent_Identity=49.0789473684211, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=335, Percent_Identity=29.8507462686567, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI1788635, Length=326, Percent_Identity=28.2208588957055, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI87081919, Length=409, Percent_Identity=27.1393643031785, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17537199, Length=412, Percent_Identity=27.1844660194175, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646386, Length=390, Percent_Identity=28.7179487179487, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646388, Length=390, Percent_Identity=28.7179487179487, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281362674, Length=398, Percent_Identity=27.8894472361809, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281362672, Length=398, Percent_Identity=27.8894472361809, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21356279, Length=398, Percent_Identity=27.8894472361809, Blast_Score=93, Evalue=7e-19,
Organism=Drosophila melanogaster, GI78707242, Length=428, Percent_Identity=24.5327102803738, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI78707238, Length=428, Percent_Identity=24.5327102803738, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI78707240, Length=398, Percent_Identity=25.3768844221106, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 83729; Mature: 83598

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKITKEEALRYHAEGKPGKIEVIPTKPHSTQTDLSLAYSPGVAEPCLEIEKNPLDAYEY
CCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCEEE
TAKGNLVAVISNGTAVLGLGDIGPLAGKPVMEGKGLLFKIFAGIDVFDIEVNEKDPEKFI
ECCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHH
QTVKAISPTFGGINLEDIKAPECFEIETRLKNELDIPVMHDDQHGTAIISGAGLINALEI
HHHHHHCCCCCCCCHHHCCCCCCEEHHHHHCCCCCCCEEECCCCCCEEEECCCHHHHHHH
AGKKIEDVKIVVNGAGAASISCTRLYVMLGARKENIVMCDSKGVISTSRPDLNAAKREFA
CCCCCCEEEEEEECCCCCCCHHEEEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHC
TDRPIKTLQEAVVGADVFLGLSVANVLTKEMVRSMNADPIVFALANPNPEISYADAMASR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCC
DDIIFATGRSDYPNQINNVLGFPYIFRGALDTHAKAINEEMKLAAVYAIADLAKEPVPDV
CCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VNAAYKLKRTTFGRDYILPKALDPRLLTRVSCAVAKAAIDSGVSRKTITDWEGYANHLRE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
MMGYDNKLLRSFTDMAKANPKRVVFAEANHVNMLKAAAEAKAEGICFPILLGNEERLAKI
HHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHH
AAEENISLDGIEIVNLRHDRETERRHRYARILTDKKAREGVTYSEACEKMVDRNAFGMMM
HHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCCCCCEEEE
VATGDADAFVTGVYSRYSEVTKMAEQIIGIRPSYKHFGALNILTCKKGTFFMADTLINRH
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCEEEHHHHHCCC
PSAEVLIDIARLTHDAVKFFAHEPVMAMLSYSNFGSDKQGSPLKVHEAIDFLHKTYPDMV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHCCCCEE
VDGEMQVNFALDKKLRDDMYPFNKLKGQDVNTLIFPNLSSANSAYKLLDTLGITETIGPI
ECCCEEEEEEECHHHHHCCCCHHHCCCCCCCEEEECCCCCCCHHHHHHHHHCCHHCCCHH
QMGLNKPIHFTDVESSTRDIVNLTTVAVVDAIVQEQIEKENR
HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKITKEEALRYHAEGKPGKIEVIPTKPHSTQTDLSLAYSPGVAEPCLEIEKNPLDAYEY
CCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCEEE
TAKGNLVAVISNGTAVLGLGDIGPLAGKPVMEGKGLLFKIFAGIDVFDIEVNEKDPEKFI
ECCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHH
QTVKAISPTFGGINLEDIKAPECFEIETRLKNELDIPVMHDDQHGTAIISGAGLINALEI
HHHHHHCCCCCCCCHHHCCCCCCEEHHHHHCCCCCCCEEECCCCCCEEEECCCHHHHHHH
AGKKIEDVKIVVNGAGAASISCTRLYVMLGARKENIVMCDSKGVISTSRPDLNAAKREFA
CCCCCCEEEEEEECCCCCCCHHEEEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHC
TDRPIKTLQEAVVGADVFLGLSVANVLTKEMVRSMNADPIVFALANPNPEISYADAMASR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCC
DDIIFATGRSDYPNQINNVLGFPYIFRGALDTHAKAINEEMKLAAVYAIADLAKEPVPDV
CCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VNAAYKLKRTTFGRDYILPKALDPRLLTRVSCAVAKAAIDSGVSRKTITDWEGYANHLRE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
MMGYDNKLLRSFTDMAKANPKRVVFAEANHVNMLKAAAEAKAEGICFPILLGNEERLAKI
HHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHH
AAEENISLDGIEIVNLRHDRETERRHRYARILTDKKAREGVTYSEACEKMVDRNAFGMMM
HHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCCCCCEEEE
VATGDADAFVTGVYSRYSEVTKMAEQIIGIRPSYKHFGALNILTCKKGTFFMADTLINRH
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCEEEHHHHHCCC
PSAEVLIDIARLTHDAVKFFAHEPVMAMLSYSNFGSDKQGSPLKVHEAIDFLHKTYPDMV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHCCCCEE
VDGEMQVNFALDKKLRDDMYPFNKLKGQDVNTLIFPNLSSANSAYKLLDTLGITETIGPI
ECCCEEEEEEECHHHHHCCCCHHHCCCCCCCEEEECCCCCCCHHHHHHHHHCCHHCCCHH
QMGLNKPIHFTDVESSTRDIVNLTTVAVVDAIVQEQIEKENR
HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]