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The map label for this gene is trxA [H]

Identifier: 150008339

GI number: 150008339

Start: 2027403

End: 2027876

Strand: Reverse

Name: trxA [H]

Synonym: BDI_1711

Alternate gene names: 150008339

Gene position: 2027876-2027403 (Counterclockwise)

Preceding gene: 150008340

Following gene: 150008338

Centisome position: 42.15

GC content: 42.62

Gene sequence:

>474_bases
ATGAGAAAGTTGAAAAGTTTATGGCTGGTTTCGGTTGTGCTGCTATTAGTAAGCTGCTCGATGTCCGCTAAATCAGATAA
ATCAAGTGAGGCTGGTACCGCCTCCAAGGGAGAGGTCGTTACTTTGAACAAGGCAGAGTTCTTGCAAAAGGTATTCAATT
ACGAGAAGAACGCAACGAAATGGGTATATGAAGGTGATAAGCCTTGTATCATCGATTTTTATGCGGACTGGTGTGGTCCC
TGCAAGCAAGTGGCTCCTATTTTAAGGGATTTGGCTATCCTGTATAAGAATGATATCGTAGTTTATAAGGTAAATGTGGA
TAAGGAAAAGGAGTTGGCTGCCGCTTTCGGCATACAAAGTATTCCTACGTTCTTGTTTATCCCTAAGGAAGGACAGCCTC
AGATATCGATGGGAGCTCTTCCCCGTGAGGAGTTTGTGAAACAGATCGATACTTTCTTGTTGAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
TTTGTTTATTCTTTTCTTTTAAGAATAGAATGTGTGGGAATCCCCTTTTTATTGCTATTTTTGTAGCAAATAATTTATCA
ATCAAGTAAAAGGTTTCTAT

Downstream 100 bases:

>100_bases
CACGACTTAGTTAATCATCATTTATAGATCGGAAAGCCGTAGAATTTTAGATTTTACGGCTTTTTTAATTGGGAGGGATG
CTTTATGAAAGTAGGAATTA

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRKLKSLWLVSVVLLLVSCSMSAKSDKSSEAGTASKGEVVTLNKAEFLQKVFNYEKNATKWVYEGDKPCIIDFYADWCGP
CKQVAPILRDLAILYKNDIVVYKVNVDKEKELAAAFGIQSIPTFLFIPKEGQPQISMGALPREEFVKQIDTFLLKKK

Sequences:

>Translated_157_residues
MRKLKSLWLVSVVLLLVSCSMSAKSDKSSEAGTASKGEVVTLNKAEFLQKVFNYEKNATKWVYEGDKPCIIDFYADWCGP
CKQVAPILRDLAILYKNDIVVYKVNVDKEKELAAAFGIQSIPTFLFIPKEGQPQISMGALPREEFVKQIDTFLLKKK
>Mature_157_residues
MRKLKSLWLVSVVLLLVSCSMSAKSDKSSEAGTASKGEVVTLNKAEFLQKVFNYEKNATKWVYEGDKPCIIDFYADWCGP
CKQVAPILRDLAILYKNDIVVYKVNVDKEKELAAAFGIQSIPTFLFIPKEGQPQISMGALPREEFVKQIDTFLLKKK

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=100, Percent_Identity=40, Blast_Score=74, Evalue=4e-15,
Organism=Escherichia coli, GI87082331, Length=92, Percent_Identity=35.8695652173913, Blast_Score=72, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71980562, Length=86, Percent_Identity=34.8837209302326, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71980565, Length=57, Percent_Identity=45.6140350877193, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212646193, Length=95, Percent_Identity=33.6842105263158, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=77, Percent_Identity=37.6623376623377, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639826, Length=62, Percent_Identity=53.2258064516129, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17530795, Length=74, Percent_Identity=40.5405405405405, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17648013, Length=61, Percent_Identity=42.6229508196721, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583090, Length=61, Percent_Identity=42.6229508196721, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 17685; Mature: 17685

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLKSLWLVSVVLLLVSCSMSAKSDKSSEAGTASKGEVVTLNKAEFLQKVFNYEKNATK
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCCCE
WVYEGDKPCIIDFYADWCGPCKQVAPILRDLAILYKNDIVVYKVNVDKEKELAAAFGIQS
EEEECCCCEEEEECHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCHHH
IPTFLFIPKEGQPQISMGALPREEFVKQIDTFLLKKK
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKLKSLWLVSVVLLLVSCSMSAKSDKSSEAGTASKGEVVTLNKAEFLQKVFNYEKNATK
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCCCE
WVYEGDKPCIIDFYADWCGPCKQVAPILRDLAILYKNDIVVYKVNVDKEKELAAAFGIQS
EEEECCCCEEEEECHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCHHH
IPTFLFIPKEGQPQISMGALPREEFVKQIDTFLLKKK
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]