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The map label for this gene is mntH [H]

Identifier: 150008024

GI number: 150008024

Start: 1609360

End: 1610613

Strand: Direct

Name: mntH [H]

Synonym: BDI_1387

Alternate gene names: 150008024

Gene position: 1609360-1610613 (Clockwise)

Preceding gene: 150008023

Following gene: 150008025

Centisome position: 33.45

GC content: 56.06

Gene sequence:

>1254_bases
ATGAACTTACTAGACAAACTGAAGATCAACCACCGCCCCCGCTCCGGGGCATTGGATTTGCTAAAATATATCGGCCCCGG
ATTACTTGTCACCGTAGGCTTTATCGATCCCGGAAACTGGGCGACGAATCTCGCGGCAGGCTCCGAGTTCGGCTACGCCC
TCCTGTGGGTCGTCACCTTCTCGTCCGTCATGCTGATCATTATCCAGCACAACGTGGCCCACCTCGGTATCGTGACCGGC
CTCTGCCTCTCGGAGGCGACCAACAAATACATGCCGCGCGTGCTAAGCCGCCCGATCCTAGGATCGGCCATGCTCGCCAG
CGTATCCACCTCCCTCGCCGAGATACTCGGTGGAGCCATCGCCCTCCGGATGCTGTTCGGTATGCCGATCAAGGCGGGAG
CGGTGATCGTCACCATCGTATGCCTCGCCATGCTATTCAGTAATACATACAGCAAGACCGAACGCTGGATCATCACGTTC
GTGTCCATTATCGGGCTCTCGTTCCTATACGAGCTGGCGTTGGTCGACGTAGACTGGGGGCAGGCCGTGGTAGGCTGGGT
GAAACCCACCTTCCCCGAGAACTCCATGCTGATCATCATGAGCGTACTGGGAGCCGTCGTGATGCCTCACAACCTGTTCC
TGCACTCGGAGGTGATACAGAGCCGGGAATGGAACCTAGAGGACGAGTCGGTCATCAAGAAACAACTGAAGTACGAGTTC
TACGACACGCTCCTGTCCATGGTGATCGGCTGGGCGATCAACTCGGCGATGATCATCTTGGCCGCCTCTACCTTCTTCAA
GCAAAACATCGCCGTAGACGAGCTGGACCAAGCGCAACAGTTATTGGTACCCCTCGTAGGAAACAACGCCGGGGTGATTT
TCGCCGCCGCCCTATTACTGGCGGGTATCTCCTCGACCATCACATCCGGTATCGCCGGGGCTTCCATCTTCGCCGGATTC
TATGGCGAGGCGTACAATCATACCGACCTCCACTCAAAGCTGGGAGTCCTGCTATCGTTCGTCCCCGCCTTGGCCATCAT
ATTCCTGATCGGCGATCCGTTCAAGGGATTGATCCTGTCGCAGATGTTGTTGAGCGTGCAATTGCCGATCACGGTCTTCA
CGCAAGTGTACCTCACTTCCAGCAAGAAGGTCATGGGTGTCTACGCGAACAGCCGCTCTACGACCATCATCCTCTTGCTG
TTGGGAACGATGGTAACCGTCCTAAATATAGCCCTGCTCATCAGCCTATTTTAA

Upstream 100 bases:

>100_bases
CGCCATCGGCCGTACGAACGTATTTCCGGCCACCGTTGGGTAACAACGAAACTATTCGTATCTTTACGCTGTTTTTTAAT
TTAAAAGTATCTATACAAAC

Downstream 100 bases:

>100_bases
AAAGAAATCGCTACCTTTGCCCCATTCGAAGAAAAACTATCAATTTTTAAGTATGAGCGATATCAATACAAACGAAGAAG
AAGGCAAGAAGAACCTGAAT

Product: Mn2+ and Fe2+ transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNLLDKLKINHRPRSGALDLLKYIGPGLLVTVGFIDPGNWATNLAAGSEFGYALLWVVTFSSVMLIIIQHNVAHLGIVTG
LCLSEATNKYMPRVLSRPILGSAMLASVSTSLAEILGGAIALRMLFGMPIKAGAVIVTIVCLAMLFSNTYSKTERWIITF
VSIIGLSFLYELALVDVDWGQAVVGWVKPTFPENSMLIIMSVLGAVVMPHNLFLHSEVIQSREWNLEDESVIKKQLKYEF
YDTLLSMVIGWAINSAMIILAASTFFKQNIAVDELDQAQQLLVPLVGNNAGVIFAAALLLAGISSTITSGIAGASIFAGF
YGEAYNHTDLHSKLGVLLSFVPALAIIFLIGDPFKGLILSQMLLSVQLPITVFTQVYLTSSKKVMGVYANSRSTTIILLL
LGTMVTVLNIALLISLF

Sequences:

>Translated_417_residues
MNLLDKLKINHRPRSGALDLLKYIGPGLLVTVGFIDPGNWATNLAAGSEFGYALLWVVTFSSVMLIIIQHNVAHLGIVTG
LCLSEATNKYMPRVLSRPILGSAMLASVSTSLAEILGGAIALRMLFGMPIKAGAVIVTIVCLAMLFSNTYSKTERWIITF
VSIIGLSFLYELALVDVDWGQAVVGWVKPTFPENSMLIIMSVLGAVVMPHNLFLHSEVIQSREWNLEDESVIKKQLKYEF
YDTLLSMVIGWAINSAMIILAASTFFKQNIAVDELDQAQQLLVPLVGNNAGVIFAAALLLAGISSTITSGIAGASIFAGF
YGEAYNHTDLHSKLGVLLSFVPALAIIFLIGDPFKGLILSQMLLSVQLPITVFTQVYLTSSKKVMGVYANSRSTTIILLL
LGTMVTVLNIALLISLF
>Mature_417_residues
MNLLDKLKINHRPRSGALDLLKYIGPGLLVTVGFIDPGNWATNLAAGSEFGYALLWVVTFSSVMLIIIQHNVAHLGIVTG
LCLSEATNKYMPRVLSRPILGSAMLASVSTSLAEILGGAIALRMLFGMPIKAGAVIVTIVCLAMLFSNTYSKTERWIITF
VSIIGLSFLYELALVDVDWGQAVVGWVKPTFPENSMLIIMSVLGAVVMPHNLFLHSEVIQSREWNLEDESVIKKQLKYEF
YDTLLSMVIGWAINSAMIILAASTFFKQNIAVDELDQAQQLLVPLVGNNAGVIFAAALLLAGISSTITSGIAGASIFAGF
YGEAYNHTDLHSKLGVLLSFVPALAIIFLIGDPFKGLILSQMLLSVQLPITVFTQVYLTSSKKVMGVYANSRSTTIILLL
LGTMVTVLNIALLISLF

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=343, Percent_Identity=28.8629737609329, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI295293171, Length=405, Percent_Identity=27.1604938271605, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI295293169, Length=405, Percent_Identity=27.1604938271605, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI295293175, Length=406, Percent_Identity=27.0935960591133, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI295293173, Length=406, Percent_Identity=27.0935960591133, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI10835169, Length=406, Percent_Identity=27.0935960591133, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI295293178, Length=406, Percent_Identity=27.0935960591133, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI295293167, Length=406, Percent_Identity=27.0935960591133, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1788736, Length=400, Percent_Identity=32.25, Blast_Score=172, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17569473, Length=379, Percent_Identity=27.7044854881267, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71999499, Length=441, Percent_Identity=24.9433106575964, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193210616, Length=435, Percent_Identity=25.9770114942529, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71993856, Length=209, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323062, Length=398, Percent_Identity=31.6582914572864, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324450, Length=416, Percent_Identity=30.0480769230769, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6321841, Length=415, Percent_Identity=29.1566265060241, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24648607, Length=438, Percent_Identity=26.9406392694064, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281362176, Length=438, Percent_Identity=26.9406392694064, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24648609, Length=438, Percent_Identity=26.9406392694064, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI45553443, Length=414, Percent_Identity=27.2946859903382, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 45131; Mature: 45131

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLDKLKINHRPRSGALDLLKYIGPGLLVTVGFIDPGNWATNLAAGSEFGYALLWVVTF
CCCHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHCCCCCCHHHHHHHHHHH
SSVMLIIIQHNVAHLGIVTGLCLSEATNKYMPRVLSRPILGSAMLASVSTSLAEILGGAI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ALRMLFGMPIKAGAVIVTIVCLAMLFSNTYSKTERWIITFVSIIGLSFLYELALVDVDWG
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
QAVVGWVKPTFPENSMLIIMSVLGAVVMPHNLFLHSEVIQSREWNLEDESVIKKQLKYEF
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
YDTLLSMVIGWAINSAMIILAASTFFKQNIAVDELDQAQQLLVPLVGNNAGVIFAAALLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AGISSTITSGIAGASIFAGFYGEAYNHTDLHSKLGVLLSFVPALAIIFLIGDPFKGLILS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QMLLSVQLPITVFTQVYLTSSKKVMGVYANSRSTTIILLLLGTMVTVLNIALLISLF
HHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLLDKLKINHRPRSGALDLLKYIGPGLLVTVGFIDPGNWATNLAAGSEFGYALLWVVTF
CCCHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHCCCCCCHHHHHHHHHHH
SSVMLIIIQHNVAHLGIVTGLCLSEATNKYMPRVLSRPILGSAMLASVSTSLAEILGGAI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ALRMLFGMPIKAGAVIVTIVCLAMLFSNTYSKTERWIITFVSIIGLSFLYELALVDVDWG
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
QAVVGWVKPTFPENSMLIIMSVLGAVVMPHNLFLHSEVIQSREWNLEDESVIKKQLKYEF
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
YDTLLSMVIGWAINSAMIILAASTFFKQNIAVDELDQAQQLLVPLVGNNAGVIFAAALLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AGISSTITSGIAGASIFAGFYGEAYNHTDLHSKLGVLLSFVPALAIIFLIGDPFKGLILS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QMLLSVQLPITVFTQVYLTSSKKVMGVYANSRSTTIILLLLGTMVTVLNIALLISLF
HHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]