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The map label for this gene is sasA [H]

Identifier: 150007937

GI number: 150007937

Start: 1508002

End: 1509126

Strand: Direct

Name: sasA [H]

Synonym: BDI_1298

Alternate gene names: 150007937

Gene position: 1508002-1509126 (Clockwise)

Preceding gene: 150007936

Following gene: 150007938

Centisome position: 31.34

GC content: 49.51

Gene sequence:

>1125_bases
ATGGATAAATTGGCCTCAGAGTATAAAGTTCTTATCGTAGATGATGTCCCTACAAACGTCATGCTAGTACAAGCCATACT
GAAGAAAGAGGGATATACGCTTTTGACTTGCGACAGCGGGACAAAAGCACTACGCATAGCTAACGAGAAACACCCAAATC
TGATATTACTCGATATCATGATGCCTGAGATGGACGGATATGAGGTCCTCCAGCATCTGAAAAGCAATCCCGAGACTACG
GATATACCCGTGATTATCATGTCCGCCCTAAGCGATATGCAAAGCATCGTGAAAGGTTACCAATTGGGCGCCACCGAATA
CGTCACAAAGCCTTTCCAACGTGAGGAGCTGGTGAAGAGGGTGGCCCACCGCTACGAGCTTTACAGCATCAAGCGCATCA
AGGCCGAGCTGGAGAACACGATCGAGTCTAGGGATACGCTATACTCCGTTATCGCCCATGACCTGCGTTCCCCGCTAGGC
TCGTTGAAAATGATGAATAACGCCATCTTGATGATGGTGGACAAGGAGCGGGTAGGCGACGAGGTGTACGAGATGATCCA
GATGATGAACAAGACCTCCGAGGAGATCTTCCTCTTGCTGGACAACCTGCTGAAATGGGCCAAGAACCGCTTGAACAAGC
AGCACGTATATAAGCAACAGACCGACATAAACAGTATCATCGACAGTACCGCCGAGATGTATGTCCCGATGGCGGCGCAA
AAAGGCGTGAAGATTATCCTAGAAAATCTGGATAAAGAGCTGGTAGGCTTGGTCGATATCGATATGCTCAAGACGATTAT
CCGTAACCTGATCTCTAACGCCATGAAGTTTAGTTTCGAGGGGGGCACGATCACCTTATCCTCACGCTCCGAGGGGGATT
TCGTAACCGTTAGCGTGAAAGATACCGGCAAGGGCATCAAGAAAGAGGATCAAGACAAGCTCTTGAAACAAGACTCGCAT
TTCACGACCTACGGGACGAAGAACGAGAAAGGCTCCGGTCTGGGATTGATGCTTTGCAAGGACTTCGTGGAGCTTCATGG
AGGAAAGCTTTGGTTCGAGTCCGAGGGCGAGGGCAAAGGAACGACCTTCCTGTTCTCGATGAAGGCGCTGAACCAAGAGG
CATAG

Upstream 100 bases:

>100_bases
ATAGATGGATAAATAGTCGTTATATGTCGACTTTAATTAATACTTTTGCGCTATTGATACTATTTGAATATCAAGAAAAC
TAGAACACAATTTAGATACA

Downstream 100 bases:

>100_bases
CCGATCGACGTACCGCCTGTCCCTACCGATCGTAGACAAGTGTCGTACAAACAAACTAAATATTTCGTATATTTGCATCC
CGGATTAATATCCGGGATTT

Product: two-component hybrid sensor kinase/response regulator

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MDKLASEYKVLIVDDVPTNVMLVQAILKKEGYTLLTCDSGTKALRIANEKHPNLILLDIMMPEMDGYEVLQHLKSNPETT
DIPVIIMSALSDMQSIVKGYQLGATEYVTKPFQREELVKRVAHRYELYSIKRIKAELENTIESRDTLYSVIAHDLRSPLG
SLKMMNNAILMMVDKERVGDEVYEMIQMMNKTSEEIFLLLDNLLKWAKNRLNKQHVYKQQTDINSIIDSTAEMYVPMAAQ
KGVKIILENLDKELVGLVDIDMLKTIIRNLISNAMKFSFEGGTITLSSRSEGDFVTVSVKDTGKGIKKEDQDKLLKQDSH
FTTYGTKNEKGSGLGLMLCKDFVELHGGKLWFESEGEGKGTTFLFSMKALNQEA

Sequences:

>Translated_374_residues
MDKLASEYKVLIVDDVPTNVMLVQAILKKEGYTLLTCDSGTKALRIANEKHPNLILLDIMMPEMDGYEVLQHLKSNPETT
DIPVIIMSALSDMQSIVKGYQLGATEYVTKPFQREELVKRVAHRYELYSIKRIKAELENTIESRDTLYSVIAHDLRSPLG
SLKMMNNAILMMVDKERVGDEVYEMIQMMNKTSEEIFLLLDNLLKWAKNRLNKQHVYKQQTDINSIIDSTAEMYVPMAAQ
KGVKIILENLDKELVGLVDIDMLKTIIRNLISNAMKFSFEGGTITLSSRSEGDFVTVSVKDTGKGIKKEDQDKLLKQDSH
FTTYGTKNEKGSGLGLMLCKDFVELHGGKLWFESEGEGKGTTFLFSMKALNQEA
>Mature_374_residues
MDKLASEYKVLIVDDVPTNVMLVQAILKKEGYTLLTCDSGTKALRIANEKHPNLILLDIMMPEMDGYEVLQHLKSNPETT
DIPVIIMSALSDMQSIVKGYQLGATEYVTKPFQREELVKRVAHRYELYSIKRIKAELENTIESRDTLYSVIAHDLRSPLG
SLKMMNNAILMMVDKERVGDEVYEMIQMMNKTSEEIFLLLDNLLKWAKNRLNKQHVYKQQTDINSIIDSTAEMYVPMAAQ
KGVKIILENLDKELVGLVDIDMLKTIIRNLISNAMKFSFEGGTITLSSRSEGDFVTVSVKDTGKGIKKEDQDKLLKQDSH
FTTYGTKNEKGSGLGLMLCKDFVELHGGKLWFESEGEGKGTTFLFSMKALNQEA

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=29.0322580645161, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=25.6302521008403, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=263, Percent_Identity=27.3764258555133, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=26.4227642276423, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=35.3982300884956, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788550, Length=124, Percent_Identity=33.8709677419355, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=123, Percent_Identity=34.9593495934959, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=36.6666666666667, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082012, Length=146, Percent_Identity=31.5068493150685, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=28.6343612334802, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788393, Length=266, Percent_Identity=23.3082706766917, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786784, Length=113, Percent_Identity=32.7433628318584, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=227, Percent_Identity=27.3127753303965, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=23.2142857142857, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787229, Length=114, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=21.7557251908397, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=29.7520661157025, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081816, Length=270, Percent_Identity=24.4444444444444, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788905, Length=113, Percent_Identity=32.7433628318584, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=23.8297872340426, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790551, Length=312, Percent_Identity=25.3205128205128, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789809, Length=114, Percent_Identity=28.0701754385965, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790552, Length=120, Percent_Identity=34.1666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788394, Length=113, Percent_Identity=30.0884955752212, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 42311; Mature: 42311

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLASEYKVLIVDDVPTNVMLVQAILKKEGYTLLTCDSGTKALRIANEKHPNLILLDIM
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEEEE
MPEMDGYEVLQHLKSNPETTDIPVIIMSALSDMQSIVKGYQLGATEYVTKPFQREELVKR
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHH
VAHRYELYSIKRIKAELENTIESRDTLYSVIAHDLRSPLGSLKMMNNAILMMVDKERVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHH
EVYEMIQMMNKTSEEIFLLLDNLLKWAKNRLNKQHVYKQQTDINSIIDSTAEMYVPMAAQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KGVKIILENLDKELVGLVDIDMLKTIIRNLISNAMKFSFEGGTITLSSRSEGDFVTVSVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCCEEEEEEE
DTGKGIKKEDQDKLLKQDSHFTTYGTKNEKGSGLGLMLCKDFVELHGGKLWFESEGEGKG
CCCCCCCCCHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCC
TTFLFSMKALNQEA
CEEEEEEHHCCCCC
>Mature Secondary Structure
MDKLASEYKVLIVDDVPTNVMLVQAILKKEGYTLLTCDSGTKALRIANEKHPNLILLDIM
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEEEE
MPEMDGYEVLQHLKSNPETTDIPVIIMSALSDMQSIVKGYQLGATEYVTKPFQREELVKR
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHH
VAHRYELYSIKRIKAELENTIESRDTLYSVIAHDLRSPLGSLKMMNNAILMMVDKERVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHH
EVYEMIQMMNKTSEEIFLLLDNLLKWAKNRLNKQHVYKQQTDINSIIDSTAEMYVPMAAQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KGVKIILENLDKELVGLVDIDMLKTIIRNLISNAMKFSFEGGTITLSSRSEGDFVTVSVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCCEEEEEEE
DTGKGIKKEDQDKLLKQDSHFTTYGTKNEKGSGLGLMLCKDFVELHGGKLWFESEGEGKG
CCCCCCCCCHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCC
TTFLFSMKALNQEA
CEEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA