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The map label for this gene is dnaC [H]

Identifier: 150007928

GI number: 150007928

Start: 1499107

End: 1500561

Strand: Direct

Name: dnaC [H]

Synonym: BDI_1289

Alternate gene names: 150007928

Gene position: 1499107-1500561 (Clockwise)

Preceding gene: 150007927

Following gene: 150007929

Centisome position: 31.16

GC content: 63.16

Gene sequence:

>1455_bases
ATGGCAAACACGAGCAAAAACAAGAACGACCGCCCGGCGACACTGCCCGACGGCCTCGCCCTCCCGCAGGAGCAGGAGAT
CGAGAAAGCGATCTTATCGGGGCTTATGGCCTCCCATCGGCATATGCCCACGCTGGCGGCGCAACTGCTGCCGGAGATGT
TCACGCTACCGCAAGTGGCGATGGCCTTCGAGGCGTACCTGAACATCTACAACCGGGGGGAGAGCGCCGACGCCCTCTCC
GTGGAGAAGGAGCTGCGGAGGATAGCGCCCGATAAGGAGACGCTGGCCACCGACCTGTACCAGCTGGCGCTGGGCGGACG
GTATCTGGAAACCGGCGACGAGTACATGCCTACCCACGCACGCCACCTGCGGGAGGCCTACGTAGCGAGGCAGTTCATGC
TGAGCTGCTACGACTCGGCCTTGAAAGCCTCACGGCCGGATCGTGACACGGAGGCCTTGCTGAAGGAGATGGACTCGCAC
GTGGGCCGGCTGATGGAACGGCTCTCGCACGCCACGAACAGCATAGGCATGAAGGAAGCCACCCTGCTGGCCAAGGAGCG
CATGCTGGAGATACAACGCAGGGTGACGGAAGGACGCACGCCGGGCATACATACCGGCCTGGAGGGATTGGACCGGATGA
CGGGCGGCATGATGCCGGGCACGCTCAACGTGATCGCCGCACGCCCCCGGGTAGGCAAGACGGCCTTCGCCCTCTTCATG
GCGCTGAACGCAGCGAGGAACGGGCACCCGGTCTGCCTCTACAGCCTAGAGATGTCGAAGGAGCAGCTGGTGTTCAGGCT
GCTGGGATGCATAGCGGACATAGAGCCCTCCAAGATCCTGAAAGGGACCCTCTCCGCCCCCGAGATGAAGAGGATACAAA
GGGCCTCCGACGAGCTGGAGCGACTGCCGATATGGATCGACGAGCGCACGGACCTGAGCGTGGCCGACCTGCGTTACCAG
ATCTCGCTCCGGCGGAAGCAGGGGCGGTGCGAGATGGTGATCGTGGACTACCTCCAACTGATGCTCTCGCCTTCCGAGGA
CCGCAAGAGCACGAACGACCAGATATCGGCCATCACCCGGCAGCTAAAGCTGATCGCCAAGGAGAACGACATCCCCGTCG
TGCTGCTGAGCCAGCTGAACCGGAATTGCGAGGCGAGACCCACGCTGAAGAACATGCTGTCCGACCTGCGTGACTCCGGC
TCCATCGAGCAAGACGCCGATACGGTATTCTTCCTCCGCCGCCTCTCCGTGATGAACATCGACGAGGACCCGGAGACCCG
TCTCTCCACCGAGGGCCGGGGTACCCTCTCGATCGCCAAGAACCGGCACGGGGAGTCCGGGGAGGTGCGTTTCTGCCACA
ACAAGGGGGTAACCCGGTTCACCGATGACCGCACGCCGGTGCCGAACGACCGCAGACCGGCGAAAGCAGAACTGGATAAA
GACCTGTTCGGATGA

Upstream 100 bases:

>100_bases
AGGAAACGGCCTCGCCATCAAGGTACCCTTCTACAAGTCCCTCTTCATCAAGGAGGAGAAGATACAGAAAGATAACGACA
AACAAGAACAGGAGTAAAGC

Downstream 100 bases:

>100_bases
TCACGCATGACACTTTACTGCGGGTACGGGAAACCGCCCGCATCGACGAGGTAGCGGCCGGGTACCTCACACTACGGCGT
TCCGGCAAGGGTCTCGTGGC

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MANTSKNKNDRPATLPDGLALPQEQEIEKAILSGLMASHRHMPTLAAQLLPEMFTLPQVAMAFEAYLNIYNRGESADALS
VEKELRRIAPDKETLATDLYQLALGGRYLETGDEYMPTHARHLREAYVARQFMLSCYDSALKASRPDRDTEALLKEMDSH
VGRLMERLSHATNSIGMKEATLLAKERMLEIQRRVTEGRTPGIHTGLEGLDRMTGGMMPGTLNVIAARPRVGKTAFALFM
ALNAARNGHPVCLYSLEMSKEQLVFRLLGCIADIEPSKILKGTLSAPEMKRIQRASDELERLPIWIDERTDLSVADLRYQ
ISLRRKQGRCEMVIVDYLQLMLSPSEDRKSTNDQISAITRQLKLIAKENDIPVVLLSQLNRNCEARPTLKNMLSDLRDSG
SIEQDADTVFFLRRLSVMNIDEDPETRLSTEGRGTLSIAKNRHGESGEVRFCHNKGVTRFTDDRTPVPNDRRPAKAELDK
DLFG

Sequences:

>Translated_484_residues
MANTSKNKNDRPATLPDGLALPQEQEIEKAILSGLMASHRHMPTLAAQLLPEMFTLPQVAMAFEAYLNIYNRGESADALS
VEKELRRIAPDKETLATDLYQLALGGRYLETGDEYMPTHARHLREAYVARQFMLSCYDSALKASRPDRDTEALLKEMDSH
VGRLMERLSHATNSIGMKEATLLAKERMLEIQRRVTEGRTPGIHTGLEGLDRMTGGMMPGTLNVIAARPRVGKTAFALFM
ALNAARNGHPVCLYSLEMSKEQLVFRLLGCIADIEPSKILKGTLSAPEMKRIQRASDELERLPIWIDERTDLSVADLRYQ
ISLRRKQGRCEMVIVDYLQLMLSPSEDRKSTNDQISAITRQLKLIAKENDIPVVLLSQLNRNCEARPTLKNMLSDLRDSG
SIEQDADTVFFLRRLSVMNIDEDPETRLSTEGRGTLSIAKNRHGESGEVRFCHNKGVTRFTDDRTPVPNDRRPAKAELDK
DLFG
>Mature_483_residues
ANTSKNKNDRPATLPDGLALPQEQEIEKAILSGLMASHRHMPTLAAQLLPEMFTLPQVAMAFEAYLNIYNRGESADALSV
EKELRRIAPDKETLATDLYQLALGGRYLETGDEYMPTHARHLREAYVARQFMLSCYDSALKASRPDRDTEALLKEMDSHV
GRLMERLSHATNSIGMKEATLLAKERMLEIQRRVTEGRTPGIHTGLEGLDRMTGGMMPGTLNVIAARPRVGKTAFALFMA
LNAARNGHPVCLYSLEMSKEQLVFRLLGCIADIEPSKILKGTLSAPEMKRIQRASDELERLPIWIDERTDLSVADLRYQI
SLRRKQGRCEMVIVDYLQLMLSPSEDRKSTNDQISAITRQLKLIAKENDIPVVLLSQLNRNCEARPTLKNMLSDLRDSGS
IEQDADTVFFLRRLSVMNIDEDPETRLSTEGRGTLSIAKNRHGESGEVRFCHNKGVTRFTDDRTPVPNDRRPAKAELDKD
LFG

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=468, Percent_Identity=31.1965811965812, Blast_Score=174, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 54448; Mature: 54317

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTSKNKNDRPATLPDGLALPQEQEIEKAILSGLMASHRHMPTLAAQLLPEMFTLPQVA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
MAFEAYLNIYNRGESADALSVEKELRRIAPDKETLATDLYQLALGGRYLETGDEYMPTHA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
RHLREAYVARQFMLSCYDSALKASRPDRDTEALLKEMDSHVGRLMERLSHATNSIGMKEA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TLLAKERMLEIQRRVTEGRTPGIHTGLEGLDRMTGGMMPGTLNVIAARPRVGKTAFALFM
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHH
ALNAARNGHPVCLYSLEMSKEQLVFRLLGCIADIEPSKILKGTLSAPEMKRIQRASDELE
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHH
RLPIWIDERTDLSVADLRYQISLRRKQGRCEMVIVDYLQLMLSPSEDRKSTNDQISAITR
HCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCCHHHHHHHHH
QLKLIAKENDIPVVLLSQLNRNCEARPTLKNMLSDLRDSGSIEQDADTVFFLRRLSVMNI
HHHHHHCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
DEDPETRLSTEGRGTLSIAKNRHGESGEVRFCHNKGVTRFTDDRTPVPNDRRPAKAELDK
CCCCCHHCCCCCCCEEEECCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCCHHHHHH
DLFG
HCCC
>Mature Secondary Structure 
ANTSKNKNDRPATLPDGLALPQEQEIEKAILSGLMASHRHMPTLAAQLLPEMFTLPQVA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
MAFEAYLNIYNRGESADALSVEKELRRIAPDKETLATDLYQLALGGRYLETGDEYMPTHA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
RHLREAYVARQFMLSCYDSALKASRPDRDTEALLKEMDSHVGRLMERLSHATNSIGMKEA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TLLAKERMLEIQRRVTEGRTPGIHTGLEGLDRMTGGMMPGTLNVIAARPRVGKTAFALFM
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHH
ALNAARNGHPVCLYSLEMSKEQLVFRLLGCIADIEPSKILKGTLSAPEMKRIQRASDELE
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHH
RLPIWIDERTDLSVADLRYQISLRRKQGRCEMVIVDYLQLMLSPSEDRKSTNDQISAITR
HCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCCHHHHHHHHH
QLKLIAKENDIPVVLLSQLNRNCEARPTLKNMLSDLRDSGSIEQDADTVFFLRRLSVMNI
HHHHHHCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
DEDPETRLSTEGRGTLSIAKNRHGESGEVRFCHNKGVTRFTDDRTPVPNDRRPAKAELDK
CCCCCHHCCCCCCCEEEECCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCCHHHHHH
DLFG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]