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The map label for this gene is recQ [H]

Identifier: 150007804

GI number: 150007804

Start: 1349475

End: 1351310

Strand: Direct

Name: recQ [H]

Synonym: BDI_1162

Alternate gene names: 150007804

Gene position: 1349475-1351310 (Clockwise)

Preceding gene: 150007793

Following gene: 150007805

Centisome position: 28.05

GC content: 56.54

Gene sequence:

>1836_bases
ATGAAAGAATTATTACTACTACTGAAAAAGTTCTTCGGATATACCTCCTTCCGTCCCTTGCAGGCGGACATCATACAGCG
TATCTTACAGAAAGAGGACTCGTTGGTGCTGATGCCCACGGGTGGAGGCAAGTCGATCTGTTTTCAGCTACCGGCTATCT
ATCTGCCGGGTACGGCTTTGGTGGTGTCCCCCTTGATCGCCTTGATGAAGGATCAAGTAGAGGGGTTGATCGCCAACGGC
ATCCCTGCGGCGGCGTTGAACAGTATGATGCCGGAAGAGGAGCAACAACAGGTGAAGCAACTTTGCGTGCAGGGCAAGAT
CAAATTATTGTATATCTCCCCGGAACGGATCAAGATGGAAGCGGACTGGTTCCTGCCCCGGCTGGACATCTCGCTCATCG
CTATCGACGAGGCGCATTGCGTATCGCATTGGGGACATGACTTCCGTCCGGAATACACGCAACTGGCGATCTTGAAGGAG
CGTTTCCCGAAAGTCCCGGTCGTGGCCCTGACCGCTACCGCCGATAAAATCACCCGGAAGGATATCCTAGAGCAGTTACG
ACTTCGCACGCCCCAAACGTTCATATCGTCATTCGACCGCCCGAACATCTCCCTCACGGTACGCCGGGGGCTTAACAAGA
AAGAGAAGATCGCCGCCATCGTCCATTTCATCCGGGGGCACCGGGAGCAGAGCGGTATCATCTATTGCATGCGCCGCAAC
GATACGACCGAGCTGGCTGATGAGTTGGCGATGTATAATATCAAGGCGATCGCCTACCACGCCGGCCTCCTGCCCGCCCA
ACGGGAACAGGCCCAGAACGACTTCATCAACGACCGGGTGGACGTGGTGTGCGCCACGGTAGCTTTCGGGATGGGTATCG
ACAAGAGCAATGTCCGCTGGGTCGTGCATTACAGCATGCCGGGGAGTATCGAGAATTACTACCAAGAGATCGGCCGTGCC
GGAAGGGACGGGATGAAAAGCGATACCCTCCTGTTCTATTCCTTGAGCGACTTGATCGTACTTCGTCGTTTCGCCGAGGA
GAGTGGCCAAAGCGAGGTGAACTTGGAGAAGCTAAACCGGATGAGACGGTATTGCGAGTCCGATATGTGCCGCCGCCGTG
TCCTGCTCAGTTACTTCGGCGAGGAGGCGGACCATGATTGCGGCAACTGCGACGTGTGCAAGAACCCTCCGCAACGTTTC
GACGGCAGTGTCTTGATACAAAAGGCGCTGAGCGCCGTTATCCGGACCGGCGAGCACGTGGGCATGCAGATGCTGATCGA
CATACTCCGTGCCTCCGCCCGCACGGAGCTGCTGGAGAGAGGATACGATAAGCTAAAGACGTACGGAGCCGGACGGGATC
TCTCTTATAAAGAATGGAAGGAGTACATTTACCAGATGATCCAACTCGGGTACATGGAGATCGACTACGCCGCCGAGCGT
GTCTTGCGGATGACCCCGCTAGGCAGGCGTGTCCTGTACGGGGAGCAAAAGGCCCAGCTCGTCATCTATCGGGAACCGGA
TGAGCTGACACGCCCCGTCCGGAGAGGCGAGCGGAAATCCTCCTTCAAGGCCCAGCCGATCCGGCCGATCCGGTCCGCCT
CTACGGACGAGACCTTGCTGGACTCCCTCCGCCAACTTCGCAAGCAAATCGCCGAGCGAGAGCATACGCCGGCTTATATC
ATCTTCTCCGACGATTCTTTGGAAGACATGGTGGAGAAGAAACCGGTCACCTTGGACCAGTTCAGCGACATCCGGGGCGT
GGGGCAAATCAAGCTGGACCGGTATGGGAAGGTGTTCGTGGCCTTGATCCGGTTCGTGCTGAAGCTACCGAAATAA

Upstream 100 bases:

>100_bases
AGGGTGAGCCATCACGGCTCGTTATGTAAATAATGTGGGCAAAGGTAGTAAAACTTTATGATATAAACTATCTTTGCGCT
TTTTATGCCCGTAAAGCGAT

Downstream 100 bases:

>100_bases
GAAGAACACATGTTAATGTTTTTAGCTCCTAAATGGAAATATAAAAAAATCACATATATTTGTCTACAATTATTAAGCAC
AATGCCTCATATTCATGATA

Product: putative ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MKELLLLLKKFFGYTSFRPLQADIIQRILQKEDSLVLMPTGGGKSICFQLPAIYLPGTALVVSPLIALMKDQVEGLIANG
IPAAALNSMMPEEEQQQVKQLCVQGKIKLLYISPERIKMEADWFLPRLDISLIAIDEAHCVSHWGHDFRPEYTQLAILKE
RFPKVPVVALTATADKITRKDILEQLRLRTPQTFISSFDRPNISLTVRRGLNKKEKIAAIVHFIRGHREQSGIIYCMRRN
DTTELADELAMYNIKAIAYHAGLLPAQREQAQNDFINDRVDVVCATVAFGMGIDKSNVRWVVHYSMPGSIENYYQEIGRA
GRDGMKSDTLLFYSLSDLIVLRRFAEESGQSEVNLEKLNRMRRYCESDMCRRRVLLSYFGEEADHDCGNCDVCKNPPQRF
DGSVLIQKALSAVIRTGEHVGMQMLIDILRASARTELLERGYDKLKTYGAGRDLSYKEWKEYIYQMIQLGYMEIDYAAER
VLRMTPLGRRVLYGEQKAQLVIYREPDELTRPVRRGERKSSFKAQPIRPIRSASTDETLLDSLRQLRKQIAEREHTPAYI
IFSDDSLEDMVEKKPVTLDQFSDIRGVGQIKLDRYGKVFVALIRFVLKLPK

Sequences:

>Translated_611_residues
MKELLLLLKKFFGYTSFRPLQADIIQRILQKEDSLVLMPTGGGKSICFQLPAIYLPGTALVVSPLIALMKDQVEGLIANG
IPAAALNSMMPEEEQQQVKQLCVQGKIKLLYISPERIKMEADWFLPRLDISLIAIDEAHCVSHWGHDFRPEYTQLAILKE
RFPKVPVVALTATADKITRKDILEQLRLRTPQTFISSFDRPNISLTVRRGLNKKEKIAAIVHFIRGHREQSGIIYCMRRN
DTTELADELAMYNIKAIAYHAGLLPAQREQAQNDFINDRVDVVCATVAFGMGIDKSNVRWVVHYSMPGSIENYYQEIGRA
GRDGMKSDTLLFYSLSDLIVLRRFAEESGQSEVNLEKLNRMRRYCESDMCRRRVLLSYFGEEADHDCGNCDVCKNPPQRF
DGSVLIQKALSAVIRTGEHVGMQMLIDILRASARTELLERGYDKLKTYGAGRDLSYKEWKEYIYQMIQLGYMEIDYAAER
VLRMTPLGRRVLYGEQKAQLVIYREPDELTRPVRRGERKSSFKAQPIRPIRSASTDETLLDSLRQLRKQIAEREHTPAYI
IFSDDSLEDMVEKKPVTLDQFSDIRGVGQIKLDRYGKVFVALIRFVLKLPK
>Mature_611_residues
MKELLLLLKKFFGYTSFRPLQADIIQRILQKEDSLVLMPTGGGKSICFQLPAIYLPGTALVVSPLIALMKDQVEGLIANG
IPAAALNSMMPEEEQQQVKQLCVQGKIKLLYISPERIKMEADWFLPRLDISLIAIDEAHCVSHWGHDFRPEYTQLAILKE
RFPKVPVVALTATADKITRKDILEQLRLRTPQTFISSFDRPNISLTVRRGLNKKEKIAAIVHFIRGHREQSGIIYCMRRN
DTTELADELAMYNIKAIAYHAGLLPAQREQAQNDFINDRVDVVCATVAFGMGIDKSNVRWVVHYSMPGSIENYYQEIGRA
GRDGMKSDTLLFYSLSDLIVLRRFAEESGQSEVNLEKLNRMRRYCESDMCRRRVLLSYFGEEADHDCGNCDVCKNPPQRF
DGSVLIQKALSAVIRTGEHVGMQMLIDILRASARTELLERGYDKLKTYGAGRDLSYKEWKEYIYQMIQLGYMEIDYAAER
VLRMTPLGRRVLYGEQKAQLVIYREPDELTRPVRRGERKSSFKAQPIRPIRSASTDETLLDSLRQLRKQIAEREHTPAYI
IFSDDSLEDMVEKKPVTLDQFSDIRGVGQIKLDRYGKVFVALIRFVLKLPK

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=648, Percent_Identity=35.9567901234568, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI110735439, Length=685, Percent_Identity=32.2627737226277, Blast_Score=329, Evalue=6e-90,
Organism=Homo sapiens, GI169218196, Length=685, Percent_Identity=32.1167883211679, Blast_Score=328, Evalue=7e-90,
Organism=Homo sapiens, GI14591902, Length=401, Percent_Identity=40.6483790523691, Blast_Score=295, Evalue=8e-80,
Organism=Homo sapiens, GI14591904, Length=401, Percent_Identity=40.6483790523691, Blast_Score=295, Evalue=8e-80,
Organism=Homo sapiens, GI148612816, Length=423, Percent_Identity=36.1702127659575, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI51242947, Length=353, Percent_Identity=39.6600566572238, Blast_Score=250, Evalue=3e-66,
Organism=Homo sapiens, GI51242943, Length=353, Percent_Identity=39.6600566572238, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI284005309, Length=357, Percent_Identity=36.4145658263305, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI222352149, Length=361, Percent_Identity=24.0997229916898, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI48994977, Length=604, Percent_Identity=44.7019867549669, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI87082221, Length=356, Percent_Identity=26.4044943820225, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787016, Length=360, Percent_Identity=22.7777777777778, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=655, Percent_Identity=34.0458015267176, Blast_Score=322, Evalue=5e-88,
Organism=Caenorhabditis elegans, GI32564293, Length=670, Percent_Identity=33.4328358208955, Blast_Score=308, Evalue=6e-84,
Organism=Caenorhabditis elegans, GI71987997, Length=409, Percent_Identity=41.0757946210269, Blast_Score=305, Evalue=6e-83,
Organism=Caenorhabditis elegans, GI71987993, Length=409, Percent_Identity=41.0757946210269, Blast_Score=304, Evalue=9e-83,
Organism=Caenorhabditis elegans, GI17552866, Length=487, Percent_Identity=35.523613963039, Blast_Score=276, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17537549, Length=362, Percent_Identity=23.2044198895028, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323844, Length=631, Percent_Identity=32.6465927099841, Blast_Score=337, Evalue=4e-93,
Organism=Saccharomyces cerevisiae, GI6320224, Length=358, Percent_Identity=25.1396648044693, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325138, Length=132, Percent_Identity=28.030303030303, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646066, Length=637, Percent_Identity=34.3799058084772, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24664226, Length=428, Percent_Identity=34.8130841121495, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24664230, Length=428, Percent_Identity=34.8130841121495, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI62472181, Length=428, Percent_Identity=34.8130841121495, Blast_Score=253, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21358123, Length=355, Percent_Identity=36.6197183098592, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21355075, Length=381, Percent_Identity=21.7847769028871, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 70043; Mature: 70043

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELLLLLKKFFGYTSFRPLQADIIQRILQKEDSLVLMPTGGGKSICFQLPAIYLPGTAL
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCHHH
VVSPLIALMKDQVEGLIANGIPAAALNSMMPEEEQQQVKQLCVQGKIKLLYISPERIKME
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECHHHEEEE
ADWFLPRLDISLIAIDEAHCVSHWGHDFRPEYTQLAILKERFPKVPVVALTATADKITRK
HHHCCEECCEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHH
DILEQLRLRTPQTFISSFDRPNISLTVRRGLNKKEKIAAIVHFIRGHREQSGIIYCMRRN
HHHHHHHCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECC
DTTELADELAMYNIKAIAYHAGLLPAQREQAQNDFINDRVDVVCATVAFGMGIDKSNVRW
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEE
VVHYSMPGSIENYYQEIGRAGRDGMKSDTLLFYSLSDLIVLRRFAEESGQSEVNLEKLNR
EEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHH
MRRYCESDMCRRRVLLSYFGEEADHDCGNCDVCKNPPQRFDGSVLIQKALSAVIRTGEHV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
GMQMLIDILRASARTELLERGYDKLKTYGAGRDLSYKEWKEYIYQMIQLGYMEIDYAAER
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
VLRMTPLGRRVLYGEQKAQLVIYREPDELTRPVRRGERKSSFKAQPIRPIRSASTDETLL
HHHHCCCCCHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHH
DSLRQLRKQIAEREHTPAYIIFSDDSLEDMVEKKPVTLDQFSDIRGVGQIKLDRYGKVFV
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCHHHHHHCCCCCCEEHHHHHHHHH
ALIRFVLKLPK
HHHHHHHHCCC
>Mature Secondary Structure
MKELLLLLKKFFGYTSFRPLQADIIQRILQKEDSLVLMPTGGGKSICFQLPAIYLPGTAL
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCHHH
VVSPLIALMKDQVEGLIANGIPAAALNSMMPEEEQQQVKQLCVQGKIKLLYISPERIKME
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECHHHEEEE
ADWFLPRLDISLIAIDEAHCVSHWGHDFRPEYTQLAILKERFPKVPVVALTATADKITRK
HHHCCEECCEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHH
DILEQLRLRTPQTFISSFDRPNISLTVRRGLNKKEKIAAIVHFIRGHREQSGIIYCMRRN
HHHHHHHCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECC
DTTELADELAMYNIKAIAYHAGLLPAQREQAQNDFINDRVDVVCATVAFGMGIDKSNVRW
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEE
VVHYSMPGSIENYYQEIGRAGRDGMKSDTLLFYSLSDLIVLRRFAEESGQSEVNLEKLNR
EEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHH
MRRYCESDMCRRRVLLSYFGEEADHDCGNCDVCKNPPQRFDGSVLIQKALSAVIRTGEHV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
GMQMLIDILRASARTELLERGYDKLKTYGAGRDLSYKEWKEYIYQMIQLGYMEIDYAAER
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
VLRMTPLGRRVLYGEQKAQLVIYREPDELTRPVRRGERKSSFKAQPIRPIRSASTDETLL
HHHHCCCCCHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHH
DSLRQLRKQIAEREHTPAYIIFSDDSLEDMVEKKPVTLDQFSDIRGVGQIKLDRYGKVFV
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCHHHHHHCCCCCCEEHHHHHHHHH
ALIRFVLKLPK
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]