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The map label for this gene is rcsC [H]

Identifier: 150007794

GI number: 150007794

Start: 1331071

End: 1332969

Strand: Reverse

Name: rcsC [H]

Synonym: BDI_1152

Alternate gene names: 150007794

Gene position: 1332969-1331071 (Counterclockwise)

Preceding gene: 150007795

Following gene: 150007790

Centisome position: 27.7

GC content: 40.6

Gene sequence:

>1899_bases
ATGGAGGATATACAGACTCAATTGGATCAATGTAAATTGTTATTGGATAGGGCGGAAGTTGGCTTGTGGGAAGCCGATTT
TGTTCAAAGAAGTTATATCTGTTCCGATTATTTAATGAGTATATTTGGGAAGAAGGGGAATAATCTCTCTTTTTTTGAAT
TTTACTATATAATCCGGGAAGACTTTAGGGATCTGATTACTACGGATTTTTTATCGATCCAATCTGTCGATACGTATGAG
CAAATATTTCCGATAATAACACCGACTGGGGAAAAATGGGTACGCTCCAGATTATGTGAGCGTAAGTTGAATAACGGAGT
GTGCGTAAAAGCGTTGGGCATATTACAGATTTTACCTAATTTCAAACTGAAAGAGGAAAAGATTAGTAAGATGATCGATC
ATAATGAAATGATCTTCCGAAAGCTGTATGTAAATTTACCTGTGGGAGTCGAGCTTTATGACAGGGACGGTTACTTGATT
GATCTGAACGCAAAGGATATGGAGATATTCGGTATCCGGTCAAAGAAGGACGTTTTAGGAGTCAATATTTTTAGCAACCC
GATTCTGCCTAAAGATGTGATCAAGAAACTCAAGGAGAATAAATCCGTGAATTTCCGGCTGAATTATTCGTTTAAGAAGG
TCGATGATTATTATAACACCTCGAAAGTAGGCGAGTTGGATATCGTTACCAAGGCCAGTATTTTATATGACCAAAGAGGT
GAACCTTCCAGCTATTTACTTATTAATTTGGATAATACGGAAAAGATGATCGCCTATAACCGTATTTCTGAGTTTGAGAA
TGTATTTACCTTGGTCAGCGTATACGCTAAAGTCGGTTATGCCCTTTATGACTTATATACCTTTGAGGGCTATGCCATTA
AGCAATGGTATGAGAATATGGGAGAGAAGGATGGAACCCCCTTGTCCCAAATTATTGGGATTTATTCTTATATTCATCCG
AACGACGCTGGATATATAAACTCATTCTTTGAGGAGGTGAAACAGGGTAAAGCGCATCATTTCCGTAGGGAAGTGCGTGT
GAAGTCTGGTGACGGATGGAAATGGATTTGCGCCAATATCACCCGTAACCCTCAAAGCGTAGACCCGAATAAACCGGAGA
TGATCTGTATTAATTATGATATCACGGAGTTAAAGGACTCTCAATTGAAAAGGGAAAGGGCGGAAGAACTGGATCGTTTG
AAGTCTGCCTTCCTAGCGAATATGAGTCATGAGATTCGTACGCCATTAAATGCCATTGTCGGTTTTTCTCAATTATTGGC
GGAAACGGATGATCCCGAGGAGAGGCATGAGTTTGTGGAAATCATCGATAGCAATAATCGGATGTTGCTTCAATTGATCA
GTGATATTCTAGATTTGGCAAAAATTGAATCTGGTACGATGGATTTCAAGTTCGCCGATATGAGCATAAAAGAGGTGATC
AATGAGATCGTGACCTCTTTCCGTATTAAGATGCCCGATAACGTAGCTCTGATTGCTCCCAAAGATTCACCGGAATGCCA
AATCTATAGCGATCGTATGCGGCTGACGCAGGTAATTTCCAATTTCCTTAACAATGCGATCAAGTATACGAGCGAAGGTT
GTATCATCTTAGCTTACGAGATCATAGGTGATGAGATAAAATTCTCCGTGACTGATACGGGGGATGGCATGAGCCAAGAG
ATACAAGCCCATATCTTTGATCGTTTCTATAAAGGAAATACGTTTAAACAAGGTACGGGCTTGGGGCTATCTATTTGCGA
GACCATCGTAAATAGACTAGGTGGTCGGATCGGTGTAAATTCCGAGTTGGGCAAAGGCAGTACGTTTTGGTTTACACATC
CCTATTCCTTCTCGCCGAACGCTAAATCTCCTGCATCGCCTAATCCGGGAACGATATAA

Upstream 100 bases:

>100_bases
AGTTATTCGAGACAATCTCTTTTTTATTATAGAGGATTTATACTATTTAAATTATATCTTTGTGAAATCATAGTGTAATT
TTATCGGAAGGGATATTTTT

Downstream 100 bases:

>100_bases
GAATGATCGTCGAGGTCATTATCTAATGCGGCGATCCAGATTGTAGTCTTGTCATCCGGCATTTTCTTCTGCAAGTATTC
CAAGGCTTGTTTGCTTGAGA

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MEDIQTQLDQCKLLLDRAEVGLWEADFVQRSYICSDYLMSIFGKKGNNLSFFEFYYIIREDFRDLITTDFLSIQSVDTYE
QIFPIITPTGEKWVRSRLCERKLNNGVCVKALGILQILPNFKLKEEKISKMIDHNEMIFRKLYVNLPVGVELYDRDGYLI
DLNAKDMEIFGIRSKKDVLGVNIFSNPILPKDVIKKLKENKSVNFRLNYSFKKVDDYYNTSKVGELDIVTKASILYDQRG
EPSSYLLINLDNTEKMIAYNRISEFENVFTLVSVYAKVGYALYDLYTFEGYAIKQWYENMGEKDGTPLSQIIGIYSYIHP
NDAGYINSFFEEVKQGKAHHFRREVRVKSGDGWKWICANITRNPQSVDPNKPEMICINYDITELKDSQLKRERAEELDRL
KSAFLANMSHEIRTPLNAIVGFSQLLAETDDPEERHEFVEIIDSNNRMLLQLISDILDLAKIESGTMDFKFADMSIKEVI
NEIVTSFRIKMPDNVALIAPKDSPECQIYSDRMRLTQVISNFLNNAIKYTSEGCIILAYEIIGDEIKFSVTDTGDGMSQE
IQAHIFDRFYKGNTFKQGTGLGLSICETIVNRLGGRIGVNSELGKGSTFWFTHPYSFSPNAKSPASPNPGTI

Sequences:

>Translated_632_residues
MEDIQTQLDQCKLLLDRAEVGLWEADFVQRSYICSDYLMSIFGKKGNNLSFFEFYYIIREDFRDLITTDFLSIQSVDTYE
QIFPIITPTGEKWVRSRLCERKLNNGVCVKALGILQILPNFKLKEEKISKMIDHNEMIFRKLYVNLPVGVELYDRDGYLI
DLNAKDMEIFGIRSKKDVLGVNIFSNPILPKDVIKKLKENKSVNFRLNYSFKKVDDYYNTSKVGELDIVTKASILYDQRG
EPSSYLLINLDNTEKMIAYNRISEFENVFTLVSVYAKVGYALYDLYTFEGYAIKQWYENMGEKDGTPLSQIIGIYSYIHP
NDAGYINSFFEEVKQGKAHHFRREVRVKSGDGWKWICANITRNPQSVDPNKPEMICINYDITELKDSQLKRERAEELDRL
KSAFLANMSHEIRTPLNAIVGFSQLLAETDDPEERHEFVEIIDSNNRMLLQLISDILDLAKIESGTMDFKFADMSIKEVI
NEIVTSFRIKMPDNVALIAPKDSPECQIYSDRMRLTQVISNFLNNAIKYTSEGCIILAYEIIGDEIKFSVTDTGDGMSQE
IQAHIFDRFYKGNTFKQGTGLGLSICETIVNRLGGRIGVNSELGKGSTFWFTHPYSFSPNAKSPASPNPGTI
>Mature_632_residues
MEDIQTQLDQCKLLLDRAEVGLWEADFVQRSYICSDYLMSIFGKKGNNLSFFEFYYIIREDFRDLITTDFLSIQSVDTYE
QIFPIITPTGEKWVRSRLCERKLNNGVCVKALGILQILPNFKLKEEKISKMIDHNEMIFRKLYVNLPVGVELYDRDGYLI
DLNAKDMEIFGIRSKKDVLGVNIFSNPILPKDVIKKLKENKSVNFRLNYSFKKVDDYYNTSKVGELDIVTKASILYDQRG
EPSSYLLINLDNTEKMIAYNRISEFENVFTLVSVYAKVGYALYDLYTFEGYAIKQWYENMGEKDGTPLSQIIGIYSYIHP
NDAGYINSFFEEVKQGKAHHFRREVRVKSGDGWKWICANITRNPQSVDPNKPEMICINYDITELKDSQLKRERAEELDRL
KSAFLANMSHEIRTPLNAIVGFSQLLAETDDPEERHEFVEIIDSNNRMLLQLISDILDLAKIESGTMDFKFADMSIKEVI
NEIVTSFRIKMPDNVALIAPKDSPECQIYSDRMRLTQVISNFLNNAIKYTSEGCIILAYEIIGDEIKFSVTDTGDGMSQE
IQAHIFDRFYKGNTFKQGTGLGLSICETIVNRLGGRIGVNSELGKGSTFWFTHPYSFSPNAKSPASPNPGTI

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=37.109375, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=34.4262295081967, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788713, Length=258, Percent_Identity=35.2713178294574, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=35.8565737051793, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI48994928, Length=254, Percent_Identity=31.8897637795276, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=28.9795918367347, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30.4166666666667, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=28.0851063829787, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=31.0483870967742, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790861, Length=308, Percent_Identity=25.3246753246753, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786600, Length=250, Percent_Identity=24.4, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=27.4678111587983, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=209, Percent_Identity=26.7942583732057, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790300, Length=206, Percent_Identity=26.6990291262136, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788279, Length=276, Percent_Identity=25.7246376811594, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72548; Mature: 72548

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDIQTQLDQCKLLLDRAEVGLWEADFVQRSYICSDYLMSIFGKKGNNLSFFEFYYIIRE
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DFRDLITTDFLSIQSVDTYEQIFPIITPTGEKWVRSRLCERKLNNGVCVKALGILQILPN
HHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
FKLKEEKISKMIDHNEMIFRKLYVNLPVGVELYDRDGYLIDLNAKDMEIFGIRSKKDVLG
CCCCHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCCEEE
VNIFSNPILPKDVIKKLKENKSVNFRLNYSFKKVDDYYNTSKVGELDIVTKASILYDQRG
EEECCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCCCEEEEEHHHHHCCCCC
EPSSYLLINLDNTEKMIAYNRISEFENVFTLVSVYAKVGYALYDLYTFEGYAIKQWYENM
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GEKDGTPLSQIIGIYSYIHPNDAGYINSFFEEVKQGKAHHFRREVRVKSGDGWKWICANI
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHEEECCCCCEEEEEEC
TRNPQSVDPNKPEMICINYDITELKDSQLKRERAEELDRLKSAFLANMSHEIRTPLNAIV
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHH
GFSQLLAETDDPEERHEFVEIIDSNNRMLLQLISDILDLAKIESGTMDFKFADMSIKEVI
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
NEIVTSFRIKMPDNVALIAPKDSPECQIYSDRMRLTQVISNFLNNAIKYTSEGCIILAYE
HHHHHHEEEECCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IIGDEIKFSVTDTGDGMSQEIQAHIFDRFYKGNTFKQGTGLGLSICETIVNRLGGRIGVN
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
SELGKGSTFWFTHPYSFSPNAKSPASPNPGTI
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEDIQTQLDQCKLLLDRAEVGLWEADFVQRSYICSDYLMSIFGKKGNNLSFFEFYYIIRE
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DFRDLITTDFLSIQSVDTYEQIFPIITPTGEKWVRSRLCERKLNNGVCVKALGILQILPN
HHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
FKLKEEKISKMIDHNEMIFRKLYVNLPVGVELYDRDGYLIDLNAKDMEIFGIRSKKDVLG
CCCCHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCCEEE
VNIFSNPILPKDVIKKLKENKSVNFRLNYSFKKVDDYYNTSKVGELDIVTKASILYDQRG
EEECCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCCCEEEEEHHHHHCCCCC
EPSSYLLINLDNTEKMIAYNRISEFENVFTLVSVYAKVGYALYDLYTFEGYAIKQWYENM
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GEKDGTPLSQIIGIYSYIHPNDAGYINSFFEEVKQGKAHHFRREVRVKSGDGWKWICANI
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHEEECCCCCEEEEEEC
TRNPQSVDPNKPEMICINYDITELKDSQLKRERAEELDRLKSAFLANMSHEIRTPLNAIV
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHH
GFSQLLAETDDPEERHEFVEIIDSNNRMLLQLISDILDLAKIESGTMDFKFADMSIKEVI
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
NEIVTSFRIKMPDNVALIAPKDSPECQIYSDRMRLTQVISNFLNNAIKYTSEGCIILAYE
HHHHHHEEEECCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IIGDEIKFSVTDTGDGMSQEIQAHIFDRFYKGNTFKQGTGLGLSICETIVNRLGGRIGVN
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
SELGKGSTFWFTHPYSFSPNAKSPASPNPGTI
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]