Click here to switch to the map view.

The map label for this gene is murB [H]

Identifier: 150007790

GI number: 150007790

Start: 1327906

End: 1328919

Strand: Reverse

Name: murB [H]

Synonym: BDI_1148

Alternate gene names: 150007790

Gene position: 1328919-1327906 (Counterclockwise)

Preceding gene: 150007794

Following gene: 150007789

Centisome position: 27.62

GC content: 45.36

Gene sequence:

>1014_bases
ATGAGAATAGAGCAGAATTATTCGTTGGAGAAACACAATACGTTCCATCTCCCAGTAAAGACACGTTGGTTCATGGAGTA
TGAGACGGAGGAGGAGTTGCAACGAATCTTACATGATGAATACTTTCAGGAATGTTTATCCTTGCATATAGGAGGCGGGA
GCAATCTATTGTTCATCAACGATTATAATGGCATTATCATCCATTCCCGAATCAAGGGGATTTCTATCTCGGCGGAAACG
GACGAGTATGTATCGCTTCGTGTCGGGGCTGCGGAGATCTGGGATGATGTCGTGGCATACGCCGTATCGAAAGGTTGGGG
AGGTATAGAGAATCTTTCTTTAATACCCGGTGAGGCGGGCGCTGCCGCTATCCAGAACATCGGGGCTTATGGCATGGAGA
TCAAGGATGTGATCGAGAGCGTGGAGGCTTATAACCAGTTGACATTCGAGAAACGGACTTTTACGAATTCGGATTGTGAA
TATGGATATCGTAATAGTTATTTCAAGAATGAACATCATGACCCCCACATCATAACTTATATCACGCTTCGACTATCCAA
GAACCCTGGTTTTTCAGTTAATTATGGGAACTTAAAGGAGGAGTTGACGAAATATCCGGAAGTTACTTTGGAAACGATCC
GTGAGGCTGTCATAACAATTCGCAGGCAGAAGCTTCCCGATCCTGAAGTATTAGGCAACGCAGGCAGTTTCTTTATGAAC
CCGATAATTACGGCAGAGCATTTTGAGAAATTGAAAAAGCAATTCCCGGAAATCCCGTCTTATCCCGCTTCGGAAGGAAA
GATCAAGGTTCCGGCCGGTTGGTTGATCGAGCAATGTGGGTTTAAGGGTAAAAACCATGGGTCGGTAGGTGTTTACGAGA
AACAAGCGTTGGTATTAGTGAATTTAGGAGATGCCCGGGGGGATGAGATCGCGTTGGTCGCGGAGAGCATTCGTACCGCC
GTAAAAGATCGTTTCGGTATAGAGCTTATGCCTGAGGTTAAATATGTCGGATAA

Upstream 100 bases:

>100_bases
ACGATCAACTCTATATACAAATCTACTGAAAAAATCCGGAACTACATAATTTGCGGATGAGTTATTTATGACTACTTTTG
CCCTAAAAATAAAATAGACG

Downstream 100 bases:

>100_bases
TGAAAATCGTTTTTTTAGGAACAGGAACGTCTACGGGCAATCCTGAGATAGGTTGCCAATGTGAGGTATGTACTAGTAAA
GACCCCCGTGATTGGCGTCT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRIEQNYSLEKHNTFHLPVKTRWFMEYETEEELQRILHDEYFQECLSLHIGGGSNLLFINDYNGIIIHSRIKGISISAET
DEYVSLRVGAAEIWDDVVAYAVSKGWGGIENLSLIPGEAGAAAIQNIGAYGMEIKDVIESVEAYNQLTFEKRTFTNSDCE
YGYRNSYFKNEHHDPHIITYITLRLSKNPGFSVNYGNLKEELTKYPEVTLETIREAVITIRRQKLPDPEVLGNAGSFFMN
PIITAEHFEKLKKQFPEIPSYPASEGKIKVPAGWLIEQCGFKGKNHGSVGVYEKQALVLVNLGDARGDEIALVAESIRTA
VKDRFGIELMPEVKYVG

Sequences:

>Translated_337_residues
MRIEQNYSLEKHNTFHLPVKTRWFMEYETEEELQRILHDEYFQECLSLHIGGGSNLLFINDYNGIIIHSRIKGISISAET
DEYVSLRVGAAEIWDDVVAYAVSKGWGGIENLSLIPGEAGAAAIQNIGAYGMEIKDVIESVEAYNQLTFEKRTFTNSDCE
YGYRNSYFKNEHHDPHIITYITLRLSKNPGFSVNYGNLKEELTKYPEVTLETIREAVITIRRQKLPDPEVLGNAGSFFMN
PIITAEHFEKLKKQFPEIPSYPASEGKIKVPAGWLIEQCGFKGKNHGSVGVYEKQALVLVNLGDARGDEIALVAESIRTA
VKDRFGIELMPEVKYVG
>Mature_337_residues
MRIEQNYSLEKHNTFHLPVKTRWFMEYETEEELQRILHDEYFQECLSLHIGGGSNLLFINDYNGIIIHSRIKGISISAET
DEYVSLRVGAAEIWDDVVAYAVSKGWGGIENLSLIPGEAGAAAIQNIGAYGMEIKDVIESVEAYNQLTFEKRTFTNSDCE
YGYRNSYFKNEHHDPHIITYITLRLSKNPGFSVNYGNLKEELTKYPEVTLETIREAVITIRRQKLPDPEVLGNAGSFFMN
PIITAEHFEKLKKQFPEIPSYPASEGKIKVPAGWLIEQCGFKGKNHGSVGVYEKQALVLVNLGDARGDEIALVAESIRTA
VKDRFGIELMPEVKYVG

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=332, Percent_Identity=40.3614457831325, Blast_Score=251, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38105; Mature: 38105

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEQNYSLEKHNTFHLPVKTRWFMEYETEEELQRILHDEYFQECLSLHIGGGSNLLFIN
CCCCCCCCCCCCCEEECCEEEEEEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEE
DYNGIIIHSRIKGISISAETDEYVSLRVGAAEIWDDVVAYAVSKGWGGIENLSLIPGEAG
CCCCEEEEEEECCEEEECCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCEECCCCCH
AAAIQNIGAYGMEIKDVIESVEAYNQLTFEKRTFTNSDCEYGYRNSYFKNEHHDPHIITY
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEE
ITLRLSKNPGFSVNYGNLKEELTKYPEVTLETIREAVITIRRQKLPDPEVLGNAGSFFMN
EEEEEECCCCCEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHC
PIITAEHFEKLKKQFPEIPSYPASEGKIKVPAGWLIEQCGFKGKNHGSVGVYEKQALVLV
CCCCHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCCEEEECCEEEEE
NLGDARGDEIALVAESIRTAVKDRFGIELMPEVKYVG
EECCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure
MRIEQNYSLEKHNTFHLPVKTRWFMEYETEEELQRILHDEYFQECLSLHIGGGSNLLFIN
CCCCCCCCCCCCCEEECCEEEEEEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEE
DYNGIIIHSRIKGISISAETDEYVSLRVGAAEIWDDVVAYAVSKGWGGIENLSLIPGEAG
CCCCEEEEEEECCEEEECCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCEECCCCCH
AAAIQNIGAYGMEIKDVIESVEAYNQLTFEKRTFTNSDCEYGYRNSYFKNEHHDPHIITY
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEE
ITLRLSKNPGFSVNYGNLKEELTKYPEVTLETIREAVITIRRQKLPDPEVLGNAGSFFMN
EEEEEECCCCCEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHC
PIITAEHFEKLKKQFPEIPSYPASEGKIKVPAGWLIEQCGFKGKNHGSVGVYEKQALVLV
CCCCHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCCEEEECCEEEEE
NLGDARGDEIALVAESIRTAVKDRFGIELMPEVKYVG
EECCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA