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The map label for this gene is clpC [H]

Identifier: 150007731

GI number: 150007731

Start: 1263377

End: 1265935

Strand: Reverse

Name: clpC [H]

Synonym: BDI_1089

Alternate gene names: 150007731

Gene position: 1265935-1263377 (Counterclockwise)

Preceding gene: 150007734

Following gene: 150007726

Centisome position: 26.31

GC content: 45.33

Gene sequence:

>2559_bases
ATGAAAAATTATTCGAAAAGATTGATTGACGTGATTGAGTATAGCCGTGAAGAAGCGGCTAGGCTCCAGAATAGCTATAT
CGGGCCGGAACATTTGATGCTAGGCATCATCCGGGAAGGCGAAGGCGAGGCAATGCGTGTCTTGCGAGAGCTACATACCG
ATCCGATGGATATTAAACGCAAGATTGAGCAAGAAATAAAGAACACATTCGATTCTGAGGATTCTGTCCAGCATGAGATC
GCTATAAGTAAGACTACAGAACGTGTCTTGCGTATGAGTATGCTGGAATCTCGTTTATTCAAGGAAGATGAGACCGATAC
GGAACATCTTCTATTAGCGATATTGAAAGAGGAGTTTAATGTTGCTGCCAAGGTGTTGAACGATGCGGGTATTACTTATC
GTTCCGCATATAATATATTAGTAAGCGGAACCGGTTTGAACAATATGGAGGAATTCGACGAGATCAGCGACGGATATACG
GATGATGACGAAGATGACGAGGACGAAGGTTTCTCTTCTCGTCGTGAGGCATCTCGCCCCTCTTCCGGTACTGGAGCGGG
AGCCGCTCAACCGAAATCCCCTAATGATACACCTGTTCTGGATAACTTCGGAACGGATATGACACGTGCCGCCGCAGAAA
ACCGTCTAGATCCGATTGTGGGACGTGAGAAGGAAATTGAGCGTTTGGCCCAGATATTAAGCCGTAGGAAGAAAAATAAT
CCGGTATTGATTGGTGAGCCGGGTGTGGGTAAGTCAGCTATCGTAGAGGGATTGGCTTTACGCATTATTCAGCGTAAGGT
TTCCCGGGTGTTATTCGATAAGCGTGTGATTAGCTTGGATATGGCTTCTATTGTCGCTGGTACAAAATACCGCGGACAAT
TCGAGGAACGTATTAAGGCCATCTTGAATGAGTTATCGAAGAACCCGAATATCATCCTCTTTATCGATGAGATTCATACG
ATTGTTGGCGCTGGTTCCGCTTCCGGATCTATGGATGCGGCGAATATGCTGAAACCTGCGTTGGCTCGTGGTGAGATTCA
ATGCATTGGCGCTACTACTTTGGATGAATATCGTAAGAATATCGAGAAAGACGGTGCGTTGGAACGTCGTTTCCAGAAAG
TGATCGTTGATCCGACTACGGCGGAAGAAACTTTGCAGATCTTGCGTAATATCAAACCTCGTTATGAGGAGCACCATAAC
GTGATCTATACTGAAGATGCTTTACAAGCGTGTGTAAAATTGACAGAAAGATATATCAGTGACCGTAATTTCCCAGATAA
GGCGATCGATGCTTTAGACGAGGCCGGTTCCCGTGTACATATATCTAATATCATTGTTCCGAAAAGTATCGAAGAGCTTG
AGGCAAAGATCGAGGATACGAAGAATGAGAAATTAGCGGCCGTGAAATCTCAGAACTTTGAGTTAGCCGCAAGTTTCCGC
GATAAGGAGCGTCAGTATTTATTGCAACTGGAGGCTGCGAAAGCTAAATGGGAACAAGAGCTTCAAGAACATCGGGAGAC
CGTTGATGAAGAGAAGGTCGCTGAAGTTGTTGCCATGATGTCCGGTGTACCTGTTCAACGTATCGCTAAGGCAGAGAATG
TCAAGCTTCTGGAAATGGCGGACGTATTGAAAAGTAAGGTGGTTGGGCAGGATGATGCTGTTCAAAAGATCGTAAAGGCA
ATTCAACGTAACCGTGTTGGCTTGAAAGATCCGAATAAGCCGATCGGAACTTTTATGTTCCTAGGACCGACGGGTGTAGG
TAAAACTCACTTGGCCAAGAAGCTTGCTGAATATCTATTTGATTCGGCGGATTCTTTGGTACGTATCGATATGAGTGAAT
ACTTGGAGAAATTCGCTGTTTCCCGTTTGATCGGAGCGCCTCCCGGATACGTTGGTTACGAGGAAGGTGGTCAGTTAACG
GAGAAAGTACGTCGCAAGCCCTATTCGGTGGTCTTATTGGACGAAATCGAGAAAGCGCATCCGGATGTATTTAACTTGCT
GTTGCAAGTCTTGGATGAAGGCCGTTTGACGGATAGTCTGGGTAGACGTATTGACTTCAAGAATACGATCTTGATCATGA
CTTCCAATATCGGTACCCGGCAATTGAAAGATTTTGGTCGTGGCGTTGGTTTCAATACCCAGATGGCCGGTGAGCCGGAT
AAGGATTTCTCCCGTAGCGTGATCCAGAAAGCGTTGAATAAAGCGTTTGCTCCAGAGTTCTTGAACCGTGTGGATGATAT
CATTATGTTCGATCAGCTTGATAAAGCCGCTATTCATAAGATTATCGATATTGAGTTACAGGGTCTGTATCAGCGTGTAT
CAAATCTGGGCTATGAGTTGTCGATCACAGACGAGGCAAAAGATTTCATTGCCACAAAAGGCTACGATGTCCAATTCGGT
GCCCGTCCGTTGAAGCGTGCGATCCAGAAGTATCTGGAAGATGAGATGGCGGAGATGATTATCCGTGCTTCAGTAGGTGA
AGGCGATACGATTATCGTAGACTTTGATAAGGAAGAGCAGAAAATCACGACTTCGATAAAAAAGAAAGATGCTGAATAA

Upstream 100 bases:

>100_bases
TCGGGCTTTTCAAGGCTTATTAAGGAATAATGGCACGAAATTTGATGATAGTTGGAATAGATTATGTAACTTTGCGTAAT
CAGTACATATATAATATAGT

Downstream 100 bases:

>100_bases
GTTTGTCTATGAATATAGAAGCCGGGCGTGAGTCCGGCTTTTTTTATGTTCGTCCATCTTATTCGTCTGTCATTTTGACA
CACAAAAAAAGCATGACCTA

Product: negative regulator of genetic competence

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 852; Mature: 852

Protein sequence:

>852_residues
MKNYSKRLIDVIEYSREEAARLQNSYIGPEHLMLGIIREGEGEAMRVLRELHTDPMDIKRKIEQEIKNTFDSEDSVQHEI
AISKTTERVLRMSMLESRLFKEDETDTEHLLLAILKEEFNVAAKVLNDAGITYRSAYNILVSGTGLNNMEEFDEISDGYT
DDDEDDEDEGFSSRREASRPSSGTGAGAAQPKSPNDTPVLDNFGTDMTRAAAENRLDPIVGREKEIERLAQILSRRKKNN
PVLIGEPGVGKSAIVEGLALRIIQRKVSRVLFDKRVISLDMASIVAGTKYRGQFEERIKAILNELSKNPNIILFIDEIHT
IVGAGSASGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGALERRFQKVIVDPTTAEETLQILRNIKPRYEEHHN
VIYTEDALQACVKLTERYISDRNFPDKAIDALDEAGSRVHISNIIVPKSIEELEAKIEDTKNEKLAAVKSQNFELAASFR
DKERQYLLQLEAAKAKWEQELQEHRETVDEEKVAEVVAMMSGVPVQRIAKAENVKLLEMADVLKSKVVGQDDAVQKIVKA
IQRNRVGLKDPNKPIGTFMFLGPTGVGKTHLAKKLAEYLFDSADSLVRIDMSEYLEKFAVSRLIGAPPGYVGYEEGGQLT
EKVRRKPYSVVLLDEIEKAHPDVFNLLLQVLDEGRLTDSLGRRIDFKNTILIMTSNIGTRQLKDFGRGVGFNTQMAGEPD
KDFSRSVIQKALNKAFAPEFLNRVDDIIMFDQLDKAAIHKIIDIELQGLYQRVSNLGYELSITDEAKDFIATKGYDVQFG
ARPLKRAIQKYLEDEMAEMIIRASVGEGDTIIVDFDKEEQKITTSIKKKDAE

Sequences:

>Translated_852_residues
MKNYSKRLIDVIEYSREEAARLQNSYIGPEHLMLGIIREGEGEAMRVLRELHTDPMDIKRKIEQEIKNTFDSEDSVQHEI
AISKTTERVLRMSMLESRLFKEDETDTEHLLLAILKEEFNVAAKVLNDAGITYRSAYNILVSGTGLNNMEEFDEISDGYT
DDDEDDEDEGFSSRREASRPSSGTGAGAAQPKSPNDTPVLDNFGTDMTRAAAENRLDPIVGREKEIERLAQILSRRKKNN
PVLIGEPGVGKSAIVEGLALRIIQRKVSRVLFDKRVISLDMASIVAGTKYRGQFEERIKAILNELSKNPNIILFIDEIHT
IVGAGSASGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGALERRFQKVIVDPTTAEETLQILRNIKPRYEEHHN
VIYTEDALQACVKLTERYISDRNFPDKAIDALDEAGSRVHISNIIVPKSIEELEAKIEDTKNEKLAAVKSQNFELAASFR
DKERQYLLQLEAAKAKWEQELQEHRETVDEEKVAEVVAMMSGVPVQRIAKAENVKLLEMADVLKSKVVGQDDAVQKIVKA
IQRNRVGLKDPNKPIGTFMFLGPTGVGKTHLAKKLAEYLFDSADSLVRIDMSEYLEKFAVSRLIGAPPGYVGYEEGGQLT
EKVRRKPYSVVLLDEIEKAHPDVFNLLLQVLDEGRLTDSLGRRIDFKNTILIMTSNIGTRQLKDFGRGVGFNTQMAGEPD
KDFSRSVIQKALNKAFAPEFLNRVDDIIMFDQLDKAAIHKIIDIELQGLYQRVSNLGYELSITDEAKDFIATKGYDVQFG
ARPLKRAIQKYLEDEMAEMIIRASVGEGDTIIVDFDKEEQKITTSIKKKDAE
>Mature_852_residues
MKNYSKRLIDVIEYSREEAARLQNSYIGPEHLMLGIIREGEGEAMRVLRELHTDPMDIKRKIEQEIKNTFDSEDSVQHEI
AISKTTERVLRMSMLESRLFKEDETDTEHLLLAILKEEFNVAAKVLNDAGITYRSAYNILVSGTGLNNMEEFDEISDGYT
DDDEDDEDEGFSSRREASRPSSGTGAGAAQPKSPNDTPVLDNFGTDMTRAAAENRLDPIVGREKEIERLAQILSRRKKNN
PVLIGEPGVGKSAIVEGLALRIIQRKVSRVLFDKRVISLDMASIVAGTKYRGQFEERIKAILNELSKNPNIILFIDEIHT
IVGAGSASGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGALERRFQKVIVDPTTAEETLQILRNIKPRYEEHHN
VIYTEDALQACVKLTERYISDRNFPDKAIDALDEAGSRVHISNIIVPKSIEELEAKIEDTKNEKLAAVKSQNFELAASFR
DKERQYLLQLEAAKAKWEQELQEHRETVDEEKVAEVVAMMSGVPVQRIAKAENVKLLEMADVLKSKVVGQDDAVQKIVKA
IQRNRVGLKDPNKPIGTFMFLGPTGVGKTHLAKKLAEYLFDSADSLVRIDMSEYLEKFAVSRLIGAPPGYVGYEEGGQLT
EKVRRKPYSVVLLDEIEKAHPDVFNLLLQVLDEGRLTDSLGRRIDFKNTILIMTSNIGTRQLKDFGRGVGFNTQMAGEPD
KDFSRSVIQKALNKAFAPEFLNRVDDIIMFDQLDKAAIHKIIDIELQGLYQRVSNLGYELSITDEAKDFIATKGYDVQFG
ARPLKRAIQKYLEDEMAEMIIRASVGEGDTIIVDFDKEEQKITTSIKKKDAE

Specific function: Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=322, Percent_Identity=34.1614906832298, Blast_Score=193, Evalue=5e-49,
Organism=Escherichia coli, GI1788943, Length=877, Percent_Identity=41.733181299886, Blast_Score=644, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=422, Percent_Identity=39.3364928909953, Blast_Score=292, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6320464, Length=708, Percent_Identity=43.6440677966102, Blast_Score=570, Evalue=1e-163,
Organism=Saccharomyces cerevisiae, GI6323002, Length=718, Percent_Identity=36.2116991643454, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 95820; Mature: 95820

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYSKRLIDVIEYSREEAARLQNSYIGPEHLMLGIIREGEGEAMRVLRELHTDPMDIKR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHH
KIEQEIKNTFDSEDSVQHEIAISKTTERVLRMSMLESRLFKEDETDTEHLLLAILKEEFN
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAAKVLNDAGITYRSAYNILVSGTGLNNMEEFDEISDGYTDDDEDDEDEGFSSRREASRP
HHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCC
SSGTGAGAAQPKSPNDTPVLDNFGTDMTRAAAENRLDPIVGREKEIERLAQILSRRKKNN
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
PVLIGEPGVGKSAIVEGLALRIIQRKVSRVLFDKRVISLDMASIVAGTKYRGQFEERIKA
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ILNELSKNPNIILFIDEIHTIVGAGSASGSMDAANMLKPALARGEIQCIGATTLDEYRKN
HHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHH
IEKDGALERRFQKVIVDPTTAEETLQILRNIKPRYEEHHNVIYTEDALQACVKLTERYIS
HCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCEEEEHHHHHHHHHHHHHHHC
DRNFPDKAIDALDEAGSRVHISNIIVPKSIEELEAKIEDTKNEKLAAVKSQNFELAASFR
CCCCCHHHHHHHHHCCCEEEEECEECCCCHHHHHHHHHHCCCHHHHHHHCCCCEEEHHHH
DKERQYLLQLEAAKAKWEQELQEHRETVDEEKVAEVVAMMSGVPVQRIAKAENVKLLEMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHH
DVLKSKVVGQDDAVQKIVKAIQRNRVGLKDPNKPIGTFMFLGPTGVGKTHLAKKLAEYLF
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
DSADSLVRIDMSEYLEKFAVSRLIGAPPGYVGYEEGGQLTEKVRRKPYSVVLLDEIEKAH
CCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHC
PDVFNLLLQVLDEGRLTDSLGRRIDFKNTILIMTSNIGTRQLKDFGRGVGFNTQMAGEPD
CHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCC
KDFSRSVIQKALNKAFAPEFLNRVDDIIMFDQLDKAAIHKIIDIELQGLYQRVSNLGYEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SITDEAKDFIATKGYDVQFGARPLKRAIQKYLEDEMAEMIIRASVGEGDTIIVDFDKEEQ
EECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHH
KITTSIKKKDAE
HHHHHHHHCCCC
>Mature Secondary Structure
MKNYSKRLIDVIEYSREEAARLQNSYIGPEHLMLGIIREGEGEAMRVLRELHTDPMDIKR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHH
KIEQEIKNTFDSEDSVQHEIAISKTTERVLRMSMLESRLFKEDETDTEHLLLAILKEEFN
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAAKVLNDAGITYRSAYNILVSGTGLNNMEEFDEISDGYTDDDEDDEDEGFSSRREASRP
HHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCC
SSGTGAGAAQPKSPNDTPVLDNFGTDMTRAAAENRLDPIVGREKEIERLAQILSRRKKNN
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
PVLIGEPGVGKSAIVEGLALRIIQRKVSRVLFDKRVISLDMASIVAGTKYRGQFEERIKA
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ILNELSKNPNIILFIDEIHTIVGAGSASGSMDAANMLKPALARGEIQCIGATTLDEYRKN
HHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHH
IEKDGALERRFQKVIVDPTTAEETLQILRNIKPRYEEHHNVIYTEDALQACVKLTERYIS
HCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCEEEEHHHHHHHHHHHHHHHC
DRNFPDKAIDALDEAGSRVHISNIIVPKSIEELEAKIEDTKNEKLAAVKSQNFELAASFR
CCCCCHHHHHHHHHCCCEEEEECEECCCCHHHHHHHHHHCCCHHHHHHHCCCCEEEHHHH
DKERQYLLQLEAAKAKWEQELQEHRETVDEEKVAEVVAMMSGVPVQRIAKAENVKLLEMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHH
DVLKSKVVGQDDAVQKIVKAIQRNRVGLKDPNKPIGTFMFLGPTGVGKTHLAKKLAEYLF
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
DSADSLVRIDMSEYLEKFAVSRLIGAPPGYVGYEEGGQLTEKVRRKPYSVVLLDEIEKAH
CCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHC
PDVFNLLLQVLDEGRLTDSLGRRIDFKNTILIMTSNIGTRQLKDFGRGVGFNTQMAGEPD
CHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCC
KDFSRSVIQKALNKAFAPEFLNRVDDIIMFDQLDKAAIHKIIDIELQGLYQRVSNLGYEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SITDEAKDFIATKGYDVQFGARPLKRAIQKYLEDEMAEMIIRASVGEGDTIIVDFDKEEQ
EECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHH
KITTSIKKKDAE
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8016066; 7584024; 9384377; 8195092 [H]