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The map label for this gene is mscM [H]

Identifier: 150007609

GI number: 150007609

Start: 1113739

End: 1114908

Strand: Reverse

Name: mscM [H]

Synonym: BDI_0962

Alternate gene names: 150007609

Gene position: 1114908-1113739 (Counterclockwise)

Preceding gene: 150007617

Following gene: 150007608

Centisome position: 23.17

GC content: 41.03

Gene sequence:

>1170_bases
ATGATAAATTTAGGTAGTTGGATGAACAAAGTCCTCACCGGATGGGGTGTAGACGAGAAAATAGCGAACACATTTGACGA
GGCGATCATCGCCATCTTACTAGTGGCGGTCGCTATCGGATTAGATTATTTATGCCAAGCTATTTTTGTCGGAGGGGTAC
GTAGTATCGTTAAGCATACGCATTATAAATGGGATACGTTATTAATTAAACGTAAGGTCGTACATTATCTCGTACATACG
ATTCCCGGCATTTTAGTATATGTTTTGCTCCCGATGGCTTTTATCCGAGGAAAGGAATTATTATTCATTTCCCAGAAGAT
TTGCGCGATCTATATCATATTTTCCCTGCTGTTAGCGCTCAACGGTCTTCTCTTAATGATGCTGGATTTGTTTAACCAAC
AGGAGAAAATGAAAAACAGGCCGATGAAAGGTTTTATACAAGTATTACAAGTGCTTGTTTTCTTCGTTGGCGGCATTGTC
ATTATAGCGATTCTCGTCAATAAATCCCCGGCTACCCTTTTCGCCGGATTAGGTGCATCGGCAGCTATTCTTATGTTGGT
CTTTAAAGATAGCATATTAGGTTTCGTGGCAGGTATACAGCTTTCGGCGAATGATATGTTGCGCCCCGGCGACTGGATCA
CGATGCCTTCTGCCAATGCGAACGGTATTGTTCAAGAAATAACCCTAAACACCGTGAAAGTTCAGAACTTCGATAATACG
ATCTCGACAATCCCGCCTTATAATCTAGTGAATAGTTCTTTCCAAAACTGGCGCGGGATGGTTGAGTCTGGAGGACGCAG
GGTTATGAAGTCCATTTATCTCGATTTGAATACGATCAAGTTCTGTACGCCGGAGATGCTAGATACCTTCCGCAAGGAAA
TTCCTTTATTAGCGGATTACCAACCGGATAAGGATGTAGTACCTACAAACTCCCAAGTATTCCGTGTATATGTAGAGCGT
TATCTGACAAGTCTTCCTGTCGTAAATCAAGATTTGGATTTAATTATCAGCCAACTTCAATCCACGGAATATGGTGTTCC
CGTCCAGATTTATTTCTTCTCCCGGAATAAAATATGGAAAGAATATGAACGGATCCAGTCGGATATATTCGACCATTTCT
TCGCTATGATTCCTAAATTTGAATTGAAAGTATATCAATATTCAGACTAA

Upstream 100 bases:

>100_bases
TTAATACGCTTACATTTACAAGCAATCTTAACAAAAGGGCAAATTTAACGTAGGATTGAACCTATTTTTAAGAGTAGTGT
TATATCAAAAAACGATTATT

Downstream 100 bases:

>100_bases
AGTACGTGTTCGGATTATTTTTCCTATCTTCGTCTCCGGATTGTCTACTTAAAGTTTAAAATCGTATTTATGAGCAAGAT
ACAAGAATGGGTATATAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MINLGSWMNKVLTGWGVDEKIANTFDEAIIAILLVAVAIGLDYLCQAIFVGGVRSIVKHTHYKWDTLLIKRKVVHYLVHT
IPGILVYVLLPMAFIRGKELLFISQKICAIYIIFSLLLALNGLLLMMLDLFNQQEKMKNRPMKGFIQVLQVLVFFVGGIV
IIAILVNKSPATLFAGLGASAAILMLVFKDSILGFVAGIQLSANDMLRPGDWITMPSANANGIVQEITLNTVKVQNFDNT
ISTIPPYNLVNSSFQNWRGMVESGGRRVMKSIYLDLNTIKFCTPEMLDTFRKEIPLLADYQPDKDVVPTNSQVFRVYVER
YLTSLPVVNQDLDLIISQLQSTEYGVPVQIYFFSRNKIWKEYERIQSDIFDHFFAMIPKFELKVYQYSD

Sequences:

>Translated_389_residues
MINLGSWMNKVLTGWGVDEKIANTFDEAIIAILLVAVAIGLDYLCQAIFVGGVRSIVKHTHYKWDTLLIKRKVVHYLVHT
IPGILVYVLLPMAFIRGKELLFISQKICAIYIIFSLLLALNGLLLMMLDLFNQQEKMKNRPMKGFIQVLQVLVFFVGGIV
IIAILVNKSPATLFAGLGASAAILMLVFKDSILGFVAGIQLSANDMLRPGDWITMPSANANGIVQEITLNTVKVQNFDNT
ISTIPPYNLVNSSFQNWRGMVESGGRRVMKSIYLDLNTIKFCTPEMLDTFRKEIPLLADYQPDKDVVPTNSQVFRVYVER
YLTSLPVVNQDLDLIISQLQSTEYGVPVQIYFFSRNKIWKEYERIQSDIFDHFFAMIPKFELKVYQYSD
>Mature_389_residues
MINLGSWMNKVLTGWGVDEKIANTFDEAIIAILLVAVAIGLDYLCQAIFVGGVRSIVKHTHYKWDTLLIKRKVVHYLVHT
IPGILVYVLLPMAFIRGKELLFISQKICAIYIIFSLLLALNGLLLMMLDLFNQQEKMKNRPMKGFIQVLQVLVFFVGGIV
IIAILVNKSPATLFAGLGASAAILMLVFKDSILGFVAGIQLSANDMLRPGDWITMPSANANGIVQEITLNTVKVQNFDNT
ISTIPPYNLVNSSFQNWRGMVESGGRRVMKSIYLDLNTIKFCTPEMLDTFRKEIPLLADYQPDKDVVPTNSQVFRVYVER
YLTSLPVVNQDLDLIISQLQSTEYGVPVQIYFFSRNKIWKEYERIQSDIFDHFFAMIPKFELKVYQYSD

Specific function: Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock. Overexpression confers protection against severe shocks [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786791, Length=341, Percent_Identity=39.8826979472141, Blast_Score=254, Evalue=9e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 44157; Mature: 44157

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLGSWMNKVLTGWGVDEKIANTFDEAIIAILLVAVAIGLDYLCQAIFVGGVRSIVKHT
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HYKWDTLLIKRKVVHYLVHTIPGILVYVLLPMAFIRGKELLFISQKICAIYIIFSLLLAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHH
NGLLLMMLDLFNQQEKMKNRPMKGFIQVLQVLVFFVGGIVIIAILVNKSPATLFAGLGAS
HHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHH
AAILMLVFKDSILGFVAGIQLSANDMLRPGDWITMPSANANGIVQEITLNTVKVQNFDNT
HHHHHHHHHHHHHHHHHCCEECCCCCCCCCCEEECCCCCCCCCHHEEEECEEEEECCCCC
ISTIPPYNLVNSSFQNWRGMVESGGRRVMKSIYLDLNTIKFCTPEMLDTFRKEIPLLADY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECC
QPDKDVVPTNSQVFRVYVERYLTSLPVVNQDLDLIISQLQSTEYGVPVQIYFFSRNKIWK
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHH
EYERIQSDIFDHFFAMIPKFELKVYQYSD
HHHHHHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MINLGSWMNKVLTGWGVDEKIANTFDEAIIAILLVAVAIGLDYLCQAIFVGGVRSIVKHT
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HYKWDTLLIKRKVVHYLVHTIPGILVYVLLPMAFIRGKELLFISQKICAIYIIFSLLLAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHH
NGLLLMMLDLFNQQEKMKNRPMKGFIQVLQVLVFFVGGIVIIAILVNKSPATLFAGLGAS
HHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHH
AAILMLVFKDSILGFVAGIQLSANDMLRPGDWITMPSANANGIVQEITLNTVKVQNFDNT
HHHHHHHHHHHHHHHHHCCEECCCCCCCCCCEEECCCCCCCCCHHEEEECEEEEECCCCC
ISTIPPYNLVNSSFQNWRGMVESGGRRVMKSIYLDLNTIKFCTPEMLDTFRKEIPLLADY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECC
QPDKDVVPTNSQVFRVYVERYLTSLPVVNQDLDLIISQLQSTEYGVPVQIYFFSRNKIWK
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHH
EYERIQSDIFDHFFAMIPKFELKVYQYSD
HHHHHHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 7813889 [H]