Click here to switch to the map view.

The map label for this gene is mscM [H]

Identifier: 150007608

GI number: 150007608

Start: 1112374

End: 1113669

Strand: Reverse

Name: mscM [H]

Synonym: BDI_0961

Alternate gene names: 150007608

Gene position: 1113669-1112374 (Counterclockwise)

Preceding gene: 150007609

Following gene: 150007585

Centisome position: 23.15

GC content: 41.05

Gene sequence:

>1296_bases
ATGAGCAAGATACAAGAATGGGTATATAATTTATTAGTTCAAATGGGGTTGATAAGCGAAAATTCCAGTTACCTAGACAA
TATAGTGATCTTATTACTTATTATAGCCGTCACCGTTGGGATCGATTATAGTTGCCGGTATATTTTCCTAGGTATGTTCA
AACGATTAGCGAGGAAGACGAAAAATCAACTGGATGATTTAATCGTGGATCGTAAGATCATCAATAAGATGATGCATATG
ATCCCGGCCATATTGATTTATATATTGTTACCATTCGCCTTCTCAGCCGAAGAGACACCGAAGATTTTAATAGTACTCCA
AAAACTTTGTCAGATTTATATCATAGCGGTTTCTTTAAGGTTTATAAACGCTTCCTTAAATCTGATCCACGAGATCTATA
ATAAAAAAGATTCCTTTAAGAACAAGCCGTTAAAAGGCTTCATACAGATCTTGCAGGTTACGGTTTTCTTTATTGGGGTG
ATATTGATTATCAGTATTCTTATCAATAAATCCCCGGTTTCTTTACTGGCCGGATTGGGTGCGTCTGCCGCTATCTTGAT
GTTGGTCTTTAAGGATACGATCTTAGGTTTCGTTGCCGGCATCCAATTATCCGCCAATGATATGCTCCGGGCCGGAGACT
GGATCACGATGAGTAAATATGGTGCGGACGGCACGGTTATCGAGGTGACATTGAACGCCGTGAAAGTAAGAAACTTTGAC
AATACCATTACGACCATCCCTCCTTACGCCTTAGTAAGCGACGCTTTCCAAAACTGGAGAGGTATGAGCGAATCCCCGGG
CCGCCGTATCAAGCGCTCTATCAATATCGATATGAACAGCGTACATTTTTGTACCCCGGAAATGCTAGAGAAATTTCGTA
AGATCTCTCTTATCACGGATTACATCGATGGAAAAGAACAGGAATTAGATGAATATAATGAAGAACATCATATCGATAGT
TCCATTTGGGTGAACGGACGTAGACAAACAAATCTGGGTGTCTTCCGTGCTTATCTCGTACGTTACCTAAGAAGCCTCCC
GGAAGTAAGTAAGGAATTAGTCTGCATGGTAAGGCATCTACAACCGACTGATACAGGTATTCCCATCGAACTTTATTGCT
TCTCATCCAATAAGGTATGGGTCGAATATGAAGGAATTCAAGCGGATATATTCGACCATGTACTTGCAGTAATACCGGAG
TTTGGGCTAAGCGTATTCCAAAATGTATCCGGGGCGGATTTGAAGAATATCATCATCAAACTTCCCGCCGGCTCACAACC
CTCAGAGTGTTTCTAG

Upstream 100 bases:

>100_bases
TGAATTGAAAGTATATCAATATTCAGACTAAAGTACGTGTTCGGATTATTTTTCCTATCTTCGTCTCCGGATTGTCTACT
TAAAGTTTAAAATCGTATTT

Downstream 100 bases:

>100_bases
AAACTCATGTACATGTTTTTCCGGAAATGATAGGAACACTCTAAGATGTCAAAAAAATATCTTAGGTGCATCGGCCGACG
ATCCTAAGATACTTCGCCAG

Product: putative membrane transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSKIQEWVYNLLVQMGLISENSSYLDNIVILLLIIAVTVGIDYSCRYIFLGMFKRLARKTKNQLDDLIVDRKIINKMMHM
IPAILIYILLPFAFSAEETPKILIVLQKLCQIYIIAVSLRFINASLNLIHEIYNKKDSFKNKPLKGFIQILQVTVFFIGV
ILIISILINKSPVSLLAGLGASAAILMLVFKDTILGFVAGIQLSANDMLRAGDWITMSKYGADGTVIEVTLNAVKVRNFD
NTITTIPPYALVSDAFQNWRGMSESPGRRIKRSINIDMNSVHFCTPEMLEKFRKISLITDYIDGKEQELDEYNEEHHIDS
SIWVNGRRQTNLGVFRAYLVRYLRSLPEVSKELVCMVRHLQPTDTGIPIELYCFSSNKVWVEYEGIQADIFDHVLAVIPE
FGLSVFQNVSGADLKNIIIKLPAGSQPSECF

Sequences:

>Translated_431_residues
MSKIQEWVYNLLVQMGLISENSSYLDNIVILLLIIAVTVGIDYSCRYIFLGMFKRLARKTKNQLDDLIVDRKIINKMMHM
IPAILIYILLPFAFSAEETPKILIVLQKLCQIYIIAVSLRFINASLNLIHEIYNKKDSFKNKPLKGFIQILQVTVFFIGV
ILIISILINKSPVSLLAGLGASAAILMLVFKDTILGFVAGIQLSANDMLRAGDWITMSKYGADGTVIEVTLNAVKVRNFD
NTITTIPPYALVSDAFQNWRGMSESPGRRIKRSINIDMNSVHFCTPEMLEKFRKISLITDYIDGKEQELDEYNEEHHIDS
SIWVNGRRQTNLGVFRAYLVRYLRSLPEVSKELVCMVRHLQPTDTGIPIELYCFSSNKVWVEYEGIQADIFDHVLAVIPE
FGLSVFQNVSGADLKNIIIKLPAGSQPSECF
>Mature_430_residues
SKIQEWVYNLLVQMGLISENSSYLDNIVILLLIIAVTVGIDYSCRYIFLGMFKRLARKTKNQLDDLIVDRKIINKMMHMI
PAILIYILLPFAFSAEETPKILIVLQKLCQIYIIAVSLRFINASLNLIHEIYNKKDSFKNKPLKGFIQILQVTVFFIGVI
LIISILINKSPVSLLAGLGASAAILMLVFKDTILGFVAGIQLSANDMLRAGDWITMSKYGADGTVIEVTLNAVKVRNFDN
TITTIPPYALVSDAFQNWRGMSESPGRRIKRSINIDMNSVHFCTPEMLEKFRKISLITDYIDGKEQELDEYNEEHHIDSS
IWVNGRRQTNLGVFRAYLVRYLRSLPEVSKELVCMVRHLQPTDTGIPIELYCFSSNKVWVEYEGIQADIFDHVLAVIPEF
GLSVFQNVSGADLKNIIIKLPAGSQPSECF

Specific function: Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock. Overexpression confers protection against severe shocks [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786791, Length=390, Percent_Identity=42.3076923076923, Blast_Score=328, Evalue=4e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 48841; Mature: 48710

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIQEWVYNLLVQMGLISENSSYLDNIVILLLIIAVTVGIDYSCRYIFLGMFKRLARKT
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KNQLDDLIVDRKIINKMMHMIPAILIYILLPFAFSAEETPKILIVLQKLCQIYIIAVSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FINASLNLIHEIYNKKDSFKNKPLKGFIQILQVTVFFIGVILIISILINKSPVSLLAGLG
HHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
ASAAILMLVFKDTILGFVAGIQLSANDMLRAGDWITMSKYGADGTVIEVTLNAVKVRNFD
HHHHHHHHHHHHHHHHHHHCCEECCCHHHHCCCEEEEECCCCCCCEEEEEEEEEEEECCC
NTITTIPPYALVSDAFQNWRGMSESPGRRIKRSINIDMNSVHFCTPEMLEKFRKISLITD
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHH
YIDGKEQELDEYNEEHHIDSSIWVNGRRQTNLGVFRAYLVRYLRSLPEVSKELVCMVRHL
HCCCCHHHHHHCCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPTDTGIPIELYCFSSNKVWVEYEGIQADIFDHVLAVIPEFGLSVFQNVSGADLKNIIIK
CCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
LPAGSQPSECF
CCCCCCCCCCC
>Mature Secondary Structure 
SKIQEWVYNLLVQMGLISENSSYLDNIVILLLIIAVTVGIDYSCRYIFLGMFKRLARKT
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KNQLDDLIVDRKIINKMMHMIPAILIYILLPFAFSAEETPKILIVLQKLCQIYIIAVSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FINASLNLIHEIYNKKDSFKNKPLKGFIQILQVTVFFIGVILIISILINKSPVSLLAGLG
HHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
ASAAILMLVFKDTILGFVAGIQLSANDMLRAGDWITMSKYGADGTVIEVTLNAVKVRNFD
HHHHHHHHHHHHHHHHHHHCCEECCCHHHHCCCEEEEECCCCCCCEEEEEEEEEEEECCC
NTITTIPPYALVSDAFQNWRGMSESPGRRIKRSINIDMNSVHFCTPEMLEKFRKISLITD
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHH
YIDGKEQELDEYNEEHHIDSSIWVNGRRQTNLGVFRAYLVRYLRSLPEVSKELVCMVRHL
HCCCCHHHHHHCCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPTDTGIPIELYCFSSNKVWVEYEGIQADIFDHVLAVIPEFGLSVFQNVSGADLKNIIIK
CCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
LPAGSQPSECF
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 7813889 [H]