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The map label for this gene is gpmA

Identifier: 150007251

GI number: 150007251

Start: 696988

End: 697734

Strand: Reverse

Name: gpmA

Synonym: BDI_0596

Alternate gene names: 150007251

Gene position: 697734-696988 (Counterclockwise)

Preceding gene: 150007252

Following gene: 150007250

Centisome position: 14.5

GC content: 48.19

Gene sequence:

>747_bases
ATGAAAAGTATCGTATTGCTTCGCCACGGCGAAAGTATATGGAATAAAGAGAACCGGTTCACCGGTTGGACCGATGTGGA
TTTGACAGAAAAAGGCGTGGCCGAAGCTTATAGGGCCGGCAACCTATTGAAAGAAAAAGGATATGTGTTCAATAAAGCCT
ATACCTCTTATTTAAAACGGGCCGTCAAAACCTTGAATTGTGTATTGGATCGCATGGACCAAGACTGGATCCCGGTGGAG
AAGAGCTGGAGGCTGAACGAGAAACATTACGGATCGCTACAAGGGTTGAACAAGAGCGAGACCGCCCAAAAGTATGGAGA
CGAGCAGGTCTTGATCTGGCGTCGCAGTTACGATATAGCCCCGCTTCCCCTATCGGAAGACGACCCTCGTAACCCTCGCT
TCGATATCCGCTACAAAGACGTGCCGGATAAAGAGTTGCCCCGTACGGAATCCTTGAAAGATACGGTTGAGCGGATTCTC
CCTTATTGGAAAGAGGTTATCTTCCCGACGCTCCGGACCGCCGACCAGATCCTTGTCGCCGCTCACGGAAACAGCTTGCG
GGGAATCATCAAATATTTAAAAAACATCTCCGATGAAGAGATCGTTCATCTGAATCTCCCAACAGCCGTTCCATACGTGT
TCGAGTTCGATGATGACTTAAAACTCGTGAATGATTATTTCCTTGGCGACCCGGAGGAAATCAAGAAACTCATGGAAGCC
GTAGCCAACCAAGGAAAGAAAAAGTAG

Upstream 100 bases:

>100_bases
TCCTCACGGCAGCGAAGGATGTACAACATAGTCATCTACCTATATTAAAAGAAGTCATCGAGGATTTCGAAAAAAACAAA
TCATAAAAATAAAAAGACCT

Downstream 100 bases:

>100_bases
CGGGATTCATGCCTCTTATCCGGAATTATTCATTAAGTTTGCAACCAAACAAACTTAAACACTATTGTGGACGAGAACGC
AGAACGAATTTCACTAGAAC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKSIVLLRHGESIWNKENRFTGWTDVDLTEKGVAEAYRAGNLLKEKGYVFNKAYTSYLKRAVKTLNCVLDRMDQDWIPVE
KSWRLNEKHYGSLQGLNKSETAQKYGDEQVLIWRRSYDIAPLPLSEDDPRNPRFDIRYKDVPDKELPRTESLKDTVERIL
PYWKEVIFPTLRTADQILVAAHGNSLRGIIKYLKNISDEEIVHLNLPTAVPYVFEFDDDLKLVNDYFLGDPEEIKKLMEA
VANQGKKK

Sequences:

>Translated_248_residues
MKSIVLLRHGESIWNKENRFTGWTDVDLTEKGVAEAYRAGNLLKEKGYVFNKAYTSYLKRAVKTLNCVLDRMDQDWIPVE
KSWRLNEKHYGSLQGLNKSETAQKYGDEQVLIWRRSYDIAPLPLSEDDPRNPRFDIRYKDVPDKELPRTESLKDTVERIL
PYWKEVIFPTLRTADQILVAAHGNSLRGIIKYLKNISDEEIVHLNLPTAVPYVFEFDDDLKLVNDYFLGDPEEIKKLMEA
VANQGKKK
>Mature_248_residues
MKSIVLLRHGESIWNKENRFTGWTDVDLTEKGVAEAYRAGNLLKEKGYVFNKAYTSYLKRAVKTLNCVLDRMDQDWIPVE
KSWRLNEKHYGSLQGLNKSETAQKYGDEQVLIWRRSYDIAPLPLSEDDPRNPRFDIRYKDVPDKELPRTESLKDTVERIL
PYWKEVIFPTLRTADQILVAAHGNSLRGIIKYLKNISDEEIVHLNLPTAVPYVFEFDDDLKLVNDYFLGDPEEIKKLMEA
VANQGKKK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=248, Percent_Identity=52.8225806451613, Blast_Score=276, Evalue=1e-74,
Organism=Homo sapiens, GI4505753, Length=248, Percent_Identity=54.4354838709677, Blast_Score=271, Evalue=6e-73,
Organism=Homo sapiens, GI71274132, Length=248, Percent_Identity=52.0161290322581, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI4502445, Length=250, Percent_Identity=47.6, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI40353764, Length=250, Percent_Identity=47.6, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=55.625, Blast_Score=174, Evalue=5e-44,
Organism=Escherichia coli, GI1786970, Length=245, Percent_Identity=60.4081632653061, Blast_Score=313, Evalue=6e-87,
Organism=Saccharomyces cerevisiae, GI6322697, Length=247, Percent_Identity=50.2024291497976, Blast_Score=249, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6320183, Length=297, Percent_Identity=31.3131313131313, Blast_Score=136, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324516, Length=294, Percent_Identity=30.2721088435374, Blast_Score=135, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24646216, Length=249, Percent_Identity=53.4136546184739, Blast_Score=268, Evalue=3e-72,
Organism=Drosophila melanogaster, GI85725270, Length=249, Percent_Identity=52.6104417670683, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI85725272, Length=249, Percent_Identity=52.6104417670683, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24650981, Length=249, Percent_Identity=52.6104417670683, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI28571817, Length=254, Percent_Identity=39.7637795275591, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI28571815, Length=254, Percent_Identity=39.7637795275591, Blast_Score=174, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24648979, Length=254, Percent_Identity=39.7637795275591, Blast_Score=174, Evalue=4e-44,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_PARD8 (A6L9K8)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001301994.1
- ProteinModelPortal:   A6L9K8
- SMR:   A6L9K8
- STRING:   A6L9K8
- GeneID:   5305751
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0596
- eggNOG:   COG0588
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK14115
- BioCyc:   PDIS435591:BDI_0596-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 28893; Mature: 28893

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIVLLRHGESIWNKENRFTGWTDVDLTEKGVAEAYRAGNLLKEKGYVFNKAYTSYLKR
CCCEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHH
AVKTLNCVLDRMDQDWIPVEKSWRLNEKHYGSLQGLNKSETAQKYGDEQVLIWRRSYDIA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCHHCCCCHHHHHHHHCCCEEEEEECCCCCC
PLPLSEDDPRNPRFDIRYKDVPDKELPRTESLKDTVERILPYWKEVIFPTLRTADQILVA
CCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AHGNSLRGIIKYLKNISDEEIVHLNLPTAVPYVFEFDDDLKLVNDYFLGDPEEIKKLMEA
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHH
VANQGKKK
HHHCCCCC
>Mature Secondary Structure
MKSIVLLRHGESIWNKENRFTGWTDVDLTEKGVAEAYRAGNLLKEKGYVFNKAYTSYLKR
CCCEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHH
AVKTLNCVLDRMDQDWIPVEKSWRLNEKHYGSLQGLNKSETAQKYGDEQVLIWRRSYDIA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCHHCCCCHHHHHHHHCCCEEEEEECCCCCC
PLPLSEDDPRNPRFDIRYKDVPDKELPRTESLKDTVERILPYWKEVIFPTLRTADQILVA
CCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AHGNSLRGIIKYLKNISDEEIVHLNLPTAVPYVFEFDDDLKLVNDYFLGDPEEIKKLMEA
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHH
VANQGKKK
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA